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Maj Hulten

Forskare

Besöksadress : Trolldaslvagen 37, Trolldalen, 18129 Lidingo
Leveransadress : Trolldaslvagen 37, Trolldalen, 18129 Lidingo

Publikationer

Disomy 21 in spermatozoa and the paternal origin of trisomy 21 Down syndrome
Iwarsson E, Kvist U, Hultén Ma
Molecular cytogenetics 2015;8():67-

Maternal Germinal Trisomy 21 in Down Syndrome
Hultén Ma, Öijerstedt L, Iwarsson E, Jonasson J
Journal of clinical medicine 2014;3(1):167-75

Trisomy 21 mosaicism: we may all have a touch of Down syndrome
Hultén Ma, Jonasson J, Iwarsson E, Uppal P, Vorsanova Sg, Yurov Yb, et al
Cytogenetic and genome research 2013;139(3):189-92

Comment on "Origin of trisomy: no evidence to support the ovarian mosaicism theory"
Hulten Ma, Jonasson J, Westgren M, Jonsson Am, Papadogiannakis N, Iwarsson E
Prenatal diagnosis 2012;32(12):1221-

MECP2 gene mutation analysis in the British and Italian Rett Syndrome patients: hot spot map of the most recurrent mutations and bioinformatic analysis of a new MECP2 conserved region (vol 23, pg S246, 2011)
Vacca M, Filippini F, Budillon A, Rossi V, Della Ragione F, De Bonis Ml, et al
BRAIN & DEVELOPMENT 2012;34(10):891-891

On the origin of crossover interference: A chromosome oscillatory movement (COM) model
Hultén Ma
Molecular cytogenetics 2011;4():10-

Differential DNA Methylation as a Tool for Noninvasive Prenatal Diagnosis (NIPD) of X Chromosome Aneuploidies
Della Ragione F, Mastrovito P, Campanile C, Conti A, Papageorgiou Ea, Hulten Ma, et al
JOURNAL OF MOLECULAR DIAGNOSTICS 2010;12(6):797-807

Germinal and Somatic Trisomy 21 Mosaicism: How Common is it, What are the Implications for Individual Carriers and How Does it Come About?
Hultén Ma, Jonasson J, Nordgren A, Iwarsson E
Current genomics 2010;11(6):409-19

On the origin of the maternal age effect in trisomy 21 Down syndrome: the Oocyte Mosaicism Selection model
Hultén Ma, Patel S, Jonasson J, Iwarsson E
Reproduction (Cambridge, England) 2010;139(1):1-9

On the paternal origin of trisomy 21 Down syndrome
Hultén Ma, Patel Sd, Westgren M, Papadogiannakis N, Jonsson Am, Jonasson J, et al
Molecular cytogenetics 2010;3():4-

Non-invasive prenatal diagnosis: another new concept in need of a definition
Hulten M
REPRODUCTIVE BIOMEDICINE ONLINE 2009;19(5):756-

Novel rare alleles of ABCA1 are exclusively associated with extreme high-density lipoprotein-cholesterol levels among the Han Chinese
Hu Sw, Zhong Yf, Hao Yt, Luo Mq, Zhou Y, Guo H, et al
CLINICAL CHEMISTRY AND LABORATORY MEDICINE 2009;47(10):1239-45

Sites of Differential DNA Methylation between Placenta and Peripheral Blood Molecular Markers for Noninvasive Prenatal Diagnosis of Aneuploidies
Papageorgiou Ea, Fiegler H, Rakyan V, Beck S, Hulten M, Lamnissou K, et al
AMERICAN JOURNAL OF PATHOLOGY 2009;174(5):1609-18

On the origin of trisomy 21 Down syndrome
Hultén Ma, Patel Sd, Tankimanova M, Westgren M, Papadogiannakis N, Jonsson Am, et al
Molecular cytogenetics 2008;1():21-

Candidate epigenetic biomarkers for non-invasive prenatal diagnosis of Down syndrome
Old Rw, Crea F, Puszyk W, Hulten Ma
REPRODUCTIVE BIOMEDICINE ONLINE 2007;15(2):227-35

Non-invasive prenatal diagnosis of Down's syndrome
Hulten Ma, Old Rw
LANCET 2007;369(9578):1997-author

Workshop report on the extraction of foetal DNA from maternal plasma
Legler Tj, Liu Z, Mavrou A, Finning K, Hromadnikova I, Galbiati S, et al
PRENATAL DIAGNOSIS 2007;27(9):824-9

