Toppublikationer

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Här listas aktuella publikationer i högt rankade vetenskapliga tidskrifter där forskare vid Karolinska Institutet medverkar.

161205
Human immune system variation
Brodin P, Davis MM
Nature Reviews Immunology (2016) Online 5 December. Review.

161205
Development and validation of risk prediction model for venous thromboembolism in postpartum women: multinational cohort study
Sultan AA, West J, Grainge MJ, Riley RD, Tata LJ, Stephansson O, Fleming KM, Nelson-Pierc C, Ludvigsson JF
BMJ (2016) Online 5 December. Research

161201
Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity
Li J, Casteels T, Frogne T et al.
Cell (2016) Online 1 December. Article.

161121
Sex-Discordant Blood Transfusions and Survival After Cardiac Surgery - A Nationwide Cohort Study
Holzmann MJSartipy U,  Olsson ML,  Dickman PEdgren G
Circulation (2016) Online 21 November. Correspondence.
På KI Nyheter: Inget samband mellan icke könsmatchade blodtransfusioner och risk för död

161118
Neural circuitry gets rewired
Adameyko I
Science (2016) Online 18 November. Perspective.

161117
Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study
Grundmann H, Glasner C, Albiger B et al.
The Lancet Infectious Diseases (2016) Online 17 November. Article.

161108
Effect of Tailored Dose-Dense Chemotherapy vs Standard 3-Weekly Adjuvant Chemotherapy on Recurrence-Free Survival AmongWomen With High-Risk Early Breast Cancer A Randomized Clinical Trial
Foukakis T, von Minckwitz G, Bengtsson N-O,  Brandberg Y, Wallberg B, Fornander T, Mlineritsch B, Schmatloch S, Singer CF, Steger G, Egle D, Karlsson E, Carlsson L, Loibl S, Untch M, Hellström M, Johansson H, Anderson H, Malmström P, Gnant M, Greil R, Möbus V, Bergh J
JAMA (2016) Online 8 November. Original Investigation.
På KI Nyheter: 
Skräddarsydd kemoterapi för tidig bröstcancer resulterar inte i signifikant förbättring

161107
Regulation of autoantibody activity by the IL-23–TH17 axis determines the onset of autoimmune disease
Pfeifle R, Rothe T, Ipseiz N et al.
Nature Immunology (2016) Online 7 November. Article.

161101
Health consequences of shift work and insufficient sleep
Kecklund G, Axelsson J
BMJ (2016) Online 1 November. Clinical Review.

161101
Association Between Prescription of Major Psychotropic Medications and Violent Reoffending After Prison Release
Chang Z, Lichtenstein P, Långström N, Larsson H, Fazel S
JAMA (2016) Online 1 November. Original Investigation.
På KI Nyheter: Psykiatrisk behandling mot upprepad våldsbrottslighet hos tidigare dömda

161031
Genome-wide analysis identifies 12 loci influencing human reproductive behavior
Barban N, Jansen R, de Vlaming R et al
Nature Genetics (2016) Online 31 October. Article.

161031
Lgr6 labels a rare population of mammary gland progenitor cells that are able to originate luminal mammary tumours
Blaas L, Pucci F, Messal HA, Andersson AB, Josue Ruiz EJ, Gerling M, Douagi I, Spencer-Dene B, Musch A, Mitter R, Bhaw L, Stone R, Bornhorst D, Sesay AK, Jonkers J, Stamp G, Malanchi I, Toftgård R, and Behrens A
Nature Cell Biology (2016) Online 31 October 2016. Article.
På KI Nyheter: Ursprungsceller för bröstcancer identifierade

161031
Neutrophils license iNKT cells to regulate self-reactive mouse B cell responses
Hägglöf T, Sedimbi SK, Yates JL, Parsa R, Hauff Salas B, Harris RA, Leadbetter EA,  Karlsson MCI
Nature Immunology (2016) Online 31 October. Article.
På KI Nyheter: Så hindras autoimmun sjukdom – mekanism upptäckt

