Miklós Tóth

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: ACS CHEMICAL NEUROSCIENCE. 2021;12(24):4580-4586

PET Imaging of VMAT2 with the Novel Radioligand [18F]FE-DTBZ-d4 in Nonhuman Primates: Comparison with [11C]DTBZ and [18F]FE-DTBZ.

Nag S; Jahan M; Tóth M; Nakao R; Varrone A; Halldin C
Article: BIOCONJUGATE CHEMISTRY. 2021;32(3):497-501

Multiple Applications of a Novel Biarsenical Imaging Probe in Fluorescence and PET Imaging of Melanoma.

Kondrashov M; Svensson SPS; Ström P; Westermark A; Jacobson-Ingemyr H; Takano A; Tari L; Tóth M; Cai M; Hruby VJ; Schou M
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2020;63(15):8608-8633

Imaging Mutant Huntingtin Aggregates: Development of a Potential PET Ligand.

Liu L; Prime ME; Lee MR; Khetarpal V; Brown CJ; Johnson PD; Miranda-Azpiazu P; Chen X; Clark-Frew D; Coe S; Davis R; Dickie A; Ebneth A; Esposito S; Gadouleau E; Gai X; Galan S; Green S; Greenaway C; Giles P; Halldin C; Hayes S; Herbst T; Herrmann F; Heßmann M; Jia Z; Kiselyov A; Kotey A; Krulle T; Mangette JE; Marston RW; Menta S; Mills MR; Monteagudo E; Nag S; Nibbio M; Orsatti L; Schaertl S; Scheich C; Sproston J; Stepanov V; Svedberg M; Takano A; Taylor M; Thomas W; Toth M; Vaidya D; Vanräs K; Weddell D; Wigginton I; Wityak J; Mrzljak L; Munoz-Sanjuan I; Bard JA; Dominguez C
Article: ACS CHEMICAL NEUROSCIENCE. 2020;11(12):1756-1761

Synthesis and Preclinical Evaluation of 6-[18F]Fluorine-α-methyl-l-tryptophan, a Novel PET Tracer for Measuring Tryptophan Uptake.

Krasikova R; Kondrashov M; Avagliano C; Petukhov M; Vazquez-Romero A; Revunov E; Johnström P; Tari L; Tóth M; Häggkvist J; Erhardt S; Cervenka S; Schou M
Article: TALANTA. 2020;208:120449

New approach in radiometabolite analysis of positron emission tomography (PET) radioligands; lead-shielded microextraction by packed sorbent as a tool for in vivo radiometabolite analysis of [11C]SMW139 in rat plasma.

Moein MM; Tóth M; Tari L; Varrone A; Abdel-Rehim M; Halldin C
Article: JOURNAL OF NUCLEAR MEDICINE. 2019;60(12):1818-1824

Performance Evaluation of a High-Resolution Nonhuman Primate PET/CT System.

Sarnyai Z; Nagy K; Patay G; Molnár M; Rosenqvist G; Tóth M; Takano A; Gulyás B; Major P; Halldin C; Varrone A
Article: NATURE MEDICINE. 2019;25(7):1131-1142

Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease.

Zeitler B; Froelich S; Marlen K; Shivak DA; Yu Q; Li D; Pearl JR; Miller JC; Zhang L; Paschon DE; Hinkley SJ; Ankoudinova I; Lam S; Guschin D; Kopan L; Cherone JM; Nguyen H-OB; Qiao G; Ataei Y; Mendel MC; Amora R; Surosky R; Laganiere J; Vu BJ; Narayanan A; Sedaghat Y; Tillack K; Thiede C; Gärtner A; Kwak S; Bard J; Mrzljak L; Park L; Heikkinen T; Lehtimäki KK; Svedberg MM; Häggkvist J; Tari L; Tóth M; Varrone A; Halldin C; Kudwa AE; Ramboz S; Day M; Kondapalli J; Surmeier DJ; Urnov FD; Gregory PD; Rebar EJ; Muñoz-Sanjuán I; Zhang HS
Article: EUROPEAN PSYCHIATRY. 2018;50:21-27

The MINDVIEW project: First results.

Benlloch JM; González AJ; Pani R; Preziosi E; Jackson C; Murphy J; Barberá J; Correcher C; Aussenhofer S; Gareis D; Visvikis D; Bert J; Langstrom B; Farde L; Toth M; Haggkvist J; Caixeta FV; Kullander K; Somlai-Schweiger I; Schwaiger M
Article: JOURNAL OF ALZHEIMER'S DISEASE REPORTS. 2017;1(1):169-180

Differential Effect of APOE Alleles on Brain Glucose Metabolism in Targeted Replacement Mice: An [18F]FDG-μPET Study.

