Familial hemophagocytic lymphohistiocytosis type 3 (FHL3) caused by deep intronic mutation and inversion in UNC13D.
Blood. 2011 Sep 19.
Subtle differences in CTL cytotoxicity determine susceptibility to hemophagocytic lymphohistiocytosis in mice and humans with Chediak-Higashi syndrome.
Blood. 2011 Aug 30.
IFN-± production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes is promoted by NK cells via MIP-1² and LFA-1.
J Immunol, 186:5085-5094, 2011.
Unusual functional manifestations of a novel STX11 frameshift mutation in two infants with familial hemophagocytic lymphohistiocytosis type 4 (FHL4).
Pediatr Blood Cancer. 56: 654-657. 2011.
Sensitive and viable quantification of inside-out signals for LFA-1 activation in human cytotoxic lymphocytes by flow cytometry.
J Immunol Methods, 366: 106-118, 2011.
ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis
Proc Natl Acad Sci USA, 108: 3324-3329, 2011.
Cytotoxic therapy for severe swine flu A/H1N1.
Lancet. 2010 Dec 18;376(9758):2116. No abstract available.
Alemtuzumab treatment for hemophagocytic lymphohistiocytosis.
Nat Rev Clin Oncol. 2010 Oct;7(10). doi: 10.1038/nrclinonc.2010.40-c1. No abstract available.
Functional analysis of human NK cells by flow cytometry.
Methods Mol Biol. 2010;612:335-52.
Spectrum of clinical presentations in familial hemophagocytic lymphohistiocytosis type 5 patients with mutations in STXBP2
Blood, 116: 2635-2643, 2010.
Synergistic signals for natural cytotoxicity are required to overcome inhibition by c-Cbl ubiquitin ligase
Immunity, 32: 175-186, 2010.
Regulation of human NK-cell cytokine and chemokine production by target cell recognition
Blood, 115: 2167-2176, 2010.
Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity
Blood, 114: 4117-4127, 2009.
Minimal requirement for induction of natural cytotoxicity and intersection of activation signals by inhibitory receptors.
Blood, 114: 2657-2666, 2009.
Integrin-dependent organization and bidirectional vesicular traffic at cytotoxic immune synapses
Immunity, 31: 99-109, 2009.
Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients.
Blood, 110: 1906-15, 2007.
Minimal requirement for induction of natural cytotoxicity and intersection of activation signals by inhibitory receptors
Blood, 107: 159-166, 2006.
Cytolytic granule polarization and degranulation controlled by different receptors in resting NK cells
J Exp Med, 202: 1001-1012, 2005.