KIRCNET mini-symposium

In the beginning of 2012, KIRCNET initiated a series of mini-symposia aiming to faciliate collaborations between pre-clinical and clinical researchers in the cardiovascular and pulmonary area together.

The purpose of this symposium series is to create an creative, inspiring and relaxing environment for clinical and preclinical researchers to meet each other for discussing exciting ongoing research, but also show good examples about how to initiate and build a research career in a patient-centered research and not least how to take research into patient benefit.
Mini-symposia highlights these research with three types of presentations:

  • A research presentation by a scientist working in a translational research environment
  • A short statement of one of KIRCNETs travel grant recipients who shares about his/her stay abroad (techniques acquired or collaboration as a whole) 
  • An inspirational lecture in science and innovation

You can find the programme and photos from our previous mini-symposia here.


KIRCNET Mini-symposium on Pulmonary Hypertension (5 April 2016)

Pulmonary hypertension-a primer to clinicians and vascular biologists
Speaker: Professor Vinicio de Jesus Perez, Stanford University Medical Center
Pulmonary arterial hypertension (PAH) is a devastating disease associated with small vessel obstruction and progressive right heart failure with a median survival of 3 years.  While the etiology of PAH is unknown, the last 15 years have seen major discoveries that provide hope for future curative therapies.  We will review the clinical manifestations and pathogenesis of pulmonary arterial hypertension, focusing on recent discoveries in genetics and cellular biology.  We will also present research looking at how anomalies in endothelial cell and pericyte communication contributes to small vessel loss and development of PAH.

Extracellular matrix and growth factor regulation in pulmonary hypertension
Speaker: Karin Tran Lundmark, Karolinska Institutet & Lund University
Extracellular matrix proteoglycans may be of importance for the pathogenesis of pulmonary arterial hypertension due to their ability to bind growth factors and cytokines. Depending of their localization in the extracellular space they may either sequester growth factors, and thereby restrict their activity, or present growth factors to cell-surface receptors. Novel findings from animal models as well as human data will be discussed. 


Novel methods and applications in cardiovascular disease (19 Nov 2014)

Speaker: Professor Ulf Hedin
Title: Carotid plaque instabiltiy and stroke - From Man to Molecule 

Speaker: Professor Joakim Lundeberg
Title: Spatial Transcriptomics - massive in situ analysis of gene expression


Mini-symposium: Regenerative Medicine in Cardiovascular Disease (8 Apr 2013)

Speaker: Kenneth Chien, Professor, Department of Cell and Molecular Biology
Title: A Map for Cardiovascular Regenerative Medicine

Speaker: Karl-Henrik Grinnemo, MD PhD, Department of Molecular Medicine and Surgery
Title: Cardiac progenitors for myocardial repair - from bench to patient

Moderator: Lars Lund, MD PhD


Mini-symposium (12 Sep 2012)


Speaker: Magnus Bäck, Cardiology Unit, KS andDepartment of Medicine Solna, KI
Title: Leukotrienes in cardiovascular disease - from bench to bedside
Moderator: Anders Franco-Cereceda, Professor


Speaker: Ya-Ting Chang and Philip Tannenberg, Department of Molecular Medicine and Surgery, KI - Recipient of KIRCNET travel grant -
Title: Rodent model of hypoxia-induced pulmonary hypertension and hemodynamic measurement
Moderator: Aristomenis Manouras, MD PhD


Speaker: Bo-Ragnar Tolf, Director of KI Innovation Office
Title: The KI Innovation System - meeting the challenges in a changing world
Moderator: Caroline Olgart Höglund, Associate Professor


Mini-symposium (13 Nov 2012)


Speaker: Erik Ingelsson, Professor of Cardiovascular Epidemiology, Department of Medical Epidemiology and Biostatistics
Title: Large-scale molecular methods in cardiovascular research


Speaker: Bianka Karshikoff, Department of Clinical Neuroscience - Recipient of KIRCNET travel grant -  
Title: Sickness hurts: Pain sensitivity during experimentally induced systemic inflammation


Speaker: Michael Sundström, Karolinska Development
Title: Private-Public Joint Ventures in Early Drug Discovery – Current and Future Models


Mini-symposium (24 Jan 2012)

On January 24th 2012, KIRCNET organized the first mini-symposium in the Faculty Club at Karolinska University Hospital. Three lectures were followed by a mingling with free drinks and snacks. The symposium gathered around 70 participants from the different departments and gave an excellent opportunity for scientists to get to know each other and to discuss mutual interests in a relaxed atmosphere.

Felix Böhm, who is both a cardiologist in the Karolinska Hospital and a scientist at the Center for Molecular Medicine, gave a lecture about his research on endothelial function and oxidative stress in coronary artery disease. He also shared his experience that he obtained in Oxford during the postdoc period.

Ola Nilsson, the PhD student from the Clinical Immunology and Allergy Unit at KI, talked about his scientific exchange trip to the Swiss Institute of Allergy and Asthma Research in Davos, Switzerland. The trip was financed by KIRCNET travel grant in 2011 and allowed Ola to learn the methodology of the phage display technique, as well as the methods of creating a phage display library.

Roman Zubarev, the professor at the Department of Medical Biochemistry and Biophysics at KI, gave a very apprehensible introduction on how to apply mass spectrometry to the clinical research.

The KIRCNET steering group thanks all lecturers and participants for helping to make the first mini-symposium successful. We are looking forward to meeting your next time!