Venzi M; Tóth M; Häggkvist J; Bogstedt A; Rachalski A; Mattsson A; Frumento P; Farde L
Article: JOURNAL OF NUCLEAR MEDICINE. 2017;58(4):617-622

Longitudinal Small-Animal PET Imaging of the zQ175 Mouse Model of Huntington Disease Shows In Vivo Changes of Molecular Targets in the Striatum and Cerebral Cortex.

Häggkvist J; Tóth M; Tari L; Varnäs K; Svedberg M; Forsberg A; Nag S; Dominguez C; Munoz-Sanjuan I; Bard J; Wityak J; Varrone A; Halldin C; Mrzljak L
Article: CURRENT RADIOPHARMACEUTICALS. 2017;10(1):35-40

Development of a Novel Carbon-11 Labeled PET Radioligand for Melanin- Concentrating Hormone Receptor 1.

Igawa H; Stepanov V; Tari L; Okuda S; Yamamoto S; Kasai S; Nagisa Y; Haggkvist J; Svedberg M; Toth M; Takano A; Halldin C
Article: NEURON. 2016;92(6):1220-1237

Phosphodiesterase 10A Inhibition Improves Cortico-Basal Ganglia Function in Huntington's Disease Models.

Beaumont V; Zhong S; Lin H; Xu W; Bradaia A; Steidl E; Gleyzes M; Wadel K; Buisson B; Padovan-Neto FE; Chakroborty S; Ward KM; Harms JF; Beltran J; Kwan M; Ghavami A; Häggkvist J; Tóth M; Halldin C; Varrone A; Schaab C; Dybowski JN; Elschenbroich S; Lehtimäki K; Heikkinen T; Park L; Rosinski J; Mrzljak L; Lavery D; West AR; Schmidt CJ; Zaleska MM; Munoz-Sanjuan I
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2016;19(8):pyw023

Neurokinin-3 Receptor Binding in Guinea Pig, Monkey, and Human Brain: In Vitro and in Vivo Imaging Using the Novel Radioligand, [18F]Lu AF10628.

Varnäs K; Finnema SJ; Stepanov V; Takano A; Tóth M; Svedberg M; Møller Nielsen S; Khanzhin NA; Juhl K; Bang-Andersen B; Halldin C; Farde L
Article: BRAIN STRUCTURE & FUNCTION. 2016;221(3):1279-1290

Acute neuroinflammation in a clinically relevant focal cortical ischemic stroke model in rat: longitudinal positron emission tomography and immunofluorescent tracking.

Tóth M; Little P; Arnberg F; Häggkvist J; Mulder J; Halldin C; Gulyás B; Holmin S
Article: MOLECULAR IMAGING AND BIOLOGY. 2015;17(4):445-449

Molecular Imaging of PDE10A Knockout Mice with a Novel PET Radiotracer: [(11)C]T-773.

Tóth M; Häggkvist J; Stepanov V; Takano A; Nakao R; Amini N; Miura S; Kimura H; Taniguchi T; Gulyás B; Halldin C
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2015;42(7):1119-1132

Astrocytosis precedes amyloid plaque deposition in Alzheimer APPswe transgenic mouse brain: a correlative positron emission tomography and in vitro imaging study.

Rodriguez-Vieitez E; Ni R; Gulyás B; Tóth M; Häggkvist J; Halldin C; Voytenko L; Marutle A; Nordberg A
Article: PLOS ONE. 2015;10(5):e0125917

Positron Emission Tomography studies with [11C]PBR28 in the Healthy Rodent Brain: Validating SUV as an Outcome Measure of Neuroinflammation.

Tóth M; Doorduin J; Häggkvist J; Varrone A; Amini N; Halldin C; Gulyás B
Article: EJNMMI RESEARCH. 2014;4(1):64

ABC transporter-dependent brain uptake of the 5-HT1B receptor radioligand [ (11)C]AZ10419369: a comparative PET study in mouse, rat, and guinea pig.

Tóth M; Häggkvist J; Varrone A; Finnema SJ; Doorduin J; Tokunaga M; Higuchi M; Gulyás B; Halldin C
Article: SCIENCE TRANSLATIONAL MEDICINE. 2014;6(263):263ra158

The gut microbiota influences blood-brain barrier permeability in mice.

