Weng-Onn Lui

About me
Publications
CV
Public outreach and news

About me

Current position
Associate professor (molecular genetics), since Jan 2014
Research fellow (VR Rådsforskare), September 2010 – August 2016, 100%
research
* Travel awards from Karolinska Institutet Foundation (2001), Swedish Cancer
Foundation and the Cancer Society in Stockholm (2002, 2003, 2004)
* AACR-Ortho Biotech Scholar-in-Training Award (2003)
* AACR-AFLAC Scholar-in-training award (2005, 2006)
* Translational Research Award, Stanford Comprehensive Cancer Center (2007)
* Swedish Research Council Junior Fellowship (2008, 4 years)
* Swedish Research Council Senior Fellowship (2010, 6 years)
* 1992-1996, Tunku Abdul Rahman College, Malaysia, Bachelor of Science
(Applied Science)
* 1999–2002, Karolinska Institutet, Sweden, PhD (Medical Genetics)
Postdoctoral work
* Nov 2002-Aug 2004, Karolinska Hospital (Thyroid cancer
Advisor: Catharina
Larsson)
* Sep 2004-June 2008, Stanford University School of Medicine, USA (Advisor:
Andrew Fire)

Research

My primary research area is on small RNA biology. Our research activity is
mainly focusing on studying the role of small RNAs in cancer development and
drug resistance.
http://ki.se/ki/jsp/polopoly.jsp?d=44413&
a=156545&
l=en
A major effort of our previous work had focused on the identification of
novel small RNAs (particularly miRNAs) and the documentation of their
expression patterns in several tissue types. We also evaluated the potential
use of miRNA expression profiles in tumor classification and prognostication.
Our current projects focus primarily on the functional roles of small RNAs
along with their regulatory components in clinically relevant experimental
systems.

Articles

Article: CELLS. 2023;12(13):1682

Modulation of E-Cadherin Function through the AmotL2 Isoforms Promotes Ameboid Cell Invasion.

Subramani A; Cui W; Zhang Y; Friman T; Zhao Z; Huang W; Fonseca P; Lui W-O; Narayanan V; Bobrowska J; Lekka M; Yan J; Conway DE; Holmgren L
Article: DEVELOPMENTAL CELL. 2023;58(6):450-460.e6

A small noncoding RNA links ribosome recovery and translation control to dedifferentiation during salamander limb regeneration.

Subramanian E; Elewa A; Brito G; Kumar A; Segerstolpe Å; Karampelias C; Björklund Å; Sandberg R; Echeverri K; Lui W-O; Andersson O; Simon A
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2022;61(5):140

Altered expression of the IGF2‑H19 locus and mitochondrial respiratory complexes in adrenocortical carcinoma.

Scicluna P; Caramuta S; Kjellin H; Xu C; Fröbom R; Akhtar M; Gao J; Shi H; Kjellman M; Almgren M; Höög A; Zedenius J; Ekström TJ; Bränström R; Lui W-O; Larsson C
Article: BIOMEDICINE & PHARMACOTHERAPY. 2022;149:112796

Synergistic effects of telomerase reverse transcriptase and regulator of telomere elongation helicase 1 on aggressiveness and outcomes in adrenocortical carcinoma.

Yuan H; Wu Y; Wang J; Qin X; Huang Y; Yan L; Fana Y; Zedenius J; Juhlin CC; Larsson C; Lui W-O; Xu D
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(7):3702

The Merkel Cell Polyomavirus T-Antigens and IL-33/ST2-IL1RAcP Axis: Possible Role in Merkel Cell Carcinoma.

Rasheed K; Moens U; Policastro B; Johnsen JI; Koljonen V; Sihto H; Lui W-O; Sveinbjørnsson B
Article: ISCIENCE. 2021;24(11):103264

Merkel cell polyomavirus T-antigens regulate DICER1 mRNA stability and translation through HSC70.

Gao J; Shi H; Juhlin CC; Larsson C; Lui W-O
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(19):10600

Imatinib Regulates miR-483-3p and Mitochondrial Respiratory Complexes in Gastrointestinal Stromal Tumors.

Huang W-K; Shi H; Akçakaya P; Zeljic K; Gangaev A; Caramuta S; Yeh C-N; Bränström R; Larsson C; Lui W-O
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2021;557:14-19

Direct interaction of the ATP-sensitive K+ channel by the tyrosine kinase inhibitors imatinib, sunitinib and nilotinib.

