Karine Chemin

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: EMBO MOLECULAR MEDICINE. 2023;15(10):e17240

Single-cell profiling of muscle-infiltrating T cells in idiopathic inflammatory myopathies.

Argyriou A; Horuluoglu B; Galindo-Feria AS; Diaz-Boada JS; Sijbranda M; Notarnicola A; Dani L; van Vollenhoven A; Ramsköld D; Nennesmo I; Dastmalchi M; Lundberg IE; Diaz-Gallo L-M; Chemin K
Article: CLINICAL RHEUMATOLOGY. 2023;42(10):2889-2895

Occurrence and localization of FOXP3 + cells in kidney biopsies in lupus nephritis and ANCA-associated vasculitis.

Zickert A; Janković MR; Malmström V; Chemin K; Gunnarsson I
Article: RHEUMATOLOGY. 2023;:kead400

Autoantibodies against the melanoma differentiation-associated protein 5 in patients with dermatomyositis target the helicase domains.

Van Gompel E; Demirdal D; Fernandes-Cerqueira C; Horuluoglu B; Galindo-Feria A; Wigren E; Gräslund S; De Langhe E; Benveniste O; Notarnicola A; Chemin K; Lundberg IE
Article: ARTHRITIS & RHEUMATOLOGY. 2023;75(5):673-684

Diversity and Clonality of T Cell Receptor Repertoire and Antigen Specificities in Small Joints of Early Rheumatoid Arthritis.

Turcinov S; Af Klint E; Van Schoubroeck B; Kouwenhoven A; Mia S; Chemin K; Wils H; Van Hove C; De Bondt A; Keustermans K; Van Houdt J; Reumers J; Felix N; Rao NL; Peeters P; Stevenaert F; Klareskog L; McKinnon M; Baker D; Suri A; Malmström V
Article: KIDNEY INTERNATIONAL. 2023;103(5):973-985

Identification of proteinase 3 autoreactive CD4+T cells and their T-cell receptor repertoires in antineutrophil cytoplasmic antibody-associated vasculitis.

Sharma RK; Yoosuf N; Afonso M; Scheffschick A; Avik A; Bartoletti A; Horuluoglu B; Diaz Boada JS; Boddul SK; Jonasdottir AD; Lövström B; Brauner H; Raposo B; Chemin K; Bruchfeld A; Gunnarsson I; Malmström V
Article: SCIENTIFIC REPORTS. 2022;12(1):11876

Integrated single cell and spatial transcriptomics reveal autoreactive differentiated B cells in joints of early rheumatoid arthritis.

Hardt U; Carlberg K; Af Klint E; Sahlström P; Larsson L; van Vollenhoven A; Hernandez Machado S; Israelsson L; Amara K; Chemin K; Korotkova M; Karlsson Hedestam GB; Catrina AI; Teichmann SA; Ståhl PL; Malmström V
Article: NATURE COMMUNICATIONS. 2022;13(1):4046

Single cell sequencing identifies clonally expanded synovial CD4+ TPH cells expressing GPR56 in rheumatoid arthritis.

Argyriou A; Wadsworth MH; Lendvai A; Christensen SM; Hensvold AH; Gerstner C; van Vollenhoven A; Kravarik K; Winkler A; Malmström V; Chemin K
Article: JOURNAL OF AUTOIMMUNITY. 2022;131:102857

Modulating T-cell activation with antisense oligonucleotides targeting lymphocyte cytosolic protein 2.

Iyer VS; Boddul SV; Johnsson A-K; Raposo B; Sharma RK; Shen Y; Kasza Z; Lim KW; Chemin K; Nilsson G; Malmström V; Phan AT; Wermeling F
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:826152

Rituximab in Systemic Lupus Erythematosus: Transient Effects on Autoimmunity Associated Lymphocyte Phenotypes and Implications for Immunogenicity.

Faustini F; Sippl N; Stålesen R; Chemin K; Dunn N; Fogdell-Hahn A; Gunnarsson I; Malmström V
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2021;205(1):44-52

Arthritis in systemic lupus erythematosus is characterized by local IL-17A and IL-6 expression in synovial fluid.

Sippl N; Faustini F; Rönnelid J; Turcinov S; Chemin K; Gunnarsson I; Malmström V
Article: ANNALS OF THE RHEUMATIC DISEASES. 2021;80(2):194-202

Natural killer cells and type II interferon in Ro/SSA and La/SSB autoantibody-exposed newborns at risk of congenital heart block.

Ivanchenko M; Thorlacius GE; Hedlund M; Ottosson V; Meneghel L; Björkander S; Ossoinak A; Tingström J; Bremme K; Sverremark-Ekström E; Gemzell-Danielsson K; Sonesson S-E; Chemin K; Wahren-Herlenius M
Article: BMC IMMUNOLOGY. 2020;21(1):27

Multi-HLA class II tetramer analyses of citrulline-reactive T cells and early treatment response in rheumatoid arthritis.