Altered patterns of meiotic recombination in human fetal oocytes with asynapsis and/or synaptonemal complex fragmentation at pachytene
Hulten M
REPRODUCTIVE BIOMEDICINE ONLINE 2006;13(1):88-95

Increased skewing of X chromosome inactivation in Rett syndrome patients and their mothers
Knudsen Gps, Neilson Tcs, Pedersen J, Kerr A, Schwartz M, Hulten M, et al
EUROPEAN JOURNAL OF HUMAN GENETICS 2006;14(11):1189-94

The X-linked methyl binding protein gene Kaiso is highly expressed in brain but is not mutated in Rett syndrome patients
Della Ragione F, Tiunova A, Vacca M, Strazzullo M, Gonzalez E, Armstrong J, et al
GENE 2006;:83-9

Dimensional phenotypic analysis and functional categorisation of mutations reveal novel genotype-phenotype associations in Rett syndrome
Charman T, Neilson Tc, Mash V, Archer H, Gardiner Mt, Knudsen Gps, et al
EUROPEAN JOURNAL OF HUMAN GENETICS 2005;13(10):1121-30

DNMT3B mutations and DNA methylation defect define two types of ICF syndrome
Jiang Yl, Rigolet M, Bourc'his D, Nigon F, Bokesoy I, Fryns Jp, et al
HUMAN MUTATION 2005;25(1):56-63

Large genomic rearrangements in MECP2
Ravn K, Nielsen Jb, Skjeldal Oh, Kerr A, Hulten M, Schwartz M
Human mutation 2005;25(3):324-

An excess of chromosome 1 breakpoints in male infertility
Bache I, Assche Ev, Cingoz S, Bugge M, Tümer Z, Hjorth M, et al
European journal of human genetics : EJHG 2004;12(12):993-1000

Glycophorin A somatic cell mutations in a population living in the proximity of the Semipalatinsk nuclear test site
Lindholm C, Murphy Bp, Bigbee Wl, Bersimbaev Ri, Hulten Ma, Dubrova Ye, et al
RADIATION RESEARCH 2004;162(2):164-70

Inter-sex variation in synaptonemal complex lengths largely determine the different recombination rates in male and female germ cells
Tease C, Hulten Ma
CYTOGENETIC AND GENOME RESEARCH 2004;107(3-4):208-15

The initiation of homologous chromosome synapsis in mouse fetal oocytes is not directly driven by centromere and telomere clustering in the bouquet
Tankimanova M, Hulten Ma, Tease C
CYTOGENETIC AND GENOME RESEARCH 2004;105(2-4):172-81

Evaluation of molecular tests for prenatal diagnosis of chromosome abnormalities
Grimshaw Gm, Szczepura A, Hultén M, Macdonald F, Nevin Nc, Sutton F, et al
Health technology assessment (Winchester, England) 2003;7(10):1-146

Rapid and simple prenatal diagnosis of common chromosome disorders: advantages and disadvantages of the molecular methods FISH and QF-PCR
Hulten Ma, Dhanjal S, Pertl B
REPRODUCTION 2003;126(3):279-97

Growth factors promote meiosis in mouse fetal ovaries in vitro
Lyrakou S, Hulten Ma, Hartshorne Gm
MOLECULAR HUMAN REPRODUCTION 2002;8(10):906-11

Meiotic chromosome pairing in fetal oocytes of trisomy 21 human females
Barlow Al, Tease C, Hulten Ma
CYTOGENETIC AND GENOME RESEARCH 2002;96(1-4):45-51

Nuclear weapons tests and human germline mutation rate
Dubrova Ye, Bersimbaev Ri, Djansugurova Lb, Tankimanova Mk, Mamyrbaeva Zz, Mustonen R, et al
SCIENCE 2002;295(5557):1037-

Numbers, bands and recombination of human chromosomes: Historical anecdotes from a Swedish student
Hulten Ma
CYTOGENETIC AND GENOME RESEARCH 2002;96(1-4):14-9

Patterns of meiotic recombination in human fetal oocytes
Tease C, Hartshorne Gm, Hulten Ma
AMERICAN JOURNAL OF HUMAN GENETICS 2002;70(6):1469-79

Stable chromosome aberrations in the lymphocytes of a population living in the vicinity of the Semipalatinsk nuclear test site
Salomaa S, Lindholm C, Tankimanova Mk, Mamyrbaeva Zz, Koivistoinen A, Hulten M, et al
RADIATION RESEARCH 2002;158(5):591-6

