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Markus Dagnell

Postdoc

Publikationer

Thioredoxin reductase 1 and NADPH directly protect protein tyrosine phosphatase 1B from inactivation during HO exposure
Dagnell M, Pace Pe, Cheng Q, Frijhoff J, Östman A, Arnér Esj, et al
The Journal of biological chemistry 2017;292(35):14371-14380

Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis
Hellfritsch J, Kirsch J, Schneider M, Fluege T, Wortmann M, Frijhoff J, et al
Antioxidants & redox signaling 2015;22(11):938-50

Inhibition of protein tyrosine phosphatases enhances cerebral collateral growth in rats
Buschmann I, Hackbusch D, Gatzke N, Dülsner A, Trappiel M, Dagnell M, et al
Journal of molecular medicine (Berlin, Germany) 2014;92(9):983-94

Regulation of protein tyrosine phosphatase oxidation in cell adhesion and migration
Frijhoff J, Dagnell M, Godfrey R, Ostman A
Antioxidants & redox signaling 2014;20(13):1994-2010

The mitochondrial reactive oxygen species regulator p66Shc controls PDGF-induced signaling and migration through protein tyrosine phosphatase oxidation
Frijhoff J, Dagnell M, Augsten M, Beltrami E, Giorgio M, Östman A
Free radical biology & medicine 2014;68():268-77

Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-β receptor tyrosine kinase signaling
Dagnell M, Frijhoff J, Pader I, Augsten M, Boivin B, Xu J, et al
Proceedings of the National Academy of Sciences of the United States of America 2013;110(33):13398-403

Targeting density-enhanced phosphatase-1 (DEP-1) with antisense oligonucleotides improves the metabolic phenotype in high-fat diet-fed mice
Krüger J, Trappiel M, Dagnell M, Stawowy P, Meyborg H, Böhm C, et al
Cell communication and signaling : CCS 2013;11():49-

Cell transformation by FLT3 ITD in acute myeloid leukemia involves oxidative inactivation of the tumor suppressor protein-tyrosine phosphatase DEP-1/ PTPRJ
Godfrey R, Arora D, Bauer R, Stopp S, Müller Jp, Heinrich T, et al
Blood 2012;119(19):4499-511

Hypoxia Enhances Platelet-derived Growth Factor Signaling in the Pulmonary Vasculature by Down-Regulation of Protein Tyrosine Phosphatases
Ten Freyhaus H, Dagnell M, Leuchs M, Vantler M, Berghausen Em, Caglayan E, et al
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 2011;183(8):1092-102

Hypoxia followed by re-oxygenation induces oxidation of tyrosine phosphatases
Sandin A, Dagnell M, Gonon A, Pernow J, Stangl V, Aspenstrom P, et al
CELLULAR SIGNALLING 2011;23(5):820-6

12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases
Conrad M, Sandin A, Forster H, Seiler A, Frijhoff J, Dagnell M, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2010;107(36):15774-9

FBXW7/hCDC4 is a general tumor suppressor in human cancer
Akhoondi S, Sun D, Von Der Lehr N, Apostolidou S, Klotz K, Maljukova A, et al
CANCER RESEARCH 2007;67(19):9006-12

Oxidation sensitivity of the catalytic cysteine of the protein-tyrosine phosphatases SHP-1 and SHP-2
Weibrecht I, Bohmer Sa, Dagnell M, Kappert K, Ostman A, Bohmer Fd
FREE RADICAL BIOLOGY AND MEDICINE 2007;43(1):100-10

Interferon alpha-induced apoptosis in tumor cells is mediated through the phosphoinositide 3-kinase/mammalian target of rapamycin signaling pathway
Thyrell L, Hjortsberg L, Arulampalam V, Panaretakis T, Uhles S, Dagnell M, et al
JOURNAL OF BIOLOGICAL CHEMISTRY 2004;279(23):24152-62

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