Cecilia Williams

Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Utvalda publikationer

Article: BMC BIOLOGY. 2023;21(1):277

Ovarian ERβ cistrome and transcriptome reveal chromatin interaction with LRH-1.

Birgersson M; Indukuri R; Lindquist L; Stepanauskaite L; Luo Q; Deng Q; Archer A; Williams C
Article: COMMUNICATIONS BIOLOGY. 2023;6(1):20

High-fat diet and estrogen modulate the gut microbiota in a sex-dependent manner in mice.

Hases L; Stepanauskaite L; Birgersson M; Brusselaers N; Schuppe-Koistinen I; Archer A; Engstrand L; Williams C
Article: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 2022;1390:213-225

ERβ and Inflammation.

Hases L; Archer A; Williams C
Editorial comment: FRONTIERS IN ENDOCRINOLOGY. 2022;13:883229

Editorial: Role of Sex Steroids and Their Receptor in Cancers.

Giovannelli P; Ramaraj P; Williams C
Editorial comment: ESSAYS IN BIOCHEMISTRY. 2021;65(6):847-856

Nuclear receptors: from molecular mechanisms to therapeutics.

Frigo DE; Bondesson M; Williams C
Article: INTERNATIONAL JOURNAL OF CANCER. 2021;149(3):692-706

Genome-wide estrogen receptor β chromatin binding in human colon cancer cells reveals its tumor suppressor activity.

Indukuri R; Jafferali MH; Song D; Damdimopoulos A; Hases L; Zhao C; Archer A; Williams C
Article: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2021;53(11):1216-1225

Menopausal hormone therapies and risk of colorectal cancer: a Swedish matched-cohort study.

Liu Q; Simin J; Debelius J; Fall K; Sadr-Azodi O; Engstrand L; Williams C; Brusselaers N
Article: CANCER CELL. 2018;33(4):690-705.e9

A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers.

Berger AC; Korkut A; Kanchi RS; Hegde AM; Lenoir W; Liu W; Liu Y; Fan H; Shen H; Ravikumar V; Rao A; Schultz A; Li X; Sumazin P; Williams C; Mestdagh P; Gunaratne PH; Yau C; Bowlby R; Robertson AG; Tiezzi DG; Wang C; Cherniack AD; Godwin AK; Kuderer NM; Rader JS; Zuna RE; Sood AK; Lazar AJ; Ojesina AI; Adebamowo C; Adebamowo SN; Baggerly KA; Chen T-W; Chiu H-S; Lefever S; Liu L; MacKenzie K; Orsulic S; Roszik J; Shelley CS; Song Q; Vellano CP; Wentzensen N; Cancer Genome Atlas Research Network; Weinstein JN; Mills GB; Levine DA; Akbani R
Article: NATURE COMMUNICATIONS. 2017;8:15840

Insufficient antibody validation challenges oestrogen receptor beta research.

Andersson S; Sundberg M; Pristovsek N; Ibrahim A; Jonsson P; Katona B; Clausson C-M; Zieba A; Ramström M; Söderberg O; Williams C; Asplund A

Artiklar

Article: MOLECULAR SYSTEMS BIOLOGY. 2024;20(4):374-402

Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis.

Sommerauer C; Gallardo-Dodd CJ; Savva C; Hases L; Birgersson M; Indukuri R; Shen JX; Carravilla P; Geng K; Nørskov Søndergaard J; Ferrer-Aumatell C; Mercier G; Sezgin E; Korach-André M; Petersson C; Hagström H; Lauschke VM; Archer A; Williams C; Kutter C
Article: TOXICOLOGICAL SCIENCES. 2023;193(2):119-130

Triazole fungicides induce adipogenesis and repress osteoblastogenesis in zebrafish.

Thrikawala S; Mesmar F; Bhattacharya B; Muhsen M; Mukhopadhyay S; Flores S; Upadhyay S; Vergara L; Gustafsson J-Å; Williams C; Bondesson M
Article: PROTEIN & CELL. 2023;14(2):123-136

NDFIP1 limits cellular TAZ accumulation via exosomal sorting to inhibit NSCLC proliferation.

Cheng Y; Lu X; Li F; Chen Z; Zhang Y; Han Q; Zeng Q; Wu T; Li Z; Lu S; Williams C; Xia W
Article: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. 2023;20(5):4181

Statistical Analysis of SARS-CoV-2 Using Wastewater-Based Data of Stockholm, Sweden.

Chekkala A; Atasoy M; Williams C; Cetecioglu Z
Article: SCIENCE OF THE TOTAL ENVIRONMENT. 2023;858(Pt 3):160023

Long-term SARS-CoV-2 surveillance in the wastewater of Stockholm: What lessons can be learned from the Swedish perspective?

Perez-Zabaleta M; Archer A; Khatami K; Jafferali MH; Nandy P; Atasoy M; Birgersson M; Williams C; Cetecioglu Z
Article: CANCERS. 2022;14(24):6029

SETD7 Expression Is Associated with Breast Cancer Survival Outcomes for Specific Molecular Subtypes: A Systematic Analysis of Publicly Available Datasets.

