Epidemiology and Public Health Intervention Research (EPHIR)

The research group aims at conducting high quality research within the area of public health epidemiology, especially applied to the evaluation of public health interventions.

Research areas

Research projects encompass descriptive, analytical as well as experimental studies in both community and institutional settings, with particular focus on social, behavioral and lifestyle factors of importance for human health during the whole life span. Also, studies rest on a variety of data sources, involving ad-hoc surveys, population-based registers, as well as biologic samples, particularly molecular genetics. 


There are ongoing national collaborations within KI and external with Occupational health, Uppsala, Center for Social research on Alcohol and Drugs and Centre for Equity Studies (CHESS), Stockholm University, and many other academic institutions. An important partner is the Centre for Epidemiology and Community Health of Stockholm County Health Care District (CES), where several of the group researchers have part-time commitments.

Internationally the group holds collaborations with Helsinki University, Oxford Brookes and Sheffield University (UK) and Avogadro University (IT).

The group is among the promoters of the European Society of Prevention Research (EUSPR) and of the SPAN (Science for Prevention Academic Network), funded by the Erasmus Lifelong Learning Program.


The group are actively involved in education at all levels and includes the responsible for the undergraduate education (GUA) at the Department of Public Health Sciences and the director of studies for the Public Health Epidemiology track in Public Health. 


Currently the group has grants from Vårdal, FAS/Forte, HjärtLungfonden, Länsförsäkringar, FORMAS, Folkhälsoinstitutet, European Comission and VR.

Ongoing research projects

KUPOL - The KUPOL Study on mental health in adolescence.
PART - Study on risk and protective factors for mental health. 
REGASSA - a randomized controlled trial of internet-based cognitive behavioral therapy, physical activity and treatment as usual in mild to moderate depression.

Study protocols

REGASSA - Fit For Life

Doctoral theses

Doctoral theses defended the last 5 years

 Tobacco Use and Dependence - Does it Originate in Utero?
  Mina Rydell, Date: 2014-03-21 
Social Environment and Genetics as Determinants of Depression Occurrence and Its Chronicity: A Longitudinal Survey
Carlos Andrés Fandiño-Losada, Date: 2013-04-16 
 Triggers of Sick Leave - Epidemiological Studies of Work-Related Factors
 Hanna Hultin, Date: 2011-05-27 

Scientific publications

Publication Author

Path analysis of the chronicity of depression using the comprehensive developmental model framework. ISSN: 0803-9488 

Fandino-Losada A, Bangdiwala S I, Lavebratt C, Forsell Y.

The validity of the Symptom Checklist Depression and Anxiety subscales: a general population study in Sweden. Journal of Affective Disorders May 2015 DOI:10.1016/j.jad.2015.05.024

 Lundin A, Hallgren M, Forsell Y.

Anti-social behaviors associated with Anabolic-Androgenic Steroid use and with other illicit drug use among adolescent boys: a cross-sectional study. Eur Addict Res Jun 2015;21:321–326 DOI: 10.1159/000433580

Hallgren M, Pope HG, Kanayama G, Hudson JI, Lundin A, & Källmén H. 

Physical exercise and internet-based cognitive behavioural therapy in the treatment of depression: randomized controlled trial. The British Journal of Psychiatry Jun 2015, DOI: 10.1192/bjp.bp.114.160101

Hallgren M, Kraepelien M, Öjehagen A, Lindefors N, Zeebari Z, Kaldo V, Forsell Y.

Evaluation of a brief counseling for tobacco cessation in dental clinics among Swedish smokers and snus users. A cluster randomized controlled trial (the FRITT study), Volume 70, January 2015, Pages 26–32.

Virtanen SE, Zeebari Z, Rohyo I, Galanti M R.

Increased screening of alcohol habits among patients with depression is needed. Scand J Public Health. 2014 Nov;42(7): 658-9. 1.

Hallgren M, Ahlin J, Forsell Y, Ojehagen A. 

Social factors in childhood and risk of depressive symptoms among adolescents – a longitudinal study in Stockholm, Sweden. Int J Equity Health. 2014 Nov 11;13(1):96. 

Wirback T, Möller J, Jan-Olov Larsson J-O, Galanti M R, Engström K. 

