Doktorsavhandlingar vid OnkPat

2024

4. Pedro Fonseca
Using the force: Targeting p60AmotL2-mediated invasion in cancer
18 april 2024
Abstract och ramberättelse

3. Anders Lideståhl
Radiation-induced toxicity and secondary malignant neoplasms in radiotherapy of intrathoracic tumors
22 mars 2024
Abstract och ramberättelse

2. Smaranda Bacanu
The cellular thermal shift assay (CETSA) for elucidating drug mechanism of action and resistance in cancer
15 mars 2024
Abstract och ramberättelse

1. Yumeng Zhang
Exploring signaling pathways in endothelial mechanotransduction
13 februari 2024
Abstract och ramberättelse

2023

17. Yanhong Su
Sarcoma ecosystems: spatial characterization and prognostic significance
8 december 2023
Abstract och ramberättelse

16. Apple Tay
Art of tumor immunity: extricating hypoxia-driven immunosuppression in the solid tumor microenvironment
27 oktober 2023
Abstract och ramberättelse

15. Angelos Heldin
Pharmacological targeting of nonsense mutant TP53 and PTEN in cancer
20 oktober 2023
Abstract och ramberättelse

14. Petra Marttila
Targeting MTHFD1 and MTHFD2 as cancer treatment
20 oktober 2023
Abstract och ramberättelse

13. Sandra Wessman
Precision medicine of ovarian cancer for adults and children: molecular, hereditary and clinical aspects
28 september 2023
Abstract och ramberättelse

12. Huma Dar
Long-term risk for fatal and distant metastatic disease in women with ER-positive breast cancer
15 september 2023
Abstract och ramberättelse

11. Haris Babačić
Discovering circulating protein biomarkers through in-depth plasma proteomics
20 juni 2023
Abstract och ramberättelse

10. Nathanael Andrews
Clonal structures and cell interactions in cancer
20 juni 2023
Abstract och ramberättelse

9. Mirco Martino
The odyssey of MYC transcript from the nucleus to the cytoplasm: the molecular mechanism of the gene gating in human cancer cells
16 juni 2023
Abstract och ramberättelse

8. Mark Zupancic
Diagnostic and prognostic markers in primarily non-smoking related head and neck cancer
16 juni 2023
Abstract och ramberättelse

7. Mattie Salim
Deep learning algorithms for tumor detection in screening mammography
2 juni 2023
Abstract och ramberättelse

6. Martin Harper Hysek
Telomerase related studies in thyroid cancer
12 maj 2023
Abstract och ramberättelse

5. Meis Omran
Heritable TP53-related cancer syndrome in Sweden: Characterisation of genotype-phenotype correlation and surveillance
5 maj 2023
Abstract och ramberättelse

4. Anna Embring
Radiotherapy in advanced head and neck cancer
21 april 2023
Abstract och ramberättelse

3. Stefanie Marie Renken
Evaluating antitumoral lymphocytes for adoptive cell therapy: oxidative stress, neoantigen processing and co-stimulation
14 april 2023
Abstract och ramberättelse

2. Mireia Palomar Siles
Translational readthrough of nonsense mutant TP53, RB1 and PTEN tumor suppressor genes as a strategy for novel cancer therapy
31 mars 2023
Abstract och ramberättelse

1. Masoud Karimi
Prognostic and predictive factors for colorectal cancer
10 februari 2023
Abstract och ramberättelse

2022

21. Ioannis Siavelis
Cancer proteogenomics: connecting genotype to molecular phenotype
16 december 2022
Abstract och ramberättelse

20. Oana-Sonia Cismas
When the bear lost its tail: targeting the GRK/β-arrestins downstream IGF1R in non-epithelial malignancies 
16 december 2022
Abstract och ramberättelse

19. Marie Hjälm-Eriksson
Long-term oncological outcome and health-related quality of life after curative treatment of prostate cancer with HDR-brachytherapy and external beam radiotherapy
18 november 2022
Abstract och ramberättelse

18. Esther Schoutrop
Defining the potential of mesothelin-directed CAR T cells for the treatment of ovarian cancer
21 oktober 2022
Abstract och ramberättelse

17. Johanna Vestlund
Beyond transcription: A post-transcriptional role of 3D chromatin crosstalk in oncogene regulation
3 oktober 2022
Abstract och ramberättelse