Monteiro FL; Stepanauskaite L; Williams C; Helguero LA
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(18):10408

Colitis Induces Sex-Specific Intestinal Transcriptomic Responses in Mice.

Hases L; Birgersson M; Indukuri R; Archer A; Williams C
Journal article: ANNALS OF ONCOLOGY. 2022;33:s640

223P Gene expression profiles in endocrine-resistant breast cancer

Schagerholm C; Robertson S; Sifakis EG; Hases L; Williams C; Hartman J
Article: CANCERS. 2022;14(13):3098

Estrogen Receptor β (ESR2) Transcriptome and Chromatin Binding in a Mantle Cell Lymphoma Tumor Model Reveal the Tumor-Suppressing Mechanisms of Estrogens.

Huang D; Huang Z; Indukuri R; Bangalore Revanna C; Berglund M; Guan J; Yakimchuk K; Damdimopoulos A; Williams C; Okret S
Article: CANCERS. 2022;14(6):1414

A Systematic Review to Define the Multi-Faceted Role of Lysine Methyltransferase SETD7 in Cancer.

Monteiro FL; Williams C; Helguero LA
Article: FRONTIERS IN ENDOCRINOLOGY. 2022;13:930227

ERα and ERβ Homodimers in the Same Cellular Context Regulate Distinct Transcriptomes and Functions.

Song D; He H; Indukuri R; Huang Z; Stepanauskaite L; Sinha I; Haldosén L-A; Zhao C; Williams C
Article: METHODS IN MOLECULAR BIOLOGY. 2022;2418:203-221

An Optimized ChIP-Seq Protocol to Determine Chromatin Binding of Estrogen Receptor Beta.

Indukuri R; Damdimopoulos A; Williams C
Article: METHODS IN MOLECULAR BIOLOGY. 2022;2418:1-23

Antibody Validation for Estrogen Receptor Beta.

Birgersson M; Katona B; Lindskog C; Pontén F; Williams C
Article: METHODS IN MOLECULAR BIOLOGY. 2022;2418:313-343

Expression Profiles of Estrogen-Regulated MicroRNAs in Cancer Cells.

Archer A; Kutter C; Williams C
Article: ACTA ONCOLOGICA. 2021;60(7):881-887

Prediagnostic use of estrogen-only therapy is associated with improved colorectal cancer survival in menopausal women: a Swedish population-based cohort study.

Simin J; Liu Q; Wang X; Fall K; Williams C; Callens S; Engstrand L; Brusselaers N
Article: CANCER LETTERS. 2021;506:23-34

Blocking Fra-1 sensitizes triple-negative breast cancer to PARP inhibitor.

Song D; He H; Sinha I; Hases L; Yan F; Archer A; Haldosen L-A; Zhao C; Williams C
Article: SCIENCE OF THE TOTAL ENVIRONMENT. 2021;755(Pt 1):142939

Benchmarking virus concentration methods for quantification of SARS-CoV-2 in raw wastewater.

Jafferali MH; Khatami K; Atasoy M; Birgersson M; Williams C; Cetecioglu Z
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(3):1354

The Importance of Sex in the Discovery of Colorectal Cancer Prognostic Biomarkers.

Hases L; Ibrahim A; Chen X; Liu Y; Hartman J; Williams C
Article: FRONTIERS IN ENDOCRINOLOGY. 2021;12:650625

Estrogen Receptor Beta Influences the Inflammatory p65 Cistrome in Colon Cancer Cells.

Indukuri R; Hases L; Archer A; Williams C
Article: CANCER LETTERS. 2020;492:54-62

Intestinal estrogen receptor beta suppresses colon inflammation and tumorigenesis in both sexes.

Hases L; Indukuri R; Birgersson M; Nguyen-Vu T; Lozano R; Saxena A; Hartman J; Frasor J; Gustafsson J-Å; Katajisto P; Archer A; Williams C
Article: SCIENTIFIC REPORTS. 2020;10(1):16160

High-fat diet and estrogen impacts the colon and its transcriptome in a sex-dependent manner.

Hases L; Archer A; Indukuri R; Birgersson M; Savva C; Korach-André M; Williams C
Article: PEERJ. 2020;8:e9434

Comparison of serum exosome isolation methods on co-precipitated free microRNAs.

Cheng Y; Qu X; Dong Z; Zeng Q; Ma X; Jia Y; Li R; Jiang X; Williams C; Wang T; Xia W
Article: MABS. 2020;12(1):1794421

The Antibody Society's antibody validation webinar series.

Voskuil JLA; Bandrowski A; Begley CG; Bradbury ARM; Chalmers AD; Gomes AV; Hardcastle T; Lund-Johansen F; Plückthun A; Roncador G; Solache A; Taussig MJ; Trimmer JS; Williams C; Goodman SL
Article: JOURNAL OF CELLULAR PHYSIOLOGY. 2019;234(12):22220-22233

A miR-206 regulated gene landscape enhances mammary epithelial differentiation.