Fröbom R; Berglund E; Aspinwall CA; Lui W-O; Nilsson I-L; Larsson C; Bränström R
Article: CANCERS. 2021;13(2):E265-265

Sex Differences in Overall Survival and the Effect of Radiotherapy in Merkel Cell Carcinoma-A Retrospective Analysis of a Swedish Cohort.

Björn Andtback H; Björnhagen-Säfwenberg V; Shi H; Lui W-O; Masucci GV; Villabona L
Article: CELLS. 2020;9(6):E1333-1333

Heterogeneity of Metabolic Vulnerability in Imatinib -Resistant Gastrointestinal Stromal Tumor.

Huang W-K; Gao J; Chen Z; Shi H; Yuan J; Cui HL; Yeh C-N; Bränström R; Larsson C; Li S; Lui W-O
Article: ENDOCRINE-RELATED CANCER. 2020;27(5):295-308

GABPA-dependent down-regulation of DICER1 in follicular thyroid tumours.

Paulsson JO; Wang N; Gao J; Stenman A; Zedenius J; Mu N; Lui W-O; Larsson C; Juhlin CC
Article: INTERNATIONAL JOURNAL OF CANCER. 2020;146(6):1652-1666

Merkel cell polyomavirus oncoproteins induce microRNAs that suppress multiple autophagy genes.

Kumar S; Xie H; Shi H; Gao J; Juhlin CC; Björnhagen V; Höög A; Lee L; Larsson C; Lui W-O
Article: ANTICANCER RESEARCH. 2019;39(7):3433-3442

Biochemical Inhibition of DOG1/TMEM16A Achieves Antitumoral Effects in Human Gastrointestinal Stromal Tumor Cells In Vitro.

Fröbom R; Sellberg F; Xu C; Zhao A; Larsson C; Lui W-O; Nilsson I-L; Berglund E; Bränström R
Article: CANCERS. 2018;10(11):E443-443

MiR-375 Regulation of LDHB Plays Distinct Roles in Polyomavirus-Positive and -Negative Merkel Cell Carcinoma.

Kumar S; Xie H; Scicluna P; Lee L; Björnhagen V; Höög A; Larsson C; Lui W-O
Article: EXPERIMENTAL CELL RESEARCH. 2018;371(1):287-296

miR-125a-5p regulation increases phosphorylation of FAK that contributes to imatinib resistance in gastrointestinal stromal tumors.

Huang W-K; Akçakaya P; Gangaev A; Lee L; Zeljic K; Hajeri P; Berglund E; Ghaderi M; Åhlén J; Bränström R; Larsson C; Lui W-O
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2018;16(4):791-801

Thrombin-reduced miR-27b attenuates platelet angiogenic activities in vitro via enhancing platelet synthesis of anti-angiogenic thrombospondin-1.

Miao X; Rahman MF-U; Jiang L; Min Y; Tan S; Xie H; Lee L; Wang M; Malmström RE; Lui W-O; Li N
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2018;52(1):55-66

MicroRNA expression profiles in non‑epithelial ovarian tumors.

Chang RK; Li X; Mu N; Hrydziuszko O; Garcia-Majano B; Larsson C; Lui W-O
Article: CELL DEATH & DISEASE. 2017;8(5):e2759

Loss of miR-514a-3p regulation of PEG3 activates the NF-kappa B pathway in human testicular germ cell tumors.

Özata DM; Li X; Lee L; Liu J; Warsito D; Hajeri P; Hultman I; Fotouhi O; Marklund S; Ährlund-Richter L; Juhlin CC; Larsson C; Lui W-O
Article: JOURNAL OF GENERAL VIROLOGY. 2017;98(5):1058-1072

Human cytomegalovirus microRNAs are carried by virions and dense bodies and are delivered to target cells.

Mohammad A-A; Costa H; Landázuri N; Lui W-O; Hultenby K; Rahbar A; Yaiw K-C; Söderberg-Nauclér C
Article: ONCOLOGY LETTERS. 2017;13(5):3586-3598

Evaluation of microRNA-205 expression as a potential triage marker for patients with low-grade squamous intraepithelial lesions.

