Tiina Skoog

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Articles

Article: STAR PROTOCOLS. 2023;4(3):102357

Optimized single-cell RNA sequencing protocol to study early genome activation in mammalian preimplantation development.

Boskovic N; Yazgeldi G; Ezer S; Tervaniemi MH; Inzunza J; Deligiannis SP; Yaşar B; Skoog T; Krjutškov K; Katayama S; Kere J
Article: NATURE COMMUNICATIONS. 2022;13(1):3798

Biomarkers of nanomaterials hazard from multi-layer data.

Fortino V; Kinaret PAS; Fratello M; Serra A; Saarimäki LA; Gallud A; Gupta G; Vales G; Correia M; Rasool O; Ytterberg J; Monopoli M; Skoog T; Ritchie P; Moya S; Vázquez-Campos S; Handy R; Grafström R; Tran L; Zubarev R; Lahesmaa R; Dawson K; Loeschner K; Larsen EH; Krombach F; Norppa H; Kere J; Savolainen K; Alenius H; Fadeel B; Greco D
Article: JOURNAL OF DERMATOLOGICAL SCIENCE. 2022;106(3):132-140

Influence of FLG loss-of-function mutations in host-microbe interactions during atopic skin inflammation.

Oláh P; Szlávicz E; Kuchner M; Nemmer J; Zeeuwen P; Lefèvre-Utile A; Fyhrquist N; Prast-Nielsen S; Skoog T; Serra A; Rodríguez E; Raap U; Meller S; Gyulai R; Hupé P; Kere J; Levi-Schaffer F; Tsoka S; Alexander H; Nestle FO; Schröder JM; Weidinger S; van den Bogaard E; Soumelis V; Greco D; Barker J; Lauerma A; Ranki A; Andersson B; Alenius H; Homey B
Article: JOURNAL OF INTERNAL MEDICINE. 2021;290(2):404-415

Founder effects facilitate the use of a genotyping-based approach to molecular diagnosis in Swedish patients with familial hypercholesterolaemia.

Benedek P; Jiao H; Duvefelt K; Skoog T; Linde M; Kiviluoma P; Kere J; Eriksson M; Angelin B
Article: ADVANCED SCIENCE. 2021;8(10):2004588

Toxicogenomic Profiling of 28 Nanomaterials in Mouse Airways.

Kinaret PAS; Ndika J; Ilves M; Wolff H; Vales G; Norppa H; Savolainen K; Skoog T; Kere J; Moya S; Handy RD; Karisola P; Fadeel B; Greco D; Alenius H
Article: ADVANCED SCIENCE. 2020;7(22):2002221

Multiparametric Profiling of Engineered Nanomaterials: Unmasking the Surface Coating Effect.

Gallud A; Delaval M; Kinaret P; Marwah VS; Fortino V; Ytterberg J; Zubarev R; Skoog T; Kere J; Correia M; Loeschner K; Al-Ahmady Z; Kostarelos K; Ruiz J; Astruc D; Monopoli M; Handy R; Moya S; Savolainen K; Alenius H; Greco D; Fadeel B
Article: EBIOMEDICINE. 2020;59:102872

Fetal HLA-G mediated immune tolerance and interferon response in preeclampsia.

Wedenoja S; Yoshihara M; Teder H; Sariola H; Gissler M; Katayama S; Wedenoja J; Häkkinen IM; Ezer S; Linder N; Lundin J; Skoog T; Sahlin E; Iwarsson E; Pettersson K; Kajantie E; Mokkonen M; Heinonen S; Laivuori H; Krjutškov K; Kere J
Article: NATURE COMMUNICATIONS. 2019;10(1):4703

Microbe-host interplay in atopic dermatitis and psoriasis.

Fyhrquist N; Muirhead G; Prast-Nielsen S; Jeanmougin M; Olah P; Skoog T; Jules-Clement G; Feld M; Barrientos-Somarribas M; Sinkko H; van den Bogaard EH; Zeeuwen PLJM; Rikken G; Schalkwijk J; Niehues H; Däubener W; Eller SK; Alexander H; Pennino D; Suomela S; Tessas I; Lybeck E; Baran AM; Darban H; Gangwar RS; Gerstel U; Jahn K; Karisola P; Yan L; Hansmann B; Katayama S; Meller S; Bylesjö M; Hupé P; Levi-Schaffer F; Greco D; Ranki A; Schröder JM; Barker J; Kere J; Tsoka S; Lauerma A; Soumelis V; Nestle FO; Homey B; Andersson B; Alenius H
Article: SCIENTIFIC REPORTS. 2019;9(1):13758

The human long non-coding RNA gene RMRP has pleiotropic effects and regulates cell-cycle progression at G2.

Vakkilainen S; Skoog T; Einarsdottir E; Middleton A; Pekkinen M; Öhman T; Katayama S; Krjutškov K; Kovanen PE; Varjosalo M; Lindqvist A; Kere J; Mäkitie O
Article: BMC BIOINFORMATICS. 2019;20(1):418

Guide for library design and bias correction for large-scale transcriptome studies using highly multiplexed RNAseq methods.

