Reglering av immunsvaret i tumörer – Charlotte Rolnys forskargrupp

Publikationer

Utvalda publikationer

• Article: GYNECOLOGIC ONCOLOGY. 2020;159(3):860-868

  High density of stroma-localized CD11c-positive macrophages is associated with longer overall survival in high-grade serous ovarian cancer.

  Corvigno S; Mezheyeuski A; De La Fuente LM; Westbom-Fremer S; Carlson JW; Fernebro J; Åvall-Lundqvist E; Kannisto P; Hedenfalk I; Malander S; Rolny C; Dahlstrand H; Östman A
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(44):27556-27565

  MNK2 governs the macrophage antiinflammatory phenotype.

  Bartish M; Tong D; Pan Y; Wallerius M; Liu H; Ristau J; de Souza Ferreira S; Wallmann T; van Hoef V; Masvidal L; Kerzel T; Joly A-L; Goncalves C; Preston SEJ; Ebrahimian T; Seitz C; Bergh J; Pietras K; Lehoux S; Naldini L; Andersson J; Squadrito ML; Del Rincón SV; Larsson O; Rolny C
• Article: CANCERS. 2019;11(10):1479

  STAT3 Activity Promotes Programmed-Death Ligand 1 Expression and Suppresses Immune Responses in Breast Cancer.

  Zerdes I; Wallerius M; Sifakis EG; Wallmann T; Betts S; Bartish M; Tsesmetzis N; Tobin NP; Coucoravas C; Bergh J; Rassidakis GZ; Rolny C; Foukakis T
• Article: ISCIENCE. 2018;9:71-83

  Microglia Induce PDGFRB Expression in Glioma Cells to Enhance Their Migratory Capacity.

  Wallmann T; Zhang X-M; Wallerius M; Bolin S; Joly A-L; Sobocki C; Leiss L; Jiang Y; Bergh J; Holland EC; Enger PØ; Andersson J; Swartling FJ; Miletic H; Uhrbom L; Harris RA; Rolny C
• Article: CANCER RESEARCH. 2016;76(11):3166-3178

  Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages.

  Wallerius M; Wallmann T; Bartish M; Östling J; Mezheyeuski A; Tobin NP; Nygren E; Pangigadde P; Pellegrini P; Squadrito ML; Pontén F; Hartman J; Bergh J; De Milito A; De Palma M; Östman A; Andersson J; Rolny C
• Article: CELL REPORTS. 2016;15(9):2000-2011

  Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis.

  Georgoudaki A-M; Prokopec KE; Boura VF; Hellqvist E; Sohn S; Östling J; Dahan R; Harris RA; Rantalainen M; Klevebring D; Sund M; Brage SE; Fuxe J; Rolny C; Li F; Ravetch JV; Karlsson MCI
• Article: SCIENCE. 2015;347(6226):1138-1142

  Brain structure. Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq.

  Zeisel A; Muñoz-Manchado AB; Codeluppi S; Lönnerberg P; La Manno G; Juréus A; Marques S; Munguba H; He L; Betsholtz C; Rolny C; Castelo-Branco G; Hjerling-Leffler J; Linnarsson S
• Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2011;31(4):741-749

  Systemic and targeted delivery of semaphorin 3A inhibits tumor angiogenesis and progression in mouse tumor models.

  Casazza A; Fu X; Johansson I; Capparuccia L; Andersson F; Giustacchini A; Squadrito ML; Venneri MA; Mazzone M; Larsson E; Carmeliet P; De Palma M; Naldini L; Tamagnone L; Rolny C
• Article: CANCER CELL. 2011;19(1):31-44

  HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF.

  Rolny C; Mazzone M; Tugues S; Laoui D; Johansson I; Coulon C; Squadrito ML; Segura I; Li X; Knevels E; Costa S; Vinckier S; Dresselaer T; Åkerud P; De Mol M; Salomäki H; Phillipson M; Wyns S; Larsson E; Buysschaert I; Botling J; Himmelreich U; Van Ginderachter JA; De Palma M; Dewerchin M; Claesson-Welsh L; Carmeliet P

Medlemmar och kontakt

Gruppledare

• 

  Charlotte Rolny

  Senior Forskare | Docent

  E-postadress charlotte.rolny@ki.se

Alla medlemmar i gruppen

• 

  Kaveri Banerjee

  Postdoktorala Studier

  E-postadress kaveri.banerjee@ki.se
• Alessia Gennai

  Anknuten till Forskning

  E-postadress alessia.gennai@ki.se
• Peili Jiao

  Anknuten till Forskning

  E-postadress peili.jiao@ki.se
• Ophélie Le Chapelain

  Postdoktorala Studier

  E-postadress ophelie.le.chapelain@ki.se
• 

  Charlotte Rolny

  Senior Forskare | Docent

  E-postadress charlotte.rolny@ki.se