Xie H; Norman I; Hjerpe A; Vladic T; Larsson C; Lui W-O; Östensson E; Andersson S
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2017;50(2):356-364

miR‑223‑3p regulates cell growth and apoptosis via FBXW7 suggesting an oncogenic role in human testicular germ cell tumors.

Liu J; Shi H; Li X; Chen G; Larsson C; Lui W-O
Article: ONCOTARGET. 2016;7(2):1895-1911

Genome-wide identification of Wig-1 mRNA targets by RIP-Seq analysis.

Bersani C; Huss M; Giacomello S; Xu L-D; Bianchi J; Eriksson S; Jerhammar F; Alexeyenko A; Vilborg A; Lundeberg J; Lui W-O; Wiman KG
Article: PLOS ONE. 2016;11(4):e0152032

Tissue and Serum miRNA Profile in Locally Advanced Breast Cancer (LABC) in Response to Neo-Adjuvant Chemotherapy (NAC) Treatment.

Al-Khanbashi M; Caramuta S; Alajmi AM; Al-Haddabi I; Al-Riyami M; Lui W-O; Al-Moundhri MS
Article: EXPERIMENTAL CELL RESEARCH. 2015;336(1):158-170

Secretome protein signature of human gastrointestinal stromal tumor cells.

Berglund E; Daré E; Branca RMM; Akcakaya P; Fröbom R; Berggren P-O; Lui W-O; Larsson C; Zedenius J; Orre L; Lehtiö J; Kim J; Bränström R
Article: INTERNATIONAL JOURNAL OF CANCER. 2015;136(5):E230-E241

Novel functions and targets of miR-944 in human cervical cancer cells.

Xie H; Lee L; Scicluna P; Kavak E; Larsson C; Sandberg R; Lui W-O
Article: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 2015;889:51-70

MicroRNAs and Gastrointestinal Stromal Tumor.

Akçakaya P; Lui W-O
Article: BRITISH JOURNAL OF CANCER. 2014;111(11):2091-2102

microRNA expression signatures of gastrointestinal stromal tumours: associations with imatinib resistance and patient outcome.

Akçakaya P; Caramuta S; Åhlen J; Ghaderi M; Berglund E; Östman A; Bränström R; Larsson C; Lui W-O
Article: ONCOTARGET. 2014;5(20):10048-10057

TERT promoter mutations and gene amplification: promoting TERT expression in Merkel cell carcinoma.

Xie H; Liu T; Wang N; Björnhagen V; Höög A; Larsson C; Lui W-O; Xu D
Article: ONCOGENE. 2014;33(35):4407-4417

Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3σ.

Bersani C; Xu L-D; Vilborg A; Lui W-O; Wiman KG
Article: EXPERIMENTAL CELL RESEARCH. 2014;326(2):315-325

Functional role of the Ca²⁺-activated Cl⁻ channel DOG1/TMEM16A in gastrointestinal stromal tumor cells.

Berglund E; Akcakaya P; Berglund D; Karlsson F; Vukojević V; Lee L; Bogdanović D; Lui W-O; Larsson C; Zedenius J; Fröbom R; Bränström R
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2014;170(4):583-591

MicroRNA expression patterns associated with hyperfunctioning and non-hyperfunctioning phenotypes in adrenocortical adenomas.

Velázquez-Fernández D; Caramuta S; Özata DM; Lu M; Höög A; Bäckdahl M; Larsson C; Lui W-O; Zedenius J
Article: ANTI-CANCER DRUGS. 2014;25(4):415-422

Intracellular concentration of the tyrosine kinase inhibitor imatinib in gastrointestinal stromal tumor cells.

Berglund E; Ubhayasekera SJKA; Karlsson F; Akcakaya P; Aluthgedara W; Ahlen J; Fröbom R; Nilsson I-L; Lui W-O; Larsson C; Zedenius J; Bergquist J; Bränström R
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2014;134(2):507-517

MicroRNA expression patterns related to merkel cell polyomavirus infection in human merkel cell carcinoma.

Xie H; Lee L; Caramuta S; Höög A; Browaldh N; Björnhagen V; Larsson C; Lui W-O
Article: PLOS ONE. 2014;9(12):e113740

Detection of circulating hcmv-miR-UL112-3p in patients with glioblastoma, rheumatoid arthritis, diabetes mellitus and healthy controls.