161031
Single-cell sequencing of the small-RNA transcriptome
Faridani OR, Abdullayev I, Hagemann-Jensen M, Schell JP, Lanner F, Sandberg R
Nature Biotechnology (2016) Online 31 October. Brief Communications.
På KI Nyheter: Korta RNA-molekyler kartlagda i enskild cell

161027
Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages
Kee N, Volakakis N, Kirkeby A, Dahl L, Storvall H, Nolbrant S, Lahti L, Björklund ÅK, Gillberg L, Joodmardi E, Sandberg R, Parmar M, Perlmann T
Cell Stem Cell (2016). Online 27 October. Article.
På KI Nyheter: Gemensam forskning leder till ny Parkinsonbehandling

161027
Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson’s Disease
Kirkeby A,  Nolbrant S, Tiklova K,  Heuer A, Kee N, Cardoso T, Rylander Ottosson D,  Lelos MJ, Rifes P,  Dunnett SB, Grealish S,  Perlmann T, Parmar M
Cell Stem Cell (2016) Online 27 October. Clinical Progress.

161027
Mammalian Mitochondria and Aging: An Update
Kauppila TES, Kauppila JHK, Larsson N-G
Cell Metabolism (2016). Online 27 October. Review.

161026
The immunometabolite S-2-hydroxyglutarate regulates fate in CD8+ T-lymphocytes
Petros A. Tyrakis PA, Palazon A, Macias D, Lee KL, Phan AT, Veliça P, You J, Chia GS, Sim J, ADoedens A, Abelanet A, Evans CE, Griffiths JR, Poellinger L, Goldrath AW,  Johnson RS
Nature (2016) Online 26 October. Article.
På KI Nyheter: Självförnyande mördarceller nyckeln till att få immunterapi att fungera

161026
Translating genome-wide association findings into new therapeutics for psychiatry
Breen G, Li Q, Roth BL et al.
Nature Neuroscience (2016) Online 26 October. Commentary.

161024
Long-term exposure to ambient air pollution and traffic noise and incident hypertension in seven cohorts of the European study of cohorts for air pollution effects (ESCAPE)
Fuks KB, Weinmyar G, Basagaña X et al.
European Heart Journal (2016) Online 24 October. Meta-Analysis.

161020
Outcomes of Pregnancies for Women Undergoing Endoscopy While They Were Pregnant – a Nationwide Cohort Study 
Ludvigsson JFLebwohl BEkbom A, Kiran R, Green PHR , Höijer JStephansson O
Gastroenterology (2016) Online 20 October. Accepted manuscript.
På KI Nyheter: Nya rön om endoskopi under graviditeten

161010
Common variants at PVT1, ATG13–AMBRA1, AHI1 and CLEC16A are associated with selective IgA deficiency
Bronson PG, ChangD, Bhangale T, Seldin MS, Ortmann W, Ferreira RC, Urcelay E, Fernández Pereira L, JMartin J, Plebani A, Lougaris V, Friman V, Freiberger T, Litzman J, Thon V, Pan-Hammarström Q, Hammarström L, Graham RG, Behrens TW
Nature Genetics (2016) Online 10 October. Letter.

161010
Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota
Wang J, Thingholm, LB, Skieceviciene J et al.
Nature Genetics (2016) Online 10 October. Article.

161006
Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells
La Manno G, Gyllborg D, Codeluppi S, Nishimura K, Salto C, Zeisel A, Borm LE, Stott SRW, Toledo EM, Villaescusa JC, Lönnerberg P, Ryge J, Barker RA, Arenas E, Linnarsson S
Cell (2016) Online 6 October. Resource.

161006
Daratumumab, Lenalidomide, and Dexamethasone for Multiple Myeloma 
Dimopoulos MA, Oriol A, Nahi H et al.
NEJM (2016) Online 6 October. Original Article. 