16. Mehdi Astaraki
Advanced machine learning methods for oncological image analysis
30 september 2022
Abstract och ramberättelse

15. Yifan Zhang
Morphologic and genetic features of sarcomas: improving diagnosis and exploring biomarkers
23 september 2022
Abstract och ramberättelse

14. Yaxuan Liu
Evaluation of genetic cancer predisposition and potential cancer genes
20 juni 2022
Abstract och ramberättelse

13. Luisa Edman Kessler
Investigating the treatment of metastatic breast cancer: real-world evidence on treatment patterns, safety and efficacy
17 juni 2022
Abstract och ramberättelse

12. Andreas Ährlund-Richter
Studies on human papillomavirus (HPV) and other markers in the development and prognosis of HPV associated cancer
14 juni 2022
Abstract och ramberättelse

11. Claes Lindh
Morphological, immunohistochemical and genetic aspects of acinar and ductal adenocarcinoma of the prostate
31 maj 2022
Abstract och ramberättelse

10. Alexandra Grahn
Current and possible future diagnostic methods for upper tract urothelial carcinoma
20 maj 2022
Abstract och ramberättelse

9. Jiwei Gao
Dissecting the roles of viral T-antigens in Merkel cell carcinoma
6 maj 2022
Abstract och ramberättelse

8. Camilla Malm
Upper tract urothelial carcinoma - diagnostic and prognostic factors
29 april 2022
Abstract och ramberättelse

7. Khang Luu
Immunoregulatory properties of CD137-CD137 ligand axis in tumours and chronic inflammatory conditions
4 april 2022
Abstract och ramberättelse

6. Emma Jussing
Development of radiometal-based labelling techniques and tracers for non-invasive molecular imaging
25 mars 2022
Abstract och ramberättelse

5. Yi Chen
Genetic and molecular mechanisms of sarcomas
4 mars 2022
Abstract och ramberättelse

4. Ilias Tzelepis
Regulation of MYC transcription in 3D: Implications for tumor development
25 februari 2022
Abstract och ramberättelse

3. Dawei Song
Old receptors learn new tricks: biasing anti-IGF1R cancer therapy through the GPCR system
25 februari 2022
Abstract och ramberättelse

2. Tom Mulder
Immune cells in chronic lymphocytic leukemia and Hodgkin lymphoma in relation to tumor burden and treatment
25 februari 2022
Abstract och ramberättelse

1. Johannes Ristau
Untangling the contribution of untranslated regions to mRNA translation in health and disease
11 februari 2022
Abstract och ramberättelse

2021

29. Muyi Yang
Molecular biomarkers in melanoma susceptibility and therapy response
21 december 2021
Abstract och ramberättelse

28. Stella Karsten
The DNA repair enzymes MTH1 and OGG1 as targets to treat inflammation
17 december 2021
Abstract och ramberättelse 

27. Ninni Mu
Diagnostic and prognostic markers in thyroid carcinoma with focus on TERT activation
16 december 2021
Abstract och ramberättelse

26. Fabio Socciarelli
At the intersection of proteomics and pathology: application of mass spectrometry-based protein quantification to histopathology and antibody validation
10 december 2021
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25. Amineh Ghaderi
ROR1 − a druggable target: preclinical studies of ROR1 and combinatorial partners in malignancies
3 december 2021
Abstract och ramberättelse

24. Shi Yong Neo
Uniquely NK cells: The multifaceted roles of the natural killers
3 december 2021
Abstract och ramberättelse

23. Xia Hao
Novel in vitro methods aiming at improving fertility preservation
2 december 2021
Abstract och rämberättelse

22. Gry Johansen
Fertility-sparing surgery in young women with ovarian cancer and borderline ovarian tumors
12 november 2021
Abstract och ramberättelse

21. Bishoy Hanna
Modulating the activity of OGG1 using small molecules to target the oxidative DNA damage response in cancer and inflammation
26 oktober 2021
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20. Taner Arslan
Deciphering the complexity of biological systems using machine learning applied to big data
22 oktober 2021
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19. Lucy Bai
Long-term follow-up after risk-reducing mastectomy and immediate breast reconstruction - from a patient, partner, and 3D perspective
1 oktober 2021
Abstract och ramberättelse