Gerstner C; Turcinov S; Hensvold AH; Chemin K; Uchtenhagen H; Ramwadhdoebe TH; Dubnovitsky A; Kozhukh G; Rönnblom L; Kwok WW; Achour A; Catrina AI; van Baarsen LGM; Malmström V
Article: ANNALS OF THE RHEUMATIC DISEASES. 2018;77(10):1454-1462

Systematic approach demonstrates enrichment of multiple interactions between non-HLA risk variants and HLA-DRB1 risk alleles in rheumatoid arthritis.

Diaz-Gallo L-M; Ramsköld D; Shchetynsky K; Folkersen L; Chemin K; Brynedal B; Uebe S; Okada Y; Alfredsson L; Klareskog L; Padyukov L
Article: ARTHRITIS RESEARCH & THERAPY. 2018;20(1):188

T-cell transcriptomics from peripheral blood highlights differences between polymyositis and dermatomyositis patients.

Houtman M; Ekholm L; Hesselberg E; Chemin K; Malmström V; Reed AM; Lundberg IE; Padyukov L
Article: JOURNAL OF AUTOIMMUNITY. 2018;90:28-38

T cells are influenced by a long non-coding RNA in the autoimmune associated PTPN2 locus.

Houtman M; Shchetynsky K; Chemin K; Hensvold AH; Ramsköld D; Tandre K; Eloranta M-L; Rönnblom L; Uebe S; Catrina AI; Malmström V; Padyukov L
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2018;192(3):259-270

Diminished CXCR5 expression in peripheral blood of patients with Sjögren's syndrome may relate to both genotype and salivary gland homing.

Aqrawi LA; Ivanchenko M; Björk A; Ramírez Sepúlveda JI; Imgenberg-Kreuz J; Kvarnström M; Haselmayer P; Jensen JL; Nordmark G; Chemin K; Skarstein K; Wahren-Herlenius M
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2018;48(4):655-669

EOMES-positive CD4+ T cells are increased in PTPN22 (1858T) risk allele carriers.

Chemin K; Ramsköld D; Diaz-Gallo L-M; Herrath J; Houtman M; Tandre K; Rönnblom L; Catrina A; Malmström V
Article: FRONTIERS IN IMMUNOLOGY. 2018;9:3033

Differential ACPA Binding to Nuclear Antigens Reveals a PAD-Independent Pathway and a Distinct Subset of Acetylation Cross-Reactive Autoantibodies in Rheumatoid Arthritis.

Lloyd KA; Wigerblad G; Sahlström P; Garimella MG; Chemin K; Steen J; Titcombe PJ; Marklein B; Zhou D; Stålesen R; Ossipova E; Lundqvist C; Ekwall O; Rönnelid J; Mueller DL; Karlsson MCI; Kaplan MJ; Skriner K; Klareskog L; Wermeling F; Malmström V; Grönwall C
Article: ARTHRITIS & RHEUMATOLOGY. 2016;68(5):1124-1135

A Novel HLA-DRB1*10:01-Restricted T Cell Epitope From Citrullinated Type II Collagen Relevant to Rheumatoid Arthritis.

Chemin K; Pollastro S; James E; Ge C; Albrecht I; Herrath J; Gerstner C; Tandre K; Sampaio Rizzi T; Rönnblom L; Catrina A; Holmdahl R; Klareskog L; de Vries N; Malmström V
Article: JOURNAL OF CLINICAL INVESTIGATION. 2015;125(12):4612-4624

Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies.

Albrecht I; Wick C; Hallgren Å; Tjärnlund A; Nagaraju K; Andrade F; Thompson K; Coley W; Phadke A; Diaz-Gallo L-M; Bottai M; Nennesmo I; Chemin K; Herrath J; Johansson K; Wikberg A; Ytterberg AJ; Zubarev RA; Danielsson O; Krystufkova O; Vencovsky J; Landegren N; Wahren-Herlenius M; Padyukov L; Kämpe O; Lundberg IE
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2014;44(10):2979-2989

Surface expression of CD39 identifies an enriched Treg-cell subset in the rheumatic joint, which does not suppress IL-17A secretion.

Herrath J; Chemin K; Albrecht I; Catrina AI; Malmström V
Article: NATURE IMMUNOLOGY. 2013;14(7):723-731

VAMP7 controls T cell activation by regulating the recruitment and phosphorylation of vesicular Lat at TCR-activation sites.

