Jakob Michaelsson

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Jag är forskargruppsledare för Jakob Michaelssonäs research group
[1] på Centrum för Infektionsmedicin, CIM vid Institutionen för medicin
Huddinge.
[1] https://ki.se/en/medh/jakob-michaelsson-group

Artiklar

Article: RESPIRATORY RESEARCH. 2023;24(1):62

Targeted plasma proteomics reveals signatures discriminating COVID-19 from sepsis with pneumonia.

Palma Medina LM; Babačić H; Dzidic M; Parke Å; Garcia M; Maleki KT; Unge C; Lourda M; Kvedaraite E; Chen P; Muvva JR; Cornillet M; Emgård J; Moll K; Karolinska K. I./K. COVID-19 Study Group; Michaëlsson J; Flodström-Tullberg M; Brighenti S; Buggert M; Mjösberg J; Malmberg K-J; Sandberg JK; Gredmark-Russ S; Rooyackers O; Svensson M; Chambers BJ; Eriksson LI; Pernemalm M; Björkström NK; Aleman S; Ljunggren H-G; Klingström J; Strålin K; Norrby-Teglund A
Article: NATURE CELL BIOLOGY. 2023;25(2):351-365

A topographic atlas defines developmental origins of cell heterogeneity in the human embryonic lung.

Sountoulidis A; Marco Salas S; Braun E; Avenel C; Bergenstråhle J; Theelke J; Vicari M; Czarnewski P; Liontos A; Abalo X; Andrusivová Ž; Mirzazadeh R; Asp M; Li X; Hu L; Sariyar S; Martinez Casals A; Ayoglu B; Firsova A; Michaëlsson J; Lundberg E; Wählby C; Sundström E; Linnarsson S; Lundeberg J; Nilsson M; Samakovlis C
Article: CELL REPORTS. 2022;38(10):110503

SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells.

Hammer Q; Dunst J; Christ W; Picarazzi F; Wendorff M; Momayyezi P; Huhn O; Netskar HK; Maleki KT; García M; Sekine T; Sohlberg E; Azzimato V; Aouadi M; Karolinska COVID-19 Study Group; Severe COVID-19 GWAS Group; Degenhardt F; Franke A; Spallotta F; Mori M; Michaëlsson J; Björkström NK; Rückert T; Romagnani C; Horowitz A; Klingström J; Ljunggren H-G; Malmberg K-J
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:834862

Comparison of Lung-Homing Receptor Expression and Activation Profiles on NK Cell and T Cell Subsets in COVID-19 and Influenza.

Brownlie D; Rødahl I; Varnaite R; Asgeirsson H; Glans H; Falck-Jones S; Vangeti S; Buggert M; Ljunggren H-G; Michaëlsson J; Gredmark-Russ S; Smed-Sörensen A; Marquardt N
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(40):e2109123118

High-dimensional profiling reveals phenotypic heterogeneity and disease-specific alterations of granulocytes in COVID-19.

Lourda M; Dzidic M; Hertwig L; Bergsten H; Palma Medina LM; Sinha I; Kvedaraite E; Chen P; Muvva JR; Gorin J-B; Cornillet M; Emgård J; Moll K; García M; Maleki KT; Klingström J; Michaëlsson J; Flodström-Tullberg M; Brighenti S; Buggert M; Mjösberg J; Malmberg K-J; Sandberg JK; Henter J-I; Folkesson E; Gredmark-Russ S; Sönnerborg A; Eriksson LI; Rooyackers O; Aleman S; Strålin K; Ljunggren H-G; Björkström NK; Svensson M; Ponzetta A; Norrby-Teglund A; Chambers BJ; Karolinska KI/K COVID-19 Study Group
Article: CELLS. 2021;10(7):1713

In Vitro Study of Human Immune Responses to Hyaluronic Acid Hydrogels, Recombinant Spidroins and Human Neural Progenitor Cells of Relevance to Spinal Cord Injury Repair.

Lin C; Ekblad-Nordberg Å; Michaëlsson J; Götherström C; Hsu C-C; Ye H; Johansson J; Rising A; Sundström E; Åkesson E
Article: SCIENCE TRANSLATIONAL MEDICINE. 2021;13(599):eabb3107

A biliary immune landscape map of primary sclerosing cholangitis reveals a dominant network of neutrophils and tissue-resident T cells.

