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Cecilia Williams

Professor, gäst

Publikationer

Estrogen receptor beta as target for colorectal cancer prevention
Williams C, Dileo A, Niv Y, Gustafsson JÅ
Cancer letters 2016;372(1):48-56

Expression Profiles of Estrogen-Regulated MicroRNAs in Breast Cancer Cells
Katchy A, Williams C
Methods in molecular biology (Clifton, N.J.) 2016;1366():373-93

RING finger protein 31 promotes p53 degradation in breast cancer cells
Zhu J, Zhao C, Zhuang T, Jonsson P, Sinha I, Williams C, et al
Oncogene 2016;35(15):1955-64

Vitamin D Induces Global Gene Transcription in Human Corneal Epithelial Cells: Implications for Corneal Inflammation
Reins Ry, Mesmar F, Williams C, Mcdermott Am
Investigative ophthalmology & visual science 2016;57(6):2689-98

Estrogen receptor signaling during vertebrate development
Bondesson M, Hao R, Lin Cy, Williams C, Gustafsson Ja
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS 2015;1849(2):142-51

Estrogen Receptor β2 Induces Hypoxia Signature of Gene Expression by Stabilizing HIF-1α in Prostate Cancer
Dey P, Velazquez-villegas La, Faria M, Turner A, Jonsson P, Webb P, et al
PloS one 2015;10(5):e0128239-

miR-200a inhibits migration of triple-negative breast cancer cells through direct repression of the EPHA2 oncogene
Tsouko E, Wang J, Frigo De, Aydoğdu E, Williams C
Carcinogenesis 2015;36(9):1051-60

Single-Molecule Sequencing Reveals Estrogen-Regulated Clinically Relevant lncRNAs in Breast Cancer
Jonsson P, Coarfa C, Mesmar F, Raz T, Rajapakshe K, Thompson Jf, et al
Molecular endocrinology (Baltimore, Md.) 2015;29(11):1634-45

Coexposure to Phytoestrogens and Bisphenol A Mimics Estrogenic Effects in an Additive Manner
Katchy A, Pinto C, Jonsson P, Trang Nv, Pandelova M, Riu A, et al
TOXICOLOGICAL SCIENCES 2014;138(1):21-35

Fatty acid and phospholipid biosynthetic pathways are regulated throughout mammary epithelial cell differentiation and correlate to breast cancer survival
Dória Ml, Ribeiro As, Wang J, Cotrim Cz, Domingues P, Williams C, et al
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014;28(10):4247-64

Genome-wide profiling of AP-1-regulated transcription provides insights into the invasiveness of triple-negative breast cancer
Zhao C, Qiao Y, Jonsson P, Wang J, Xu L, Rouhi P, et al
Cancer research 2014;74(14):3983-94

miR-206 inhibits cell migration through direct targeting of the actin-binding protein coronin 1C in triple-negative breast cancer
Wang J, Tsouko E, Jonsson P, Bergh J, Hartman J, Aydogdu E, et al
Molecular oncology 2014;8(8):1690-702

Profiling of estrogen-regulated microRNAs in breast cancer cells
Katchy A, Williams C
Journal of visualized experiments : JoVE 2014;(84):e51285-

Support of a bi-faceted role of estrogen receptor β (ERβ) in ERα-positive breast cancer cells
Jonsson P, Katchy A, Williams C
Endocrine-related cancer 2014;21(2):143-60

The atypical ubiquitin ligase RNF31 stabilizes estrogen receptor α and modulates estrogen-stimulated breast cancer cell proliferation
Zhu J, Zhao C, Kharman-biz A, Zhuang T, Jonsson P, Liang N, et al
Oncogene 2014;33(34):4340-51

Estrogen receptor expression induces changes in the microRNA pool in human colon cancer cells
Edvardsson K, Trang Nv, Kalasekar Sm, Ponten F, Gustafsson Ja, Williams C
CARCINOGENESIS 2013;34(7):1431-41

Liver x receptor ligands disrupt breast cancer cell proliferation through an E2F-mediated mechanism
Nguyen-vu T, Vedin Ll, Liu K, Jonsson P, Lin Jz, Candelaria Nr, et al
BREAST CANCER RESEARCH 2013;15(3):R51-

Oestrogen receptors in breast cancer: basic mechanisms and clinical implications
Williams C, Lin Cy
Ecancermedicalscience 2013;7():370-