Medication and fall injury in the elderly population. Do individual demographics, health status and lifestyle matter? BMC Geriatrics 2014;14:92. 

Helgadóttir B, Laflamme L, Monárrez-Espino J, Möller J. 

Systematic review of the effect of pictorial warnings on cigarette packages in smoking behaviour. Am J Public Health. 2014 Oct;104(10):e11-30. 

Monarrez-Espino J, Bojing L, Bremberg S, Galanti M R. 

School policies for preventing smoking among young people. Cochrane Database of Systematic Reviews 2014, Issue 10. Art. No.: CD009990. DOI: 10.1002/14651858.CD009990.pub2. 

Coppo A,Galanti M R,Giordano L,Buscemi D,Bremberg S, Faggiano F. 

The use of AUDIT in detecting alcohol use disorder and risk drinking in the general population: validation of AUDIT using Schedules for Clinical Assessment in Neuropsychiatry. Alcohol Clin Exp Res. (Accepted 2014-10-02).

 Lundin A, Hallgren M, Balliu N, Forsell Y.

An evaluation of long-term changes in alcohol use and alcohol problems among clients of the Swedish National Alcohol Helpline. Substance Abuse Treatment, Prevention, and Policy, 2014; 9:22.

Heinemans N, Toftgård M, Damström-Thakker K, Galanti M R.

Impact of expectations on the effects of exercise on psychological distress. American Journal of Health Behavior. 2014 Sep;38(5):650-6. 

Helgadottir B, Ekblom Ö, Forsell Y. 

Use of water-pipe is associated to other substance use among adolescents. Results from a national survey in Sweden. Nicotine & Tobacco Research, 2014 Aug 18.

Galanti M R, Al-Adhami M. 

The risk of fall injury in relation to commonly prescribed medications among older people-a Swedish case-control study. Eur J Public Health. 2014 Jul 31. pii: cku120. 

Kuschel B M, Laflamme L, Möller J. 

Youth alcohol polarization effects in regional but not national data. Addiction. 2014 Aug;109(8):1384-5.

 Hallgren M. 

The psychometric properties of the AUDIT: a survey from a random sample of elderly Swedish adults. BMC Public Health. 2014 Jul 1;14:672. 

Källmén H, Wennberg P, Ramstedt M, Hallgren M. 

Yoga as an adjunct treatment for alcohol dependence: a pilot study. Complement Ther Med. 2014 Jun;22(3):441-5. 

Hallgren M, Romberg K, Bakshi AS, Andréasson S. 

The influence of CYP2D6-inhibiting drugs on the risk of newly initiated opioid treatment on fall-related injuries - a Swedish register-based case-crossover study. (Basic and Clinical Pharmacology & Toxicology, accept June 2014).

Möller J, Laflamme L, Söderberg KL. 

The role of marital status in the association between benzodiazepines,psychotropics and injurious road traffic crashes: a register-based nationwide study of senior drivers in Sweden. PLoS One. 2014;29;9(1):e86742. 

Johnell K, Laflamme L, Möller J, Monárrez-Espino J. 

"Unplugged," a European school-based program for substance use prevention among adolescents: Overview of results from the EU-Dap trial. New Dir Youth Dev. 2014 Mar;2014(141):67-82. doi: 10.1002/yd.20087.PMID:24753279.

Vigna-Taglianti FD, Galanti MR, Burkhart G, Caria MP, Vadrucci S, Faggiano F.

Number of medications and road traffic crashes in senior Swedish drivers: a population-based matched case-control study. Inj Prev. 2014;20(2):81-87.

Monárrez-Espino J, Laflamme L, Elling B, Möller J. 

An association between initiation of selective serotonin reuptake inhibitors and suicide - a nationwide register-based case-crossover study. PLoS One. 2013;8(9):e73973.

Björkenstam C, Möller J, Ringbäck G, Salmi P, Hallqvist J, Ljung R. 

Analgesics and road traffic crashes in senior drivers: an epidemiological review and explorative meta-analysis on opioids. Accid Anal Prev. 2013;57:157-64.

Monárrez-Espino J, Möller J, Berg HY, Kalani M, Laflamme L. 

Lack of adjustment latitude at work as a trigger of taking sick leave-a Swedish case-crossover study. PLoS One. 2013 Apr 19;8(4):e61830.

