Publications 1995-2007 (selected)
Integrative Physiology research group
Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle.
Diabetes. Jun;56(6):1630-7. Epub 2007 Mar 15. (2007)
siRNA Based Gene Silencing Reveals Specialized Roles of IRS-1/Akt2 and IRS-2/Akt1 in Glucose and Lipid Metabolism in Human Skeletal Muscle.
Cell Metab. Jul;4(1):89-96. (2006)
Insulin signaling and glucose transport in skeletal muscle from first-degree relatives of type 2 diabetic patients.
Diabetes. May;55(5):1283-8 (2006)
Changes in Exercise-Induced Gene Expression in 5'-AMP-Activated Changes in exercise-induced gene expression in 5'-AMP-activated protein kinase gamma3-null and gamma3 R225Q transgenic mice.
Diabetes. Dec;54(12):3484-9. (2005)
Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects.
Diabetes. Jun;54(6):1692-7. (2005)
MEF2 activation in differentiated primary human skeletal muscle cultures requires coordinated involvement of parallel pathways.
Am J Physiol Cell Physiol. Jun;286(6):C1410-6. (2004)
Exercise-induced changes in expression and activity of proteins involved in insulin-signal-transduction in skeletal muscle: Differential effects on IRS-1 and IRS-2.
Proc Natl Acad Sci USA 97: 38-43, (2000)
Characterization of signal transduction and glucose transport in skeletal muscle from Type 2 (non-insulin-dependent) diabetic patients.
Diabetes 49: 284-292, (2000)
Discovery of a small molecule insulin mimetic with antidiabetic activity in mice.
Science. May 7;284(5416):974-7. (1999)
Divergent effects of excercise on metabolic and mitogenic signaling pathways in human skeletal muscle.
Faseb journal, 12,1379-1389, (1998)
Excercise-induced overexpression of key regulatory proteins involved in glucose uptake and metabolism in tetraplegig persons: Molecular mechanisms for improved glucose homeostasis.
FASEB journal 12, 1702-1712, (1998)
In vitro studies of human skeletal muscle. Hormonal and metabolic regulation of glucose transport.
Acta Physiol Scand 155: 1-96, (1995)