Isabelle Magalhaes

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Publikationer
CV
Populärvetenskap och samverkan

Om mig

Docent i Immunologi, Karolinska Institutet
För mer information: https://staff.ki.se/people/isabelle-magalhaes

Artiklar

Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2023;11(2):e005691

Tuned activation of MSLN-CAR T cells induces superior antitumor responses in ovarian cancer models.

Schoutrop E; Poiret T; El-Serafi I; Zhao Y; He R; Moter A; Henriksson J; Hassan M; Magalhaes I; Mattsson J
Article: ONCOIMMUNOLOGY. 2022;11(1):2093426

Trogocytosis and fratricide killing impede MSLN-directed CAR T cell functionality.

Schoutrop E; Renken S; Micallef Nilsson I; Hahn P; Poiret T; Kiessling R; Wickström SL; Mattsson J; Magalhaes I
Article: SEMINARS IN CANCER BIOLOGY. 2022;86(Pt 3):207-223

Molecular, cellular and systemic aspects of epithelial ovarian cancer and its tumor microenvironment.

Schoutrop E; Moyano-Galceran L; Lheureux S; Mattsson J; Lehti K; Dahlstrand H; Magalhaes I
Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2022;10(6):e004458

Targeting of Nrf2 improves antitumoral responses by human NK cells, TIL and CAR T cells during oxidative stress.

Renken S; Nakajima T; Magalhaes I; Mattsson J; Lundqvist A; Arnér ESJ; Kiessling R; Wickström SL
Article: CANCER RESEARCH. 2021;81(11):3022-3035

Mesothelin-Specific CAR T Cells Target Ovarian Cancer.

Schoutrop E; El-Serafi I; Poiret T; Zhao Y; Gultekin O; He R; Moyano-Galceran L; Carlson JW; Lehti K; Hassan M; Magalhaes I; Mattsson J
Article: ADVANCES IN THERAPY. 2020;37(12):5023-5031

Mesothelin Expression in Patients with High-Grade Serous Ovarian Cancer Does Not Predict Clinical Outcome But Correlates with CD11c+ Expression in Tumor.

Magalhaes I; Fernebro J; Abd Own S; Glaessgen D; Corvigno S; Remberger M; Mattsson J; Dahlstrand H
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:1300

Recruitment of MAIT Cells to the Intervillous Space of the Placenta by Placenta-Derived Chemokines.

Solders M; Gorchs L; Tiblad E; Gidlöf S; Leeansyah E; Dias J; Sandberg JK; Magalhaes I; Lundell A-C; Kaipe H
Article: ONCOIMMUNOLOGY. 2019;8(2):e1535730

Immune profiling and identification of prognostic immune-related risk factors in human ovarian cancer.

Rådestad E; Klynning C; Stikvoort A; Mogensen O; Nava S; Magalhaes I; Uhlin M
Article: CYTOTHERAPY. 2018;20(7):941-951

Media evaluation for production and expansion of anti-CD19 chimeric antigen receptor T cells.

Alnabhan R; Gaballa A; Mörk L-M; Mattsson J; Uhlin M; Magalhaes I
Article: JOURNAL OF IMMUNOTHERAPY. 2018;41(2):73-83

CD19 Chimeric Antigen Receptor T Cells From Patients With Chronic Lymphocytic Leukemia Display an Elevated IFN-γ Production Profile.

Magalhaes I; Kalland I; Kochenderfer JN; Österborg A; Uhlin M; Mattsson J
Article: CLINICAL TRANSPLANTATION. 2017;31(8)

No effect of HLA-C mismatch after allogeneic hematopoietic stem cell transplantation with unrelated donors and T-cell depletion in patients with hematological malignancies.

Magalhaes I; Uhlin M; Schaffer M; Sundin M; Hauzenberger D; Remberger M; Mattsson J
Article: SCIENTIFIC REPORTS. 2017;7(1):6123

MAIT cells accumulate in placental intervillous space and display a highly cytotoxic phenotype upon bacterial stimulation.

Solders M; Gorchs L; Erkers T; Lundell A-C; Nava S; Gidlöf S; Tiblad E; Magalhaes I; Kaipe H
Article: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2017;59:29-36

IL-7δ5 protein is expressed in human tissues and induces expression of the oxidized low density lipoprotein receptor 1 (OLR1) in CD14+ monocytes.

Rane L; Rahman S; Magalhaes I; Ambati A; Andersson J; Zumla A; Brighenti S; Maeurer MJ
Article: JOURNAL OF IMMUNOTHERAPY. 2017;40(4):132-139

A Preliminary Report: Radical Surgery and Stem Cell Transplantation for the Treatment of Patients With Pancreatic Cancer.