Wang J; Aydoğdu E; Mukhopadhyay S; Helguero LA; Williams C
Article: CANCER MEDICINE. 2019;8(18):7705-7719

Clinical candidate and genistein analogue AXP107-11 has chemoenhancing functions in pancreatic adenocarcinoma through G protein-coupled estrogen receptor signaling.

Mesmar F; Dai B; Ibrahim A; Hases L; Jafferali MH; Jose Augustine J; DiLorenzo S; Kang Y; Zhao Y; Wang J; Kim M; Lin C-Y; Berkenstam A; Fleming J; Williams C
Article: BMC CANCER. 2019;19(1):684

Sexual dimorphism in the incidence of human cancers.

Zheng D; Trynda J; Williams C; Vold JA; Nguyen JH; Harnois DM; Bagaria SP; McLaughlin SA; Li Z
Article: INTERNATIONAL JOURNAL OF CANCER. 2019;144(12):3086-3098

Colitis-induced colorectal cancer and intestinal epithelial estrogen receptor beta impact gut microbiota diversity.

Ibrahim A; Hugerth LW; Hases L; Saxena A; Seifert M; Thomas Q; Gustafsson J-Å; Engstrand L; Williams C
Article: METHODS IN MOLECULAR BIOLOGY. 2019;1966:79-99

Antibody Validation Strategy for Nuclear Receptors.

Katona B; Ibrahim A; Sundberg M; Williams C
Journal article: CELL SYSTEMS. 2018;7(4):422-437.e7

A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily.

Korkut A; Zaidi S; Kanchi RS; Rao S; Gough NR; Schultz A; Li X; Lorenzi PL; Berger AC; Robertson G; Kwong LN; Datto M; Roszik J; Ling S; Ravikumar V; Manyam G; Rao A; Shelley S; Liu Y; Ju Z; Hansel D; de Velasco G; Pennathur A; Andersen JB; O'Rourke CJ; Ohshiro K; Jogunoori W; Nguyen B-N; Li S; Osmanbeyoglu HU; Ajani JA; Mani SA; Houseman A; Wiznerowicz M; Chen J; Gu S; Ma W; Zhang J; Tong P; Cherniack AD; Deng C; Resar L; Cancer Genome Atlas Research Network; Weinstein JN; Mishra L; Akbani R
Article: ONCOTARGET. 2018;9(28):19730-19744

Transcriptome profiling of the interconnection of pathways involved in malignant transformation and response to hypoxia.

Danielsson F; Fasterius E; Sullivan D; Hases L; Sanli K; Zhang C; Mardinoglu A; Al-Khalili C; Huss M; Uhlén M; Williams C; Lundberg E
Journal article: CANCER RESEARCH. 2017;77:4401

Role of estrogen signaling in colon microenvironment during obesity

Archer A; Pettersson L; Gonzalez-Granillo M; Savva C; Korach-Andre M; Williams C
Journal article: CANCER RESEARCH. 2017;77:2819

Intestinal estrogen receptor beta attenuates colon cancer signaling pathways in vivo

Pettersson L; Saxena A; Vu T; Gustafsson J-A; Archer A; Williams C
Article: CANCER LETTERS. 2017;396:42-52

The histone H2A isoform Hist2h2ac is a novel regulator of proliferation and epithelial-mesenchymal transition in mammary epithelial and in breast cancer cells.

Monteiro FL; Vitorino R; Wang J; Cardoso H; Laranjeira H; Simões J; Caldas M; Henrique R; Amado F; Williams C; Jerónimo C; Helguero LA
Article: JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2017;109(3):1-14

Estrogen Receptor β as a Therapeutic Target in Breast Cancer Stem Cells.

Ma R; Karthik G-M; Lövrot J; Haglund F; Rosin G; Katchy A; Zhang X; Viberg L; Frisell J; Williams C; Linder S; Fredriksson I; Hartman J
Article: PLOS ONE. 2017;12(2):e0172832

Genome-wide effects of MELK-inhibitor in triple-negative breast cancer cells indicate context-dependent response with p53 as a key determinant.

Simon M; Mesmar F; Helguero L; Williams C
Article: ONCOTARGET. 2016;7(27):42159-42171

Estrogen receptor beta reduces colon cancer metastasis through a novel miR-205 - PROX1 mechanism.

Nguyen-Vu T; Wang J; Mesmar F; Mukhopadhyay S; Saxena A; McCollum CW; Gustafsson J-Å; Bondesson M; Williams C
Article: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2016;57(6):2689-2698

Vitamin D Induces Global Gene Transcription in Human Corneal Epithelial Cells: Implications for Corneal Inflammation.

Reins RY; Mesmar F; Williams C; McDermott AM
Article: ONCOGENE. 2016;35(15):1955-1964

RING finger protein 31 promotes p53 degradation in breast cancer cells.