Zimmer CL; von Seth E; Buggert M; Strauss O; Hertwig L; Nguyen S; Wong AYW; Zotter C; Berglin L; Michaëlsson J; Hansson MR; Arnelo U; Sparrelid E; Ellis ECS; Söderholm JD; Keita ÅV; Holm K; Özenci V; Hov JR; Mold JE; Cornillet M; Ponzetta A; Bergquist A; Björkström NK
Article: CELL REPORTS. 2021;35(8):109174

Divergent clonal differentiation trajectories establish CD8+ memory T cell heterogeneity during acute viral infections in humans.

Mold JE; Modolo L; Hård J; Zamboni M; Larsson AJM; Stenudd M; Eriksson C-J; Durif G; Ståhl PL; Borgström E; Picelli S; Reinius B; Sandberg R; Réu P; Talavera-Lopez C; Andersson B; Blom K; Sandberg JK; Picard F; Michaëlsson J; Frisén J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(11):e2016580118

Expansions of adaptive-like NK cells with a tissue-resident phenotype in human lung and blood.

Brownlie D; Scharenberg M; Mold JE; Hård J; Kekäläinen E; Buggert M; Nguyen S; Wilson JN; Al-Ameri M; Ljunggren H-G; Marquardt N; Michaëlsson J
Article: IMMUNITY. 2021;54(2):259-275.e7

Distinct developmental pathways from blood monocytes generate human lung macrophage diversity.

Evren E; Ringqvist E; Tripathi KP; Sleiers N; Rives IC; Alisjahbana A; Gao Y; Sarhan D; Halle T; Sorini C; Lepzien R; Marquardt N; Michaëlsson J; Smed-Sörensen A; Botling J; Karlsson MCI; Villablanca EJ; Willinger T
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:752104

CD5 Surface Expression Marks Intravascular Human Innate Lymphoid Cells That Have a Distinct Ontogeny and Migrate to the Lung.

Alisjahbana A; Gao Y; Sleiers N; Evren E; Brownlie D; von Kries A; Jorns C; Marquardt N; Michaëlsson J; Willinger T
Article: SCIENCE IMMUNOLOGY. 2020;5(50):eabd6832

Natural killer cell immunotypes related to COVID-19 disease severity.

Maucourant C; Filipovic I; Ponzetta A; Aleman S; Cornillet M; Hertwig L; Strunz B; Lentini A; Reinius B; Brownlie D; Cuapio A; Ask EH; Hull RM; Haroun-Izquierdo A; Schaffer M; Klingström J; Folkesson E; Buggert M; Sandberg JK; Eriksson LI; Rooyackers O; Ljunggren H-G; Malmberg K-J; Michaëlsson J; Marquardt N; Hammer Q; Strålin K; Björkström NK; Karolinska COVID-19 Study Group
Article: PLOS BIOLOGY. 2019;17(10):e3000383

Cell generation dynamics underlying naive T-cell homeostasis in adult humans.

Mold JE; Réu P; Olin A; Bernard S; Michaëlsson J; Rane S; Yates A; Khosravi A; Salehpour M; Possnert G; Brodin P; Frisén J
Article: NATURE COMMUNICATIONS. 2019;10(1):3841

Unique transcriptional and protein-expression signature in human lung tissue-resident NK cells.

Marquardt N; Kekäläinen E; Chen P; Lourda M; Wilson JN; Scharenberg M; Bergman P; Al-Ameri M; Hård J; Mold JE; Ljunggren H-G; Michaëlsson J
Article: GENOME BIOLOGY. 2019;20(1):68

Conbase: a software for unsupervised discovery of clonal somatic mutations in single cells through read phasing.

Hård J; Al Hakim E; Kindblom M; Björklund ÅK; Sennblad B; Demirci I; Paterlini M; Reu P; Borgström E; Ståhl PL; Michaelsson J; Mold JE; Frisén J
Article: JOURNAL OF CROHNS & COLITIS. 2019;13(1):67-78

Distinct Alterations in the Composition of Mucosal Innate Lymphoid Cells in Newly Diagnosed and Established Crohn's Disease and Ulcerative Colitis.