161003
Novel genetic loci underlying human intracranial volume identified through genome-wide association
Adams HHH, Hibar DP, Chouraki V et al.
Nature Neuroscience (2016) Online 3 October. Article

161003
Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia
Genovese G, Fromer M, Stahl EA, Ruderfer DM, Chambert K, Landén M, Moran JL, Purcell SM, Sklar P, Sullivan PF, Hultman CM, McCarroll SA
Nature Neuroscience (2016) Online 3 October. Article.

161003
Ultra-rare disruptive and damaging mutations influence educational attainment in the general population
Ganna A, Genovese G, Howrigan DP et al.
Nature Neuroscience (2016) Online 3 October. Brief Communication.

161003
Pooled Analysis of CNS Response to Alectinib in Two Studies of Pretreated Patients With ALK-Positive Non–Small-Cell Lung Cancer
Gadgeel SM, Shaw AT, Govindan R et al.
JCO (2016) Online 3 October. Original Reports.

161003
Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors
Luis TC, Luc S, Mizukami T, Boukarabila H, Thongjuea S, Woll PS, Azzoni E, Giustacchini A, Lutteropp M, Bouriez-Jones T, Vaidya H, Mead AJ, Atkinson D, Böiers C, Carrelha J, Macaulay IC, Patient R, Geissmann F, Nerlov C, Sandberg R, de Bruijn M, Blackburn CC, Godin I, Jacobsen SEW
Nature Immunology (2016) Online 3 October. Article.

160926
Analysis of allelic expression patterns in clonal somatic cells by single-cell RNA-seq
Reinius B, Mold JE, Ramsköld D, Deng Q, Johnsson P, Michaëlsson J, Frisén J and Sandberg R
Nature Genetics (2016) Online 26 September. Letter.
På KI News How our cells use mother’s and father’s genes

160926
Gene expression elucidates functional impact of polygenic risk for schizophrenia
Fromer M, Roussos P, Sieberts SK et al.
Nature Neuroscience (2016) online 26 September. Article.

160926
TSHZ3 deletion causes an autism syndrome and defects in cortical projection neurons
Caubit X, Gubellini P, Andrieux J et al.
Nature Genetics (2016) online 26 september. Article.

160926
Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps
Iotchkova V, Huang J, Morris JA et al  
Nature Genetics (2016) online 26 september

160922
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes
Segerstolpe Å, Palasantza A, Eliasson P, Andersson E, Andréasson A, Sun X, Picelli S, Sabirsh A, Clausen M, Bjursell MK, Smith DM, Kasper M, Ämmälä C, Sandberg R
Cell Metabolism (2016) Online 22 September. Resource.
På KI Nyheter Unik molekylär atlas över bukspottskörteln framtagen

160921
Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015
GBD 2015 SDG Collaborators
The Lancet (2016) Online 21 September. Article.

160920
Risk for Congenital Malformation With H1N1 Influenza Vaccine: A Cohort Study With Sibling Analysis
Ludvigsson JF, Ström P, Lundholm C, Cnattingius S, Ekbom A, Örtqvist Å, Feltelius N, Granath F, Stephansson O
Annals of Internal Medicine (2016) Online 20 September 2016. Original research.
På KI Nyheter: Svininfluensavaccin skadade inte barn i magen

160916
Beyond too little, too late and too much, too soon: a pathway towards evidence-based, respectful maternity care worldwide
Miller S, Abalos E, Chamillard M, Ciapponi A, Colaci D, Comandé D, Diaz V, Geller S,  Hanson C,  Langer A, Manuelli V, Millar K, Morhason-Bello I, Pileggi Castro C, Nogueira Pileggi V, Robinson N, Skaer M,  Souza JP, Vogel JP, Althabe F
The Lancet (2016) Online 16 September. Series.

160916
Drivers of maternity care in high-income countries: can health systems support woman-centred care?
Shaw D, Guise J-M, Shah N, Gemzell-Danielsson K, Joseph KS, Levy B, Wong F, Woodd S, Main EK
The Lancet (2016) Online 16 September. Series.

160912
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
Ehret GB, Ferreira T,  Chasman DI et al
Nature Genetics (2016) Online 12 September. Article.