Katayama S; Skoog T; Söderhäll C; Einarsdottir E; Krjutškov K; Kere J
Article: SCIENTIFIC REPORTS. 2019;9(1):4366

Cationic gold nanoparticles elicit mitochondrial dysfunction: a multi-omics study.

Gallud A; Klöditz K; Ytterberg J; Östberg N; Katayama S; Skoog T; Gogvadze V; Chen Y-Z; Xue D; Moya S; Ruiz J; Astruc D; Zubarev R; Kere J; Fadeel B
Article: BMC GENOMICS. 2018;19(1):432

Intracellular signalling pathways and cytoskeletal functions converge on the psoriasis candidate gene CCHCR1 expressed at P-bodies and centrosomes.

Tervaniemi MH; Katayama S; Skoog T; Siitonen HA; Vuola J; Nuutila K; Tammimies K; Suomela S; Kankuri E; Kere J; Elomaa O
Article: SCIENTIFIC REPORTS. 2017;7:45771

Sequence analysis of pooled bacterial samples enables identification of strain variation in group A streptococcus.

Weldatsadik RG; Wang J; Puhakainen K; Jiao H; Jalava J; Räisänen K; Datta N; Skoog T; Vuopio J; Jokiranta TS; Kere J
Article: SCIENTIFIC REPORTS. 2016;6:33256

Investigation of rare and low-frequency variants using high-throughput sequencing with pooled DNA samples.

Wang J; Skoog T; Einarsdottir E; Kaartokallio T; Laivuori H; Grauers A; Gerdhem P; Hytönen M; Lohi H; Kere J; Jiao H
Article: SCIENTIFIC REPORTS. 2016;6:22745

NOD-like receptor signaling and inflammasome-related pathways are highlighted in psoriatic epidermis.

Tervaniemi MH; Katayama S; Skoog T; Siitonen HA; Vuola J; Nuutila K; Sormunen R; Johnsson A; Linnarsson S; Suomela S; Kankuri E; Kere J; Elomaa O
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2015;171(4):478-490

Aberrant splicing of genes involved in haemoglobin synthesis and impaired terminal erythroid maturation in SF3B1 mutated refractory anaemia with ring sideroblasts.

Conte S; Katayama S; Vesterlund L; Karimi M; Dimitriou M; Jansson M; Mortera-Blanco T; Unneberg P; Papaemmanuil E; Sander B; Skoog T; Campbell P; Walfridsson J; Kere J; Hellström-Lindberg E
Article: BMC GENOMICS. 2015;16(1):476

Gene expression analysis of skin grafts and cultured keratinocytes using synthetic RNA normalization reveals insights into differentiation and growth control.

Katayama S; Skoog T; Jouhilahti E-M; Siitonen HA; Nuutila K; Tervaniemi MH; Vuola J; Johnsson A; Lönnerberg P; Linnarsson S; Elomaa O; Kankuri E; Kere J
Article: PLOS ONE. 2009;4(12):e8037

Identification of MAMDC1 as a candidate susceptibility gene for systemic lupus erythematosus (SLE).

Hellquist A; Zucchelli M; Lindgren CM; Saarialho-Kere U; Järvinen TM; Koskenmies S; Julkunen H; Onkamo P; Skoog T; Panelius J; Räisänen-Sokolowski A; Hasan T; Widen E; Gunnarson I; Svenungsson E; Padyukov L; Assadi G; Berglind L; Mäkelä V-V; Kivinen K; Wong A; Cunningham Graham DS; Vyse TJ; D'Amato M; Kere J
Article: VIRCHOWS ARCHIV. 2009;455(6):495-503

Expression of MMP-10, MMP-21, MMP-26, and MMP-28 in Merkel cell carcinoma.

Suomela S; Koljonen V; Skoog T; Kukko H; Böhling T; Saarialho-Kere U
Article: EXPERIMENTAL DERMATOLOGY. 2009;18(12):1044-1052

MMP-10 (Stromelysin-2) and MMP-21 in human and murine squamous cell cancer.

Boyd S; Virolainen S; Pärssinen J; Skoog T; van Hogerlinden M; Latonen L; Kyllönen L; Toftgard R; Saarialho-Kere U
Article: PLOS ONE. 2009;4(6):e6030

CCHCR1 is up-regulated in skin cancer and associated with EGFR expression.

Suomela S; Elomaa O; Skoog T; Ala-aho R; Jeskanen L; Pärssinen J; Latonen L; Grénman R; Kere J; Kähäri V-M; Saarialho-Kere U
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2009;129(1):119-130

Matrix metalloproteinase-21 expression is associated with keratinocyte differentiation and upregulated by retinoic acid in HaCaT cells.

Skoog T; Elomaa O; Pasonen-Seppänen SM; Forsberg S; Ahokas K; Jeskanen L; Pärssinen J; Tiala I; Rollman O; Lohi J; Saarialho-Kere U
Article: MODERN PATHOLOGY. 2007;20(11):1128-1140

Increased expression of matrix metalloproteinases-21 and -26 and TIMP-4 in pancreatic adenocarcinoma.