Automatic signal classification in fluorescence in situ hybridization images
Lerner B, Clocksin Wf, Dhanjal S, Hulten Ma, Bishop Cm
CYTOMETRY 2001;43(2):87-93

Feature representation and signal classification in fluorescence in-situ hybridization image analysis
Lerner B, Clocksin Wf, Dhanjal S, Hulten Ma, Bishop Cm
IEEE TRANSACTIONS ON SYSTEMS MAN AND CYBERNETICS PART A-SYSTEMS AND HUMANS 2001;31(6):655-665

GELFISH - Graphical environment for labelling fluorescence in-situ hybridization images
Lerner B, Dhanjal S, Hulten Ma
JOURNAL OF MICROSCOPY-OXFORD 2001;:258-68

MECP2 gene mutation analysis in the British and Italian Rett Syndrome patients: hot spot map of the most recurrent mutations and bioinformatic analysis of a new MECP2 conserved region
Vacca M, Filippini F, Budillon A, Rossi V, Della Ragione F, De Bonis Ml, et al
BRAIN & DEVELOPMENT 2001;:S246-50

Mutation analysis of the MECP2 gene in British and Italian Rett syndrome females
Vacca M, Filippini F, Budillon A, Rossi V, Mercadante G, Manzati E, et al
JOURNAL OF MOLECULAR MEDICINE-JMM 2001;78(11):648-55

Non-invasive prenatal diagnosis of Down's syndrome
Hulten M
LANCET 2001;357(9260):963-4

Long-read sequence analysis of the MECP2 gene in Rett syndrome patients: correlation of disease severity with mutation type and location
Cheadle Jp, Gill H, Fleming N, Maynard J, Kerr A, Leonard H, et al
HUMAN MOLECULAR GENETICS 2000;9(7):1119-29

Long-read sequence analysis of the MECP2 gene in Rett syndrome patients: correlation of disease severity with mutation type and location (vol 9, pg 1119, 2000)
Cheadle Jp, Gill H, Fleming N, Maynard J, Kerr A, Leonard H, et al
HUMAN MOLECULAR GENETICS 2000;9(11):1717-1717

Mammalian meiotic telomeres: Protein composition and redistribution in relation to nuclear pores
Scherthan H, Jerratsch M, Li Bb, Smith S, Hulten M, Lock T, et al
MOLECULAR BIOLOGY OF THE CELL 2000;11(12):4189-203

Meiotic studies of a human male carrier of the common translocation, t(11;22), suggests postzygotic selection rather than preferential 3 : 1 MI segregation as the cause of liveborn offspring with an unbalanced translocation
Armstrong Sj, Goldman Ash, Speed Rm, Hulten Ma
AMERICAN JOURNAL OF HUMAN GENETICS 2000;67(3):601-9

Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene
Xu Gl, Bestor Th, Bourc'his D, Hsieh Cl, Tommerup N, Bugge M, et al
NATURE 1999;402(6758):187-91

Immunocytogenetic detection of normal and abnormal oocytes in human fetal ovarian tissue in culture
Hartshorne Gm, Barlow Al, Child Tj, Barlow Dh, Hulten Ma
HUMAN REPRODUCTION 1999;14(1):172-82

Combined immunocytogenetic and molecular cytogenetic analysis of meiosis I oocytes from normal human females
Barlow Al, Hulten Ma
ZYGOTE 1998;6(1):27-38

Crossing over analysis at pachytene in man
Barlow Al, Hulten Ma
EUROPEAN JOURNAL OF HUMAN GENETICS 1998;6(4):350-8

Genetic analysis of meiotic recombination in humans by use of sperm typing: Reduced recombination within a heterozygous paracentric inversion of chromosome 9q32-q34.3
Brown Gm, Leversha M, Hulten M, Ferguson-smith Ma, Affara Na, Furlong Ra
AMERICAN JOURNAL OF HUMAN GENETICS 1998;62(6):1484-92

Meiotic segregation analysis by FISH investigations in sperm and spermatocytes of translocation heterozygotes
Armstrong Sj, Hulten Ma
EUROPEAN JOURNAL OF HUMAN GENETICS 1998;6(5):430-1

Prenatal DNA diagnosis of Down's syndrome by PCR - Reply
Hulten Ma, Szczepura A
LANCET 1998;352(9132):990-990