Mohammad A-A; Rahbar A; Lui W-O; Davoudi B; Catrina A; Stragliotto G; Mellbin L; Hamsten A; Rydén L; Yaiw K-C; Söderberg-Nauclér C
Article: DEVELOPMENTAL BIOLOGY. 2013;383(2):253-263

miR-128 regulates non-myocyte hyperplasia, deposition of extracellular matrix and Islet1 expression during newt cardiac regeneration.

Witman N; Heigwer J; Thaler B; Lui W-O; Morrison JI
Article: BLOOD CANCER JOURNAL. 2013;3(10):e152

Role of microRNAs and microRNA machinery in the pathogenesis of diffuse large B-cell lymphoma.

Caramuta S; Lee L; Ozata DM; Akçakaya P; Georgii-Hemming P; Xie H; Amini R-M; Lawrie CH; Enblad G; Larsson C; Berglund M; Lui W-O
Article: GENES CHROMOSOMES & CANCER. 2013;52(10):895-911

miRNA-214 is related to invasiveness of human non-small cell lung cancer and directly regulates alpha protein kinase 2 expression.

Salim H; Arvanitis A; de Petris L; Kanter L; Hååg P; Zovko A; Özata DM; Lui W-O; Lundholm L; Zhivotovsky B; Lewensohn R; Viktorsson K
Article: ENDOCRINE-RELATED CANCER. 2013;20(4):551-564

Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma.

Caramuta S; Lee L; Ozata DM; Akçakaya P; Xie H; Höög A; Zedenius J; Bäckdahl M; Larsson C; Lui W-O
Article: EXPERIMENTAL CELL RESEARCH. 2013;319(8):1229-1238

Evidence for Ca(2+)-regulated ATP release in gastrointestinal stromal tumors.

Berglund E; Berglund D; Akcakaya P; Ghaderi M; Daré E; Berggren P-O; Köhler M; Aspinwall CA; Lui W-O; Zedenius J; Larsson C; Bränström R
Article: NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2013;20(4):440-446

A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells.

Johnsson P; Ackley A; Vidarsdottir L; Lui W-O; Corcoran M; Grandér D; Morris KV
Article: PLOS ONE. 2012;7(10):e46990

miR-205 expression promotes cell proliferation and migration of human cervical cancer cells.

Xie H; Zhao Y; Caramuta S; Larsson C; Lui W-O
Article: ENDOCRINE-RELATED CANCER. 2011;18(6):643-655

The role of microRNA deregulation in the pathogenesis of adrenocortical carcinoma.

Özata DM; Caramuta S; Velázquez-Fernández D; Akçakaya P; Xie H; Höög A; Zedenius J; Bäckdahl M; Larsson C; Lui W-O
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2011;39(2):311-318

miR-185 and miR-133b deregulation is associated with overall survival and metastasis in colorectal cancer.

Akçakaya P; Ekelund S; Kolosenko I; Caramuta S; Ozata DM; Xie H; Lindforss U; Olivecrona H; Lui W-O
Article: PLOS ONE. 2011;6(3):e14757

Molecular characterization of acquired tolerance of tumor cells to picropodophyllin (PPP).

Hashemi J; Worrall C; Vasilcanu D; Fryknäs M; Sulaiman L; Karimi M; Weng W-H; Lui W-O; Rudduck C; Axelson M; Jernberg-Wiklund H; Girnita L; Larsson O; Larsson C
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2010;130(8):2062-2070

MicroRNA expression profiles associated with mutational status and survival in malignant melanoma.

Caramuta S; Egyházi S; Rodolfo M; Witten D; Hansson J; Larsson C; Lui W-O
Article: BMC BIOLOGY. 2010;8:58

Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls.

Witten D; Tibshirani R; Gu SG; Fire A; Lui W-O
Article: JOURNAL OF MOLECULAR DIAGNOSTICS. 2009;11(5):420-429

Profiling and discovery of novel miRNAs from formalin-fixed, paraffin-embedded melanoma and nodal specimens.

Ma Z; Lui W-O; Fire A; Dadras SS
Article: CANCER RESEARCH. 2008;68(17):7156-7164

CREB3L2-PPARgamma fusion mutation identifies a thyroid signaling pathway regulated by intramembrane proteolysis.

