Föreläsningar och seminarier

MEB seminarium: Professor Brian M. D'Onofrio

2015-11-1016:00 to 17:00 Föreläsningsalen Petrén, Nobels väg 12B, Solna Campus Campus Solna

Titel: ADHD Medication and Substance Use Problems: Pharmaco-epidemiology studies in Sweden and the US

Arrangeras av: Doktorandprogrammet i Epidemiologi och SINGS Research School


Attention Deficit/Hyperactivity Disorder (ADHD) is a common and relatively stable developmental disorder that is associated with significant disability. Drug treatment of ADHD is now widely used in the United States and in Europe. Randomized controlled trials (RCTs) suggest that ADHD medication has beneficial short-term effects on symptoms of ADHD and some co-occurring disorders. RCTs of ADHD medication have serious limitations, however, including the inability to generalize to individuals with serious comorbid problems, study rare and serious outcomes, and adequately examine long-term outcomes. Thus, the increasing use of ADHD medications is being heavily debated because of the uncertainty regarding both short-term and long-term effects, particularly concerns about misuse and overuse. In this seminar I will discuss how our research teams is trying to more precisely identify the specific risks and benefits of ADHD medication for substance use problems, particularly with samples and designs that can explore rare outcomes with long follow-up time and treatments periods. I will present findings from analyses of datasets from Sweden (using national registers) and the United States (using health insurance claims) that used within-individual comparisons and advanced statistical techniques to account for stable and time-varying confounding.

Contact person: Ralf Kuja-Halkola
EpidemiologiPsykisk ohälsa