Sara Svensson Akusjärvi

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About me

Postdoctoral researcher in the Ivan Zanoni lab at Boston Children's Hospital, Harvard Medical School and Anna Smed Sörensen lab at Karolinska Institutet.

Research focus on the IFN response during respiratory infections.

Articles

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(37):e2304722120

Systems-level temporal immune-metabolic profile in Crimean-Congo hemorrhagic fever virus infection.

Ambikan AT; Elaldi N; Svensson-Akusjärvi S; Bagci B; Pektas AN; Hewson R; Bagci G; Arasli M; Appelberg S; Mardinoglu A; Sood V; Végvári Á; Benfeitas R; Gupta S; Cetin I; Mirazimi A; Neogi U
Article: AIDS. 2023;37(7):1023-1033

Role of myeloid cells in system-level immunometabolic dysregulation during prolonged successful HIV-1 treatment.

Svensson Akusjärvi S; Krishnan S; Ambikan AT; Mikaeloff F; Munusamy Ponnan S; Vesterbacka J; Lourda M; Nowak P; Sönnerborg A; Neogi U
Article: CURRENT HIV/AIDS REPORTS. 2023;20(2):42-50

Biological Aging in People Living with HIV on Successful Antiretroviral Therapy: Do They Age Faster?

Akusjärvi SS; Neogi U
Article: LIFE SCIENCE ALLIANCE. 2022;5(9):e202201405

Genome-scale metabolic models for natural and long-term drug-induced viral control in HIV infection.

Ambikan AT; Svensson-Akusjärvi S; Krishnan S; Sperk M; Nowak P; Vesterbacka J; Sönnerborg A; Benfeitas R; Neogi U
Article: CELL SYSTEMS. 2022;13(8):665-681.e4

Multi-omics personalized network analyses highlight progressive disruption of central metabolism associated with COVID-19 severity.

Ambikan AT; Yang H; Krishnan S; Svensson Akusjärvi S; Gupta S; Lourda M; Sperk M; Arif M; Zhang C; Nordqvist H; Ponnan SM; Sönnerborg A; Treutiger CJ; O'Mahony L; Mardinoglu A; Benfeitas R; Neogi U
Article: ELIFE. 2022;11:e76071

Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target.

Neogi U; Elaldi N; Appelberg S; Ambikan A; Kennedy E; Dowall S; Bagci BK; Gupta S; Rodriguez JE; Svensson-Akusjärvi S; Monteil V; Vegvari A; Benfeitas R; Banerjea A; Weber F; Hewson R; Mirazimi A
Article: COMMUNICATIONS BIOLOGY. 2022;5(1):357

Peripheral blood CD4+CCR6+ compartment differentiates HIV-1 infected or seropositive elite controllers from long-term successfully treated individuals.

Svensson Akusjärvi S; Krishnan S; Jütte BB; Ambikan AT; Gupta S; Rodriguez JE; Végvári Á; Sperk M; Nowak P; Vesterbacka J; Svensson JP; Sönnerborg A; Neogi U
Article: ISCIENCE. 2022;25(1):103607

Integrative proteo-transcriptomic and immunophenotyping signatures of HIV-1 elite control phenotype: A cross-talk between glycolysis and HIF signaling.

Akusjärvi SS; Ambikan AT; Krishnan S; Gupta S; Sperk M; Végvári Á; Mikaeloff F; Healy K; Vesterbacka J; Nowak P; Sönnerborg A; Neogi U
Article: COMMUNICATIONS BIOLOGY. 2022;5(1):27

Trans cohort metabolic reprogramming towards glutaminolysis in long-term successfully treated HIV-infection.

Mikaeloff F; Svensson Akusjärvi S; Ikomey GM; Krishnan S; Sperk M; Gupta S; Magdaleno GDV; Escós A; Lyonga E; Okomo MC; Tagne CT; Babu H; Lorson CL; Végvári Á; Banerjea AC; Kele J; Hanna LE; Singh K; de Magalhães JP; Benfeitas R; Neogi U
Article: AGING-US. 2021;13(19):22732-22751

The central role of the glutamate metabolism in long-term antiretroviral treated HIV-infected individuals with metabolic syndrome.