Lui W-O; Zeng L; Rehrmann V; Deshpande S; Tretiakova M; Kaplan EL; Leibiger I; Leibiger B; Enberg U; Höög A; Larsson C; Kroll TG
Article: ONCOGENE. 2008;27(14):2015-2026

MicroRNA expression signature of human sarcomas.

Subramanian S; Lui WO; Lee CH; Espinosa I; Nielsen TO; Heinrich MC; Corless CL; Fire AZ; van de Rijn M
Article: CANCER RESEARCH. 2007;67(13):6031-6043

Patterns of known and novel small RNAs in human cervical cancer.

Lui W-O; Pourmand N; Patterson BK; Fire A
Article: ENDOCRINE-RELATED CANCER. 2007;14(2):381-391

A PCR-based expression signature of malignancy in follicular thyroid tumors.

Foukakis T; Gusnanto A; Au AYM; Höög A; Lui W-O; Larsson C; Wallin G; Zedenius J
Article: THYROID. 2007;17(4):289-301

Molecular cytogenetic profiles of novel and established human anaplastic thyroid carcinoma models.

Lee J-J; Foukakis T; Hashemi J; Grimelius L; Heldin N-E; Wallin G; Rudduck C; Lui W-O; Höög A; Larsson C
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2006;29(5):1173-1182

A dog pedigree with familial medullary thyroid cancer.

Lee J-J; Larsson C; Lui W-O; Höög A; Von Euler H
Article: ONCOGENE. 2006;25(22):3186-3195

The insulin-like growth factor-1 receptor inhibitor PPP produces only very limited resistance in tumor cells exposed to long-term selection.

Vasilcanu D; Weng W-H; Girnita A; Lui W-O; Vasilcanu R; Axelson M; Larsson O; Larsson C; Girnita L
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2006;91(3):1143-1149

The Ras effector NORE1A is suppressed in follicular thyroid carcinomas with a PAX8-PPARgamma fusion.

Foukakis T; Au AYM; Wallin G; Geli J; Forsberg L; Clifton-Bligh R; Robinson BG; Lui W-O; Zedenius J; Larsson C
Article: CLINICAL CANCER RESEARCH. 2005;11(17):6198-6204

Prognostic impact of immunohistochemical expression of ezrin in highly malignant soft tissue sarcomas.

Weng W-H; Ahlén J; Aström K; Lui W-O; Larsson C
Article: ONCOGENE. 2005;24(8):1467-1476

Expression profiling reveals a distinct transcription signature in follicular thyroid carcinomas with a PAX8-PPAR(gamma) fusion oncogene.

Lui W-O; Foukakis T; Lidén J; Thoppe SR; Dwight T; Höög A; Zedenius J; Wallin G; Reimers M; Larsson C
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2005;26(1):141-149

Molecular cytogenetic characterization of primary cultures and established cell lines from non-medullary thyroid tumors.

Foukakis T; Thoppe SR; Lagercrantz S; Dwight T; Weng W-H; Svensson A; Höög A; Zedenius J; Wallin G; Lui W-O; Larsson C
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2005;26(1):5-16

Loss of chromosome 13q is a frequently acquired event in genetic progression of soft tissue sarcomas in the abdominal cavity.

Weng W-H; Lerner M; Grandér D; Ahlén J; Villablanca A; Pang S-T; Wejde J; Lui W-O; Larsson C
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2004;24(6):1419-1425

Histone deacetylase inhibitor 4-phenylbutyrate suppresses GAPDH mRNA expression in glioma cells.

Appelskog IB; Ammerpohl O; Svechnikova IG; Lui W-O; Almqvist PM; Ekström TJ
Article: CANCER GENETICS. 2004;150(1):27-32

Characterization of large chromosome markers in a malignant fibrous histiocytoma by spectral karyotyping, comparative genomic hybridization (CGH), and array CGH.

Weng W-H; Wejde J; Ahlén J; Pang S-T; Lui W-O; Larsson C
Article: CYTOGENETIC AND GENOME RESEARCH. 2004;106(1):28-32

Analysis of the cytogenetic stability of the human embryonal kidney cell line 293 by cytogenetic and STR profiling approaches.