Forkel M; van Tol S; Höög C; Michaëlsson J; Almer S; Mjösberg J
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:1116

Influenza A Virus Infection Induces Hyperresponsiveness in Human Lung Tissue-Resident and Peripheral Blood NK Cells.

Scharenberg M; Vangeti S; Kekäläinen E; Bergman P; Al-Ameri M; Johansson N; Sondén K; Falck-Jones S; Färnert A; Ljunggren H-G; Michaëlsson J; Smed-Sörensen A; Marquardt N
Article: IMMUNOHORIZONS. 2018;2(6):172-184

Breadth and Dynamics of HLA-A2- and HLA-B7-Restricted CD8+ T Cell Responses against Nonstructural Viral Proteins in Acute Human Tick-Borne Encephalitis Virus Infection.

Lampen MH; Uchtenhagen H; Blom K; Varnaitė R; Pakalniene J; Dailidyte L; Wälchli S; Lindquist L; Mickiene A; Michaëlsson J; Schumacher TN; Ljunggren H-G; Sandberg JK; Achour A; Gredmark-Russ S
Article: BIOINFORMATICS. 2018;34(3):485-493

High dimensional classification with combined adaptive sparse PLS and logistic regression.

Durif G; Modolo L; Michaelsson J; Mold JE; Lambert-Lacroix S; Picard F
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2017;47(8):1280-1294

Composition and functionality of the intrahepatic innate lymphoid cell-compartment in human nonfibrotic and fibrotic livers.

Forkel M; Berglin L; Kekäläinen E; Carlsson A; Svedin E; Michaëlsson J; Nagasawa M; Erjefält JS; Mori M; Flodström-Tullberg M; Bergquist A; Ljunggren H-G; Westgren M; Lindforss U; Friberg D; Jorns C; Ellis E; Björkström NK; Mjösberg J
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;139(4):1321-1330.e4

Human lung natural killer cells are predominantly comprised of highly differentiated hypofunctional CD69-CD56dim cells.

Marquardt N; Kekäläinen E; Chen P; Kvedaraite E; Wilson JN; Ivarsson MA; Mjösberg J; Berglin L; Säfholm J; Manson ML; Adner M; Al-Ameri M; Bergman P; Orre A-C; Svensson M; Dahlén B; Dahlén S-E; Ljunggren H-G; Michaëlsson J
Article: IMMUNITY. 2017;46(2):287-300

CD49a Expression Defines Tissue-Resident CD8+ T Cells Poised for Cytotoxic Function in Human Skin.

Cheuk S; Schlums H; Gallais Sérézal I; Martini E; Chiang SC; Marquardt N; Gibbs A; Detlofsson E; Introini A; Forkel M; Höög C; Tjernlund A; Michaëlsson J; Folkersen L; Mjösberg J; Blomqvist L; Ehrström M; Ståhle M; Bryceson YT; Eidsmo L
Article: NATURE GENETICS. 2016;48(11):1430-1435

Analysis of allelic expression patterns in clonal somatic cells by single-cell RNA-seq.

Reinius B; Mold JE; Ramsköld D; Deng Q; Johnsson P; Michaëlsson J; Frisén J; Sandberg R
Article: JOURNAL OF IMMUNOLOGY. 2016;197(8):3069-3075

Fetal CD103+ IL-17-Producing Group 3 Innate Lymphoid Cells Represent the Dominant Lymphocyte Subset in Human Amniotic Fluid.

Marquardt N; Ivarsson MA; Sundström E; Åkesson E; Martini E; Eidsmo L; Mjösberg J; Friberg D; Kublickas M; Ek S; Tegerstedt G; Seiger Å; Westgren M; Michaëlsson J
Article: JOURNAL OF IMMUNOLOGY. 2016;197(7):2762-2771

NK Cell Responses to Human Tick-Borne Encephalitis Virus Infection.

Blom K; Braun M; Pakalniene J; Lunemann S; Enqvist M; Dailidyte L; Schaffer M; Lindquist L; Mickiene A; Michaëlsson J; Ljunggren H-G; Gredmark-Russ S
Article: JOURNAL OF IMMUNOLOGY. 2015;195(7):3262-3272

The Human NK Cell Response to Yellow Fever Virus 17D Is Primarily Governed by NK Cell Differentiation Independently of NK Cell Education.

