Per Antonson

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Articles

Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023;24(15):12461

Loss of ERβ in Aging LXRαβ Knockout Mice Leads to Colitis.

Song X; Wu W; Dai Y; Warner M; Nalvarte I; Antonson P; Varshney M; Gustafsson J-Å
Journal article: RECEPTORS. 2023;2(1):116-126

Estrogen Receptor Knockout Mice and Their Effects on Fertility

Nalvarte I; Antonson P
Article: CANCERS. 2023;15(4):1298

Sex- and Female Age-Dependent Differences in Gene Expression in Diffuse Large B-Cell Lymphoma-Possible Estrogen Effects.

Huang D; Berglund M; Damdimopoulos A; Antonson P; Lindskog C; Enblad G; Amini R-M; Okret S
Article: CELL DEATH & DISEASE. 2023;14(2):129

Harnessing the reverse cholesterol transport pathway to favor differentiation of monocyte-derived APCs and antitumor responses.

Raccosta L; Marinozzi M; Costantini S; Maggioni D; Ferreira LM; Corna G; Zordan P; Sorice A; Farinello D; Bianchessi S; Riba M; Lazarevic D; Provero P; Mack M; Bondanza A; Nalvarte I; Gustafsson J-A; Ranzani V; De Sanctis F; Ugel S; Baron S; Lobaccaro J-MA; Pontini L; Pacciarini M; Traversari C; Pagani M; Bronte V; Sitia G; Antonson P; Brendolan A; Budillon A; Russo V
Article: BIOMEDICINES. 2022;10(12):3100

Immunohistochemical Detection of Estrogen Receptor-Beta (ERβ) with PPZ0506 Antibody in Murine Tissue: From Pitfalls to Optimization.

Schröder SK; Tag CG; Kessel JC; Antonson P; Weiskirchen R
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2022;42(6):719-731

Myeloid LXR (Liver X Receptor) Deficiency Induces Inflammatory Gene Expression in Foamy Macrophages and Accelerates Atherosclerosis.

Endo-Umeda K; Kim E; Thomas DG; Liu W; Dou H; Yalcinkaya M; Abramowicz S; Xiao T; Antonson P; Gustafsson J-Å; Makishima M; Reilly MP; Wang N; Tall AR
Article: MOLECULAR PSYCHIATRY. 2021;26(11):6380-6393

Loss of liver X receptor β in astrocytes leads to anxiety-like behaviors via regulating synaptic transmission in the medial prefrontal cortex in mice.

Li X; Zhong H; Wang Z; Xiao R; Antonson P; Liu T; Wu C; Zou J; Wang L; Nalvarte I; Xu H; Warner M; Gustafsson J-A; Fan X
Article: MUCOSAL IMMUNOLOGY. 2021;14(2):411-419

Liver X receptor regulates Th17 and RORγt+ Treg cells by distinct mechanisms.

Parigi SM; Das S; Frede A; Cardoso RF; Tripathi KP; Doñas C; Hu YOO; Antonson P; Engstrand L; Gustafsson J-Å; Villablanca EJ
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2020;529(2):231-237

Generation of an all-exon Esr2 deleted mouse line: Effects on fertility.

Antonson P; Apolinário LM; Shamekh MM; Humire P; Poutanen M; Ohlsson C; Nalvarte I; Gustafsson J-Å
Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2020;198:105558

Lipidomic analysis of human primary hepatocytes following LXR activation with GW3965 identifies AGXT2L1 as a main target associated to changes in phosphatidylethanolamine.

Santinha D; Klopot A; Marques I; Ellis E; Jorns C; Johansson H; Melo T; Antonson P; Jakobsson T; Félix V; Gustafsson J-Å; Domingues MR; Mode A; Helguero LA
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(9):4902-4909

Ventral prostate and mammary gland phenotype in mice with complete deletion of the ERβ gene.

Warner M; Wu W-F; Montanholi L; Nalvarte I; Antonson P; Gustafsson J-A
Article: CELL REPORTS. 2018;25(13):3774-3785.e4

LXR Suppresses Inflammatory Gene Expression and Neutrophil Migration through cis-Repression and Cholesterol Efflux.

Thomas DG; Doran AC; Fotakis P; Westerterp M; Antonson P; Jiang H; Jiang X-C; Gustafsson J-Å; Tabas I; Tall AR
Article: NATURE COMMUNICATIONS. 2018;9(1):5457

Molecular and functional heterogeneity of IL-10-producing CD4+ T cells.