Gelpi M; Mikaeloff F; Knudsen AD; Benfeitas R; Krishnan S; Svenssson Akusjärvi S; Høgh J; Murray DD; Ullum H; Neogi U; Nielsen SD
Article: ISCIENCE. 2021;24(2):102111

Distinct lipid profile, low-level inflammation, and increased antioxidant defense signature in HIV-1 elite control status.

Sperk M; Mikaeloff F; Svensson-Akusjärvi S; Krishnan S; Ponnan SM; Ambikan AT; Nowak P; Sönnerborg A; Neogi U
Article: MOLECULAR & CELLULAR PROTEOMICS. 2021;20:100159

Metabolic Perturbation Associated With COVID-19 Disease Severity and SARS-CoV-2 Replication.

Krishnan S; Nordqvist H; Ambikan AT; Gupta S; Sperk M; Svensson-Akusjärvi S; Mikaeloff F; Benfeitas R; Saccon E; Ponnan SM; Rodriguez JE; Nikouyan N; Odeh A; Ahlén G; Asghar M; Sällberg M; Vesterbacka J; Nowak P; Végvári Á; Sönnerborg A; Treutiger CJ; Neogi U
Article: EMERGING MICROBES & INFECTIONS. 2020;9(1):1748-1760

Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells.

Appelberg S; Gupta S; Svensson Akusjärvi S; Ambikan AT; Mikaeloff F; Saccon E; Végvári Á; Benfeitas R; Sperk M; Ståhlberg M; Krishnan S; Singh K; Penninger JM; Mirazimi A; Neogi U
Article: PLOS PATHOGENS. 2020;16(1):e1008264

Chromatin maturation of the HIV-1 provirus in primary resting CD4+ T cells.

Lindqvist B; Svensson Akusjärvi S; Sönnerborg A; Dimitriou M; Svensson JP
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:1965

Systemic Inflammation and the Increased Risk of Inflamm-Aging and Age-Associated Diseases in People Living With HIV on Long Term Suppressive Antiretroviral Therapy.

Babu H; Ambikan AT; Gabriel EE; Svensson Akusjärvi S; Palaniappan AN; Sundaraj V; Mupanni NR; Sperk M; Cheedarla N; Sridhar R; Tripathy SP; Nowak P; Hanna LE; Neogi U
Article: FRONTIERS IN MICROBIOLOGY. 2018;9:2358

Characterization of Inducible Transcription and Translation-Competent HIV-1 Using the RNAscope ISH Technology at a Single-Cell Resolution.

Zhang W; Svensson Akusjärvi S; Sönnerborg A; Neogi U
Article: FRONTIERS IN PHARMACOLOGY. 2017;8:433

Phenotypic Screening Identifies Synergistically Acting Natural Product Enhancing the Performance of Biomaterial Based Wound Healing.

Sivasubramanian S; Chandrasekar G; Svensson Akusjärvi S; Thangam R; Sathuvan M; Kumar RBS; Hussein H; Vincent S; Madhan B; Gunasekaran P; Kitambi SS

All other publications

KI thesis / dissertation: 2022

Immunometabolic reprogramming during suppressive HIV-1 infection

Svensson Akusjärvi, Sara
Review: DRUG DESIGN DEVELOPMENT AND THERAPY. 2017;11:1957-1967

Cell and small animal models for phenotypic drug discovery.

Szabo M; Svensson Akusjärvi S; Saxena A; Liu J; Chandrasekar G; Kitambi SS

Employments

Postdoctoral Researcher, Department of Medicine, Karolinska Institutet, 2023-2025

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Laboratory Medicine, Karolinska Institutet, 2022

About me

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Degrees and Education

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