Marquardt N; Ivarsson MA; Blom K; Gonzalez VD; Braun M; Falconer K; Gustafsson R; Fogdell-Hahn A; Sandberg JK; Michaëlsson J
Article: IMMUNITY. 2015;43(2):394-407

Identification of a Human Natural Killer Cell Lineage-Restricted Progenitor in Fetal and Adult Tissues.

Renoux VM; Zriwil A; Peitzsch C; Michaëlsson J; Friberg D; Soneji S; Sitnicka E
Article: JOURNAL OF IMMUNOLOGY. 2015;194(6):2467-2471

Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells.

Marquardt N; Béziat V; Nyström S; Hengst J; Ivarsson MA; Kekäläinen E; Johansson H; Mjösberg J; Westgren M; Lankisch TO; Wedemeyer H; Ellis EC; Ljunggren H-G; Michaëlsson J; Björkström NK
Article: PLOS PATHOGENS. 2015;11(1):e1004622

Specificity and dynamics of effector and memory CD8 T cell responses in human tick-borne encephalitis virus infection.

Blom K; Braun M; Pakalniene J; Dailidyte L; Béziat V; Lampen MH; Klingström J; Lagerqvist N; Kjerstadius T; Michaëlsson J; Lindquist L; Ljunggren H-G; Sandberg JK; Mickiene A; Gredmark-Russ S
Article: MUCOSAL IMMUNOLOGY. 2014;7(5):1233-1243

Invariant natural killer T cells developing in the human fetus accumulate and mature in the small intestine.

Loh L; Ivarsson MA; Michaëlsson J; Sandberg JK; Nixon DF
Article: PLOS PATHOGENS. 2014;10(7):e1004251

T-bet and Eomes are differentially linked to the exhausted phenotype of CD8+ T cells in HIV infection.

Buggert M; Tauriainen J; Yamamoto T; Frederiksen J; Ivarsson MA; Michaëlsson J; Lund O; Hejdeman B; Jansson M; Sönnerborg A; Koup RA; Betts MR; Karlsson AC
Article: JOURNAL OF CLINICAL INVESTIGATION. 2013;123(9):3889-3901

Differentiation and functional regulation of human fetal NK cells.

Ivarsson MA; Loh L; Marquardt N; Kekäläinen E; Berglin L; Björkström NK; Westgren M; Nixon DF; Michaëlsson J
Article: BLOOD. 2013;121(14):2678-2688

NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs.

Béziat V; Liu LL; Malmberg J-A; Ivarsson MA; Sohlberg E; Björklund AT; Retière C; Sverremark-Ekström E; Traherne J; Ljungman P; Schaffer M; Price DA; Trowsdale J; Michaëlsson J; Ljunggren H-G; Malmberg K-J
Article: JOURNAL OF IMMUNOLOGY. 2013;190(5):2150-2158

Temporal dynamics of the primary human T cell response to yellow fever virus 17D as it matures from an effector- to a memory-type response.

Blom K; Braun M; Ivarsson MA; Gonzalez VD; Falconer K; Moll M; Ljunggren H-G; Michaëlsson J; Sandberg JK
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2011;41(8):2279-2290

The inflammatory milieu in the rheumatic joint reduces regulatory T-cell function.

Herrath J; Müller M; Amoudruz P; Janson P; Michaëlsson J; Larsson PT; Trollmo C; Raghavan S; Malmström V
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2011;73(2):141-146

NK cells and CD1d-restricted NKT cells respond in different ways with divergent kinetics to IL-2 treatment in primary HIV-1 infection.

Kuylenstierna C; Snyder-Cappione JE; Loo CP; Long BR; Gonzalez VD; Michaëlsson J; Moll M; Spotts G; Hecht FM; Nixon DF; Sandberg JK
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2011;208(1):13-21

Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus.

Björkström NK; Lindgren T; Stoltz M; Fauriat C; Braun M; Evander M; Michaëlsson J; Malmberg K-J; Klingström J; Ahlm C; Ljunggren H-G
Article: SCIENCE. 2010;330(6011):1695-1699

Fetal and adult hematopoietic stem cells give rise to distinct T cell lineages in humans.

Mold JE; Venkatasubrahmanyam S; Burt TD; Michaëlsson J; Rivera JM; Galkina SA; Weinberg K; Stoddart CA; McCune JM
Article: BLOOD. 2010;116(19):3853-3864

Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education.

