Karolinska Institutet Discovers

The purpose of the KI Discovers series is to give insight into the latest scientific achievements across a variety of disciplines at Karolinska Institutet by highlighting new publications and recent international recruitments. The seminar series is funded by the Board of Research and hosted by Junior Faculty, with administrative support of the Communications and Public Relations Office at KI. 

The seminars are held in either Nobel Forum, Campus Solna or Hörsalen Novum, Campus Flemingsberg or Venen, Danderyds sjukhus between 12.00-13.00. (Except for the lecture on 13 September which will be held at 10.30). Coffee and sandwich is served at 11.30. After the seminar, there is time for discussions. No registration is needed. 

Seminars autumn 2017

Wednesday 6 September

Professor Richard Rosenquist Brandell, was recently appointed Professor of Clinical Genetics at the Department of Molecular Medicine and Surgery, Karolinska Institutet and Senior Physician in Clinical Genetics at Karolinska University Hospital. 

He will talk about his group’s experience in applying next-generation sequencing technologies to decipher the genomic landscape of chronic lymphocytic leukemia and outline his future research plans at KI.

Title: "Charting the genomic landscape in chronic lymphocytic leukemia"

Reference paper for further reading: Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations. Blood. 2016 

The seminar will be held in Nobel Forum, Solna.

Wednesday 13 September at 10.30 am

Senior researcher Anna Rising and Professor Janne Johansson, both at the Department of Neurobiology, Care Sciences and Society

Biomimetic spinning of artificial spider silk from a chimeric minispidroin, Nature Chemical Biology, January 2017

Efficient protein production inspired by how spiders make silk, Nature Communications, May 2017

The seminar will be held in Lecture Hall Novum, Flemingsberg at 10.30-11.30. Lunch will be served after the lecture.

Wednesday 20 September

Associate Professor Jakob Michaelsson, Department of Medicine, Flemingsberg

Title: Natural killer cells in the human lung

Human lung natural killer cells are predominantly comprised of highly differentiated hypofunctional CD69-CD56dim cells, The journal of Allergy and Clinical Immunology, April 2017 

The seminar will be held in Lecture Hall Novum, Flemingsberg.

Wednesday 27 September

Professor Yihai Cao, Department of Microbiology, Tumor and Cell Biology

Title: Targeting angiogenesis for treatment of obesity and metabolic disease

Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat, Nature Communications, August 2016

The seminar will be held in Venen, house 18, 5th floor, Danderyds sjukhus

Wednesday 4 October

Professor Ernest Arenas, Department of Medical Biochemistry and Biophysics

Title: Decoding and reprogramming midbrain dopaminergic neurons for Parkinson’s disease cell replacement therapy

Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson’s disease model, Nature Biotechnology, May 2017

The seminar will be held in Nobel Forum, Solna.

Wednesday 11 October

Associate Professor Goncalo Castelo-Branco, Department of Medical Biochemistry and Biophysics

Title: Transcriptional and epigenetic states of oligodendrocyte lineage cells

Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system, Science, June 2016

The seminar will be held in Nobel Forum, Solna.

Wednesday 18 October

Professor Knut Lönnroth, newly recruited to the Department of Public Health Sciences. 

He will talk about his past findings in the field of social determinants and consequences of tuberculosis, discuss how they relate to the World Health Organization´s new global tuberculosis strategy and the Sustainable Development Goals, and outline his future research plan at Karolinska Institutet.

Title: Rediscovering the role of health care in social protection: The case of tuberculosis

Reference papers for further reading: 

The impact of social protection on tuberculosis rates: a global analysis, The Lancet ID, 2016

Beyond UHC: monitoring health and social protection coverage in the context of tuberculosiscare and prevention, PLoS Med, 2014

Financial burden for tuberculosis patients in low- and middle-income countries: a systematic review. Eur Respir J, 2014

The seminar will be held in Lecture Hall Novum, Flemingsberg.

Wednesday 25 October

Assistant Professor Laura Baranello, newly recruited to the Department of Cell and Molecular Biology

She will talk about her past findings in the field of DNA topology, chromatin and transcription regulation and outline her future research plan at Karolinska Institutet where she aims to study how topoisomerases are regulated during DNA transactions with the goal to discover new strategies for cancer treatment.

Title: Topoisomerase, DNA topology and chromatin: a new twist on genome function

RNA Polymerase II Regulates Topoisomerase 1 Activity to Favor Efficient Transcription, Cell, April 2016

The seminar will be held in Nobel Forum, Solna.

Wednesday 8 November

Senior researcher Johan Björkegren, Department of Medicine, Flemingsberg

Title: Network biology of cardiometabolic disease - from hairballs to key disease drivers - A Systems Genetics Approach

Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases, Science, August 2016

 The seminar will be held in Nobel Forum, Solna.

Wednesday 15 November

Professor Anca Catrina, Department of Medicine, Solna

Title: From triggering to targeting in autoimmune diseases: the case of rheumatoid arthritis.

