Neuropsykofarmakologi

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Vi forskar på biogeniska aminer i hjärnan: molekylär biologi, biokemi och fysiologi, med särskild betoning på läkemedelsutveckling inom neuropsykofarmakologi.

Mer information om forskningen i vår grupp finns på engelska

Gruppmedlemmar

Monica MarcusSenior lab manager
Torgny SvenssonProfessor, senior
Joep TitulaerFOU-praktikant, Student
 

Senaste publikationer

Role of concomitant inhibition of the norepinephrine transporter for the antipsychotic effect of quetiapine.
Björkholm C, Jardemark K, Marcus M, Malmerfelt A, Nyberg S, Schilström B, et al
Eur Neuropsychopharmacol 2013 Jul;23(7):709-20 

Celecoxib enhances the effect of reboxetine and fluoxetine on cortical noradrenaline and serotonin output in the rat.
Johansson D, Falk A, Marcus M, Svensson T
Prog. Neuropsychopharmacol. Biol. Psychiatry 2012 Oct;39(1):143-8 

Involvement of 5-HT2A receptor and α2-adrenoceptor blockade in the asenapine-induced elevation of prefrontal cortical monoamine outflow.
Frånberg O, Marcus M, Svensson T
Synapse 2012 Jul;66(7):650-60 

Augmentation by escitalopram, but not citalopram or R-citalopram, of the effects of low-dose risperidone: behavioral, biochemical, and electrophysiological evidence.
Marcus M, Jardemark K, Malmerfelt A, Gertow J, Konradsson-Geuken A, Svensson T
Synapse 2012 Apr;66(4):277-90 

Differential effects of AMPA receptor potentiators and glycine reuptake inhibitors on antipsychotic efficacy and prefrontal glutamatergic transmission.
Jardemark K, Marcus M, Malmerfelt A, Shahid M, Svensson T
Psychopharmacology (Berl.) 2012 May;221(1):115-31 

Smoking, quitting, and psychiatric disease: a review.
Aubin H, Rollema H, Svensson T, Winterer G
Neurosci Biobehav Rev 2012 Jan;36(1):271-84 

Effects of S-citalopram, citalopram, and R-citalopram on the firing patterns of dopamine neurons in the ventral tegmental area, N-methyl-D-aspartate receptor-mediated transmission in the medial prefrontal cortex and cognitive function in the rat.
Schilström B, Konradsson-Geuken A, Ivanov V, Gertow J, Feltmann K, Marcus M, et al
Synapse 2011 May;65(5):357-67 

Deuterium substitutions in the L-DOPA molecule improve its anti-akinetic potency without increasing dyskinesias.
Malmlöf T, Rylander D, Alken R, Schneider F, Svensson T, Cenci M, et al
Exp. Neurol. 2010 Oct;225(2):408-15 

Effects of asenapine on prefrontal N-methyl-D-aspartate receptor-mediated transmission: involvement of dopamine D1 receptors.
Jardemark K, Marcus M, Shahid M, Svensson T
Synapse 2010 Nov;64(11):870-4 

Reboxetine enhances the olanzapine-induced antipsychotic-like effect, cortical dopamine outflow and NMDA receptor-mediated transmission.
Marcus M, Jardemark K, Malmerfelt A, Björkholm C, Svensson T
Neuropsychopharmacology 2010 Aug;35(9):1952-61 

Kontakta forskargruppsledaren

Professor, senior

Torgny Svensson

Telefon: 08-524 879 21
Enhet: Svensson Torgny grupp - Neuropsykofarmakologi
E-post: Torgny.Svensson@ki.se

Neurofarmakologi