Björkström NK; Riese P; Heuts F; Andersson S; Fauriat C; Ivarsson MA; Björklund AT; Flodström-Tullberg M; Michaëlsson J; Rottenberg ME; Guzmán CA; Ljunggren H-G; Malmberg K-J
Article: BLOOD. 2010;115(6):1166-1174

Education of human natural killer cells by activating killer cell immunoglobulin-like receptors.

Fauriat C; Ivarsson MA; Ljunggren H-G; Malmberg K-J; Michaëlsson J
Article: BLOOD. 2009;114(23):4823-4831

Functionally distinct subsets of human NK cells and monocyte/DC-like cells identified by coexpression of CD56, CD7, and CD4.

Milush JM; Long BR; Snyder-Cappione JE; Cappione AJ; York VA; Ndhlovu LC; Lanier LL; Michaëlsson J; Nixon DF
Article: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2009;25(6):603-605

HIV-1-specific T Cell-dependent natural killer (NK) cell activation: major contribution by NK cells to interferon-gamma production in response to HIV-1 antigens.

Loo CP; Long BR; Hecht FM; Nixon DF; Michaëlsson J
Article: SCIENCE. 2008;322(5907):1562-1565

Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero.

Mold JE; Michaëlsson J; Burt TD; Muench MO; Beckerman KP; Busch MP; Lee T-H; Nixon DF; McCune JM
Article: JOURNAL OF IMMUNOLOGY. 2008;181(9):6010-6019

Estimation of the size of the alloreactive NK cell repertoire: studies in individuals homozygous for the group A KIR haplotype.

Fauriat C; Andersson S; Björklund AT; Carlsten M; Schaffer M; Björkström NK; Baumann BC; Michaëlsson J; Ljunggren H-G; Malmberg K-J
Article: BMC IMMUNOLOGY. 2008;9:41

The frequency of CD127low expressing CD4+CD25high T regulatory cells is inversely correlated with human T lymphotrophic virus type-1 (HTLV-1) proviral load in HTLV-1-infection and HTLV-1-associated myelopathy/tropical spastic paraparesis.

Michaëlsson J; Barbosa HMR; Jordan KA; Chapman JM; Brunialti MKC; Neto WK; Nukui Y; Sabino EC; Chieia MA; Oliveira ASB; Nixon DF; Kallas EG
Article: CLINICAL IMMUNOLOGY. 2008;128(1):46-56

Expansion of CD56- NK cells in chronic HCV/HIV-1 co-infection: reversion by antiviral treatment with pegylated IFNalpha and ribavirin.

Gonzalez VD; Falconer K; Michaëlsson J; Moll M; Reichard O; Alaeus A; Sandberg JK
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2008;330(1-2):64-74

Application of nine-color flow cytometry for detailed studies of the phenotypic complexity and functional heterogeneity of human lymphocyte subsets.

Gonzalez VD; Björkström NK; Malmberg K-J; Moll M; Kuylenstierna C; Michaëlsson J; Ljunggren H-G; Sandberg JK
Article: JOURNAL OF INFECTIOUS DISEASES. 2008;197(1):117-125

Immune reconstitution of CD56(dim) NK cells in individuals with primary HIV-1 infection treated with interleukin-2.

Michaëlsson J; Long BR; Loo CP; Lanier LL; Spotts G; Hecht FM; Nixon DF
Article: CLINICAL AND VACCINE IMMUNOLOGY. 2008;15(1):120-130

Elevated frequency of gamma interferon-producing NK cells in healthy adults vaccinated against influenza virus.

Long BR; Michaelsson J; Loo CP; Ballan WM; Vu B-AN; Hecht FM; Lanier LL; Chapman JM; Nixon DF
Article: IMMUNOLOGY. 2007;122(2):291-301

Activating and inhibitory receptors on synovial fluid natural killer cells of arthritis patients: role of CD94/NKG2A in control of cytokine secretion.

de Matos CT; Berg L; Michaëlsson J; Felländer-Tsai L; Kärre K; Söderström K
Article: JOURNAL OF IMMUNOLOGY. 2007;179(5):3362-3370

Natural killer cells in perinatally HIV-1-infected children exhibit less degranulation compared to HIV-1-exposed uninfected children and their expression of KIR2DL3, NKG2C, and NKp46 correlates with disease severity.

