Lara Kular

Om mig
Publikationer
Populärvetenskap och samverkan

Om mig

I am Assistant Professor in Maja Jagodic's group of the Neuroimmunology Unit.

Artiklar

Article: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2023;79:104991

Smoking affects epigenetic ageing of lung bronchoalveolar lavage cells in Multiple Sclerosis.

Klose D; Needhamsen M; Ringh MV; Hagemann-Jensen M; Jagodic M; Kular L
Article: JOURNAL OF PSYCHIATRIC RESEARCH. 2023;160:217-224

Epigenetic changes in the CYP2D6 gene are related to severity of suicide attempt: A cross-sectional study of suicide attempters.

Boström AED; Jamshidi E; Manu D-M; Kular L; Schiöth HB; Åsberg M; Jokinen J
Article: EPIGENETICS. 2022;17(11):1311-1330

DNA methylation changes in glial cells of the normal-appearing white matter in Multiple Sclerosis patients.

Kular L; Ewing E; Needhamsen M; Pahlevan Kakhki M; Covacu R; Gomez-Cabrero D; Brundin L; Jagodic M
Article: FRONTIERS IN AGING NEUROSCIENCE. 2022;14:926468

Epigenetic clock indicates accelerated aging in glial cells of progressive multiple sclerosis patients.

Kular L; Klose D; Urdánoz-Casado A; Ewing E; Planell N; Gomez-Cabrero D; Needhamsen M; Jagodic M
Article: MULTIPLE SCLEROSIS JOURNAL. 2021;27(7):1014-1026

Methylome and transcriptome signature of bronchoalveolar cells from multiple sclerosis patients in relation to smoking.

Ringh MV; Hagemann-Jensen M; Needhamsen M; Kullberg S; Wahlström J; Grunewald J; Brynedal B; Jagodic M; Ekström TJ; Öckinger J; Kular L
Article: EPIGENETICS. 2020;15(6-7):646-663

Longitudinal DNA methylation changes at MET may alter HGF/c-MET signalling in adolescents at risk for depression.

Ciuculete DM; Voisin S; Kular L; Welihinda N; Jonsson J; Jagodic M; Mwinyi J; Schiöth HB
Article: CLINICAL EPIGENETICS. 2020;12(1):99

meQTL and ncRNA functional analyses of 102 GWAS-SNPs associated with depression implicate HACE1 and SHANK2 genes.

Ciuculete DM; Voisin S; Kular L; Jonsson J; Rask-Andersen M; Mwinyi J; Schiöth HB
Article: JOURNAL OF CLINICAL INVESTIGATION. 2020;130(2):838-852

C-type lectin receptors Mcl and Mincle control development of multiple sclerosis-like neuroinflammation.

N'diaye M; Brauner S; Flytzani S; Kular L; Warnecke A; Adzemovic MZ; Piket E; Min J-H; Edwards W; Mela F; Choi HY; Magg V; James T; Linden M; Reichardt HM; Daws MR; van Horssen J; Kockum I; Harris RA; Olsson T; Guerreiro-Cacais AO; Jagodic M
Article: EBIOMEDICINE. 2019;46:290-304

Tobacco smoking induces changes in true DNA methylation, hydroxymethylation and gene expression in bronchoalveolar lavage cells.

Ringh MV; Hagemann-Jensen M; Needhamsen M; Kular L; Breeze CE; Sjöholm LK; Slavec L; Kullberg S; Wahlström J; Grunewald J; Brynedal B; Liu Y; Almgren M; Jagodic M; Öckinger J; Ekström TJ
Article: JOURNAL OF AUTOIMMUNITY. 2019;101:17-25

Small non-coding RNAs as important players, biomarkers and therapeutic targets in multiple sclerosis: A comprehensive overview.

Piket E; Zheleznyakova GY; Kular L; Jagodic M
Article: CLINICAL EPIGENETICS. 2019;11(1):86

Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis.

Kular L; Needhamsen M; Adzemovic MZ; Kramarova T; Gomez-Cabrero D; Ewing E; Piket E; Tegnér J; Beck S; Piehl F; Brundin L; Jagodic M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(19):9443-9452

Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migration.