Omazic B; Ayoglu B; Löhr M; Segersvärd R; Verbeke C; Magalhaes I; Potacova Z; Mattsson J; Terman A; Ghazi S; Albiin N; Kartalis N; Nilsson P; Poiret T; Zhenjiang L; Heuchel R; Schwenk JM; Permert J; Maeurer MJ; Ringden O
Article: FRONTIERS IN IMMUNOLOGY. 2017;8:1861

Mucosal-Associated Invariant T Cells Display a Poor Reconstitution and Altered Phenotype after Allogeneic Hematopoietic Stem Cell Transplantation.

Solders M; Erkers T; Gorchs L; Poiret T; Remberger M; Magalhaes I; Kaipe H
Article: ONCOTARGET. 2016;7(46):74686-74700

Selenite promotes all-trans retinoic acid-induced maturation of acute promyelocytic leukemia cells.

Misra S; Selvam AK; Wallenberg M; Ambati A; Matolcsy A; Magalhaes I; Lauter G; Björnstedt M
Article: ONCOTARGET. 2016;7(21):30230-30240

Both high and low levels of cellular Epstein-Barr virus DNA in blood identify failure after hematologic stem cell transplantation in conjunction with acute GVHD and type of conditioning.

Li Q; Rane L; Poiret T; Zou J; Magalhaes I; Ahmed R; Du Z; Vudattu N; Meng Q; Gustafsson-Jernberg Å; Winiarski J; Ringdén O; Maeurer M; Remberger M; Ernberg I
Article: IMMUNOLOGY. 2015;145(3):357-366

H1N1 viral proteome peptide microarray predicts individuals at risk for H1N1 infection and segregates infection versus Pandemrix(®) vaccination.

Ambati A; Valentini D; Montomoli E; Lapini G; Biuso F; Wenschuh H; Magalhaes I; Maeurer M
Article: TRANSPLANT INFECTIOUS DISEASE. 2015;17(3):371-379

Immunogenicity of virosomal adjuvanted trivalent influenza vaccination in allogeneic stem cell transplant recipients.

Ambati A; Einarsdottir S; Magalhaes I; Poiret T; Bodenstein R; LeBlanc K; Brune M; Maeurer M; Ljungman P
Article: JOURNAL OF CLINICAL INVESTIGATION. 2015;125(4):1752-1762

Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients.

Magalhaes I; Pingris K; Poitou C; Bessoles S; Venteclef N; Kiaf B; Beaudoin L; Da Silva J; Allatif O; Rossjohn J; Kjer-Nielsen L; McCluskey J; Ledoux S; Genser L; Torcivia A; Soudais C; Lantz O; Boitard C; Aron-Wisnewsky J; Larger E; Clément K; Lehuen A
Article: FRONTIERS IN IMMUNOLOGY. 2015;6:341-7

iNKT and MAIT Cell Alterations in Diabetes.

Magalhaes I; Kiaf B; Lehuen A
Article: JOURNAL OF IMMUNOTHERAPY. 2014;37(8):416-425

TCR+CD4-CD8- T cells in antigen-specific MHC class I-restricted T-cell responses after allogeneic hematopoietic stem cell transplantation.

Ahmed RK; Poiret T; Ambati A; Rane L; Remberger M; Omazic B; Vudattu NK; Winiarski J; Ernberg I; Axelsson-Robertson R; Magalhaes I; Castelli C; Ringden O; Maeurer M
Article: BMC IMMUNOLOGY. 2014;15:25

Reduced plasma levels of soluble interleukin-7 receptor during graft-versus-host disease (GVHD) in children and adults.

Poiret T; Rane L; Remberger M; Omazic B; Gustafsson-Jernberg A; Vudattu NK; Ahmed R; Ernberg I; Winiarski J; Magalhaes I; Ringden O; Maeurer M
Article: BMC INFECTIOUS DISEASES. 2014;14:319

Difference in immune response in vaccinated and unvaccinated Swedish individuals after the 2009 influenza pandemic.

Magalhaes I; Eriksson M; Linde C; Muhammad R; Rane L; Ambati A; Axelsson-Robertson R; Khalaj B; Alvarez-Corrales N; Lapini G; Montomoli E; Linde A; Pedersen NL; Maeurer M
Article: JOURNAL OF IMMUNOTHERAPY. 2013;36(8):432-441

Cord blood T cells cultured with IL-7 in addition to IL-2 exhibit a higher degree of polyfunctionality and superior proliferation potential.

