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Per Hydbring

Assistant professor

Visiting address : Cancercenter Karolinska Z5:01, Karolinska Universitetssjukhuset Solna 171 76 Stockholm, Sweden
Postal address : Department of Oncology-Pathology (OnkPat), K7, Research Group Lewensohn, Rolf, Cancercenter Karolinska Z5:01, Karolinska Universitetssjukhuset Solna 171 76 Stockholm, Sweden
Delivery address : Cancercenter Karolinska Z5:01, Karolinska Universitetssjukhuset Solna 171 76 Stockholm, Sweden


Cell-Cycle-Targeting MicroRNAs as Therapeutic Tools against Refractory Cancers
Hydbring P, Wang Y, Fassl A, Li X, Matia V, Otto T, et al
Cancer cell 2017;31(4):576-590.e8

Nanoparticles for immune system targeting
Du J, Zhang Ys, Hobson D, Hydbring P
Drug discovery today 2017;():-

Interferon-γ-induced p27KIP1 binds to and targets MYC for proteasome-mediated degradation
Bahram F, Hydbring P, Tronnersjö S, Zakaria Sm, Frings O, Fahlén S, et al
Oncotarget 2016;7(3):2837-54

Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases
Hydbring P, Malumbres M, Sicinski P
Nature reviews. Molecular cell biology 2016;17(5):280-92

D-cyclins repress apoptosis in hematopoietic cells by controlling death receptor Fas and its ligand FasL
Choi Yj, Saez B, Anders L, Hydbring P, Stefano J, Bacon Na, et al
Developmental cell 2014;30(3):255-67

Clinical applications of microRNAs
Hydbring P, Badalian-very G
F1000Research 2013;2():136-

The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop
Menssen A, Hydbring P, Kapelle K, Vervoorts J, Diebold J, Luscher B, et al

The requirement for cyclin D function in tumor maintenance
Choi Yj, Li X, Hydbring P, Sanda T, Stefano J, Christie Al, et al
Cancer cell 2012;22(4):438-51

A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells
Anders L, Ke N, Hydbring P, Choi Yj, Widlund Hr, Chick Jm, et al
Cancer cell 2011;20(5):620-34

Cdk2: a key regulator of the senescence control function of Myc
Hydbring P, Larsson Lg
Aging 2010;2(4):244-50

Cdk2 suppresses cellular senescence induced by the c-myc oncogene
Campaner S, Doni M, Hydbring P, Verrecchia A, Bianchi L, Sardella D, et al
NATURE CELL BIOLOGY 2010;12(1):54-9

Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation
Hydbring P, Bahram F, Su Y, Tronnersjö S, Högstrand K, Von Der Lehr N, et al
Proceedings of the National Academy of Sciences of the United States of America 2010;107(1):58-63

Tipping the balance: Cdk2 enables Myc to suppress senescence
Hydbring P, Larsson Lg
Cancer research 2010;70(17):6687-91

TGF-beta enforces senescence in Myc-transformed hematopoietic tumor cells through induction of Mad1 and repression of Myc activity
Wu S, Hultquist A, Hydbring P, Cetinkaya C, Oberg F, Larsson Lg
Experimental cell research 2009;315(18):3099-111

Direct observation of individual endogenous protein complexes in situ by proximity ligation
Söderberg O, Gullberg M, Jarvius M, Ridderstråle K, Leuchowius Kj, Jarvius J, et al
Nature methods 2006;3(12):995-1000

c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription
Arabi A, Wu S, Ridderstråle K, Bierhoff H, Shiue C, Fatyol K, et al
Nature cell biology 2005;7(3):303-10

The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription
Von Der Lehr N, Johansson S, Wu S, Bahram F, Castell A, Cetinkaya C, et al
Molecular cell 2003;11(5):1189-200

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