Selected publications

Meeths M, Chiang SC, Wood SM, Entesarian M, Schlums H, Bang B, Nordenskjöld E, Björklund C, Jakovljevic G, Jazbec J, Hasle H, Holmqvist BM, Rajic L, Pfeifer S, Rosthøj S, Sabel M, Salmi TT, Stokland T, Winiarski J, Ljunggren HG, Fadeel B, Nordenskjöld M, Henter JI, Bryceson YT.

Familial hemophagocytic lymphohistiocytosis type 3 (FHL3) caused by deep intronic mutation and inversion in UNC13D.

Blood. 2011 Sep 19.

• Abstract

Jessen B, Maul-Pavicic A, Ufheil H, Vraetz T, Enders A, Lehmberg K, Längler A, Gross-Wieltsch U, Bay A, Kaya Z, Bryceson YT, Koscielniak E, Badawy S, Davies G, Hufnagel M, Schmitt-Gräff A, Aichele P, Zur Stadt U, Schwarz K, Ehl S.

Subtle differences in CTL cytotoxicity determine susceptibility to hemophagocytic lymphohistiocytosis in mice and humans with Chediak-Higashi syndrome.

Blood. 2011 Aug 30.

• Abstract

Hagberg N, Berggren O, Leonard D, Weber G, Bryceson YT, Alm GV, Eloranta ML, Rönnblom L.

IFN-± production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes is promoted by NK cells via MIP-1² and LFA-1.

J Immunol, 186:5085-5094, 2011.

• Abstract

Macartney CA, Weitzman S, Wood SM, Bansal D, Steele M, Meeths M, Abdelhaleem M, Bryceson YT.

Unusual functional manifestations of a novel STX11 frameshift mutation in two infants with familial hemophagocytic lymphohistiocytosis type 4 (FHL4).

Pediatr Blood Cancer. 56: 654-657. 2011.

• Abstract

Theorell J, Schlums H, Chiang SC, Huang TY, Tattermusch A, Wood SM, Bryceson YT.

Sensitive and viable quantification of inside-out signals for LFA-1 activation in human cytotoxic lymphocytes by flow cytometry.

J Immunol Methods, 366: 106-118, 2011.

• Abstract

Maul-Pavicic A, Chiang SC, Rensing-Ehl A, Jessen B, Fauriat C, Wood SM, Sjöqvist S, Hufnagel M, Schulze I, Bass T, Schamel WW, Fuchs S, Pircher H, McCarl CA, Mikoshiba K, Schwarz K, Feske S, Bryceson YT, Ehl S.

ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis

Proc Natl Acad Sci USA, 108: 3324-3329, 2011.

• Abstract

Henter JI, Palmkvist-Kaijser K, Holzgraefe B, Bryceson YT, Palmér K.

Cytotoxic therapy for severe swine flu A/H1N1.

Lancet. 2010 Dec 18;376(9758):2116. No abstract available.

Machaczka M, Vaktnäs J, Chiang SC, Bryceson YT.

Alemtuzumab treatment for hemophagocytic lymphohistiocytosis.

Nat Rev Clin Oncol. 2010 Oct;7(10). doi: 10.1038/nrclinonc.2010.40-c1. No abstract available.

Bryceson YT, Fauriat C, Nunes JM, Wood SM, Björkström NK, Long EO, Ljunggren HG.

Functional analysis of human NK cells by flow cytometry.

Methods Mol Biol. 2010;612:335-52.

• Abstract

Meeths M, Entesarian M, Al-Herz W, Chiang SC, Wood SM, Al-Ateeqi W, Almazan F, Boelens JJ, Hasle H, Ifversen M, Lund B, van den Berg JM, Gustafsson B, Hjelmqvist H, Nordenskjöld M, Bryceson YT, Henter JI.

Spectrum of clinical presentations in familial hemophagocytic lymphohistiocytosis type 5 patients with mutations in STXBP2

Blood, 116: 2635-2643, 2010.

• Abstract

Kim HS, Das A, Gross CC, Bryceson YT, Long EO.

Synergistic signals for natural cytotoxicity are required to overcome inhibition by c-Cbl ubiquitin ligase

Immunity, 32: 175-186, 2010.

• Abstract

Fauriat C, Long EO, Ljunggren HG, Bryceson YT.

Regulation of human NK-cell cytokine and chemokine production by target cell recognition

Blood, 115: 2167-2176, 2010.

• Abstract

Wood SM, Meeths M, Chiang SC, Bechensteen AG, Boelens JJ, Heilmann C, Horiuchi H, Rosthøj S, Rutynowska O, Winiarski J, Stow JL, Nordenskjöld M, Henter JI, Ljunggren HG, Bryceson YT.

Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity

Blood, 114: 4117-4127, 2009.

• Abstract

Bryceson YT, Ljunggren HG, Long EO.

Minimal requirement for induction of natural cytotoxicity and intersection of activation signals by inhibitory receptors.

Blood, 114: 2657-2666, 2009.

• Abstract

Liu D, Bryceson YT, Meckel T, Vasiliver-Shamis G, Dustin ML, Long EO.

Integrin-dependent organization and bidirectional vesicular traffic at cytotoxic immune synapses

Immunity, 31: 99-109, 2009.

• Abstract

Bryceson YT, Rudd E, Zheng C, Edner J, Ma D, Wood SM, Bechensteen AG, Boelens JJ, Celkan T, Farah RA, Hultenby K, Winiarski J, Roche PA, Nordenskjöld M, Henter JI, Long EO, Ljunggren HG.

Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients.

Blood, 110: 1906-15, 2007.

• Abstract

Bryceson YT, March ME, Ljunggren HG, Long EO.

Minimal requirement for induction of natural cytotoxicity and intersection of activation signals by inhibitory receptors

Blood, 107: 159-166, 2006.

• Abstract

Bryceson YT, March ME, Barber DF, Ljunggren HG, Long EO.

Cytolytic granule polarization and degranulation controlled by different receptors in resting NK cells

J Exp Med, 202: 1001-1012, 2005.

• Abstract