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Christopher Sundling

Anknuten

Besöksadress : B2:03, Karolinska Universitetssjukhuset, Solna 171 76 Stockholm
Postadress : Institutionen för medicin, Solna (MedS), K2, Forskargrupp A Färnert, B3:03, Karolinska Universitetssjukhuset, Solna 171 76 Stockholm
Leveransadress : B3:03, Karolinska Universitetssjukhuset, Solna 171 76 Stockholm

Publikationer

Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells
Kräutler Nj, Suan D, Butt D, Bourne K, Hermes Jr, Chan Td, et al
The Journal of experimental medicine 2017;214(5):1259-1267

Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability
Zhao X, Howell Ka, He S, Brannan Jm, Wec Az, Davidson E, et al
Cell 2017;169(5):891-904.e15

Plasma cell and memory B cell differentiation from the germinal center
Suan D, Sundling C, Brink R
Current opinion in immunology 2017;45():97-102

CD138 and CD31 Double-Positive Cells Comprise the Functional Antibody-Secreting Plasma Cell compartment in Primate Bone Marrow
Martinez-murillo P, Pramanik L, Sundling C, Hultenby K, Wretenberg P, Spangberg M, et al
FRONTIERS IN IMMUNOLOGY 2016;:242-

CTI special feature on innate immune responses and vaccine design
Sundling C, Sandgren K
Clinical & translational immunology 2016;5(8):e96-

High-Resolution Longitudinal Study of HIV-1 Env Vaccine-Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence
Wang Ym, Sundling C, Wilson R, O'dell S, Chen Yj, Dai Kf, et al
JOURNAL OF IMMUNOLOGY 2016;196(9):3729-43

HIV-1 Vaccine-elicited Antibodies Reverted to Their Inferred Naive Germline Reveal Associations between Binding Affinity and in vivo Activation
Dai K, Khan Sn, Wang Y, He L, Guenaga J, Ingale J, et al
Scientific reports 2016;6():20987-

Diverse antibody genetic and recognition properties revealed following HIV-1 envelope glycoprotein immunization
Phad Ge, Vázquez Bernat N, Feng Y, Ingale J, Martinez Murillo Pa, O'dell S, et al
Journal of immunology (Baltimore, Md. : 1950) 2015;194(12):5903-14

Primate immune responses to HIV-1 Env formulated in the saponin-based adjuvant AbISCO-100 in the presence or absence of TLR9 co-stimulation
Martinez P, Sundling C, O'dell S, Mascola Jr, Wyatt Rt, Karlsson Hedestam Gb
Scientific reports 2015;5():8925-

Rhesus Macaque B-Cell Responses to an HIV-1 Trimer Vaccine Revealed by Unbiased Longitudinal Repertoire Analysis
Dai K, He L, Khan Sn, O'dell S, Mckee K, Tran K, et al
mBio 2015;6(6):e01375-15

A simple and safe technique for longitudinal bone marrow aspiration in cynomolgus and rhesus macaques
Spångberg M, Martinez P, Fredlund H, Karlsson Hedestam Gb, Sundling C
Journal of immunological methods 2014;408():137-41

HIV-1 receptor binding site-directed antibodies using a VH1-2 gene segment orthologue are activated by Env trimer immunization
Navis M, Tran K, Bale S, Phad Ge, Guenaga J, Wilson R, et al
PLoS pathogens 2014;10(8):e1004337-

Single-cell and deep sequencing of IgG-switched macaque B cells reveal a diverse Ig repertoire following immunization
Sundling C, Zhang Z, Phad Ge, Sheng Z, Wang Y, Mascola Jr, et al
Journal of immunology (Baltimore, Md. : 1950) 2014;192(8):3637-44

Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign
Tran K, Poulsen C, Guenaga J, De Val N, Wilson R, Sundling C, et al
Proceedings of the National Academy of Sciences of the United States of America 2014;111(7):E738-47