Zhu J; Zhao C; Zhuang T; Jonsson P; Sinha I; Williams C; Strömblad S; Dahlman-Wright K
Article: METHODS IN MOLECULAR BIOLOGY. 2016;1366:373-393

Expression Profiles of Estrogen-Regulated MicroRNAs in Breast Cancer Cells.

Katchy A; Williams C
Article: MOLECULAR ENDOCRINOLOGY. 2015;29(11):1634-1645

Single-Molecule Sequencing Reveals Estrogen-Regulated Clinically Relevant lncRNAs in Breast Cancer.

Jonsson P; Coarfa C; Mesmar F; Raz T; Rajapakshe K; Thompson JF; Gunaratne PH; Williams C
Article: CARCINOGENESIS. 2015;36(9):1051-1060

miR-200a inhibits migration of triple-negative breast cancer cells through direct repression of the EPHA2 oncogene.

Tsouko E; Wang J; Frigo DE; Aydoğdu E; Williams C
Article: PLOS ONE. 2015;10(5):e0128239

Estrogen Receptor β2 Induces Hypoxia Signature of Gene Expression by Stabilizing HIF-1α in Prostate Cancer.

Dey P; Velazquez-Villegas LA; Faria M; Turner A; Jonsson P; Webb P; Williams C; Gustafsson J-Å; Ström AM
Article: MOLECULAR ONCOLOGY. 2014;8(8):1690-1702

miR-206 inhibits cell migration through direct targeting of the actin-binding protein coronin 1C in triple-negative breast cancer.

Wang J; Tsouko E; Jonsson P; Bergh J; Hartman J; Aydogdu E; Williams C
Article: FASEB JOURNAL. 2014;28(10):4247-4264

Fatty acid and phospholipid biosynthetic pathways are regulated throughout mammary epithelial cell differentiation and correlate to breast cancer survival.

Dória ML; Ribeiro AS; Wang J; Cotrim CZ; Domingues P; Williams C; Domingues MR; Helguero LA
Article: ONCOGENE. 2014;33(34):4340-4351

The atypical ubiquitin ligase RNF31 stabilizes estrogen receptor α and modulates estrogen-stimulated breast cancer cell proliferation.

Zhu J; Zhao C; Kharman-Biz A; Zhuang T; Jonsson P; Liang N; Williams C; Lin C-Y; Qiao Y; Zendehdel K; Strömblad S; Treuter E; Dahlman-Wright K
Article: CANCER RESEARCH. 2014;74(14):3983-3994

Genome-wide profiling of AP-1-regulated transcription provides insights into the invasiveness of triple-negative breast cancer.

Zhao C; Qiao Y; Jonsson P; Wang J; Xu L; Rouhi P; Sinha I; Cao Y; Williams C; Dahlman-Wright K
Article: ENDOCRINE-RELATED CANCER. 2014;21(2):143-160

Support of a bi-faceted role of estrogen receptor β (ERβ) in ERα-positive breast cancer cells.

Jonsson P; Katchy A; Williams C
Article: TOXICOLOGICAL SCIENCES. 2014;138(1):21-35

Coexposure to phytoestrogens and bisphenol a mimics estrogenic effects in an additive manner.

Katchy A; Pinto C; Jonsson P; Nguyen-Vu T; Pandelova M; Riu A; Schramm K-W; Samarov D; Gustafsson J-Å; Bondesson M; Williams C
Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2014;(84):e51285

Profiling of estrogen-regulated microRNAs in breast cancer cells.

Katchy A; Williams C
Article: ENDOCR DISRUPTORS (AUSTIN). 2014;2(1):e29088

Gestational bisphenol A exposure and testis development.

Williams C; Bondesson M; Krementsov DN; Teuscher C
Article: TOXICOLOGICAL SCIENCES. 2013;135(1):91-102

Studies in experimental autoimmune encephalomyelitis do not support developmental bisphenol a exposure as an environmental factor in increasing multiple sclerosis risk.

Krementsov DN; Katchy A; Case LK; Carr FE; Davis B; Williams C; Teuscher C
Article: CARCINOGENESIS. 2013;34(7):1431-1441

Estrogen receptor β expression induces changes in the microRNA pool in human colon cancer cells.

Edvardsson K; Nguyen-Vu T; Kalasekar SM; Pontén F; Gustafsson J-Å; Williams C
Article: BREAST CANCER RESEARCH. 2013;15(3):R51

Liver × receptor ligands disrupt breast cancer cell proliferation through an E2F-mediated mechanism.

Nguyen-Vu T; Vedin L-L; Liu K; Jonsson P; Lin JZ; Candelaria NR; Candelaria LP; Addanki S; Williams C; Gustafsson J-Å; Steffensen KR; Lin C-Y
Article: MOLECULAR ENDOCRINOLOGY. 2012;26(12):1991-2003

Estrogen receptors β1 and β2 have opposing roles in regulating proliferation and bone metastasis genes in the prostate cancer cell line PC3.