Larghi P; Williamson DJ; Carpier J-M; Dogniaux S; Chemin K; Bohineust A; Danglot L; Gaus K; Galli T; Hivroz C
Article: JOURNAL OF IMMUNOLOGY. 2012;189(5):2159-2168

Cytokine secretion by CD4+ T cells at the immunological synapse requires Cdc42-dependent local actin remodeling but not microtubule organizing center polarity.

Chemin K; Bohineust A; Dogniaux S; Tourret M; Guégan S; Miro F; Hivroz C
Article: BLOOD. 2012;119(18):4174-4181

The Ets-1 transcription factor is required for Stat1-mediated T-bet expression and IgG2a class switching in mouse B cells.

Nguyen HV; Mouly E; Chemin K; Luinaud R; Despres R; Fermand J-P; Arnulf B; Bories J-C
Article: CRITICAL REVIEWS IN IMMUNOLOGY. 2012;32(2):139-155

Crosstalk between T lymphocytes and dendritic cells.

Hivroz C; Chemin K; Tourret M; Bohineust A
Article: PLOS ONE. 2011;6(5):e19680

Force generation upon T cell receptor engagement.

Husson J; Chemin K; Bohineust A; Hivroz C; Henry N
Article: JOURNAL OF IMMUNOLOGY. 2010;185(11):6809-6818

T cell polarity at the immunological synapse is required for CD154-dependent IL-12 secretion by dendritic cells.

Tourret M; Guégan S; Chemin K; Dogniaux S; Miro F; Bohineust A; Hivroz C
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2010;207(10):2113-2125

The Ets-1 transcription factor controls the development and function of natural regulatory T cells.

Mouly E; Chemin K; Nguyen HV; Chopin M; Mesnard L; Leite-de-Moraes M; Burlen-defranoux O; Bandeira A; Bories J-C
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2009;39(7):1966-1976

Hypomorphic mutation of ZAP70 in human results in a late onset immunodeficiency and no autoimmunity.

Picard C; Dogniaux S; Chemin K; Maciorowski Z; Lim A; Mazerolles F; Rieux-Laucat F; Stolzenberg M-C; Debre M; Magny J-P; Le Deist F; Fischer A; Hivroz C
Article: BLOOD. 2008;111(7):3579-3590

Cognate CD4+ T-cell-dendritic cell interactions induce migration of immature dendritic cells through dissolution of their podosomes.

Nobile C; Lind M; Miro F; Chemin K; Tourret M; Occhipinti G; Dogniaux S; Amigorena S; Hivroz C
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2007;136(4):609-614

Detection and follow-up of fibroblast growth factor receptor 3 expression on bone marrow and circulating plasma cells by flow cytometry in patients with t(4;14) multiple myeloma.

Chandesris MO; Soulier J; Labaume S; Crinquette A; Repellini L; Chemin K; Malphettes M; Fieschi C; Asli B; Uzunhan Y; Fermand JP; Bories JC; Arnulf B
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(44):15712-15717

The Ets-1 transcription factor is required for complete pre-T cell receptor function and allelic exclusion at the T cell receptor beta locus.

Eyquem S; Chemin K; Fasseu M; Bories J-C
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2004;34(11):3187-3196

The development of early and mature B cells is impaired in mice deficient for the Ets-1 transcription factor.

Eyquem S; Chemin K; Fasseu M; Chopin M; Sigaux F; Cumano A; Bories J-C
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Editorial comment: NATURE REVIEWS RHEUMATOLOGY. 2023;19(5):259-260

Citrulline immunity in RA: CD8+ T cells enter the scene.

Chemin K; Malmström V
Letter: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2019;195(3):305-309

FoxP3+ CXCR5+ CD4+ T cell frequencies are increased in peripheral blood of patients with primary Sjögren's syndrome.

Ivanchenko M; Aqrawi LA; Björk A; Wahren-Herlenius M; Chemin K
Review: FRONTIERS IN IMMUNOLOGY. 2019;10:353

Effector Functions of CD4+ T Cells at the Site of Local Autoimmune Inflammation-Lessons From Rheumatoid Arthritis.

Chemin K; Gerstner C; Malmström V
Letter: ARTHRITIS & RHEUMATOLOGY. 2016;68(8):2053-2054

Reply.

Chemin K; Albrecht I; Pollastro S; de Vries N; Holmdahl R; Malmström V
Review: CURRENT OPINION IN RHEUMATOLOGY. 2016;28(2):181-188

Is rheumatoid arthritis an autoimmune disease?

Chemin K; Klareskog L; Malmström V
Review: SEMINARS IN IMMUNOPATHOLOGY. 2010;32(2):107-116

ZAP70: a master regulator of adaptive immunity.

Fischer A; Picard C; Chemin K; Dogniaux S; le Deist F; Hivroz C

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