Bylund L; Kytölä S; Lui W-O; Larsson C; Weber G
Article: CANCER CELL. 2003;4(5):405-413

The t(1;3) breakpoint-spanning genes LSAMP and NORE1 are involved in clear cell renal cell carcinomas.

Chen J; Lui W-O; Vos MD; Clark GJ; Takahashi M; Schoumans J; Khoo SK; Petillo D; Lavery T; Sugimura J; Astuti D; Zhang C; Kagawa S; Maher ER; Larsson C; Alberts AS; Kanayama H-O; Teh BT
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2003;88(9):4440-4445

Involvement of the PAX8/peroxisome proliferator-activated receptor gamma rearrangement in follicular thyroid tumors.

Dwight T; Thoppe SR; Foukakis T; Lui WO; Wallin G; Höög A; Frisk T; Larsson C; Zedenius J
Article: BRITISH JOURNAL OF CANCER. 2003;89(4):720-726

Gain of 17q in malignant fibrous histiocytoma is associated with a longer disease-free survival and a low risk of developing distant metastasis.

Weng W-H; Ahlén J; Lui W-O; Brosjö O; Pang S-T; Von Rosen A; Auer G; Larsson O; Larsson C
Article: CANCER GENETICS. 2003;141(1):43-48

Molecular cytogenetic characterization of four commonly used cell lines derived from Hodgkin lymphoma.

Berglund M; Flordal E; Gullander J; Lui W-O; Larsson C; Lagercrantz S; Enblad G
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2002;21(6):1197-1204

Identifying cancer-related genes in nasopharyngeal carcinoma cell lines using DNA and mRNA expression profiling analyses.

Guo X; Lui W-O; Qian C-N; Chen J-D; Gray SG; Rhodes D; Haab B; Stanbridge E; Wang H; Hong M-H; Min H-Q; Larsson C; Teh BT
Article: ENDOCRINOLOGIST. 2002;12(6):491-496

A pair of monozygotic twins with Klinefelters syndrome and early onset diabetes mellitus: A clinical and cytogenetic study

Tan MH; Lui WO; Rajasoorya C
Article: MODERN PATHOLOGY. 2002;15(8):807-816

Chromosomal imbalances in diffuse large B-cell lymphoma detected by comparative genomic hybridization.

Berglund M; Enblad G; Flordal E; Lui W-O; Backlin C; Thunberg U; Sundström C; Roos G; Allander SV; Erlanson M; Rosenquist R; Larsson C; Lagercrantz S
Article: ONCOGENE. 2002;21(26):4181-4190

Co-existence of SYT-SSX1 and SYT-SSX2 fusions in synovial sarcomas.

Yang K; Lui W-O; Xie Y; Zhang A; Skytting B; Mandahl N; Larsson C; Larsson O
Article: ONCOGENE. 2002;21(7):1117-1122

Selective loss of chromosome 11 in pheochromocytomas associated with the VHL syndrome.

Lui WO; Chen J; Gläsker S; Bender BU; Madura C; Khoo SK; Kort E; Larsson C; Neumann HPH; Teh BT
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2001;19(3):451-457

High level amplification of 1p32-33 and 2p22-24 in small cell lung carcinomas.

Lui WO; Tanenbaum DM; Larsson C
Article: INTERNATIONAL JOURNAL OF CANCER. 2001;92(6):824-831

Characterization of chromosomal abnormalities in uroepithelial carcinomas by G-banding, spectral karyotyping and FISH analysis.

Fadl-Elmula I; Kytölä S; Pan Y; Lui WO; Derienzo G; Forsberg L; Mandahl N; Gorunova L; Bergerheim US; Heim S; Larsson C
Article: CANCER GENETICS. 2001;127(2):128-133

A highly aggressive primitive mesenchymal tumor with a translocation (1;19)(q12;q13.2).

Lui W; Wejde J; Tani E; Brosjö O; Kytölä S; Larsson C
Article: JOURNAL OF MEDICAL GENETICS. 2001;38(3):165-170

Association of a novel constitutional translocation t(1q;3q) with familial renal cell carcinoma.

Kanayama H; Lui WO; Takahashi M; Naroda T; Kedra D; Wong FK; Kuroki Y; Nakahori Y; Larsson C; Kagawa S; Teh BT
Article: GENES CHROMOSOMES & CANCER. 2001;30(2):187-195

5q11, 8p11, and 10q22 are recurrent chromosomal breakpoints in prostate cancer cell lines.

