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Fredrik Lanner

Forskarassistent

Postadress : Institutionen för klinisk vetenskap, intervention och teknik (CLINTEC), H9, Enheten för obstetrik och gynekologi, Karolinska Universitetssjukhuset, K 57 141 86 Stockholm

Publikationer

Biotechnology: At the heart of gene edits in human embryos
Winblad N, Lanner F
Nature 2017;548(7668):398-400

Comprehensive Cell Surface Protein Profiling Identifies Specific Markers of Human Naive and Primed Pluripotent States
Collier Aj, Panula Sp, Schell Jp, Chovanec P, Plaza Reyes A, Petropoulos S, et al
Cell stem cell 2017;20(6):874-890.e7

Integration of Subretinal Suspension Transplants of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells in a Large-Eyed Model of Geographic Atrophy
Petrus-reurer S, Bartuma H, Aronsson M, Westman S, Lanner F, André H, et al
Investigative ophthalmology & visual science 2017;58(2):1314-1322

Overexpression of Trophoblast Stem Cell-Enriched MicroRNAs Promotes Trophoblast Fate in Embryonic Stem Cells
Nosi U, Lanner F, Huang T, Cox B
Cell reports 2017;19(6):1101-1109

Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo
Posfai E, Petropoulos S, De Barros Fr, Schell Jp, Jurisica I, Sandberg R, et al
eLife 2017;6():-

The E-cadherin/AmotL2 complex organizes actin filaments required for epithelial hexagonal packing and blastocyst hatching
Hildebrand S, Hultin S, Subramani A, Petropoulos S, Zhang Y, Cao X, et al
Scientific reports 2017;7(1):9540-

Towards a CRISPR view of early human development: applications, limitations and ethical concerns of genome editing in human embryos
Plaza Reyes A, Lanner F
Development (Cambridge, England) 2017;144(1):3-7

Adult Human and Mouse Ovaries Lack DDX4-Expressing Functional Oogonial Stem Cells EDITORIAL COMMENT
Zhang H, Panula S, Petropoulos S, Edsgard D, Busayavalasa K, Liu L, et al
OBSTETRICAL & GYNECOLOGICAL SURVEY 2016;71(1):29-30

Characterization and target genes of nine human PRD-like homeobox domain genes expressed exclusively in early embryos
Madissoon E, Jouhilahti Em, Vesterlund L, Töhönen V, Krjutškov K, Petropoulous S, et al
Scientific reports 2016;6():28995-

Corrigendum: Characterization and target genes of nine human PRD-like homeobox domain genes expressed exclusively in early embryos
Madissoon E, Jouhilahti Em, Vesterlund L, Töhönen V, Krjutškov K, Petropoulos S, et al
Scientific reports 2016;6():32053-

Single-cell analyses of X Chromosome inactivation dynamics and pluripotency during differentiation
Chen G, Schell Jp, Benitez Ja, Petropoulos S, Yilmaz M, Reinius B, et al
Genome research 2016;26(10):1342-1354

Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos
Petropoulos S, Edsgärd D, Reinius B, Deng Q, Panula Sp, Codeluppi S, et al
Cell 2016;167(1):285-

Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos
Petropoulos S, Edsgärd D, Reinius B, Deng Q, Panula Sp, Codeluppi S, et al
Cell 2016;165(4):1012-26

Single-cell RNA sequencing: revealing human pre-implantation development, pluripotency and germline development
Petropoulos S, Panula Sp, Schell Jp, Lanner F
Journal of internal medicine 2016;280(3):252-64

Single-cell sequencing of the small-RNA transcriptome
Faridani Or, Abdullayev I, Hagemann-jensen M, Schell Jp, Lanner F, Sandberg R
Nature biotechnology 2016;34(12):1264-1266

The human PRD-like homeobox gene LEUTX has a central role in embryo genome activation
Jouhilahti Em, Madissoon E, Vesterlund L, Töhönen V, Krjutškov K, Plaza Reyes A, et al
Development (Cambridge, England) 2016;143(19):3459-3469

Xeno-Free and Defined Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells Functionally Integrate in a Large-Eyed Preclinical Model
Plaza Reyes A, Petrus-reurer S, Antonsson L, Stenfelt S, Bartuma H, Panula S, et al
Stem cell reports 2016;6(1):9-17

Adult human and mouse ovaries lack DDX4-expressing functional oogonial stem cells
Zhang H, Panula S, Petropoulos S, Edsgärd D, Busayavalasa K, Liu L, et al
Nature medicine 2015;21(10):1116-8