Dey P; Jonsson P; Hartman J; Williams C; Ström A; Gustafsson J-Å
Article: CARCINOGENESIS. 2012;33(9):1684-1691

Interplay between AP-1 and estrogen receptor α in regulating gene expression and proliferation networks in breast cancer cells.

Dahlman-Wright K; Qiao Y; Jonsson P; Gustafsson J-Å; Williams C; Zhao C
Article: CARCINOGENESIS. 2012;33(8):1502-1511

MicroRNA-regulated gene networks during mammary cell differentiation are associated with breast cancer.

Aydoğdu E; Katchy A; Tsouko E; Lin C-Y; Haldosén L-A; Helguero L; Williams C
Journal article: CANCER RESEARCH. 2012;72(8_Supplement):547

Abstract 547: Mapping of estrogen receptor-dependent and independent signaling pathways for xeno- and phytoestrogens

Katchy AC; Pinto C; Bondesson M; Williams C
Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2012;128(3-5):145-153

Estradiol-activated estrogen receptor α does not regulate mature microRNAs in T47D breast cancer cells.

Katchy A; Edvardsson K; Aydogdu E; Williams C
Article: PLOS ONE. 2012;7(3):e32080

Knockdown of SF-1 and RNF31 affects components of steroidogenesis, TGFβ, and Wnt/β-catenin signaling in adrenocortical carcinoma cells.

Ehrlund A; Jonsson P; Vedin L-L; Williams C; Gustafsson J-Å; Treuter E
Journal article: CANCER RESEARCH. 2011;71(24_Supplement):p1-02-04-p1-02-04

P1-02-04: Estrogen Receptor beta Inhibits Breast Cancer EMT by Regulating the Expression of miR-200.

Thomas C; Gayani R; Nikolos F; Hao R; Katchy A; McCollum C; Williams C; Bondesson M; Krishnamurthy S; Esteva F; Gustafsson J-A
Article: MOLECULAR ENDOCRINOLOGY. 2011;25(8):1326-1336

The two-pore domain potassium channel KCNK5: induction by estrogen receptor alpha and role in proliferation of breast cancer cells.

Alvarez-Baron CP; Jonsson P; Thomas C; Dryer SE; Williams C
Article: MOLECULAR ENDOCRINOLOGY. 2011;25(6):969-979

Estrogen receptor β induces antiinflammatory and antitumorigenic networks in colon cancer cells.

Edvardsson K; Ström A; Jonsson P; Gustafsson J-Å; Williams C
Journal article: CANCER RESEARCH. 2011;71(8_Supplement):271

Abstract 271: Rapid regulation of ion channel KCNK5 by ERα in breast cancer cell lines MCF-7 and T47D promotes cell proliferation

Alvarez-Baron CP; Jonsson P; Dryer S; Williams C
Journal article: CANCER RESEARCH. 2009;69(24_Supplement):1162

Mammary Stem Cell-Like Gene Expression and Relation to Cancer.

Williams C; Helguero L; Edvardsson K; Haldosén L; Gustafsson J
Article: CANCER RESEARCH. 2009;69(15):6100-6106

Tumor repressive functions of estrogen receptor beta in SW480 colon cancer cells.

Hartman J; Edvardsson K; Lindberg K; Zhao C; Williams C; Ström A; Gustafsson J-A
Article: BREAST CANCER RESEARCH. 2009;11(3):R26

Gene expression in murine mammary epithelial stem cell-like cells shows similarities to human breast cancer gene expression.

Williams C; Helguero L; Edvardsson K; Haldosén L-A; Gustafsson J-A
Article: ONCOGENE. 2008;27(7):1019-1032

A genome-wide study of the repressive effects of estrogen receptor beta on estrogen receptor alpha signaling in breast cancer cells.

Williams C; Edvardsson K; Lewandowski SA; Ström A; Gustafsson J-A
Article: BMC DEVELOPMENTAL BIOLOGY. 2007;7:129

Gene array identification of Ipf1/Pdx1-/- regulated genes in pancreatic progenitor cells.

Svensson P; Williams C; Lundeberg J; Rydén P; Bergqvist I; Edlund H
Article: EXPERIMENTAL CELL RESEARCH. 2006;312(10):1798-1812

Catalog of gene expression in adult neural stem cells and their in vivo microenvironment.

Williams C; Wirta V; Meletis K; Wikström L; Carlsson L; Frisén J; Lundeberg J
Article: BMC GENOMICS. 2006;7:75

Global gene expression analyses of hematopoietic stem cell-like cell lines with inducible Lhx2 expression.

Richter K; Wirta V; Dahl L; Bruce S; Lundeberg J; Carlsson L; Williams C
Article: PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE. 2002;18(6):287-293

The mutagenic effect of ultraviolet-A1 on human skin demonstrated by sequencing the p53 gene in single keratinocytes.