Li D; Kular L; Vij M; Herter EK; Li X; Wang A; Chu T; Toma M-A; Zhang L; Liapi E; Mota A; Blomqvist L; Gallais Sérézal I; Rollman O; Wikstrom JD; Bienko M; Berglund D; Ståhle M; Sommar P; Jagodic M; Landén NX
Article: EBIOMEDICINE. 2019;43:411-423

Combining evidence from four immune cell types identifies DNA methylation patterns that implicate functionally distinct pathways during Multiple Sclerosis progression.

Ewing E; Kular L; Fernandes SJ; Karathanasis N; Lagani V; Ruhrmann S; Tsamardinos I; Tegner J; Piehl F; Gomez-Cabrero D; Jagodic M
Article: NATURE COMMUNICATIONS. 2018;9(1):4845

Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells.

Lund H; Pieber M; Parsa R; Han J; Grommisch D; Ewing E; Kular L; Needhamsen M; Espinosa A; Nilsson E; Överby AK; Butovsky O; Jagodic M; Zhang X-M; Harris RA
Article: MULTIPLE SCLEROSIS JOURNAL. 2018;24(10):1288-1300

Hypermethylation of MIR21 in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes.

Ruhrmann S; Ewing E; Piket E; Kular L; Cetrulo Lorenzi JC; Fernandes SJ; Morikawa H; Aeinehband S; Sayols-Baixeras S; Aslibekyan S; Absher DM; Arnett DK; Tegner J; Gomez-Cabrero D; Piehl F; Jagodic M
Article: JOURNAL OF PSYCHIATRIC RESEARCH. 2018;102:44-51

Changes in methylation within the STK32B promoter are associated with an increased risk for generalized anxiety disorder in adolescents.

Ciuculete DM; Boström AE; Tuunainen A-K; Sohrabi F; Kular L; Jagodic M; Voisin S; Mwinyi J; Schiöth HB
Article: NATURE COMMUNICATIONS. 2018;9(1):2397

DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis.

Kular L; Liu Y; Ruhrmann S; Zheleznyakova G; Marabita F; Gomez-Cabrero D; James T; Ewing E; Lindén M; Górnikiewicz B; Aeinehband S; Stridh P; Link J; Andlauer TFM; Gasperi C; Wiendl H; Zipp F; Gold R; Tackenberg B; Weber F; Hemmer B; Strauch K; Heilmann-Heimbach S; Rawal R; Schminke U; Schmidt CO; Kacprowski T; Franke A; Laudes M; Dilthey AT; Celius EG; Søndergaard HB; Tegnér J; Harbo HF; Oturai AB; Olafsson S; Eggertsson HP; Halldorsson BV; Hjaltason H; Olafsson E; Jonsdottir I; Stefansson K; Olsson T; Piehl F; Ekström TJ; Kockum I; Feinberg AP; Jagodic M
Article: NATURE IMMUNOLOGY. 2018;19(5):435-7

Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling.

Lund H; Pieber M; Parsa R; Grommisch D; Ewing E; Kular L; Han J; Zhu K; Nijssen J; Hedlund E; Needhamsen M; Ruhrmann S; Guerreiro-Cacais AO; Berglund R; Forteza MJ; Ketelhuth DFJ; Butovsky O; Jagodic M; Zhang X-M; Harris RA
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2018;138(4):882-892

Genome-Wide Screen for MicroRNAs Reveals a Role for miR-203 in Melanoma Metastasis.

Lohcharoenkal W; Das Mahapatra K; Pasquali L; Crudden C; Kular L; Akkaya Ulum YZ; Zhang L; Xu Landén N; Girnita L; Jagodic M; Ståhle M; Sonkoly E; Pivarcsi A
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(6):479-485

Decreased Expression of IFNG-AS1, IFNG and IL-1B Inflammatory Genes in Medicated Schizophrenia and Bipolar Patients.

