Niklas Zethraeus
PhD, Senior Researcher in Health Economics
Economic evaluation of health care programmes
I have carried out a large number of practical applications of economic evaluation. Examples are economic evaluations in the areas of gallstone disease, congestive heart failure, and osteoporosis. Modelling and handling uncertainty are important aspects of economic evaluation. First I have developed computer models of diseases and costs, for instance a model of osteoporosis that have been used in numerous cost-effectiveness studies. Furthermore I have worked extensively on developing methods for handling uncertainty in economic evaluations. The development of the so-called net benefit approach has facilitated the analysis, interpretation and presentation of uncertainty, when the economic evaluation is based on e.g. a clinical randomized trial, with individual cost and health effects data.
Selected Publications
Willingness to pay for hormone replacement therapy.
Health Econ 1998;7:31-8.
Definition, interpretation and calculation of cost-effectiveness acceptability curves.
Health Econ 2000;9:623-30.
Cost-effectiveness of the treatment and prevention of osteoporosis - a review of the literature and a reference model.
Osteoporos Int 2007;18:9-23.
The cost-effectiveness of the treatment of high risk women with osteoporosis, hypertension and hyperlipidaemia in Sweden.
Osteoporos Int 2008;19:819-27.
A randomized trial of the effect of estrogen and testosterone on economic behavior.
Proc. Natl. Acad. Sci. USA 2009;106:6535-8.