18. Yasmin Désirée Yu
Autophagy and VPS34 as targets in anti-cancer therapy
10 september 2021
Abstract och ramberättelse

17. Johan Paulsson
Genetic and molecular characterization of follicular thyroid tumors - diagnostic and prognostic aspects
10 september 2021
Abstract och ramberättelse

16. Hui Liu
Exploring mTOR-dependent regulation of mRNA translation in cancer
23 juni 2021
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15. Jemina Lehto
Finding synergies for cancer treatment: new ways to modulate DNA damage repair by CX3CR1 and PFKFB3 inhibition
23 juni 2021
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14. Anna Huguet Ninou
Emerging roles of PFKFB3 and CX3CR1 in the DNA damage response and their potential as therapeutic targets in cancer
23 juni 2021
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13. Nadilly Bonagas Villarreal
Exploring novel roles of metabolic enzymes MTHFD2 and PFKFB3 in cancer genome stability and their potential as anticancer therapeutic targets
4 juni 2021
Abstract och ramberättelse

12. Daniela Swanberg
Assessment of prognostic factors of prostate cancer - Limitations and possibilities of morphology
31 maj 2021
Abstract och ramberättelse

11. Marianna Tampere
Advancing antiviral strategies against emerging RNA viruses by phenotypic drug discovery
21 maj 2021
Abstract och ramberättelse

10. Aleksandra Pettke
Cell and organoid models to develop new antivirals and diagnostic methods for emerging viruses
7 maj 2021
Abstract och ramberättelse

9. Denis Nastic
Improving endometrial carcinoma diagnostics
27 april 2021
Abstract och ramberättelse

8. Christian Oertlin
Developing analytical tools to investigate the role of translation in homeostasis and disease
23 april 2021
Abstract och ramberättelse

7. Ziqing Chen
From natural to eximious: harnessing the power of natural killer cells against solid tumors
23 april 2021
Abstract och ramberättelse

6. Fernanda Costa Svedman
Molecular markers for prediction of response and progression free survival to novel therapies in cutaneous malignant melanoma
19 mars 2021
Abstract och ramberättelse

5. Sophia Ceder
Mechanisms of cancer cell death by mutant p53-reactivating compound APR-246
5 mars 2021
Abstract och ramberättelse

4. Anna Lewandowska Ronnegren
Crosstalk between environmental signals and 3d genome organization in the regulation of gene expression
12 februari 2021
Abstract och ramberättelse

3. Angeliki Karambatsakidou
Radiation dose and related risk in interventional cardiology
29 januari 2021
Abstract och ramberättelse

2. Anna Marklund
Assisted reproductive technologies for fertility preservation and fertility treatment in young women with cancer
22 januari 2021
Abstract och ramberättelse

1. Fredrika Svahn
Tumors of the adrenal glands: genetic and diagnostic aspects
15 januari 2021
Abstract och ramberättelse

2020

22. Per Fürst
Low-dose methadone as add-on to ongoing opioid treatment in cancer-related pain
11 december 2020
Abstract och ramberättelse

21. Georgios Tsakonas
Biomarkers for CNS metastasis in Non-Small Cell Lung Cancer (NSCLC)
11 december 2020
Abstract och ramberättelse

20. Anna Asklid
Real-world studies on B-cell malignancies
11 december 2020
Abstract och ramberättelse

19. Artur Omar
Radiation dose and x-ray beam modelling in diagnostic and interventional radiology using Monte Carlo methods
24 november 2020
Abstract och ramberättelse

18. Karin Holmsten
Improving chemotherapy in advanced urothelial cancer: Real-world data studies and prospective clinical trials
20 november 2020
Abstract och ramberättelse

17. Hao Shi
Regulation of cellular degradation pathways by viral oncoproteins and microRNAs
30 oktober 2020
Abstract och ramberättelse

16. Maria Wolodarski
Immunological alterations, therapies with immune check-point inhibitors and beyond in patients with metastatic melanoma
30 oktober 2020
Abstract och ramberättelse

15. Emarndeena Haji Cheteh
p53 and cancer-associated fibroblasts: implications for cancer therapy and drug resistance 
26 oktober 2020
Abstract och ramberättelse

14. Stephanie Robertson
Improving biomarker assessment in breast pathology
2 oktober 2020
Abstract och ramberättelse

13. Wen-Kuan Huang
microRNA and energy metabolism in gastrointestinal tumors
30 september 2020
Abstract och ramberättelse