160912
Sunscreen Use and Subsequent Melanoma Risk: A Population-Based Cohort Study
Reza Ghiasvand R, Weiderpass E, Green AC, Lund E,  Veierød MB
JCO (2016) Online 12 September. Original Report.

160912
Blood pressure regulation by CD4+ lymphocytes expressing choline acetyltransferase
Olofsson PS, Steinberg BE, Sobbi R, Cox MA, Ahmed MN, Oswald M, Szekeres F, Hanes WM, Introini A, Fang Liu S, Holodick NE, Rothstein TL, Lövdahl C, Chavan SS, Yang H, Pavlov VA, Broliden K, Andersson U, Diamond B, Miller EJ, Arner A, Gregersen PK, Backx PH, Mak TW, Tracey KJ
Nature Biotechnology (2016) Online 12 September. Letter.
På KI Nyheter: Immunceller kan reglera blodtrycket

160912
Glioma-induced caspase-3 inhibition in microglia promotes a tumor-supportive phenotype
Shen X, Burguillos MA, Osman AM, Frijhoff J, Carrillo-Jiménez A, Kanatani S, Augsten M, Saidi D, Rodhe J, Kavanagh E, Rongvaux A, Rraklli V, Nyman U, Holmberg J, Östman A, Flavell RA, Barragan A, Venero JL, Blomgren K, Joseph B
Nature Immunology (2016) Online 12 September. Article.
På KI Nyheter: Så kan vissa hjärntumörer använda immunförsvaret till sin fördel

160912
Novel glucose-sensing technology and hypoglycaemia in type 1 diabetes: a multicentre, non-masked, randomised controlled trial
Bolinder J, Antuna R, Geelhoed-Duijvestijn P, Kröger J, Weitgasser R
The Lancet (2016) Online 12 September. Article.
På KI Nyheter: Användning av ny teknik gav säkrare blodsockerkontroll vid diabetes

160905
Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation
Stellos K, Gatsiou A, Stamatelopoulos K, Perisic Matic L, John D, Francesca Lunella F, Jaé N, Rossbach O, Amrhein C, Sigala F, Boon RA, Fürtig B, Manavski Y, You X, Uchida S, Keller T, Boeckel J-N, Franco-Cereceda A, Maegdefessel L, Chen W, Schwalbe H, Bindereif A, Eriksson P, Hedin U, Zeiher AM, Dimmeler S
Nature Medicine (2016) Online 5 September. Article.

160831
Origin of the U87MG glioma cell line: Good news and bad news
Allen M, Bjerke M, Edlund H, Nelander S, Westermark B
Science Translational Medicine (2016) Online 31 August. Report.

160829
Visceral motor neuron diversity delineates a cellular basis for nipple- and pilo-erection muscle control
Furlan A, La Manno G, Lübke M, Häring M, Abdo H, Hochgerner H, Kupari J, Usoskin D, Airaksinen MS , Oliver G, Linnarsson S,  Ernfors P
Nature Neuroscience (2016) Online 29 August. Article.
På KI Nyheter: Särskilda nervceller för gåshud och bröstvårtans reaktion

160829
An AMPK-stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice
Rohm M, Schäfer M, Laurent V, Üstünel BE, Niopek K, Algire C, Hautzinger O, Sijmonsma TP, Zota A, Medrikova D, Pellegata NS, Ryden M, Kulyte A, Dahlman I, Arner P, Petrovic N, Cannon B, Amri E-Z, Kemp BE, Steinberg GR, Janovska P, Kopecky J, Wolfrum C, Blüher M, Berriel Diaz M, Herzig S
Nature Medicine (2016) Online 29 August. Article.

160826
Disentangling neural cell diversity using single-cell transcriptomics
Poulin J-F, Tasic B, Hjerling-Leffler J, Trimarchi JM, Awatramani R
Nature Neuroscience (2016) Online 26 August. Review. 

