Astrid Fagraeus Laboratory
The Astrid Fagraeus Laboratory (AFL) is one of the world's most modern laboratories for infection experiments on animals. With effect from 1 January 2012, the laboratory is part of Comparative Medicine at Karolinska Institutet.
Among other things, we conduct studies on protection against communicable diseases at AFL. This applies, for example, to the development of new vaccines, new methods of treatment and fundamental studies of the body's own protective mechanisms. An important area is the development of a vaccine against HIV/AIDS. Experiments with monkeys are indispensable in this connection.
Research on diseases that affect human health, such as Alzheimer's, Parkinson's, depression and schizophrenia is also performed, as are studies on the effects and side-effects of new drugs under development.
The laboratory facility
The laboratory was first used in 2003. We have rooms for conducting experiments with animals infected with microorganisms up to risk class 3.
The building is constructed in a very flexible way and is divided into zones for different protection classes and types of animals. The apparatus and equipment are of the highest quality and include a biophotonic scanner for the measurement of luminescence and fluorescence in viruses, bacteria and cells, principally in mice.
Animal husbandry at the Astrid Fagraeus Laboratory
There is space for mice, rats, guinea pigs, rabbits, pigs and monkeys (macaques) at the laboratory.
All animals at the laboratory are kept in an environment that is suited to the animal's physiological and behavioural needs. The monkeys, for example, are given an opportunity to express their natural behaviour such as climbing, leaping around in the cage, searching for food, socialising and grooming one another.
Researchers, research institutes and private enterprises are welcome to make use of the facility at the Astrid Fagraeus Laboratory for their research. Please feel free to contact us for further information.