Bister V; Skoog T; Virolainen S; Kiviluoto T; Puolakkainen P; Saarialho-Kere U
Article: JOURNAL OF MEDICAL GENETICS. 2007;44(5):314-321

The human GIMAP5 gene has a common polyadenylation polymorphism increasing risk to systemic lupus erythematosus.

Hellquist A; Zucchelli M; Kivinen K; Saarialho-Kere U; Koskenmies S; Widen E; Julkunen H; Wong A; Karjalainen-Lindsberg M-L; Skoog T; Vendelin J; Cunninghame-Graham DS; Vyse TJ; Kere J; Lindgren CM
Article: ACTA DERMATO-VENEREOLOGICA. 2007;87(3):223-227

Expression of allograft inflammatory factor-1 in inflammatory skin disorders.

Orsmark C; Skoog T; Jeskanen L; Kere J; Saarialho-Kere U
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;351(3):777-783

Allele-specific chromatin remodeling of the tumor necrosis factor-alpha promoter.

Skoog T; Hamsten A; Eriksson P
Article: EXPERIMENTAL DERMATOLOGY. 2006;15(10):775-783

MMP-21 is expressed by macrophages and fibroblasts in vivo and in culture.

Skoog T; Ahokas K; Orsmark C; Jeskanen L; Isaka K; Saarialho-Kere U
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2005;124(4):849-856

Matrilysin-2 (matrix metalloproteinase-26) is upregulated in keratinocytes during wound repair and early skin carcinogenesis.

Ahokas K; Skoog T; Suomela S; Jeskanen L; Impola U; Isaka K; Saarialho-Kere U
Article: EUROPEAN HEART JOURNAL. 2002;23(5):376-383

Plasma tumour necrosis factor-alpha and early carotid atherosclerosis in healthy middle-aged men.

Skoog T; Dichtl W; Boquist S; Skoglund-Andersson C; Karpe F; Tang R; Bond MG; de Faire U; Nilsson J; Eriksson P; Hamsten A
Article: HUMAN MOLECULAR GENETICS. 1999;8(8):1443-1449

A common functional polymorphism (C-->A substitution at position -863) in the promoter region of the tumour necrosis factor-alpha (TNF-alpha) gene associated with reduced circulating levels of TNF-alpha.

Skoog T; van't Hooft FM; Kallin B; Jovinge S; Boquist S; Nilsson J; Eriksson P; Hamsten A
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Preprint: RESEARCH SQUARE. 2022

Biomarkers of nanomaterials hazard from multi-layer data

Fortino V; Kinaret P; Fratello M; Serra A; Saarimäki L; Gallud A; Gupta G; Vales G; Correia M; Rasool O; Ytterberg J; Monopoli M; Skoog T; Ritchie P; Moya S; Vázquez-Campos S; Handy R; Grafström R; Tran L; Zubarev R; Lahesmaa R; Dawson K; Löschner K; Larsen E; Krombach F; Norppa H; Kere J; Savolainen K; Alenius H; Fadeel B; Greco D
Preprint: BIORXIV. 2019

Balancing Selection atHLA-GModulates Fetal Survival, Preeclampsia and Human Birth Sex Ratio

Wedenoja S; Yoshihara M; Teder H; Sariola H; Gissler M; Katayama S; Wedenoja J; Häkkinen IM; Ezer S; Linder N; Lundin J; Skoog T; Sahlin E; Iwarsson E; Pettersson K; Kajantie E; Mokkonen M; Heinonen S; Laivuori H; Krjutškov K; Kere J
Letter: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2019;139(9):2058-2061.e4

Delineating the Healthy Human Skin UV Response and Early Induction of Interferon Pathway in Cutaneous Lupus Erythematosus.

Katayama S; Panelius J; Koskenmies S; Skoog T; Mähönen K; Kisand K; Bondet V; Duffy D; Krjutškov K; Kere J; Ranki A
Letter: DIABETOLOGIA. 2001;44(5):654-655

Tumour necrosis factor-alpha (TNF-alpha) polymorphisms-857C/A and -863C/A are associated with TNF-alpha secretion from human adipose tissue.

Skoog T; Eriksson P; Hoffstedt J; Rydén M; Hamsten A; Armer P
Meeting abstract: ATHEROSCLEROSIS. 1999;144:121

A common polymorphism in the promoter region of TNF-alpha gene determining the serum TNF-alpha concentration

Skoog T; van't Hooft FM; Kallin B; Nilsson J; Eriksson P; Hamsten A

Employments

Research Engineer, Department of Medicine, Huddinge, Karolinska Institutet, 2024-
Research Engineer, Department of Biosciences and Nutrition, Karolinska Institutet, 2009-2024

Degrees and Education

Doctor Of Philosophy, Department of Medicine, Solna, Karolinska Institutet, 2003

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