Brockmann L; Soukou S; Steglich B; Czarnewski P; Zhao L; Wende S; Bedke T; Ergen C; Manthey C; Agalioti T; Geffken M; Seiz O; Parigi SM; Sorini C; Geginat J; Fujio K; Jacobs T; Roesch T; Izbicki JR; Lohse AW; Flavell RA; Krebs C; Gustafsson J-A; Antonson P; Roncarolo MG; Villablanca EJ; Gagliani N; Huber S
Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2018;471:33-41

Genomics of sex hormone receptor signaling in hepatic sexual dimorphism.

Zheng D; Wang X; Antonson P; Gustafsson J-Å; Li Z
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017;114(48):E10428-E10437

Role of estrogen receptor beta in neural differentiation of mouse embryonic stem cells.

Varshney MK; Inzunza J; Lupu D; Ganapathy V; Antonson P; Rüegg J; Nalvarte I; Gustafsson J-Å
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017;114(19):E3816-E3822

Estrogen receptor β, a regulator of androgen receptor signaling in the mouse ventral prostate.

Wu W-F; Maneix L; Insunza J; Nalvarte I; Antonson P; Kere J; Yu NY-L; Tohonen V; Katayama S; Einarsdottir E; Krjutskov K; Dai Y-B; Huang B; Su W; Warner M; Gustafsson J-Å
Article: METHODS IN MOLECULAR BIOLOGY. 2016;1366:425-430

Estrogen Receptor-α Knockout Mice.

Antonson P; Humire P; Gustafsson J-Å
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2015;466(4):650-655

Identification of proteins highly expressed in uterine fluid from mice with hydrometra.

Antonson P; Nalvarte I; Varshney M; Xu L; Windahl SH; Humire P; Ohlsson C; Gustafsson J-Å; Dahlman-Wright K
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(16):5135-5140

Estrogen receptor β exon 3-deleted mouse: The importance of non-ERE pathways in ERβ signaling.

Maneix L; Antonson P; Humire P; Rochel-Maia S; Castañeda J; Omoto Y; Kim H-J; Warner M; Gustafsson J-Å
Article: PLOS ONE. 2014;9(1):e85581

aP2-Cre-mediated inactivation of estrogen receptor alpha causes hydrometra.

Antonson P; Matic M; Portwood N; Kuiper RV; Bryzgalova G; Gao H; Windahl SH; Humire P; Ohlsson C; Berggren P-O; Gustafsson J-Å; Dahlman-Wright K
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(6):2294-2299

Estrogen receptor-α in osteocytes is important for trabecular bone formation in male mice.

Windahl SH; Börjesson AE; Farman HH; Engdahl C; Movérare-Skrtic S; Sjögren K; Lagerquist MK; Kindblom JM; Koskela A; Tuukkanen J; Divieti Pajevic P; Feng JQ; Dahlman-Wright K; Antonson P; Gustafsson J-Å; Ohlsson C
Article: PLOS ONE. 2013;8(2):e57458

Estrogen signalling and the metabolic syndrome: targeting the hepatic estrogen receptor alpha action.

Matic M; Bryzgalova G; Gao H; Antonson P; Humire P; Omoto Y; Portwood N; Pramfalk C; Efendic S; Berggren P-O; Gustafsson J-Å; Dahlman-Wright K
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2012;424(4):710-716

Generation of ERα-floxed and knockout mice using the Cre/LoxP system.

Antonson P; Omoto Y; Humire P; Gustafsson J-Å
Article: FEBS LETTERS. 2011;585(5):744-748

CIDEA interacts with liver X receptors in white fat cells.

Kulyté A; Pettersson AT; Antonson P; Stenson BM; Langin D; Gustafsson J-A; Staels B; Rydén M; Arner P; Laurencikiene J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2008;283(14):8995-9001

RAP250 is a coactivator in the transforming growth factor beta signaling pathway that interacts with Smad2 and Smad3.

Antonson P; Jakobsson T; Almlöf T; Guldevall K; Steffensen KR; Gustafsson J-A
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2005;280(52):42863-42876

The proto-oncoprotein SYT interacts with SYT-interacting protein/co-activator activator (SIP/CoAA), a human nuclear receptor co-activator with similarity to EWS and TLS/FUS family of proteins.

Perani M; Antonson P; Hamoudi R; Ingram CJE; Cooper CS; Garrett MD; Goodwin GH
Article: GENE. 2004;327(2):233-238

The human RAP250 gene: genomic structure and promoter analysis.

Antonson P; Al-Beidh F; Matthews J; Gustafsson J-A
Article: MOLECULAR AND CELLULAR BIOLOGY. 2003;23(4):1260-1268

Inactivation of the nuclear receptor coactivator RAP250 in mice results in placental vascular dysfunction.