Pan Y; Lui WO; Nupponen N; Larsson C; Isola J; Visakorpi T; Bergerheim US; Kytölä S
Article: NATURE BIOTECHNOLOGY. 2000;18(9):1001-1005

Loss-of-heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays.

Lindblad-Toh K; Tanenbaum DM; Daly MJ; Winchester E; Lui WO; Villapakkam A; Stanton SE; Larsson C; Hudson TJ; Johnson BE; Lander ES; Meyerson M
Article: CANCER GENETICS. 2000;121(1):61-66

Cytogenetic analysis of invasive breast cancer: a study of 27 Asian patients.

Tan PH; Lui WO; Ong P; Lau LC; Tao M; Chong Y
Article: CANCER GENETICS. 2000;119(2):109-112

Balanced translocation (3;7)(p25;q34): another mechanism of tumorigenesis in follicular thyroid carcinoma?

Lui WO; Kytölä S; Anfalk L; Larsson C; Farnebo LO
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2000;5(1):33-41

Modulating IGFBP-3 expression by trichostatin A: potential therapeutic role in the treatment of hepatocellular carcinoma.

Gray SG; Kytola S; Lui WO; Larsson C; Ekstrom TJ
Article: CYTOGENETIC AND GENOME RESEARCH. 1999;87(3-4):225-232

Characterization of chromosomal abnormalities in prostate cancer cell lines by spectral karyotyping.

Pan Y; Kytölä S; Farnebo F; Wang N; Lui WO; Nupponen N; Isola J; Visakorpi T; Bergerheim US; Larsson C
Article: CANCER GENETICS. 1998;105(1):69-73

Acute promyelocytic leukemia with a dicentric chromosome involving chromosomes 11, 17, and 18.

Chong YY; Wong GC; Lau LC; Knight L; Lim P; Lui WO; Yong MH; Goh YT; Tan P
Article: CANCER GENETICS. 1998;103(1):65-67

A case of t(8;14) with total and partial trisomy 3 in Waldenstrom macroglobulinemia.

Chong YY; Lau LC; Lui WO; Lim P; Lim E; Tan PH; Tan P; Ong YY
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All other publications

Editorial comment: CANCERS. 2021;13(9):2259

New Insights into the Biological and Clinical Aspects of Merkel Cell Carcinoma.

Koljonen V; Lui W-O; Becker JC
Letter: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2012;10(10):2202-2205

Thrombin induces de novo protein synthesis of stromal cell-derived factor-1α but not angiostatin in human platelets.

Huang Z; Rahman MF-U; Jiang L; Xie H; Hu H; Lui W-O; Li N
Meeting abstract: EUROPEAN JOURNAL OF CANCER, SUPPLEMENT. 2010;8(5):187

Altered expression of miR-205 affects cell proliferation in human cervical cancer

Xie H; Caramuta S; Larsson C; Lui WO
Meeting abstract: EUROPEAN JOURNAL OF CANCER, SUPPLEMENT. 2010;8(5):185

Role of microRNAs and microRNA machinery in the pathogenesis of diffuse large B-cell lymphomas

Caramuta S; Berglund M; Ozata D; Akcakaya P; Georgii-Hemming P; Xie H; Enblad G; Larsson C; Lui WO
Meeting abstract: EUROPEAN JOURNAL OF CANCER, SUPPLEMENT. 2010;8(5):224

The involvement of miR-483 and its host gene IGF2 in development of adrenal cortical carcinoma

Ozata D; Caramuta S; Akcakaya P; Xie HONG; Backdahl M; Larsson C; Lui W
Letter: CANCER GENETICS. 2002;136(2):153-154

Myelodysplastic syndrome with transformation to AML-M7 in a 46,XX male patient.

Lau L-C; Lim P; Lee L-H; Hwang W; Lui W-O; Chong Y-Y

Employments

Senior Lecturer, Department of Oncology-Pathology, Karolinska Institutet, 2016-

Degrees and Education

Docent, Karolinska Institutet, 2014
Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2002

Supervisor

Hannah Björn Andtback, 2022
Yaije Yang, 2021

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