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About me

Present: Assistant Member at Ludwig Institute for Cancer Research

2006-2008: Instructor of Medicine, Dana-Farber Cancer Institute/Harvard Medical School, Boston, USA

2003-2006: Postdoctoral Fellow, Dana-Farber Cancer Institute/Harvard Medical School, Boston, USA



2002: PhD, Duke University Medical School, Durham, N.C., USA, 2002

1999: MSc, Humboldt University, Berlin, Germany

Research description

Our research concerns the mechanisms of how disruption of oxygen-sensing pathways can lead to cancer. Oxygen sensors enable the cell to adapt to low-oxygen environments and are critical for normal development and apoptosis. These events are often disrupted in the development of tumors. Oxygen sensing is mediated partly via prolyl hydroxylases that require molecular oxygen for enzymatic activity. Our work focuses on how prolyl hydroxylases execute apoptosis in neural precursors during development and how disruption of this process can lead to certain forms of nervous-system tumors.

Academic honors, awards and prizes

Friends for Life Dana-Farber Award, Boston, USA, March 2008

Melanoma Research Award MRF, USA, January 2008

Friends of Dana-Farber Award, Boston, USA, October 2007

Charles H. Hood Child Health Research Award, USA, June 2007

VHL Family Alliance Research Award, USA, June 2006

Charles A. King Trust Postdoctoral Research Fellowship, USA, June 2006

Keystone Symposia Scholarship, Hypoxia and Development, Physiology and Disease (A5), USA, January 2006

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2015   Invited Speaker, Network for Neuroblastoma and CNS-tumor Research in Children, Swedish Childhood Cancer Foundation Conference, Gothenburg, Sweden  

2015 Invited Speaker, Wenner-Gren Institute, Stockholm University, Sweden

2014   Invited Speaker, Cancer Symposium organized by Karolinska Institute, Cancer Science Institute of Singapore and National University of Singapore, Nobel Forum, Stockholm, Sweden.

2013 Invited Speaker, HypoxiaNet conference Oxygen2013, Oulu, Finland

2013 Invited Speaker, Ludwig Cancer Research symposium, Eynsham Hall, Oxford UK

2012 Invited Speaker, Symposium: Childhood Cancer Research- -from biology to cure and beyond, Stockholm, Sweden

2012 Invited Speaker, University of Turku, Finland,

2012 Invited Speaker and chair, ISAM The 10th World Congress of the International Society for Adaptive Medicine, Bucharest, Romania

2010 Invited Speaker, University of Oulu, Finland

2010 Invited Speaker, Stockholm University, Wenner-Gren Institute, Sweden

2010 Invited Speaker, LICR drug development meeting, NYC, USA

2009 Invited Speaker, LICR branch meeting, Oxford, UK

2008 Invited Speaker, Scripps Institute, Jupiter, Florida, USA

2008 Invited Speaker, Harvard Public Health, Boston, MA, USA

2008 Invited Speaker, Beatson Cancer Institute, Glasgow, UK

2007 Invited Speaker: Keystone Symposia: Cancer Stem Cell, Short talk Colorado, USA

2007 Invited Speaker: Annual VHLFA Meeting, Boston MA

2007 Invited Speaker: Neuroblastoma Translational Research Group, Dana Farber Cancer Institute/ Harvard Medical School, Boston, MA, USA.

2006 Invited Speaker: WorldMEN 2006, Marseille, France

2006 Invited Speaker: Gordon conference: Cancer models and Mechanism, Short talk, Bryant University, Smithfield, USA