160824
Bariatric Surgery and Preterm Birth
Stephansson O, Johansson K, Näslund  I, Neovius M
NEJM (2016) Online 24 August. Letter to the Editor.
På KI Nyheter: Fetmakirurgi ökar risk för prematur födsel

160824
Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice
Vermeij WP, Dollé MET, Reiling E et al.
Nature (2016) Online 24 August. Letter.

160819
Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases
Franzén O, Ermel R, Cohain A, Akers NK, Di Narzo A, Talukdar HA, Foroughi-Asl HGiambartolomei C, Fullard JF, Sukhavasi K, Köks S, Gan L-M, Giannarelli C, Kovacic JC, Betsholtz CLosic B, Michoel T, Hao K,1 Roussos P, Skogsberg J, Ruusalepp A, Schadt EE, Björkegren JLM
Science (2016) Online 19 August. Report. 
På KI Nyheter: Risk-gener för sjukdomar som hjärtinfarkt och stroke identifierade

160818
Analysis of protein-coding genetic variation in 60,706 humans
Lek M, Karczewski KJ, Minikel EV et al
Nature (2018) Online 18 August. Article.
På KI Nyheter: Deep genetic catalog powers studies of disease and dna variation

160816
Pioglitazone use and risk of bladder cancer in patients with type 2 diabetes: retrospective cohort study using datasets from four European countries
Pasi Korhonen P, Heintjes EM, Williams R, Hoti F, Christopher S, Majak M, Kool-Houweling L, Strongman H, Linder M, Dolin P, Bahmanyar S.
BMJ (2016) Online 16 August. Research.

160811
Metabolic Control of Longevity
López-Otín C, Galluzzi L, Freije JMP, Madeo F, Kroemer G
Cell (2016) Online 11 August. Review.

160803
The chaperone co-inducer BGP-15 alleviates ventilation-induced diaphragm dysfunction
Salah H, Li M, Cacciani N, Gastaldello S, Ogilvie H, Akkad H, Namuduri AV, Morbidoni V, Artemenko KA, Balogh G, Martinez-Redondo V, Jannig P, Hedström Y, Dworkin BBergquist J, Ruas J, Vigh L, Salviati L, Larsson L
Science Translational Medicine (2016) Online 3 August. Research Article.

160801
C13orf31 (FAMIN) is a central regulator of immunometabolic function
Cader MZ, Boroviak K, Zhang Q, Assadi G, Kempster SL, Sewell GW, Saveljeva S, Ashcroft JW, Clare S, Mukhopadhyay S, Brown KP, Tschurtschenthaler M, Raine T, Doe B, Chilvers ER, Griffin JL, Kaneider NC, Floto RA, D’Amato M, Bradley A, Wakelam MJO, Dougan G, Kaser A
Nature Immunology (2016) Online 1 August. Article.

160801
A pleiotropic missense variant in SLC39A8 is associated with Crohn’s disease and human gut microbiome composition
Li D, Achkar J-P, Haritunians T et al
Gastroentereology (2016) Online 1 August. Article in press.

160727
Enantioselective Organocatalyzed Transformations of β-Ketoesters
Govender T, Arvidsson PI, Maguire GEM, Kruger HG, Naicker T.
Chemical Reviews (2016) Online 27 July. Review.

160725
Principles for RNA metabolism and alternative transcription initiation within closely spaced promoters
Chen Y, Pai A, Herudek J, Lubas M, Meola N, Järvelin AI, Andersson R, Pelechano V,  Steinmetz L, Heick Jensen T, Jensen H, Sandelin A
Nature Genetics (2016) Online 25 July. Analysis.

160720
CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis
Kojima Y, Volkmer J-P,  McKenna K, Civelek, Lusis AJ, Miller CL, Direnzo D, Nanda V, Ye J, Connolly AJ, Schadt EE, Quertermous T, Betancur P,  Maegdefessel L, Perisic Matic L , Hedin U, Weissman IL, Leeper NJ.
Nature (2016) Online 20 July. Letter.
På KI Nyheter: Antikroppar mot tumörer kan förhindra hjärtinfarkt och stroke

160719
Effects of alteplase on survival after ischaemic stroke (IST-3): 3 year follow-up of a randomised, controlled, open-label trial
Berge E, Cohen G, Roaldsen M, Lundström E, Isaksson E, Rudberg A-S, Bruins Slot K, Forbes J, Smith J, Drever J, Wardlaw J, Sandercock P, Whiteley
The Lancet Neurology (2016) Online 19 July. Article.