Studies in experimental autoimmune encephalomyelitis do not support developmental bisphenol a exposure as an environmental factor in increasing multiple sclerosis risk
Krementsov Dn, Katchy A, Case Lk, Carr Fe, Davis B, Williams C, et al
Toxicological sciences : an official journal of the Society of Toxicology 2013;135(1):91-102

Estradiol-activated estrogen receptor alpha does not regulate mature microRNAs in T47D breast cancer cells
Katchy A, Edvardsson K, Aydogdu E, Williams C
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 2012;128(3-5):145-53

Estrogen Receptors beta 1 and beta 2 Have Opposing Roles in Regulating Proliferation and Bone Metastasis Genes in the Prostate Cancer Cell Line PC3
Dey P, Jonsson P, Hartman J, Williams C, Strom A, Gustafsson Ja
MOLECULAR ENDOCRINOLOGY 2012;26(12):1991-2003

Interplay between AP-1 and estrogen receptor α in regulating gene expression and proliferation networks in breast cancer cells
Dahlman-wright K, Qiao Y, Jonsson P, Gustafsson JÅ, Williams C, Zhao C
Carcinogenesis 2012;33(9):1684-91

Knockdown of SF-1 and RNF31 affects components of steroidogenesis, TGFβ, and Wnt/β-catenin signaling in adrenocortical carcinoma cells
Ehrlund A, Jonsson P, Vedin Ll, Williams C, Gustafsson JÅ, Treuter E
PloS one 2012;7(3):e32080-

MicroRNA-regulated gene networks during mammary cell differentiation are associated with breast cancer
Aydogdu E, Katchy A, Tsouko E, Lin Cy, Haldosen La, Helguero L, et al
CARCINOGENESIS 2012;33(8):1502-11

Estrogen Receptor beta Induces Antiinflammatory and Antitumorigenic Networks in Colon Cancer Cells
Edvardsson K, Strom A, Jonsson P, Gustafsson Ja, Williams C
MOLECULAR ENDOCRINOLOGY 2011;25(6):969-79

The two-pore domain potassium channel KCNK5: induction by estrogen receptor alpha and role in proliferation of breast cancer cells
Alvarez-baron Cp, Jonsson P, Thomas C, Dryer Se, Williams C
Molecular endocrinology (Baltimore, Md.) 2011;25(8):1326-36

Gene expression in murine mammary epithelial stem cell-like cells shows similarities to human breast cancer gene expression
Williams C, Helguero L, Edvardsson K, Haldosen La, Gustafsson Ja
BREAST CANCER RESEARCH 2009;11(3):R26-

Tumor repressive functions of estrogen receptor beta in SW480 colon cancer cells
Hartman J, Edvardsson K, Lindberg K, Zhao C, Williams C, Ström A, et al
Cancer research 2009;69(15):6100-6

A genome-wide study of the repressive effects of estrogen receptor beta on estrogen receptor alpha signaling in breast cancer cells
Williams C, Edvardsson K, Lewandowski Sa, Strom A, Gustafsson Ja
ONCOGENE 2008;27(7):1019-32

Gene array identification of Ipf1/Pdx1(-/-) regulated genes in pancreatic progenitor cells
Svensson P, Williams C, Lundeberg J, Ryden P, Bergqvist I, Edlund H
BMC DEVELOPMENTAL BIOLOGY 2007;:129-

Catalog of gene expression in adult neural stem cells and their in vivo microenvironment
Williams C, Wirta V, Meletis K, Wikstrom L, Carlsson L, Frisen J, et al
EXPERIMENTAL CELL RESEARCH 2006;312(10):1798-812

Estrogen receptors in seminal vesicle and prostate; Do they play a role in male fertility?
Schwend T, Imamov O, Williams C, Gustafsson Ja
MOLECULAR & CELLULAR PROTEOMICS 2006;5(10):S233-S233

Global gene expression analyses of hematopoietic stem cell-like cell lines with inducible Lhx2 expression
Richter K, Wirta V, Dahl L, Bruce S, Lundeberg J, Carlsson L, et al
BMC GENOMICS 2006;:75-

The mutagenic effect of ultraviolet-A1 on human skin demonstrated by sequencing the p53 gene in single keratinocytes
Persson Ae, Edstrom Dw, Backvall H, Lundeberg J, Ponten F, Ros Am, et al
PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE 2002;18(6):287-93

PATCHED and p53 gene alterations in sporadic and hereditary basal cell cancer
Ling G, Ahmadian A, Persson A, Unden Ab, Afink G, Williams C, et al
ONCOGENE 2001;20(53):7770-8