Persson AE; Edström DW; Bäckvall H; Lundeberg J; Pontén F; Ros A-M; Williams C
Article: ONCOGENE. 2001;20(53):7770-7778

PATCHED and p53 gene alterations in sporadic and hereditary basal cell cancer.

Ling G; Ahmadian A; Persson A; Undén AB; Afink G; Williams C; Uhlén M; Toftgård R; Lundeberg J; Pontén F
Article: ANALYTICAL BIOCHEMISTRY. 2000;287(1):25-31

Analysis of p53 mutations in single cells obtained from histological tissue sections.

Persson AE; Ling G; Williams C; Bäckvall H; Pontén J; Pontén F; Lundeberg J
Article: AMERICAN JOURNAL OF PATHOLOGY. 1999;155(5):1467-1471

A high frequency of sequence alterations is due to formalin fixation of archival specimens.

Williams C; Pontén F; Moberg C; Söderkvist P; Uhlén M; Pontén J; Sitbon G; Lundeberg J
Article: GENE. 1999;235(1-2):103-109

Context-dependent Taq-polymerase-mediated nucleotide alterations, as revealed by direct sequencing of the ZNF189 gene: implications for mutation detection.

Odeberg J; Ahmadian A; Williams C; Uhlén M; Pontén F; Lundeberg J
Article: CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION. 1999;8(5):433-438

p53 Mutations in lung cancer associated with residential radon exposure.

Yngveson A; Williams C; Hjerpe A; Lundeberg J; Söderkvist P; Pershagen G
Article: ONCOGENE. 1998;17(14):1837-1843

Genetic instability in the 9q22.3 region is a late event in the development of squamous cell carcinoma.

Ahmadian A; Ren ZP; Williams C; Pontén F; Odeberg J; Pontén J; Uhlén M; Lundeberg J
Article: GENOMICS. 1998;50(2):213-221

Cloning and characterization of ZNF189, a novel human Krüppel-like zinc finger gene localized to chromosome 9q22-q31.

Odeberg J; Røsok O; Gudmundsson GH; Ahmadian A; Roshani L; Williams C; Larsson C; Pontén F; Uhlén M; Asheim HC; Lundeberg J
Article: CANCER RESEARCH. 1998;58(11):2449-2455

Clones of normal keratinocytes and a variety of simultaneously present epidermal neoplastic lesions contain a multitude of p53 gene mutations in a xeroderma pigmentosum patient.

Williams C; Pontén F; Ahmadian A; Ren ZP; Ling G; Rollman O; Ljung A; Jaspers NG; Uhlén M; Lundeberg J; Pontén J
Article: CLINICAL CHEMISTRY. 1998;44(3):455-462

Assessment of sequence-based p53 gene analysis in human breast cancer: messenger RNA in comparison with genomic DNA targets.

Williams C; Norberg T; Ahmadian A; Pontén F; Bergh J; Inganäs M; Lundeberg J; Uhlén M
Journal article: JOURNAL OF DERMATOLOGICAL SCIENCE. 1998;16:s145

Single-cell genetic analysis of the p%3 gene in human basal cell carcinoma(BCC)

Gao L; Ponten F; Williams C; Lundeberg J; Ponten J; Uhlen M
Journal article: JOURNAL OF DERMATOLOGICAL SCIENCE. 1998;16:s48

p53 gene mutations are common in clones of morphologically normal keratinocytes as well as in neoplastic lesions in xeroderma pigmentosum (XP)

Pontén F; Williams C; Ahmadian A; Ling G; Uhlén M; Lundeberg J; Pontén J
Article: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. 1997;382(1-2):45-55

Genomic analysis of single cells from human basal cell cancer using laser-assisted capture microscopy.

Pontén F; Williams C; Ling G; Ahmadian A; Nistér M; Lundeberg J; Pontén J; Uhlén M
Article: ONCOGENE. 1997;15(9):1059-1067

Molecular pathology in basal cell cancer with p53 as a genetic marker.

Pontén F; Berg C; Ahmadian A; Ren ZP; Nistér M; Lundeberg J; Uhlén M; Pontén J
Article: AMERICAN JOURNAL OF PATHOLOGY. 1997;150(5):1791-1803

Benign clonal keratinocyte patches with p53 mutations show no genetic link to synchronous squamous cell precancer or cancer in human skin.

Ren ZP; Ahmadian A; Pontén F; Nistér M; Berg C; Lundeberg J; Uhlén M; Pontén J
Journal article: MELANOMA RESEARCH. 1996;6(SUPPLEMENT 1):s53

Multiple p53 mutations are common in basal cell carcinoma

Pontén F; Berg C; Uhlén M; Pontén J
Article: CLINICAL CHEMISTRY. 1995;41(10):1461-1466

Direct solid-phase sequence analysis of the human p53 gene by use of multiplex polymerase chain reaction and alpha-thiotriphosphate nucleotides.