160714
Cloche is a bHLH-PAS transcription factor that drives endothelial and hematopoietic specification
Reischauer S, Stone OA, Villasenor A et al.
Nature (2016) Online 14 July. Letter. 

160706
The global burden of viral hepatitis from 1990 to 2013: findings from the Global Burden of Disease Study 2013.
Stanaway JD, Flaxman AD, Naghavi M et al.
The Lancet (2016). Online July 6. Article.

160705
Use of evidence based practices to improve survival without severe morbidity for very preterm infants: results from the EPICE population based cohort 
Zeitlin J, Manktelow BN, Piedvache A et al.
BMJ (2016) Online 5 July. Research.
Vetenskaplig kommentar: Lost in translation – evidence to improve outcomes of very preterm infants

160701
The role of enhancers in cancer
Sur I, Taipale J
Nature Reviews Cancer (2016). Online 1 July. Review.

160701
Patient focused registries can improve health, care, and science
Nelson EC, Dixon-Woods M, Batalden PB, Homa K, Van Citters AD,
Morgan TS, Eftimovska E, Fisher ES, Ovretveit J,  Harrison W,  Lind C, Lindblad S
BMJ (2016) Online 1 July. Analysis.  

160701
Visualization and analysis of gene expression in tissue sections by spatial transcriptomics
Ståhl PL, Salmén F, Vickovic S, Lundmark A, Fernández Navarro J, Magnusson J, Giacomello S, Asp M, Westholm JO, Huss M, Mollbrink A, Linnarsson SCodeluppi S, Borg Å, Pontén F, Costea PI, Sahlén P, Mulder J, Bergmann O, Lundeberg J, Frisén J
Science (2016) Online 1 July. Report
På KI Nyheter: Ny metod ger bättre information om vilka gener som är aktiva

160628
Transmission of Neurodegenerative Disorders Through Blood Transfusion: A Cohort Study
Edgren G, Hjalgrim H, Rostgaard K, Lambert P, Wikman A, Norda R, Titlestad K-E, Erikstrup C, Ullum H, Melbye M, Busch MP, Nyrén O
Annals of Internal Medicine (2016) Online 28 June. Original Research.
På KI Nyheter: Ingen risk för demenssjukdom genom blodtransfusion

160627
Single-cell 5hmC sequencing reveals chromosome-wide cell-to-cell variability and enables lineage reconstruction
Mooijman D, Dey SS, Boisset J-C, Crosetto N, van Oudenaarden A
Nature Biotechnology (2016) Online 27 June. Letter.

160620
Life Expectancy of Patients With Chronic Myeloid Leukemia Approaches the Life Expectancy of the General Population
Bower HBjörkholm MDickman PWHöglund M, Lambert PC, Andersson TML
Journal of Clinical Oncology (2016) Online 20 June. Original report.

160620
Ovarian Cancer Risk Factors by Histologic Subtype: An Analysis From the Ovarian Cancer Cohort Consortium
Wentzensen N, Poole EM, Trabert B et al.
Journal of Clinical Oncology (2016) Online 20 June. Original Report.

160620
Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing
Galanos P, Vougas K, Walter D et al.
Nature Cell Biology (2016) Online 20 June. Article.

160620
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
Gormley P, Anttila V, Winsvold BS et al.
Nature Genetics (2016) Online 20 June. Article.

160614
Cardiovascular Events Associated with use of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia. A Population-Based Cohort Study
Dahlén T, Edgren G, Lambe M, Höglund M, Björkholm M, Sandin F, Själander A, Richter J, Olsson-Strömberg U, Ohm L, Bäck M, Stenke L
Annals of Internal Medicine (2016) Online 14 Juni. Original Research.

