STINT Network
The STINT network is funded by STINT Institutional Grants for Younger Researchers. Collaboration takes place between the Schulte lab, and the laboratories of Dr. Vitezslav Bryja, Masaryk University, Brno, Czech Republic and Dr. Alexandra Schambony, University of Erlangen, Germany. The focus is WNT/Frizzled signaling and the role of intracellular scaffolding for signal transduction.
STINT network meeting in Stockholm, April 16-17, 2009
The three research teams of the network will meet in Stockholm in order to discuss current and future projects and personnel exchange.
Venue: The Dept Physiology & Pharmacology at KI Solna
Invited external speaker: Prof Tommy Andersson, Lund University, Sweden (the lecture will be announced and is open to the public - limited space!)
- STINT
- Bryja laboratory at Masaryk University, Czech Republic
- Schambony laboratory at University of Erlangen, Germany
STINT at KI's Grants Office - February 2009
STINT invited Gunnar Schulte to an information meeting at Karolinska Institutet to present his ideas and experiences as a recipient of the STINT Institutional Grant for Younger Researchers. Gunnar Schulte's presentation is available as a PDF (link below).
European WNT2010 meeting as STINT network meeting
The WNT2010 meeting held the 27th - 30th of October 2010 at Karolinska Institutet serves as a STINT network meeting. It offers the network a perfect forum to communicate recent findings and exchange knowledge and experiences. All members of the Bryja, Schambony and Schulte laboratories participate actively in the meeting.
In addition to support from STINT, the meeting was financed with money from the the Scandinavian Physiological Society, Swedish Research Coucnil, the Wenner-Gren Foundations, EMBO Young Investigators, the Company of Biologists, Sektionen f läkemedelslära and Merck Serono
The guest editors Gunnar Schulte, Vitezslav Bryja and Alexandra Schambony have invited the participants of the WNT2010 meeting to submit original articles and reviews to Acta Physiologica to publish a special issue on the topic WNT signaling in Physiology & Disease. The special issue is planned to appear during summer 2011.
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Publication originating from the STINT network
Collaboration between the three labs has led to a series of scientific articles with all three or two of the network partners as co-authors.
review articles
beta-arrestins - scaffolds and signaling elements essential for WNT/Frizzled signaling pathways?
Brit J Pharmacol. 2010 159(5):1051-8
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original research articles
Beta-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways.
EMBO Rep. 2008;9(12):1244-50.
Mitogen-activated protein kinases promote WNT/{beta}-catenin signaling via phosphorylation of LRP6.
Mol Cell Biol. 2011. 31(1):179-89.
WNT-5A stimulates the GDP/GTP exchange at pertussis toxin-sensitive heterotrimeric G proteins
Cell Signal. 2011. 23(3):550-4.
Sequential activation and inactivation of dishevelled in the Wnt/beta-catenin pathway by casein kinases
J. Biol. Chem. published February 1, 2011 as doi:10.1074/jbc.M110.169870
Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P(2) to LRP6 phosphorylation.
EMBO J.
Personnel exchange
2008
Michaela Kilander Stockholm - Brno (3 months, 2008)
2009
Ranjani Sri Ganji Brno - Stockholm (2 months, 2009)
Igor Cervenka Brno - Stockholm (3 months, 2009)
Ann-Caroline Feike Erlangen - Stockholm (2 months, 2009)
Ondrej Bernatik Brno - Erlangen (2 months, 2009)
2010
Vitezslav Kriz Brno - Stockholm (3 months, 2010)
Vitezslav Kriz Brno - Erlangen (2 months, 2010)
Katharina Kirchner Erlangen - Stockholm (2 weeks, 2010)
Jan Masek Brno - Stockholm (2 months, 2010)
2011
Marketa Kaucka Brno - Stockholm (2 months, planned 2011)
Carina Sandbäck Stockholm - Brno (1 months, planned 2011)
Javier Becerril Brno-Stockholm (6 months, planned 2011)