12. Marie Koitsalu
Individualized prostate cancer testing- Men's views on participation
11 september 2020
Abstract och ramberättelse

11. Min Guo
Intratumoral heterogeneity in glioblastoma: subtype transition and cell-to-cell communication
28 augusti 2020
Abstract och ramberättelse

10. Yan Zhou Tran
Understanding the response to EGFR targeting therapy in non-small-cell lung cancer using -omics approach
14 augusti 2020
Abstract och ramberättelse

9. Elin Hardell
Prognosis based classification and tumor biology of uterine sarcomas
5 juni 2020
Abstract och ramberättelse

8. Ishani Das
Hitting the right targets: A study of molecular mediators of sensitivity to novel potential targeted therapies in cutaneous malignant melanoma
25 maj 2020
Abstract och ramberättelse

7. Maria Winqvist
Targeted therapy in chronic lymphocytic leukemia
20 maj 2020
Abstract och ramberättelse

6. Ioannis Zerdes
Tumor-infiltrating lymphocytes and the PD-L1/PD-1 signaling axis in breast cancer: biology and clinical implications
24 april 2020
Abstract och ramberättelse

5. Andri Papakonstantinou
Studies of side effects related to adjuvant breast cancer regimens with focus on chemotherapy
17 april 2020
Abstract och ramberättelse

4. Alessandro Mega
Astrocytes in glioblastoma: enhancers of tumor growth, predictors of patient survival and potential therapeutic targets
13 mars 2020
Abstract och ramberättelse

3. Salomon Tendler
Investigation of small-cell lung cancer epidemiology in Sweden and analysis of clinical and tumor specific prognostic biomarkers
6 mars 2020
Abstract och ramberättelse

2. Julie Lorent
Coordination of gene expression programs
14 februari 2020
Abstract och ramberättelse

1. Yuanyuan Zhang
Ready to pull: force transmission during vascular development
17 januari 2020
Abstract och ramberättelse

2019

14. Honglei Zhao
Regulation of chromatin transitions in the 3D architecture of the nucleus
18 december 2019
Abstract och ramberättelse

13. Jason Serviss
Long non-coding RNAs and cellular interactions: investigating underlying mechanisms of oncogenesis
27 november 2019
Abstract och ramberättelse

12. Mia Karlberg
Prognostic factors in colorectal cancer: studies of thymidylate synthase expression, mismatch repair protein expression, tumor budding and t-cell infiltration
25 oktober 2019
Abstract och ramberättelse

11. Satendra Kumar
Connecting viral oncoproteins to microRNA, autophagy and metabolism in Merkel cell carcinoma
30 augusti 2019
Abstract och ramberättelse

10. Lotta Walz
Consequences of inadequate use of glucose lowering drugs and associated risk factors
14 juni 2019
Abstract och ramberättelse

9. Carl Söderberg
11 juni 2019
Evaluation of postmortem toxicological results
Abstract och ramberättelse

8. Rong Yu
Molecular mechanisms of human mitochondrial dynamics: Inspiration and Challenge 
5 juni 2019
Abstract och ramberättelse

7. Johan Karlsson Törlén
From risk indices to reconstitution of immunity: Studies of outcome-related factors in patients undergoing allogeneic hematopoietic stem cell transplantation 
24 maj 2019
Abstract och ramberättelse

6. Ellin Kristina Hillert
Mechanistic studies of a novel inhibitor of the ubiquitin-proteasome system
24 maj 2019
Abstract och ramberättelse

5. Anna Kristiansen
Genetic and morphological studies of tumor heterogeneity, multifocality and outcome in locally advanced prostate cancer
3 maj 2019
Abstract och ramberättelse

4. Aravindh Subramani
Feeling the force: Role of AmotL2 in normal development and cancer
12 april 2019
Abstract och ramberättelse

3. Kristina Witt
Cripto-1: potential target for cancer immunotherapy?!
15 mars 2019
Abstract och ramberättelse

2. Anna Kullberg
Person-centered shift handovers in oncological inpatient care
22 februari 2019
Abstract och ramberättelse

1. Arian Lundberg
Transcriptional gene signatures: passing the restriction point for routine clinical implementation
25 januari 2019
Abstract och ramberättelse

2003-2018

Documents

Erika Rindsjö
2024-04-19