160614
Exercise Promotes Healthy Aging of Skeletal Muscle
Cartee GD, Hepple RT, Bamman MM, Zierath JR
Cell Metabolism (2016) Online 14 June. Perspective.

160609
Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system
Marques S, Zeisel A, Codeluppi S, van Bruggen D, Mendanha Falcão A, Xiao L, Huiliang L, Häring M, Hochgerner H, Romanov RA, Gyllborg D, Muñoz Manchado A, La Manno G, Lönnerberg PFloriddia EM, Rezayee F, Ernfors P, Arenas EHjerling-Leffler J, Harkany T, Richardson WD, Linnarsson S, Castelo-Branco G
Science (2016) Online 9 June. Report. 
På KI Nyheter: Nervisolerande celler mer olika varandra än man tidigare trott

 

160606
Age- and Tumor Subtype–Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers
Schmidt MK, Hogervorst F, van Hien R et al.
JCO (2016) Online 6 June. Original Report.

160606
Comparative Effectiveness of Treatment Strategies for Bladder Cancer With Clinical Evidence of Regional Lymph Node Involvement
Galsky MD, Stensland K, Sfakianos JP, Mehrazin R, Diefenbach M, Mohamed N, Tsao C-K,  Boffetta P, Wiklund P, Oh WK, Mazumdar M,  Ferket B

JCO (2016) Online 6 June. Original Report.

160606
Loss of the corepressor GPS2 sensitizes macrophage activation upon metabolic stress induced by obesity and type 2 diabetes
Fan R, Toubal A, Goñi S, Drareni K, Huang Z, Alzaid F, Ballaire R, Ancel P, Liang N, Damdimopoulos A, Hainault I, Soprani A, Aron-Wisnewsky J, Foufelle F, Lawrence T, Gautier J-F, Venteclef N, Treuter E
Nature Medicine (2016) Online 6 June. Article.
På KI Nyheter: Förändringar i epigenomet bidrar till fetma-associerad diabetes

160603
Drugging DNA Repair – Inhibiting DNA repair can have a positive outcome for various therapeutic interventions
Jackson SP, Helleday T
Science (2016) Online 3 June. Perspective.

160530
Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition
Vaccari M, Gordon SN, Fourati S et al.
Nature Medicine (2016) Online 30 May. Article.

160526
The neuroscience of working memory capacity and training
Constantinidis C, Klingberg T
Nature Reviews Neuroscience (2016) Online 26 May. Review.

160525
Proteogenomics connects somatic mutations to signaling in breast cancer
Mertins P, Mani DR, Ruggles KV et al.
Nature (2016) Online 25 May. Article.

160523
Deep sequencing of the MHC region in the Chinese population contributes to studies of complex
Zhou F, Cao H, Zuo X et al.
Nature Genetics (2016) Online 23 May. Article.

160516
A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases
Han B, Pouget JP, Slowikowski K et al.
Nature Genetics (2016) Online 16 May. Technical Report.

160509
Protection against malaria at 1 year and immune correlates following PfSPZ vaccination
Ishizuka AS, Lyke KE, DeZure A et al.
Nature Medicine (2016) Online 9 May. Article.

160502
Five endometrial cancer risk loci identified through genome-wide association analysis
Cheng THT, Thompson DJ, O'Mara TA et al.
Nature Genetics (2016) Online 2 May. Letter.

160502 
Origin, fate and dynamics of macrophages at central nervous system interfaces
Goldmann T, Wieghofer P, Costa Jordão MJ et al
Nature Immunology (2016) Online 2 May. Article.

160501
Fundamentals of Neurogastroenterology: Physiology/Motility – Sensation
Boeckxstaens G, Camilleri M, Sifrim D, Houghton LA, Elsenbruch S, Lindberg G, Azpiroz F, Parkman HP
Gastroenterology (2016) Online 1 May. Original research article.

Publikation