Berglund S; Gertow J; Magalhaes I; Mattsson J; Uhlin M
Article: THORAX. 2013;68(3):269-276

BCG-specific IgG-secreting peripheral plasmablasts as a potential biomarker of active tuberculosis in HIV negative and HIV positive patients.

Ashenafi S; Aderaye G; Zewdie M; Raqib R; Bekele A; Magalhaes I; Lema B; Habtamu M; Rekha RS; Aseffa G; Maeurer M; Aseffa A; Svensson M; Andersson J; Brighenti S
Article: JOURNAL OF INFECTIOUS DISEASES. 2012;205 Suppl 2:S301-S315

The immunological footprint of Mycobacterium tuberculosis T-cell epitope recognition.

Axelsson-Robertson R; Magalhaes I; Parida SK; Zumla A; Maeurer M
Article: MOLECULAR MEDICINE. 2012;18(1):647-658

Prime-boost vaccination with rBCG/rAd35 enhances CD8⁺ cytolytic T-cell responses in lesions from Mycobacterium tuberculosis-infected primates.

Rahman S; Magalhaes I; Rahman J; Ahmed RK; Sizemore DR; Scanga CA; Weichold F; Verreck F; Kondova I; Sadoff J; Thorstensson R; Spångberg M; Svensson M; Andersson J; Maeurer M; Brighenti S
Article: BMC INFECTIOUS DISEASES. 2012;12:41

Pattern recognition and cellular immune responses to novel Mycobacterium tuberculosis-antigens in individuals from Belarus.

Ahmed RK; Rohava Z; Balaji KN; Hoffner SE; Gaines H; Magalhaes I; Zumla A; Skrahina A; Maeurer MJ
Article: JOURNAL OF GENERAL VIROLOGY. 2012;93(Pt 2):247-258

Generation of T-cell receptors targeting a genetically stable and immunodominant cytotoxic T-lymphocyte epitope within hepatitis C virus non-structural protein 3.

Pasetto A; Frelin L; Brass A; Yasmeen A; Koh S; Lohmann V; Bartenschlager R; Magalhaes I; Maeurer M; Sällberg M; Chen M
Article: GENES AND IMMUNITY. 2011;12(7):513-522

Increased (6 exon) interleukin-7 production after M. tuberculosis infection and soluble interleukin-7 receptor expression in lung tissue.

Rane L; Rahman S; Magalhaes I; Ahmed R; Spångberg M; Kondova I; Verreck F; Andersson J; Brighenti S; Maeurer MJ
Article: IMMUNOLOGY. 2010;131(1):128-140

High content cellular immune profiling reveals differences between rhesus monkeys and men.

Magalhaes I; Vudattu NK; Ahmed RK; Kühlmann-Berenzon S; Ngo Y; Sizemore DR; Wehlin L; Weichold F; Andersson J; Skeiky YAW; Sadoff J; Gaines H; Thorstensson R; Spångberg M; Maeurer MJ
Article: CLINICAL AND VACCINE IMMUNOLOGY. 2009;16(4):567-573

Major histocompatibility complex class II molecule-human immunodeficiency virus peptide analysis using a microarray chip.

Gaseitsiwe S; Valentini D; Ahmed R; Mahdavifar S; Magalhaes I; Zerweck J; Schutkowski M; Gautherot E; Montero F; Ehrnst A; Reilly M; Maeurer M
Article: GENES AND IMMUNITY. 2009;10(2):132-140

Expression analysis and functional activity of interleukin-7 splice variants.

Vudattu NK; Magalhaes I; Hoehn H; Pan D; Maeurer MJ
Article: JOURNAL OF IMMUNOTHERAPY. 2008;31(9):840-848

Tumor antigen-specific T-cells are Present in the CD8alphaalpha+ T-cell effector-memory pool.

Magalhaes I; Vudattu NK; Jäger E; Maeurer MJ
Article: PLOS ONE. 2008;3(12):e3840

Pattern recognition in pulmonary tuberculosis defined by high content peptide microarray chip analysis representing 61 proteins from M. tuberculosis.

Gaseitsiwe S; Valentini D; Mahdavifar S; Magalhaes I; Hoft DF; Zerweck J; Schutkowski M; Andersson J; Reilly M; Maeurer MJ
Article: PLOS ONE. 2008;3(11):e3790

rBCG induces strong antigen-specific T cell responses in rhesus macaques in a prime-boost setting with an adenovirus 35 tuberculosis vaccine vector.

