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Lars Ketscher

Postdoc

Länkar

Publikationer

ISG15 uncut: Dissecting enzymatic and non-enzymatic functions of USP18 in vivo
Ketscher L, Knobeloch Kp
CYTOKINE 2015;76(2):569-71

Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistance
Ketscher L, Hannss R, Morales Dj, Basters A, Guerra S, Goldmann T, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2015;112(5):1577-82

USP18 lack in microglia causes destructive interferonopathy of the mouse brain
Goldmann T, Zeller N, Raasch J, Kierdorf K, Frenzel K, Ketscher L, et al
EMBO JOURNAL 2015;34(12):1612-29

Molecular characterization of ubiquitin-specific protease 18 reveals substrate specificity for interferon-stimulated gene 15
Basters A, Geurink Pp, El Oualid F, Ketscher L, Casutt Ms, Krause E, et al
FEBS JOURNAL 2014;281(7):1918-28

Ubiquitin-Like Protein ISG15 (Interferon-Stimulated Gene of 15 kDa) in Host Defense Against Heart Failure in a Mouse Model of Virus-Induced Cardiomyopathy
Rahnefeld A, Klingel K, Schuermann A, Diny Nl, Althof N, Lindner A, et al
CIRCULATION 2014;130(18):1589-600

High yield expression of catalytically active USP18 (UBP43) using a Trigger Factor fusion system
Basters A, Ketscher L, Deuerling E, Arkona C, Rademann J, Knobeloch Kp, et al
BMC BIOTECHNOLOGY 2012;:56-

mHERC6 is the essential ISG15 E3 ligase in the murine system
Ketscher L, Basters A, Prinz M, Knobeloch Kp
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2012;417(1):135-40

A one-day, dispense-only IP-one HTRF assay for high-throughput screening of G(alpha q) protein-coupled receptors: Towards cells as reagents
Bergsdorf C, Kropp-goerkis C, Kaehler I, Ketscher L, Boemer U, Parczyk K, et al
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES 2008;6(1):39-53

Phospholipase A(2) inhibition at different substrate concentrations
Bohl M, Ketscher L, Tietbohl C, Gutzeit Ho
ANALYTICAL BIOCHEMISTRY 2006;359(2):280-2