Publications 1995-2007 (selected)

Glund S, Deshmukh A, Long YC, Moller T, Koistinen HA, Caidahl K, Zierath JR, Krook A.

Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle.

Diabetes. Jun;56(6):1630-7. Epub 2007 Mar 15. (2007)

• Link to the abstract in PubMed

Bouzakri K, Zachrisson A, Al-Khalili L, Zhang BB, Koistinen HA, Krook A, Zierath JR.

siRNA Based Gene Silencing Reveals Specialized Roles of IRS-1/Akt2 and IRS-2/Akt1 in Glucose and Lipid Metabolism in Human Skeletal Muscle.

Cell Metab. Jul;4(1):89-96. (2006)

• Link to the abstract in PubMed

Karlsson HK, Ahlsen M, Zierath JR, Wallberg-Henriksson H, Koistinen HA.

Insulin signaling and glucose transport in skeletal muscle from first-degree relatives of type 2 diabetic patients.

Diabetes. May;55(5):1283-8 (2006)

• Link to the abstract in PubMed

Barnes BR, Long YC, Steiler TL, Leng Y, Galuska D, Wojtaszewski JF, Andersson L, Zierath JR.

Changes in Exercise-Induced Gene Expression in 5'-AMP-Activated Changes in exercise-induced gene expression in 5'-AMP-activated protein kinase gamma3-null and gamma3 R225Q transgenic mice.

Diabetes. Dec;54(12):3484-9. (2005)

• Link to the abstract in PubMed

Karlsson HK, Zierath JR, Kane S, Krook A, Lienhard GE, Wallberg-Henriksson H.

Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects.

Diabetes. Jun;54(6):1692-7. (2005)

• Link to the abstract in PubMed

Al-Khalili L, Chibalin AV, Yu M, Sjodin B, Nylen C, Zierath JR, Krook A.

MEF2 activation in differentiated primary human skeletal muscle cultures requires coordinated involvement of parallel pathways.

Am J Physiol Cell Physiol. Jun;286(6):C1410-6. (2004)

• Link to the abstract in PubMed

Chibalin AV, Yu M, Ryder JW, Song XM, Galuska D, Krook A, Wallberg-Henriksson H and Zierath JR.

Exercise-induced changes in expression and activity of proteins involved in insulin-signal-transduction in skeletal muscle: Differential effects on IRS-1 and IRS-2.

Proc Natl Acad Sci USA 97: 38-43, (2000)

• Link to the abstract in PubMed

Krook A, Björnholm M, Jiang X-J, Galuska D, Fahlman R, Myers M, Wallberg-Henriksson H and Zierath J.

Characterization of signal transduction and glucose transport in skeletal muscle from Type 2 (non-insulin-dependent) diabetic patients.

Diabetes 49: 284-292, (2000)

• Link to the abstract in PubMed

Zhang B, Salituro G, Szalkowski D, Li Z, Zhang Y, Royo I, Vilella D, Diez MT, Pelaez F, Ruby C, Kendall RL, Mao X, Griffin P, Calaycay J, Zierath JR, Heck JV, Smith RG, Moller DE.

Discovery of a small molecule insulin mimetic with antidiabetic activity in mice.

Science. May 7;284(5416):974-7. (1999)

• Link to the abstract in PubMed

Widegren U, Jiang XJ, Krook A, Chibalin AV, Björnholm M, Tally M, Roth RA, Henriksson J, Wallberg-Henriksson H, and Zierath JR.

Divergent effects of excercise on metabolic and mitogenic signaling pathways in human skeletal muscle.

Faseb journal, 12,1379-1389, (1998)

• Link to the abstract in PubMed

Hjeltnes N, Galuska D, Björnholm M, Asknes A-K, Lannem A, Zierath JR, and Wallberg-Henriksson H.

Excercise-induced overexpression of key regulatory proteins involved in glucose uptake and metabolism in tetraplegig persons: Molecular mechanisms for improved glucose homeostasis.

FASEB journal 12, 1702-1712, (1998)

Zierath JR.

In vitro studies of human skeletal muscle. Hormonal and metabolic regulation of glucose transport.

Acta Physiol Scand 155: 1-96, (1995)

• Link to the abstract in PubMed