Magalhaes I; Sizemore DR; Ahmed RK; Mueller S; Wehlin L; Scanga C; Weichold F; Schirru G; Pau MG; Goudsmit J; Kühlmann-Berenzon S; Spångberg M; Andersson J; Gaines H; Thorstensson R; Skeiky YAW; Sadoff J; Maeurer M
Article: VIRUS RESEARCH. 2008;131(1):106-110

Human papillomavirus 16 E6, L1, L2 and E2 gene variants in cervical lesion progression.

Lee K; Magalhaes I; Clavel C; Briolat J; Birembaut P; Tommasino M; Zehbe I
Article: INTERNATIONAL JOURNAL OF CANCER. 2007;121(7):1512-1519

Reduced numbers of IL-7 receptor (CD127) expressing immune cells and IL-7-signaling defects in peripheral blood from patients with breast cancer.

Vudattu NK; Magalhaes I; Schmidt M; Seyfert-Margolis V; Maeurer MJ
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Review: METHODS IN MOLECULAR BIOLOGY. 2020;2098:3-21

MAIT Cells in Health and Disease.

Magalhaes I; Solders M; Kaipe H
Review: EXPERT OPINION ON BIOLOGICAL THERAPY. 2019;19(8):811-827

Facing the future: challenges and opportunities in adoptive T cell therapy in cancer.

Magalhaes I; Carvalho-Queiroz C; Hartana CA; Kaiser A; Lukic A; Mints M; Nilsson O; Grönlund H; Mattsson J; Berglund S
Review: IMMUNOTHERAPY. 2019;11(4):335-345

Metabolic regulation of CAR T cell function by the hypoxic microenvironment in solid tumors.

Schurich A; Magalhaes I; Mattsson J
Review: FRONTIERS IN IMMUNOLOGY. 2019;10:2309

The Metabolic Profile of Tumor and Virally Infected Cells Shapes Their Microenvironment Counteracting T Cell Immunity.

Magalhaes I; Yogev O; Mattsson J; Schurich A
Review: EXPERT OPINION ON BIOLOGICAL THERAPY. 2017;17(6):691-699

Advances in umbilical cord blood cell therapy: the present and the future.

Berglund S; Magalhaes I; Gaballa A; Vanherberghen B; Uhlin M
Other: M S-MEDECINE SCIENCES. 2015;31(8-9):717-719

[Mucosal-associated invariant T cells in obesity and type 2 diabetes].

Magalhaes I; Lehuen A
Letter: TRANSPLANTATION. 2014;98(12):e95-e96

Allogeneic Hematopoietic Cell Transplantation for GATA2 Deficiency in a Patient With Disseminated Human Papillomavirus Disease.

Maeurer M; Magalhaes I; Andersson J; Ljungman P; Sandholm E; Uhlin M; Mattsson J; Ringdén O
Review: CURRENT OPINION IN IMMUNOLOGY. 2014;27:83-88

Invariant NKT cell development: focus on NOD mice.

Ghazarian L; Simoni Y; Magalhaes I; Lehuen A
Other: EUROPEAN JOURNAL OF IMMUNOLOGY. 2010;40(5):1228-1231

Training in immunology of relevance to global health issues in resource poor settings.

Parida SK; Magalhaes I; Dubois P; Janetzki S
Meeting abstract: CLINICAL IMMUNOLOGY. 2006;119:S116-S117

Interleukin-7 receptor (IL-7R) mediated signaling effects in immune cells:novel readout for 'immune competence'

Vudattu N; Magalhaes I; Ahmed R; Schmidt M; Khademi M; Olsson T; Maeurer M
Meeting abstract: JOURNAL OF IMMUNOTHERAPY. 2005;28(6):632

Elevated antigen-specific IL2 production in CD8AA+T-cells in patients with melanoma responding to therapy

Magalhaes I; Vudattu NK; Karbach J; Juelch M; Castelli C; Jaeger E; Maeurer M
Meeting abstract: JOURNAL OF IMMUNOTHERAPY. 2005;28(6):626-627

Reduced expression of the IL-7 receptor (CD127) on CD8AA+T-cells and IL-7 signalling defects in patients with breast cancer

Vudattu NK; Magalhaes I; Schmidt M; Maeurer M

Anställningar

Anknuten till Forskning, Medicin, Huddinge, Karolinska Institutet, 2024-2026

Examina och utbildning

Docent, immunologi, Karolinska Institutet, 2021
Medicine Doktorsexamen, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2009

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Anställningar

Examina och utbildning

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