Cell biology
This area is focusing on basic mechanisms in causation of tumors and tumor progression, including host responses to tumor development.
It includes genetic factors and their protein products, such as oncogenes, cell cycle regulating genes, signal transduction genes, growth factors, apoptosis and cell ageing controls, and suppressor genes and susceptibility genes.
Genetic cancer susceptibilities
This area also includes studies on genetic cancer susceptibility and familiar cancers, related molecular epidemiology, on the interplay between malignant and normal cells, cell adhesion, angiogenesis, metastasis formation, aspects on tumor regression, and research on the relationship between infections and tumor development, as well as related bioinformatics and biocomplexity.
The application of this knowledge in the development on experimental treatments, such as gene and immunotherapy, and preventive measures is also included in this area of research.
Research groups in cell biology
- Elias Arnér, biochemistry
- Marie Arsenian Henriksson, MYC genes
- Magnus Björkholm, haematology
- Bertha Brodin, oncology-pathology
- Karin Dahlman-Wright, estrogen signaling
- Nico Dantuma, ubiquitin/proteasome system
- Tomas Ekström, medical epigenetics
- Lennart Eriksson, liver cancer
- Ingemar Ernberg, tumor biology
- Bengt Fadeel, apoptosis
- Leonard Girnita, beta-arrestins in cancer
- Dan Grandér, molecular mechanisms of action of the anti-cancer drugs
- Eva Hellström Lindberg, myelodysplastic syndromes
- Lars Holmgren, experimental cancer research
- Lifu Hu, development of cancer
- Bertrand Joseph, apoptosis
- Eva Klein, cancer immunology
- Georg Klein, cancer immunology
- Per Kogner, childhood neural tumours
- Catharina Larsson, medical genetics
- Olle Larsson, insulin-like growth factor 1 receptor (IGF-1R)
- Janne Lehtiö, proteomics
- Stig Linder, drug development
- Kristina Lindsten, deubiquitylating enzymes (DUBs)
- Andreas Lundqvist, cell-based immune therapy for cancer
- Håkan Mellstedt, oncological biotherapy
- Monica Nistér, cellular and molecular tumour pathology
- Christer Paul, acute myeloid leukemia
- Kristian Pietras, vascular biology
- Birgitta Sander, malignant lymphoma
- Galina Selivanova, p53
- Camilla Sjögren, structural maintenance of chromosome (SMC)
- Maria Shoshan, energy metabolism of tumor cells
- Staffan Strömblad, role of integrins
- Rune Toftgård, drug development
- Annika Wallberg, regulation of gene transcription
- Boris Zhivotovsky, apoptosis
- Elisabeth Åvall, oncology-pathology