Rapid and simple prenatal DNA diagnosis of Down's syndrome
Verma L, Macdonald F, Leedham P, Mcconachie M, Dhanjal S, Hulten M
LANCET 1998;352(9121):9-12

Analysis of proximal X chromosome pairing in early female mouse meiosis
Okeeffe C, Hulten Ma, Tease C
CHROMOSOMA 1997;106(5):276-83

Childhood cancer and parental use of tobacco: Deaths from 1953 to 1955
Sorahan T, Lancashire Rj, Hulten Ma, Peck I, Stewart Am
BRITISH JOURNAL OF CANCER 1997;75(1):134-8

Childhood cancer and parental use of tobacco: deaths from 1971 to 1976
Sorahan T, Prior P, Lancashire Rj, Faux Sp, Hulten Ma, Peck Im, et al
BRITISH JOURNAL OF CANCER 1997;76(11):1525-31

Different strategies of X-inactivation in germinal and somatic cells: Histone H4 underacetylation does not mark the inactive X chromosome in the mouse male germline
Armstrong Sj, Hulten Ma, Keohane Am, Turner Bm
EXPERIMENTAL CELL RESEARCH 1997;230(2):399-402

Distribution of the Rad51 recombinase in human and mouse spermatocytes
Barlow Al, Benson Fe, West Sc, Hulten Ma
EMBO JOURNAL 1997;16(17):5207-15

Human T-cell receptor zeta chain gene Map position 1q23.1
Stacey M, Barlow A, Hulten M
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 1997;5(4):279-

Sequential immunocytogenetics, molecular cytogenetics and transmission electron microscopy of microspread meiosis I oocytes from a human fetal carrier of an unbalanced translocation
Barlow Al, Hulten Ma
CHROMOSOMA 1997;106(5):293-303

Study of Alu sequences at the hypoxanthine phosphoribosyltransferase (hprt) encoding region of man
Renwick Pj, Birley Aj, Hulten Ma
GENE 1997;184(2):155-62

Analysis of lymphocytes from uranium mineworkers in Namibia for chromosomal damage using Fluorescence in situ hybridization (FISH)
Zaire R, Griffin Cs, Simpson Pj, Papworth Dg, Savage Jrk, Armstrong S, et al
MUTATION RESEARCH-GENETIC TOXICOLOGY 1996;371(1-2):109-13

Combined immunocytogenetic and molecular cytogenetic analysis of meiosis I human spermatocytes
Barlow Al, Hulten Ma
CHROMOSOME RESEARCH 1996;4(8):562-73

Jubilee human chromosomes
Hulten M
TRENDS IN GENETICS 1996;12(12):533-534

ATP-DEPENDENT REORGANIZATION OF HUMAN SPERM NUCLEAR CHROMATIN
Banerjee S, Smallwood A, Hulten M
JOURNAL OF CELL SCIENCE 1995;:755-65

CHIASMA-BASED GENETIC-MAP OF THE MOUSE X-CHROMOSOME
Hulten Ma, Tease C, Lawrie Nm
CHROMOSOMA 1995;104(3):223-7

CHIASMA FREQUENCY, DISTRIBUTION AND INTERFERENCE MAPS OF MOUSE AUTOSOMES
Lawrie Nm, Tease C, Hulten Ma
CHROMOSOMA 1995;104(4):308-14

DOES JUNK DNA REGULATE GENE-EXPRESSION IN HUMANS
Hulten Ma, Stacey M, Armstrong Sj
JOURNAL OF CLINICAL PATHOLOGY-CLINICAL MOLECULAR PATHOLOGY EDITION 1995;48(3):M118-23

FISH ANALYSIS ON SPONTANEOUSLY ARISING MICRONUCLEI IN THE ICF SYNDROME
Stacey M, Bennett Ms, Hulten M
JOURNAL OF MEDICAL GENETICS 1995;32(7):502-8

MOLECULAR VARIATION OF THE HUMAN ELASTIN (ELN) GENE IN A NORMAL HUMAN-POPULATION
Raybould Mc, Birley Aj, Hulten M
ANNALS OF HUMAN GENETICS 1995;:149-61

SOUTHERN ANALYSIS REVEALS A LARGE DELETION AT THE HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE LOCUS IN A PATIENT WITH LESCH-NYHAN SYNDROME
Renwick Pj, Birley Aj, Mckeown Cme, Hulten M
CLINICAL GENETICS 1995;48(2):80-4

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