Ghafelehbashi H; Pahlevan Kakhki M; Kular L; Moghbelinejad S; Ghafelehbashi SH
Article: BMC BIOINFORMATICS. 2017;18(1):486

Usability of human Infinium MethylationEPIC BeadChip for mouse DNA methylation studies.

Needhamsen M; Ewing E; Lund H; Gomez-Cabrero D; Harris RA; Kular L; Jagodic M
Article: SCIENTIFIC REPORTS. 2017;7(1):14589

Smoking induces DNA methylation changes in Multiple Sclerosis patients with exposure-response relationship.

Marabita F; Almgren M; Sjöholm LK; Kular L; Liu Y; James T; Kiss NB; Feinberg AP; Olsson T; Kockum I; Alfredsson L; Ekström TJ; Jagodic M
Article: JOURNAL OF IMMUNOLOGY. 2013;190(8):4066-4075

Next-generation sequencing identifies microRNAs that associate with pathogenic autoimmune neuroinflammation in rats.

Bergman P; James T; Kular L; Ruhrmann S; Kramarova T; Kvist A; Supic G; Gillett A; Pivarcsi A; Jagodic M
Article: JOURNAL OF NEUROINFLAMMATION. 2012;9:36

NOV/CCN3 attenuates inflammatory pain through regulation of matrix metalloproteinases-2 and -9.

Kular L; Rivat C; Lelongt B; Calmel C; Laurent M; Pohl M; Kitabgi P; Melik-Parsadaniantz S; Martinerie C
Article: GLIA. 2010;58(12):1510-1521

NOV/CCN3 upregulates CCL2 and CXCL1 expression in astrocytes through beta1 and beta5 integrins.

Le Dréau G; Kular L; Nicot AB; Calmel C; Melik-Parsadaniantz S; Kitabgi P; Laurent M; Martinerie C
Visa fler

Alla övriga publikationer

Review: JOURNAL OF INTERNAL MEDICINE. 2020;288(1):82-102

Epigenetic insights into multiple sclerosis disease progression.

Kular L; Jagodic M
Review: EVOLUTION PSYCHIATRIQUE. 2019;84(1):207-221

Epigenetics as a partner of psychiatry: Toward a personalized approach of the patient

Kular S; Kular L
Review: PSYCHIATRY AND CLINICAL NEUROSCIENCES. 2018;72(4):195-211

Epigenetics applied to psychiatry: Clinical opportunities and future challenges.

Kular L; Kular S
Corrigendum: SCIENTIFIC REPORTS. 2018;8(1):4340

Author Correction: Smoking induces DNA methylation changes in Multiple Sclerosis patients with exposure-response relationship.

Marabita F; Almgren M; Sjöholm LK; Kular L; Liu Y; James T; Kiss NB; Feinberg AP; Olsson T; Kockum I; Alfredsson L; Ekström TJ; Jagodic M
Review: PHYSIOLOGICAL GENOMICS. 2017;49(9):447-461

Epigenetic research in multiple sclerosis: progress, challenges, and opportunities.

Zheleznyakova GY; Piket E; Marabita F; Pahlevan Kakhki M; Ewing E; Ruhrmann S; Needhamsen M; Jagodic M; Kular L
Review: INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. 2015;67:49-57

Genomic imprinting: A missing piece of the Multiple Sclerosis puzzle?

Ruhrmann S; Stridh P; Kular L; Jagodic M
Review: BIOCHIMIE. 2011;93(3):377-388

The CCN family: a new class of inflammation modulators?

Kular L; Pakradouni J; Kitabgi P; Laurent M; Martinerie C
Review: FRONTIERS IN NEUROENDOCRINOLOGY. 2011;32(1):10-24

Chemokines and chemokine receptors: new actors in neuroendocrine regulations.

Rostène W; Guyon A; Kular L; Godefroy D; Barbieri F; Bajetto A; Banisadr G; Callewaere C; Conductier G; Rovère C; Mélik-Parsadaniantz S; Florio T

Om mig

Artiklar

Alla övriga publikationer

Nyheter från KI

Kalenderhändelser från KI