Lineage specification in the early mouse embryo
Lanner F
Experimental cell research 2014;321(1):32-9

Hypoxia-induced arterial differentiation requires adrenomedullin and notch signaling
Lanner F, Lee Kl, Ortega Gc, Sohl M, Li X, Jin S, et al
Stem cells and development 2013;22(9):1360-9

Interaction domains of Sos1/Grb2 are finely tuned for cooperative control of embryonic stem cell fate
Findlay Gm, Smith Mj, Lanner F, Hsiung Ms, Gish Gd, Petsalaki E, et al
Cell 2013;152(5):1008-20

Location of transient ectodermal progenitor potential in mouse development
Li Ly, Liu C, Biechele S, Zhu Qq, Song L, Lanner F, et al
DEVELOPMENT 2013;140(22):4533-43

Porcn-dependent Wnt signaling is not required prior to mouse gastrulation
Biechele S, Cockburn K, Lanner F, Cox Bj, Rossant J
DEVELOPMENT 2013;140(14):2961-71

Cell-Surface Proteomics Identifies Lineage-Specific Markers of Embryo-Derived Stem Cells
Rugg-gunn Pj, Cox Bj, Lanner F, Sharma P, Ignatchenko V, Mcdonald Ach, et al
DEVELOPMENTAL CELL 2012;22(4):887-901

Constitutive heterochromatin reorganization during somatic cell reprogramming
Fussner E, Djuric U, Strauss M, Hotta A, Perez-iratxeta C, Lanner F, et al
EMBO JOURNAL 2011;30(9):1778-89

Numblike and Numb differentially affect p53 and Sonic Hedgehog signaling
Liu Ln, Lanner F, Lendahl U, Das D
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2011;413(3):426-31

Control of Notch-ligand endocytosis by ligand-receptor interaction
Hansson Em, Lanner F, Das D, Mutvei A, Marklund U, Ericson J, et al
JOURNAL OF CELL SCIENCE 2010;123(17):2931-42

FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst
Yamanaka Y, Lanner F, Rossant J
DEVELOPMENT 2010;137(5):715-24

Heparan Sulfation-Dependent Fibroblast Growth Factor Signaling Maintains Embryonic Stem Cells Primed for Differentiation in a Heterogeneous State
Lanner F, Lee Kl, Sohl M, Holmborn K, Yang H, Wilbertz J, et al
STEM CELLS 2010;28(2):191-200

Notch induces cyclin-D1-dependent proliferation during a specific temporal window of neural differentiation in ES cells
Das D, Lanner F, Main H, Andersson Er, Bergmann O, Sahlgren C, et al
DEVELOPMENTAL BIOLOGY 2010;348(2):153-66

Sp1 mediate hypoxia induced ephrinB2 expression via a hypoxia-inducible factor independent mechanism
Sohl M, Lanner F, Farnebo F
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2010;391(1):24-7

The role of FGF/Erk signaling in pluripotent cells
Lanner F, Rossant J
DEVELOPMENT 2010;137(20):3351-60

Characterization of the murine Ephrin-B2 promoter
Sohl M, Lanner F, Farnebo F
GENE 2009;437(1-2):54-9

Assessment of NORE1A as a putative tumor suppressor in human neuroblastoma
Geli J, Kogner P, Lanner F, Natalishvili N, Juhlin C, Kiss N, et al
INTERNATIONAL JOURNAL OF CANCER 2008;123(2):389-394

Notch signaling regulates platelet-derived growth factor receptor-beta expression in vascular smooth muscle cells
Jin S, Hansson Em, Tikka S, Lanner F, Sahlgren C, Farnebo F, et al
CIRCULATION RESEARCH 2008;102(12):1483-91

Functional arterial and venous fate is determined by graded VEGF signaling and notch status during embryonic stem cell differentiation
Lanner F, Sohl M, Farnebo F
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 2007;27(3):487-93

Lentiviral rescue of vascular endothelial growth factor receptor-2 expression in Flk1-/- embryonic stem cells shows early priming of endothelial precursors
Li Xj, Edholm D, Lanner F, Breier G, Farnebo F, Dimberg A, et al
STEM CELLS 2007;25(12):2987-95

The Ras effectors NORE1A and RASSF1A are frequently inactivated in pheochromocytoma and abdominal paraganglioma
Geli J, Kiss N, Lanner F, Foukakis T, Natalishvili N, Larsson O, et al
ENDOCRINE-RELATED CANCER 2007;14(1):125-34

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