Professor of Clinical Metabolic Research at the Department of Medicine, Huddinge since 1992.
Bo Angelin and his co-workers are studying the body's metabolisation chiefly of the blood fat, cholesterol and looking for new ways to affect the body's cholesterol content. The research group have been studying familial hypercholesterolaemia (where cells are unable to assimilate the cholesterol) for many years from a range of different perspectives. The starting point has been the work of the clinic in which patients with disease are investigated, treated and monitored. The patient contacts provide the opportunity to identify families with a predisposition to disease.
The research group has also discovered that in around one fifth of patients, the known disease genes have not mutated. Accordingly, there is probably at least one more gene in which the mutation can be. Using molecular genetic methods, the researchers are now looking for new disease genes.