Sarah Mc Carrick

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About me

I am a postdoctoral researcher in Toxicology at the unit of Metals and Health at the Institute of Environmental Medicine. I recieved my master degree in Toxicology from Karolinska Institutet in 2017 and my PhD degree in 2022 from Karolinska Institutet with the thesis title "Exploring toxicity and fate of metal-based particles in the lung : from mechanistic screening to lung deposition modelling". My research is focused on investigating and understanding mechanisms related to particle toxicity, primarily using in vitro models and bioinformatic approaches.

Articles

Article: ARCHIVES OF TOXICOLOGY. 2022;96(4):969-985

Modelled lung deposition and retention of welding fume particles in occupational scenarios: a comparison to doses used in vitro.

McCarrick S; Karlsson HL; Carlander U
Article: WELDING IN THE WORLD. 2021;65(12):2319-2337

New weldable 316L stainless flux-cored wires with reduced Cr(VI) fume emissions: part 1-health aspects of particle composition and release of metals

Westin EM; McCarrick S; Laundry-Mottiar L; Wei Z; Biesinger MC; Barker I; Wagner R; Persson K-A; Trydell K; Odnevall I; Karlsson HL; Hedberg YS
Article: WELDING IN THE WORLD. 2021;65(12):2339-2348

New weldable 316L stainless flux-cored wires with reduced Cr(VI) fume emissions: part 2-round robin creating fume emission data sheets

Westin EM; McCarrick S; Laundry-Mottiar L; Wei Z; Wagner R; Persson K-A; Trydell K; Odnevall I; Karlsson HL; Hedberg YS
Article: ARCHIVES OF TOXICOLOGY. 2021;95(9):2961-2975

Genotoxicity and inflammatory potential of stainless steel welding fume particles: an in vitro study on standard vs Cr(VI)-reduced flux-cored wires and the role of released metals.

McCarrick S; Romanovski V; Wei Z; Westin EM; Persson K-A; Trydell K; Wagner R; Odnevall I; Hedberg YS; Karlsson HL
Article: JOURNAL OF HAZARDOUS MATERIALS. 2021;413:125273

Welding fume nanoparticles from solid and flux-cored wires: Solubility, toxicity, and role of fluorides.

Hedberg YS; Wei Z; McCarrick S; Romanovski V; Theodore J; Westin EM; Wagner R; Persson K-A; Karlsson HL; Odnevall Wallinder I
Article: CHEMICAL RESEARCH IN TOXICOLOGY. 2021;34(6):1481-1495

Adsorption of Horseradish Peroxidase on Metallic Nanoparticles: Effects on Reactive Oxygen Species Detection Using 2',7'-Dichlorofluorescin Diacetate.

Kessler A; Hedberg J; McCarrick S; Karlsson HL; Blomberg E; Odnevall I
Article: INTERNATIONAL JOURNAL OF NANOMEDICINE. 2021;16:5895-5908

Gold Nanoparticles Dissolve Extracellularly in the Presence of Human Macrophages.

McCarrick S; Midander K; Krausová M; Carlander U; Karlsson HL
Article: NANOMATERIALS. 2020;10(1):E110-110

ToxTracker Reporter Cell Lines as a Tool for Mechanism-Based (geno)Toxicity Screening of Nanoparticles-Metals, Oxides and Quantum Dots.

McCarrick S; Cappellini F; Kessler A; Moelijker N; Derr R; Hedberg J; Wold S; Blomberg E; Odnevall Wallinder I; Hendriks G; Karlsson HL
Article: NANOTOXICOLOGY. 2019;13(10):1293-1309

High variability in toxicity of welding fume nanoparticles from stainless steel in lung cells and reporter cell lines: the role of particle reactivity and solubility.

McCarrick S; Wei Z; Moelijker N; Derr R; Persson K-A; Hendriks G; Odnevall Wallinder I; Hedberg Y; Karlsson HL
Article: NANOTOXICOLOGY. 2019;13(8):1060-1072

Inflammation and (secondary) genotoxicity of Ni and NiO nanoparticles.

Åkerlund E; Islam MS; McCarrick S; Alfaro-Moreno E; Karlsson HL
Article: ENVIRONMENTAL POLLUTION. 2019;246:678-687

In vitro and in vivo genotoxicity of oxygenated polycyclic aromatic hydrocarbons.

McCarrick S; Cunha V; Zapletal O; Vondráček J; Dreij K
Article: BEHAVIOURAL BRAIN RESEARCH. 2019;359:927-934

Bold zebrafish (Danio rerio) express higher levels of delta opioid and dopamine D2 receptors in the brain compared to shy fish.

Thörnqvist P-O; McCarrick S; Ericsson M; Roman E; Winberg S
Article: NANOTOXICOLOGY. 2018;12(6):602-620

Mechanistic insight into reactivity and (geno)toxicity of well-characterized nanoparticles of cobalt metal and oxides.

Cappellini F; Hedberg Y; McCarrick S; Hedberg J; Derr R; Hendriks G; Odnevall Wallinder I; Karlsson HL

All other publications

KI thesis / dissertation: 2022

Exploring toxicity and fate of metal-based particles in the lung : from mechanistic screening to lung deposition modelling

McCarrick, Sarah

Employments

Postdoctoral Researcher, Institute of Environmental Medicine, Karolinska Institutet, 2022-2025

Degrees and Education

Degree Of Doctor Of Philosophy, Institute of Environmental Medicine, Karolinska Institutet, 2022
Degree Of Master Of Medical Science 120 Credits, Karolinska Institutet, 2018

About me

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