Ballan WM; Vu B-AN; Long BR; Loo CP; Michaëlsson J; Barbour JD; Lanier LL; Wiznia AA; Abadi J; Fennelly GJ; Rosenberg MG; Nixon DF
Article: JOURNAL OF VIROLOGY. 2007;81(11):5759-5765

Human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T(EMRA) cells in early infection are linked to control of HIV-1 viremia and predict the subsequent viral load set point.

Northfield JW; Loo CP; Barbour JD; Spotts G; Hecht FM; Klenerman P; Nixon DF; Michaëlsson J
Article: JOURNAL OF IMMUNOLOGY. 2007;178(2):647-651

Cutting Edge: KIR3DS1, a gene implicated in resistance to progression to AIDS, encodes a DAP12-associated receptor expressed on NK cells that triggers NK cell activation.

Carr WH; Rosen DB; Arase H; Nixon DF; Michaelsson J; Lanier LL
Article: JOURNAL OF IMMUNOLOGY. 2006;176(10):5741-5748

Regulation of T cell responses in the developing human fetus.

Michaëlsson J; Mold JE; McCune JM; Nixon DF
Article: JOURNAL OF MOLECULAR BIOLOGY. 2006;356(2):382-396

Structural basis of the differential stability and receptor specificity of H-2Db in complex with murine versus human beta2-microglobulin.

Achour A; Michaëlsson J; Harris RA; Ljunggren H-G; Kärre K; Schneider G; Sandalova T
Article: ACTA CRYSTALLOGRAPHICA SECTION F: STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS. 2005;61(Pt 12):1090-1093

Expression, refolding and crystallization of murine MHC class I H-2Db in complex with human beta2-microglobulin.

Sandalova T; Michaëlsson J; Harris RA; Ljunggren H-G; Kärre K; Schneider G; Achour A
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2005;280(29):27069-27075

A structural basis for CD8+ T cell-dependent recognition of non-homologous peptide ligands: implications for molecular mimicry in autoreactivity.

Sandalova T; Michaëlsson J; Harris RA; Odeberg J; Schneider G; Kärre K; Achour A
Article: MICROBES AND INFECTION. 2005;7(7-8):1063-1065

CD4+CD25+ regulatory T cells in HIV infection.

Nixon DF; Aandahl EM; Michaëlsson J
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2004;34(6):1646-1653

Loss or mismatch of MHC class I is sufficient to trigger NK cell-mediated rejection of resting lymphocytes in vivo - role of KARAP/DAP12-dependent and -independent pathways.

Oberg L; Johansson S; Michaëlsson J; Tomasello E; Vivier E; Kärre K; Höglund P
Article: JOURNAL OF IMMUNOLOGY. 2004;172(9):5504-5511

Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition.

Velloso LM; Michaëlsson J; Ljunggren H-G; Schneider G; Achour A
Article: JOURNAL OF VIROLOGY. 2004;78(5):2454-2459

Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens.

Aandahl EM; Michaëlsson J; Moretto WJ; Hecht FM; Nixon DF
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2003;33(10):2727-2735

Regulation of perforin-independent NK cell-mediated cytotoxicity.

Wallin RPA; Screpanti V; Michaëlsson J; Grandien A; Ljunggren H-G
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2002;196(11):1403-1414

A signal peptide derived from hsp60 binds HLA-E and interferes with CD94/NKG2A recognition.

Michaëlsson J; Teixeira de Matos C; Achour A; Lanier LL; Kärre K; Söderström K
Article: IMMUNITY. 2002;17(6):757-768

A structural basis for LCMV immune evasion: subversion of H-2D(b) and H-2K(b) presentation of gp33 revealed by comparative crystal structure.Analyses.

Achour A; Michaëlsson J; Harris RA; Odeberg J; Grufman P; Sandberg JK; Levitsky V; Kärre K; Sandalova T; Schneider G
Article: CANCER RESEARCH. 2002;62(4):1116-1122

Apoptosis-dependent subversion of the T-lymphocyte epitope hierarchy in lymphoma cells.