How well do ACPA discriminate and predict RA in the general population: a study based on 12 590 population-representative Swedish twins, BMJ, April 2016

The seminar will be held in Nobel Forum, Solna.

Wednesday 22 November

Associate Professor Liv Eidsmo, Department of Medicine, Solna

Title: In human skin, CD49a marks resident T cells poised to cytotoxicity with clinical implications for vitiligo.

CD49a Expression Defines Tissue-Resident CD8(+) T Cells Poised for Cytotoxic Function in Human Skin, Immunity, February 2017

The seminar will be held in Nobel Forum, Solna.

Wednesday 29 November

Postdoc Ashley Nordsletten, Department of Clinical Neuroscience

 Patterns of Nonrandom Mating Within and Across 11 Major Psychiatric Disorders, JAMA Psychiatry, February 2016

The seminar will be held in Nobel Forum, Solna.

 

 

Seminars spring 2017

Wednesday 5 April

Professor Harri Alenius, Institute of Environmental Medicine, will present the research behind his publication:

Inhalation and Oropharyngeal Aspiration Exposure to Rod-Like Carbon Nanotubes Induce Similar Airway Inflammation and Biological Responses in Mouse Lungs, ACS Nano, January 2017. Kinaret P, Ilves M, Fortino, V, Rydman E, Karisola P, Lähde A, Koivisto J, Jokiniemi, Wolff H, Savolainen K, Greco D and Alenius H.

The seminar will be held in Lecture Hall Novum, Flemingsberg.

Wednesday 12 April

Professor Randall Johnson, Department of Cell and Molecular Biology, will present the research behind his publication:

S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate,
Nature, October 2016.
Tyrakis P, Palazon A, Macias D, Lee K, Phan A, Veliça P, You J, Chia G, Sim J, Doedens A, Abelanet A, Evans C, Griffiths J, Poellinger L, Goldrath A and Johnson R.

Read the web news: Self-renewable killer cells could be key to making cancer immunotherapy work

The seminar will be held in Nobel Forum, Solna.

Wednesday 19 April

Professor Sven Cnattingius, Department of Medicine, Solna and Assistant Professor Kristina Tedroff, Department of Women's and Children's Health will present the research behind their publications:

Association Between Maternal Body Mass Index in Early Pregnancy and Incidence of Cerebral Palsy,
JAMA, March 2017.
Villamor E, Tedroff K, Peterson M, Johansson S, Neovius MPetersson G and Cnattingius S.

Maternal Body Mass Index in Early Pregnancy and Risk of Epilepsy in Offspring
JAMA Neurology, April 2017.
Razaz N, Villamor E, Tedroff K and Cnattingius S.

The seminar will be held in Nobel Forum, Solna.

Wednesday 26 April

Professor Thomas Perlmann, Department of Cell and Molecular Biology, will present the research behind his publication:

Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages,
Cell Stem Cell, October 2016.
Kee N, Volakakis N, Kirkeby A, Dahl L, Storvall H, Nolbrant S, Lahti L, Björklund Å, Gillberg L, Joodmardi E, Sandberg R, Parmar M och Perlmann T.

The seminar will be held in Nobel Forum, Solna.

Wednesday 10 May

Professor Maria Albin, newly recruited to the Institute of Environmental Medicine, will talk about her past findings in the field of Occupational and Environmental Medicine and outline her future research plan at Karolinska Institutet.

Title: “A sustainable working-life for all”.

Reference paper for further reading: Occupation, gender and work-life exits: a Swedish population study,
Ageing & Society, March 2017.
Kadefors R, Nilsson K, Rylander L, Östergren PO and Albin M.  

The seminar will be held in Lecture Hall Novum, Flemingsberg.

Wednesday 17 May

Doctor Magdalena Paolino, newly recruited as Assistant Professor to the Department of Medicine, Solna, will talk about her past findings in the field of ubiquitination and outline her future research plan at Karolinska Institutet. 

Title: "Targeting ubiquitination to awaken immune responses against cancer metastasis".

Reference paper for further readingThe E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells,
Nature, February 2014.
Paolino M, Choidas A, Wallner S, Pranjic B, Uribesalgo I, Loeser S, Jamieson A.M, Langdon W.Y, Ikeda F, Fededa J. P, Cronin S. J, Nitsch R, Schultz-Fademrecht C, Eickhoff J, Menninger S, Unger A. Torka R, Gruber T, Hinterleitner R, Baier G, Wolf D, Ullrich A, Klebl B. M and Penninger J. M.

The seminar will be held in Nobel Forum, Solna.

Mission statement and archive

Since 2012, the KI Discovers seminars have presented excellent research conducted at this university. The seminar series was founded by Professor Mats Wahlgren, at the time KI’s Pro-Dean of Research. As from 2017, Junior Faculty at KI is hosting the seminar series, with Assistant Professor Kristiina Tammimies currently leading the programme committee. 

View the programmes from previous years

View Junior Faculty's misstion statement for KI Discovers

Contact

Programme committee of KI Discovers: ki-discovers@ki.se

Questions? Contact: Sabina Giulini, Communications and Public Relations Office