Föreläsningar och seminarier

IMM Seminar - The Case-Cohort design: What it is and how it can be used in register-based research

2016-01-2814:00 till 15:00 Blå hallen, IMM, Nobels väg 13Campus Solna

Speaker:          

Anna Johansson, Statistician, MEB

Abstract:

I will give a brief theoretical background and history of case-cohort studies, which dates back to the key publication by Prentice in 1986. I will talk about in which situations the case-cohort design is useful, in particular in a register-based setting with total population registers. I will briefly describe what you can estimate from a case-cohort design and the different weighting schemes to be used in the analysis to account for the sampling. As an example, I will present my own study on risk for breast cancer following pregnancy using data from the Multi-Generation Register and the Swedish Cancer Register. In this study we utilised the case-cohort design to reduce the dataset and to improve computational efficiency. Some Stata code for how to do it will also be presented.

Host:

Josefin Edwall Löfvenborg, MSc Nutrition, PhD student, Unit of Epidemiology, IMM

Contact person: Josefin Edwall Löfvenborg