The mutagenic effects of long-wave ultraviolet A in human skin; Studied by analysing the p53 gene in single cells
Edstrom Dw, Persson Ae, Backvall H, Lundeberg J, Ponten F, Ros Am, et al
JOURNAL OF INVESTIGATIVE DERMATOLOGY 2001;117(3):815-815

Analysis of p53 mutations in single cells obtained from histological tissue sections
Persson Ae, Ling G, Williams C, Backvall H, Ponten J, Ponten F, et al
ANALYTICAL BIOCHEMISTRY 2000;287(1):25-31

A high frequency of sequence alterations is due to formalin fixation of archival specimens
Williams C, Ponten F, Moberg C, Soderkvist P, Uhlen M, Ponten J, et al
AMERICAN JOURNAL OF PATHOLOGY 1999;155(5):1467-71

Context-dependent Taq-polymerase-mediated nucleotide alterations, as revealed by direct sequencing of the ZNF189 gene: implications for mutation detections
Odeberg J, Ahmadian A, Williams C, Uhlen M, Ponten F, Lundeberg J
GENE 1999;235(1-2):103-9

p53 mutations in lung cancer associated with residential radon exposure
Yngveson A, Williams C, Hjerpe A, Lundeberg J, Soderkvist P, Pershagen G
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 1999;8(5):433-8

Radon and p53 mutations in lung cancer.
Yngveson A, Williams C, Hjerpe A, Lundeberg J, Soderkvist P, Pershagen G
EPIDEMIOLOGY 1999;10(4):S83-S83

Assessment of sequence-based p53 gene analysis in human breast cancer: messenger RNA in comparison with genomic DNA targets
Williams C, Norberg T, Ahmadian A, Ponten F, Bergh J, Inganas M, et al
CLINICAL CHEMISTRY 1998;44(3):455-62

Clones of normal keratinocytes and a variety of simultaneously present epidermal neoplastic lesions contain a multitude of p53 gene mutations in a xeroderma pigmentosum patient
Williams C, Ponten F, Ahmadian A, Ren Zp, Ling G, Rollman O, et al
CANCER RESEARCH 1998;58(11):2449-55

Cloning and characterization of ZNF189, a novel human Kruppel-like zinc finger gene localized to chromosome 9q22-q31
Odeberg J, Rosok O, Gudmundsson Gh, Ahmadian A, Roshani L, Williams C, et al
GENOMICS 1998;50(2):213-21

Genetic instability in the 9q22.3 region is a late event in the development of squamous cell carcinoma
Ahmadian A, Ren Zp, Williams C, Ponten F, Odeberg J, Ponten J, et al
ONCOGENE 1998;17(14):1837-43

Single-cell genetic analysis of the p53 gene in human basal cell carcinoma (BCC)
Gao L, Ponten F, Williams C, Lundeberg J, Ponten J
JOURNAL OF INVESTIGATIVE DERMATOLOGY 1998;110(4):616-616

Benign clonal keratinocyte patches with p53 mutations show no genetic link to synchronous squamous cell precancer or cancer in human skin
Ren Zp, Ahmadian A, Ponten F, Nister M, Berg C, Lundeberg J, et al
AMERICAN JOURNAL OF PATHOLOGY 1997;150(5):1791-803

Genomic analysis of single cells from human basal cell cancer using laser-assisted capture microscopy
Ponten F, Williams C, Ling G, Ahmadian A, Nister M, Lundeberg J, et al
MUTATION RESEARCH-GENOMICS 1997;382(1-2):45-55

Molecular pathology in basal cell cancer with p53 as a genetic marker
Ponten F, Berg C, Ahmadian A, Ren Zp, Nister M, Lundeberg J, et al
ONCOGENE 1997;15(9):1059-67

Multiple p53 mutations are common in basal cell carcinoma
Ponten F, Berg C, Uhlen M, Ponten J
JOURNAL OF INVESTIGATIVE DERMATOLOGY 1996;106(4):295-295

DIRECT SOLID-PHASE SEQUENCE-ANALYSIS OF THE HUMAN P53 GENE BY USE OF MULTIPLEX POLYMERASE CHAIN-REACTION AND ALPHA-THIOTRIPHOSPHATE NUCLEOTIDES
Berg C, Hedrum A, Holmberg A, Ponten F, Uhlen M, Lundeberg J
CLINICAL CHEMISTRY 1995;41(10):1461-6

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