Braniste V; Al-Asmakh M; Kowal C; Anuar F; Abbaspour A; Tóth M; Korecka A; Bakocevic N; Ng LG; Kundu P; Gulyás B; Halldin C; Hultenby K; Nilsson H; Hebert H; Volpe BT; Diamond B; Pettersson S
Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2013;21(21):6634-6641

Development of a novel fluorine-18 labeled deuterated fluororasagiline ([(18)F]fluororasagiline-D2) radioligand for PET studies of monoamino oxidase B (MAO-B).

Nag S; Lehmann L; Kettschau G; Toth M; Heinrich T; Thiele A; Varrone A; Halldin C
Article: JOURNAL OF NUCLEAR MEDICINE. 2013;54(10):1825-1832

Performance evaluation of the small-animal nanoScan PET/MRI system.

Nagy K; Tóth M; Major P; Patay G; Egri G; Häggkvist J; Varrone A; Farde L; Halldin C; Gulyás B
Article: SYNAPSE. 2013;67(5):258-264

Brain uptake and distribution of the dopamine D3 /D2 receptor partial agonist [11 C]cariprazine: an in vivo positron emission tomography study in nonhuman primates.

Tóth M; Varrone A; Steiger C; Laszlovszky I; Horváth A; Kiss B; Gyertyán I; Adham N; Halldin C; Gulyás B
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2013;40(2):228-237

Improved mapping and quantification of serotonin transporter availability in the human brainstem with the HRRT.

Schain M; Tóth M; Cselényi Z; Arakawa R; Halldin C; Farde L; Varrone A
Article: JOURNAL OF NUCLEAR MEDICINE. 2012;53(11):1794-1801

Preclinical characterization of a novel class of 18F-labeled PET tracers for amyloid-β.

Brockschnieder D; Schmitt-Willich H; Heinrich T; Varrone A; Gulyás B; Toth M; Andersson J; Boemer U; Krause S; Friebe M; Dinkelborg L; Halldin C; Dyrks T
Article: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2012;320(1-2):110-117

Evolution of microglial activation in ischaemic core and peri-infarct regions after stroke: a PET study with the TSPO molecular imaging biomarker [((11))C]vinpocetine.

Gulyás B; Tóth M; Schain M; Airaksinen A; Vas A; Kostulas K; Lindström P; Hillert J; Halldin C
Article: SYNAPSE. 2012;66(4):323-330

In vivo evaluation in cynomolgus monkey brain and metabolism of [¹⁸F]fluorodeprenyl: a new MAO-B pet radioligand.

Nag S; Varrone A; Tóth M; Thiele A; Kettschau G; Heinrich T; Lehmann L; Halldin C
Article: NEUROIMAGE. 2012;60(1):800-807

Quantification of serotonin transporter availability with [11C]MADAM--a comparison between the ECAT HRRT and HR systems.

Schain M; Tóth M; Cselényi Z; Stenkrona P; Halldin C; Farde L; Varrone A
Article: CURRENT RADIOPHARMACEUTICALS. 2012;5(1):19-28

Visualising neuroinflammation in post-stroke patients: a comparative PET study with the TSPO molecular imaging biomarkers [11C]PK11195 and [11C]vinpocetine.

Gulyas B; Toth M; Vas A; Shchukin E; Kostulas K; Hillert J; Halldin C
Article: JOURNAL OF NUCLEAR MEDICINE. 2011;52(8):1313-1321

Imaging of the striatal and extrastriatal dopamine transporter with (18)F-LBT-999: quantification, biodistribution, and radiation dosimetry in nonhuman primates.

Varrone A; Stepanov V; Nakao R; Tóth M; Gulyás B; Emond P; Deloye JB; Vercouillie J; Stabin MG; Jonsson C; Guilloteau D; Halldin C
Article: NEUROIMAGE. 2011;56(3):1111-1121

Age and disease related changes in the translocator protein (TSPO) system in the human brain: positron emission tomography measurements with [11C]vinpocetine.

Gulyás B; Vas A; Tóth M; Takano A; Varrone A; Cselényi Z; Schain M; Mattsson P; Halldin C
Article: JOURNAL OF NUCLEAR MEDICINE. 2011;52(1):132-139

Kinetic analysis and quantification of the dopamine transporter in the nonhuman primate brain with 11C-PE2I and 18F-FE-PE2I.

Varrone A; Tóth M; Steiger C; Takano A; Guilloteau D; Ichise M; Gulyás B; Halldin C
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KI thesis / dissertation: 2015

Methodological developments in small animal PET neuroimaging

Tóth, Miklós

Anställningar

Forskningsspecialist, Klinisk neurovetenskap, Karolinska Institutet, 2022-

Examina och utbildning

Medicine Doktorsexamen, Institutionen för klinisk neurovetenskap, Karolinska Institutet, 2015

Artiklar

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Examina och utbildning

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