Castiglioni P; Martin-Fontecha A; Milan G; Tomajer V; Magni F; Michaelsson J; Rugarli C; Rosato A; Bellone M
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2002;55(2):129-139

The role of an exposed loop in the alpha2 domain in the mouse MHC class I H-2Dd molecule for recognition by the monoclonal antibody 34-5-8S and the NK-cell receptor Ly49A.

Waldenström M; Achour A; Michaelsson J; Rölle A; Kärre K
Article: JOURNAL OF IMMUNOLOGY. 2002;168(2):793-800

NK cell inhibitory receptor Ly-49C residues involved in MHC class I binding.

Sundbäck J; Achour A; Michaëlsson J; Lindström H; Kärre K
Article: JOURNAL OF IMMUNOLOGY. 2001;166(12):7327-7334

MHC class I recognition by NK receptors in the Ly49 family is strongly influenced by the beta 2-microglobulin subunit.

Michaëlsson J; Achour A; Rölle A; Kärre K
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2001;31(3):869-875

Purified MHC class I molecules inhibit activated NK cells in a cell-free system in vitro.

Kambayashi T; Michaëlsson J; Fahlén L; Chambers BJ; Sentman CL; Kärre K; Ljunggren HG
Article: JOURNAL OF IMMUNOLOGY. 2000;165(9):4964-4969

Emergence of CD8+ T cells expressing NK cell receptors in influenza A virus-infected mice.

Kambayashi T; Assarsson E; Michaëlsson J; Berglund P; Diehl AD; Chambers BJ; Ljunggren HG
Article: JOURNAL OF IMMUNOLOGY. 2000;165(1):25-33

T cell tolerance based on avidity thresholds rather than complete deletion allows maintenance of maximal repertoire diversity.

Sandberg JK; Franksson L; Sundbäck J; Michaelsson J; Petersson M; Achour A; Wallin RP; Sherman NE; Bergman T; Jörnvall H; Hunt DF; Kiessling R; Kärre K
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2000;30(1):300-307

Visualization of inhibitory Ly49 receptor specificity with soluble major histocompatibility complex class I tetramers.

Michaëlsson J; Achour A; Salcedo M; Kâse-Sjöström A; Sundbäck J; Harris RA; Kärre K
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Review: FRONTIERS IN IMMUNOLOGY. 2018;9:2174

Cell-Mediated Immune Responses and Immunopathogenesis of Human Tick-Borne Encephalitis Virus-Infection.

Blom K; Cuapio A; Sandberg JT; Varnaite R; Michaëlsson J; Björkström NK; Sandberg JK; Klingström J; Lindquist L; Gredmark Russ S; Ljunggren H-G
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;140(1):318

Reply.

Marquardt N; Ljunggren H-G; Michaëlsson J
Review: NATURE REVIEWS IMMUNOLOGY. 2016;16(5):310-320

Emerging insights into natural killer cells in human peripheral tissues.

Björkström NK; Ljunggren H-G; Michaëlsson J
Editorial comment: EUROPEAN JOURNAL OF IMMUNOLOGY. 2014;44(7):2192-2196

Tracing dynamic expansion of human NK-cell subsets by high-resolution analysis of KIR repertoires and cellular differentiation.

Béziat V; Traherne J; Malmberg J-A; Ivarsson MA; Björkström NK; Retière C; Ljunggren H-G; Michaëlsson J; Trowsdale J; Malmberg K-J
Review: FRONTIERS IN IMMUNOLOGY. 2014;5:184-9

Activating killer cell Ig-like receptors in health and disease.

Ivarsson MA; Michaëlsson J; Fauriat C
Other: IMMUNITY. 2011;35(5):653-657

Killer cell immunoglobulin-like receptor workshop: insights into evolution, genetics, function, and translation.

Malmberg K-J; Michaëlsson J; Parham P; Ljunggren H-G
Meeting abstract: RETROVIROLOGY. 2009;6:p23

Preserved cellular and humoral immune responses in macaques infected with SIVmac239 and subjected to early antiretroviral therapy

Makitalo B; Walther-Jallow L; Sahin GO; Michaelsson J; Spangberg M; Thorstensson R; Fenyo E; Spetz A

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Senior Forskare, Medicin, Huddinge, Karolinska Institutet, 2022-

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Docent, Immunologi, Karolinska Institutet, 2015
MEDICINE DOKTORSEXAMEN, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2002

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