Sigrún Sif Thórsdóttir

Publications
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Articles

Article: MBIO. 2022;13(5):e0188622-e01822

Dysfunctional Glymphatic System with Disrupted Aquaporin 4 Expression Pattern on Astrocytes Causes Bacterial Product Accumulation in the CSF during Pneumococcal Meningitis.

Generoso JS; Thorsdottir S; Collodel A; Dominguini D; Santo RRE; Petronilho F; Barichello T; Iovino F
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2022;119(23):e2122386119

Membrane particles evoke a serotype-independent cross-protection against pneumococcal infection that is dependent on the conserved lipoproteins MalX and PrsA.

Narciso AR; Iovino F; Thorsdottir S; Mellroth P; Codemo M; Spoerry C; Righetti F; Muschiol S; Normark S; Nannapaneni P; Henriques-Normark B
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:904415

A comparative study of adjuvants effects on neonatal plasma cell survival niche in bone marrow and persistence of humoral immune responses.

Aradottir Pind AA; Thorsdottir S; Magnusdottir GJ; Meinke A; Del Giudice G; Jonsdottir I; Bjarnarson SP
Article: PLOS PATHOGENS. 2021;17(3):e1009432

Neuronal death in pneumococcal meningitis is triggered by pneumolysin and RrgA interactions with β-actin.

Tabusi M; Thorsdottir S; Lysandrou M; Narciso AR; Minoia M; Srambickal CV; Widengren J; Henriques-Normark B; Iovino F
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:2214

Adjuvants Enhance the Induction of Germinal Center and Antibody Secreting Cells in Spleen and Their Persistence in Bone Marrow of Neonatal Mice.

Aradottir Pind AA; Dubik M; Thorsdottir S; Meinke A; Harandi AM; Holmgren J; Del Giudice G; Jonsdottir I; Bjarnarson SP
Article: JOURNAL OF INFECTIOUS DISEASES. 2018;218(3):476-484

Receptor Blockade: A Novel Approach to Protect the Brain From Pneumococcal Invasion.

Iovino F; Thorsdottir S; Henriques-Normark B

All other publications

Thesis / dissertation: 2022

Mechanisms for pneumococcal meningitis and a new vaccine platform to raise a serotype-independent protection in the host

Thorsdottir, Sigrun
Review: FRONTIERS IN MICROBIOLOGY. 2019;10:576

The Role of Microglia in Bacterial Meningitis: Inflammatory Response, Experimental Models and New Neuroprotective Therapeutic Strategies.

Thorsdottir S; Henriques-Normark B; Iovino F

Employments

Postdoctoral Researcher, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2023-2025

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2022
Degree Of Master Of Medical Science 120 Credits, Karolinska Institutet, 2017
Degree Of Bachelor Of Medical Science, Karolinska Institutet, 2015

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