Hultin H, Hallqvist J, Alexanderson K, Johansson G, Lindholm C, Lundberg I, Möller J. 

Demands, skill discretion, decision authority and social climate at work as determinants of major depression in a 3-year follow-up study.
ISSN: 0340-0131 ; E-ISSN: 1432-1246 ; DOI: 10.1007/s00420-012-0791-3 

Fandiño-Losada A, Forsell Y, Lundberg I.

Working conditions, serotonin transporter gene polymorphism (5-HTTLPR) and anxiety disorders: A prospective cohort study
ISSN: 0165-0327 ; DOI: 10.1016/j.jad.2013.07.013 

Liu B, Lavebratt C, Nordqvist T, Fandiño-Losada, A, Theorell T, Forsell Y, Lundberg I.

Stress as a trigger for relapses in IBD - A case-crossover study. Gastroenterology Research 2013;6(1):10-16.

Jäghult J, Saboonchi F, Möller J, Johansson UB, Wredling R, Kapraali M. 

Job insecurity and prognosis after myocardial infarction: the SHEEP Study. Int J Cardiol 2013;167(6):2824-30.

László K, Engström K, Hallqvist J, Ahlbom A,  Janszky I. 

Unlicensed driving and other related health risk behaviors:  A study of Montana high school students. Accid Anal Prev. 2013;54:26-31.

Hanna C, Laflamme L, Möller J. 

Newly initiated opioid treatment and the risk of fall-related injuries. A nationwide, register-based, case-crossover study in Sweden. CNS Drugs. 2013;27(2):155-61.

Söderberg KC, Laflamme L, Möller J. 

The triggering effect of alcohol and illicit drugs on violent crime in a remand prison population: a case crossover study. Drug Alcohol Depend. 2013;129(1-2):110-5.

Lundholm L, Haggård U, Möller J, Hallqvist J, Thiblin I. 

Influence of serotonin transporter promoter variation on the effects of separation from parent/partner on depression. 
ISSN: 0165-0327 ; DOI: 10.1016/j.jad.2012.06.034 

Fandiño-Losada A, Wei Y, Åberg E, Sjöholm L K., Lavebratt C,  Forsell Y.

The functional Val 158Met polymorphism in catechol-O-methyltransferase (COMT) is associated with depression and motivation in men from a Swedish population-based study.  ISSN: 0165-0327 ; DOI: 10.1016/j.jad.2010.08.009 

 Åberg E, Fandiño-Losada A, Sjöholm L K.,Forsell Y, Lavebratt C.

Group members

Alexandra PantzarAssociated
Alicia NevrianaResearch assistant
Anna MånsdotterAssociated
Annika PalmqvistResearch assistant
Arun John Saldanha ShetGraduate Student
Aya NakitandaResearch assistant
Aysha AlmasGraduate Student
Bereket LodeboResearch assistant
Björg HelgadottirPhD student, Graduate Student
Carla NooijenPostdoc
Charisse JohnsonGraduate Student, Research assistant
Elena RaffettiAssociated
Eleonor SäfstenPhD student, Graduate Student
Elin ArnöResearch coordinator
Erik KinnmanAssociated
Filip AnderssonStatistician
Hanna HultinAssociated
Imre JanszkyAssociated
Jette MöllerAssociate professor
Karin EngströmLecturer senior, adjunct
Katalin GémesPhD student, Graduate Student
Krisztina LászlóAssistant professor
Malin PetterssonAssociated
Mats HallgrenEmployee
Melody AlmrothGraduate Student, Research officer
My RiseidResearch officer
Rosaria GalantiAdjunct professor
Sinziana-Ioana OncioiuAssociated
Sofia MuradResearch officer
Staffan AhnveAssociated
Suvi VirtanenAssociated
Therese WirbackPhD student, Graduate Student
Veronika TiradoEducational assistant
Vladimirs SavecsResearch assistant
Yajun LiangAssistant professor
Yvonne ForsellAdjunct professor
Zangin ZeebariAssociated

Contact us

Adjunct professor

Yvonne Forsell

Phone: 08-123 371 61
Organizational unit: Department of Public Health Sciences (PHS), K9
E-mail: Yvonne.Forsell@ki.se

Intervention researchSocial Medicine