Immunization of Macaques With Soluble HIV Type 1 and Influenza Virus Envelope Glycoproteins Results in a Similarly Rapid Contraction of Peripheral B-Cell Responses After Boosting
Sundling C, Martinez P, Soldemo M, Spangberg M, Bengtsson Kl, Stertman L, et al
JOURNAL OF INFECTIOUS DISEASES 2013;207(3):426-31

High-Resolution Definition of Vaccine-Elicited B Cell Responses Against the HIV Primary Receptor Binding Site
Sundling C, Li Yx, Huynh N, Poulsen C, Wilson R, O'dell S, et al
SCIENCE TRANSLATIONAL MEDICINE 2012;4(142):142ra96-

Isolation of antibody V(D)J sequences from single cell sorted rhesus macaque B cells
Sundling C, Phad G, Douagi I, Navis M, Karlsson Hedestam Gb
Journal of immunological methods 2012;386(1-2):85-93

Human and rhesus plasmacytoid dendritic cell and B-cell responses to Toll-like receptor stimulation
Gujer C, Sundling C, Seder Ra, Hedestam Gbk, Lore K
IMMUNOLOGY 2011;134(3):257-69

IFN-alpha produced by human plasmacytoid dendritic cells enhances T cell-dependent naive B cell differentiation
Gujer C, Sandgren Kj, Douagi I, Adams Wc, Sundling C, Smed-sorensen A, et al
JOURNAL OF LEUKOCYTE BIOLOGY 2011;89(6):811-21

Immunization with Wild-Type or CD4-Binding-Defective HIV-1 Env Trimers Reduces Viremia Equivalently following Heterologous Challenge with Simian-Human Immunodeficiency Virus
Sundling C, O'dell S, Douagi I, Forsell Mn, Morner A, Lore K, et al
JOURNAL OF VIROLOGY 2010;84(18):9086-95

Influence of Novel CD4 Binding-Defective HIV-1 Envelope Glycoprotein Immunogens on Neutralizing Antibody and T-Cell Responses in Nonhuman Primates
Douagi I, Forsell Mne, Sundling C, O'dell S, Feng Y, Dosenovic P, et al
JOURNAL OF VIROLOGY 2010;84(4):1683-95

Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates
Sundling C, Forsell Mne, O'dell S, Feng Y, Chakrabarti B, Rao Ss, et al
JOURNAL OF EXPERIMENTAL MEDICINE 2010;207(9):2003-17

Human B Cell Responses to TLR Ligands Are Differentially Modulated by Myeloid and Plasmacytoid Dendritic Cells
Douagi I, Gujer C, Sundling C, Adams Wc, Smed-sorensen A, Seder Ra, et al
JOURNAL OF IMMUNOLOGY 2009;182(4):1991-2001

Human Immunodeficiency Virus Type 1 Env Trimer Immunization of Macaques and Impact of Priming with Viral Vector or Stabilized Core Protein
Morner A, Douagi I, Forsell Mne, Sundling C, Dosenovic P, O'dell S, et al
JOURNAL OF VIROLOGY 2009;83(2):540-51

CTA1-DD adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization
Sundling C, Schon K, Morner A, Forsell Mne, Wyatt Rt, Thorstensson R, et al
JOURNAL OF GENERAL VIROLOGY 2008;:2954-64

Impact of In Vivo CD4 Binding Following HIV-1 Env Protein Trimer Immunizations of Rhesus Macaques
Douagi I, Forsell Mn, Sundling C, O'dell S, Dosenovic P, Li Y, et al
AIDS RESEARCH AND HUMAN RETROVIRUSES 2008;:45-46

Increased human immunodeficiency virus type 1 Env expression and antibody induction using an enhanced alphavirus vector
Forsell Mne, Mcinerney Gm, Dosenovic P, Hidmark As, Eriksson C, Liljestorm P, et al
JOURNAL OF GENERAL VIROLOGY 2007;:2774-9

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