Berg C; Hedrum A; Holmberg A; Pontén F; Uhlén M; Lundeberg J
Visa fler

Alla övriga publikationer

Preprint: BIORXIV. 2023

Estrogen receptor activation remodelsTEAD1gene expression to alleviate nonalcoholic fatty liver disease

Sommerauer C; Gallardo-Dodd C; Savva C; Hases L; Birgersson M; Indukuri R; Shen J; Carravilla P; Geng K; Nørskov Søndergaard J; Ferrer-Aumatell C; Mercier G; Sezgin E; Korach-André M; Petersson C; Hagström H; Lauschke V; Archer A; Williams C; Kutter C
Review: ENDOCRINOLOGY. 2023;164(6):bqad063

ERβ in Granulosa Cell Tumors and Its Clinical Potential.

Birgersson M; Indukuri R; Antonson P; Nalvarte I; Archer A; Williams C
Conference publication: BIOPHYSICAL JOURNAL. 2023;122(3):289a

Sensing of protein and DNA complexes using solid-state nanopores

Jain S; Birgersson M; Kipen J; Jalden J; Stemme G; Niklaus F; Raja SN; Williams C; Herland A
Preprint: MEDRXIV. 2022

New primer sets to detect recent human adenovirus F41 variants in wastewater: Is it linked to the new acute hepatitis?

Perez-Zabaleta M; Williams C; Cetecioglu Z
Meeting abstract: ANNALS OF ONCOLOGY. 2022;33(7):S640

Gene expression profiles in endocrine-resistant breast cancer

Schagerholm C; Robertson S; Sifakis EG; Hases L; Williams C; Hartman J
Meeting abstract: CANCER RESEARCH. 2022;82(4):p1-07-07-p1-07-07

Endoresist: Prognostic and predictive gene profiles in endocrine-resistant breast cancers

Schagerholm C; Robertson S; Holm B; Lindberg K; Sifakis E; Hases L; Williams C; Hartman J
Preprint: SSRN ELECTRONIC JOURNAL. 2022

Long-Term SARS-CoV-2 Surveillance in the Wastewater of Stockholm: What Lessons Can Be Learned from the Swedish Perspective?

Perez-Zabaleta M; Archer A; Khatami K; Jafferali MH; Nandy P; Atasoy M; Birgersson M; Williams C; Cetecioglu Z
Conference publication: CANCER RESEARCH. 2020;80(16):2081

Intestinal estrogen receptor beta suppresses colon inflammation and tumorigenesis in both sexes

Hases L; Indukuri R; Birgersson M; Trang N-V; Lozano R; Saxena A; Hartman J; Frasor J; Gustafsson J-A; Katajisto P; Archer A; Williams C
Conference publication: CANCER RESEARCH. 2020;80(16):4085

Blocking Fra-1 sensitises triple-negative breast cancer to olaparib

Song D; He H; Sinha I; Pettersson L; Yan F; Haldosen L-A; Zhao C; Williams C
Preprint: BIORXIV. 2020

High-fat diet impacts the colon and its transcriptome in a sex-dependent manner that is modifiable by estrogens

Hases L; Archer A; Indukuri R; Birgersson M; Savva C; Korach-André M; Williams C
Preprint: RESEARCH SQUARE. 2019

Comparison of Serum Exosome Isolation Methods on Co-precipitated Free MicroRNAs

Cheng Y; Qu X; Dong Z; Zeng Q; Ma X; Jia Y; Li R; Jiang X; Williams C; Wang T; Xia W
Corrigendum: ONCOGENE. 2019;38(2):299-300

Correction: The atypical ubiquitin ligase RNF31 stabilizes estrogen receptor α and modulates estrogen-stimulated breast cancer cell proliferation.

Zhu J; Zhao C; Kharman-Biz A; Zhuang T; Jonsson P; Liang N; Williams C; Lin C-Y; Qiao Y; Zendehdel K; Strömblad S; Treuter E; Dahlman-Wright K
Review: CANCER LETTERS. 2018;438:24-31

Regulation of sex hormone receptors in sexual dimorphism of human cancers.

Zheng D; Williams C; Vold JA; Nguyen JH; Harnois DM; Bagaria SP; McLaughlin SA; Li Z
Conference publication: MOLECULAR BIOLOGY OF THE CELL. 2018;29(26)

Deep immunological profiling of the murine brain and spleen after high fat diet by CODEX multiplexed imaging.

Gnann C; Casals AM; Xu H; Kheder S; Archer A; Mulder J; Mitsios N; Williams C; Lundberg E; Ayoglu B
Conference publication: CANCER RESEARCH. 2017;77:3614

Antibody validation revises estrogen receptor beta research

Andersson S; Sundberg M; Pristovsek N; Ibrahim A; Jonsson P; Katona B; Clausson C-M; Zieba A; Ramstrom M; Soderberg O; Williams C; Asplund A
Conference publication: CANCER RESEARCH. 2017;77:5493

The cistrome of estrogen receptor beta in colorectal cancer cells

Indukuri R; Wang J; Mesmar F; Williams C
Conference publication: CANCER RESEARCH. 2017;77:4920

Inflammation and estrogen receptor beta modulate bacterial diversity of the gut

Ibrahim AF; Thomas Q; Saxena A; Williams C
Review: CANCER LETTERS. 2016;372(1):48-56

Estrogen receptor beta as target for colorectal cancer prevention.

Williams C; DiLeo A; Niv Y; Gustafsson J-Å
Conference publication: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2016;57(12)

Microarray Analysis of Vitamin D Treated Human Corneal Epithelial Cells

Reins RY; Mesmar F; Williams C; McDermott AM
Review: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2015;1849(2):142-151

Estrogen receptor signaling during vertebrate development.

Bondesson M; Hao R; Lin C-Y; Williams C; Gustafsson J-Å
Conference publication: CANCER RESEARCH. 2013;73:p4-07-12-p4-07-12

miR-206 inhibits cell migration through direct targeting of the actin-binding protein coronin 1C in triple-negative breast cancer

Wang J; Tsouko E; Jonsson P; Bergh J; Hartman J; Aydogdu E; Williams C
Review: ECANCERMEDICALSCIENCE. 2013;7:370

Oestrogen receptors in breast cancer: basic mechanisms and clinical implications.

Williams C; Lin C-Y
Conference publication: CANCER RESEARCH. 2013;73(8):4915

Estrogen receptor β is expressed within breast cancer cells with stem cell like capacity and confers endocrine sensitivity

Ma R; Govindasamy KM; Rosin G; Gustafsson J; Katchy A; Lindstrom L; Hilliges C; Viberg L; Blomqvist L; Frisell J; Williams C; Fredriksson I; Bergh J; Hartman J
Conference publication: CANCER RESEARCH. 2012;72:1207

Opposite effects on proliferation and bone metastasis genes by Estrogen Receptor B1 and Estrogen Receptor B2 in the prostate cancer cell line PC3

Dey P; Jonsson P; Hartman J; Williams C; Gustafsson J-A; Strom A
Conference publication: CANCER RESEARCH. 2011;71:p3-03-08-p3-03-08

microRNAs in Mammary Stem-Like Cells and Triple-Negative Breast Cancer; Conserved Functions and Treatment Potential.

Williams C; Aydogdu E; Katchy A; Lin C-Y; Baldosen L-A; Helguero L
Conference publication: CANCER RESEARCH. 2010;70:2076

Mammary stem cell-like miRNA expression and relation to cancer

Aydogdu E; Helguero L; Haldosen L-A; Williams CM
Conference publication: CANCER RESEARCH. 2010;70:2921

Antitumorigenic effects by ERβ in three different human colorectal cancer cell lines

Edvardsson K; Strom A; Gustafsson J-A; Williams C
Conference publication: CANCER RESEARCH. 2009;69(24):589S-590S

Mammary Stem Cell-Like Gene Expression and Relation to Cancer

Williams C; Helguero L; Edvardsson K; Haldosen L-A; Gustafsson J-A
Conference publication: MOLECULAR & CELLULAR PROTEOMICS. 2006;5(10):S233

Estrogen receptors in seminal vesicle and prostate;: Do they play a role in male fertility?

Schwend T; Imamov O; Williams C; Gustafsson J-A
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2001;117(3):815

The mutagenic effects of long-wave ultraviolet A in human skin;: Studied by analysing the p53 gene in single cells

Edström DW; Persson Å; Bäckvall H; Lundeberg J; Pontén F; Ros AM; Williams C
Conference publication: EPIDEMIOLOGY. 1999;10(4):S83

Radon and p53 mutations in lung cancer.

Yngveson A; Williams C; Hjerpe A; Lundeberg J; Söderkvist P; Pershagen G
Book chapter: SKIN CANCER AND UV RADIATION. 1997;p. 709-714

Multiple p53 Mutations are Common in Basal Cell Carcinoma

Ponten F; Berg C; Uhlen M; Ponten J
Visa fler

Forskningsbidrag

How estrogen receptors of the colon create a microenvironment that suppress carcinogenesis - for cancer prevention and treatment

Swedish Research Council

1 January 2023 - 31 December 2026
QuantumSense - Quantum Tunneling Sensing of Biomolecules for High-Throughput Decoding of DNA and RNA

Swedish Research Council

1 December 2018 - 30 November 2024
Estrogen-regulated lncRNAs as mediators of tumor-repressive functions in colon

Swedish Research Council

1 January 2018 - 31 December 2021
Elucidating the mechanism of ERbeta in colon carcinogenesis

National Cancer Institute

1 August 2013 - 31 May 2019
Epigenetic regulation in mammary stem/progenitor cells and its contribution to malignant transformation

Fundação para a Ciência e Tecnologia

15 March 2012 - 14 July 2015

Anställningar

Senior Forskare, Medicin, Huddinge, Karolinska Institutet, 2024-
Senior Forskare, Biovetenskaper och näringslära, Karolinska Institutet, 2023-2024

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