Antonson P; Schuster GU; Wang L; Rozell B; Holter E; Flodby P; Treuter E; Holmgren L; Gustafsson J-A
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(8):5308-5317

Cloning and characterization of RAP250, a novel nuclear receptor coactivator.

Caira F; Antonson P; Pelto-Huikko M; Treuter E; Gustafsson JA
Article: HUMAN MOLECULAR GENETICS. 1997;6(9):1559-1564

The SYT protein involved in the t(X;18) synovial sarcoma translocation is a transcriptional activator localised in nuclear bodies.

Brett D; Whitehouse S; Antonson P; Shipley J; Cooper C; Goodwin G
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1997;94(12):6462-6467

CCAAT/enhancer binding protein epsilon is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicing.

Yamanaka R; Kim GD; Radomska HS; Lekstrom-Himes J; Smith LT; Antonson P; Tenen DG; Xanthopoulos KG
Article: GENOMICS. 1996;35(1):30-38

A novel human CCAAT/enhancer binding protein gene, C/EBPepsilon, is expressed in cells of lymphoid and myeloid lineages and is localized on chromosome 14q11.2 close to the T-cell receptor alpha/delta locus.

Antonson P; Stellan B; Yamanaka R; Xanthopoulos KG
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1995;215(1):106-113

Molecular cloning, sequence, and expression patterns of the human gene encoding CCAAT/enhancer binding protein alpha (C/EBP alpha).

Antonson P; Xanthopoulos KG
Article: FEBS JOURNAL. 1995;232(2):397-403

Myc inhibits CCAAT/enhancer-binding protein alpha-gene expression in HIB-1B hibernoma cells through interactions with the core promoter region.

Antonson P; Pray MG; Jacobsson A; Xanthopoulos KG
Journal article: EXPERIMENTAL CELL RESEARCH. 1993;208(1):248-256

Differential patterns of expression of three C/EBP isoforms, HNF-1, and HNF-4 after partial hepatectomy in rats.

Flodby P; Antonson P; Barlow C; Blanck A; Porsch-Hällström I; Xanthopoulos KG
Journal article: NUCLEIC ACIDS RESEARCH. 1993;21(8):1735-1742

High level activity of the mouse CCAAT/enhancer binding protein (C/EBP alpha) gene promoter involves autoregulation and several ubiquitous transcription factors.

Legraverend C; Antonson P; Flodby P; Xanthopoulos KG
Journal article: FEBS LETTERS. 1993;318(3):235-241

Differential adrenergic regulation of C/EBP alpha and C/EBP beta in brown adipose tissue.

Rehnmark S; Antonson P; Xanthopoulos KG; Jacobsson A
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All other publications

Review: ENDOCRINOLOGY. 2023;164(6):bqad063

ERβ in Granulosa Cell Tumors and Its Clinical Potential.

Birgersson M; Indukuri R; Antonson P; Nalvarte I; Archer A; Williams C
Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51:89

Liver X receptor activation promotes intestinal repair while limiting tumorigenesis

Das S; Parigi SM; Scharaw S; Luo X; Diaz OE; Webb A; Zagami C; Pelczar P; De La Fuente M; Czarnewski P; Lopez Kostner F; Nylen S; Antonson P; Hermoso MA; Huber S; Gustafsson JA; Katajisto P; Villablanca EJ
Preprint: BIORXIV. 2019

Liver X Receptor regulates Th17 and RORγt⁺ Treg cells by distinct mechanisms

Parigi S; Das S; Frede A; Cardoso R; Tripathi KP; Doñas C; Hu Y; Antonson P; Engstrand L; Gustafsson J-Å; Villablanca E
Corrigendum: PLOS ONE. 2019;14(6):e0217526

Correction: Estrogen Signalling and the Metabolic Syndrome: Targeting the Hepatic Estrogen Receptor Alpha Action.

Matic M; Bryzgalova G; Gao H; Antonson P; Humire P; Omoto Y; Portwood N; Pramfalk C; Efendic S; Berggren P-O; Gustafsson J-Å; Dahlman-Wright K
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):293

Linking cholesterol metabolism and intestinal immunity through liver-X-receptor

Parigi SM; Das S; Barenco PVC; Sorini C; Perez OD; Antonson P; Gustafsson J-A; Villablanca EJ
Conference publication: CANCER RESEARCH. 2014;74(19):2118

Differential efficiency in the deletion of estrogen receptor β DNA binding domain generates distinct phenotypes in the mouse ventral prostate and ovary

Maneix L; Antonson P; Rochel-Maia SS; Kim H-J; Warner M; Gustafsson J-A
Conference publication: JOURNAL OF CELLULAR BIOCHEMISTRY. 1994;:169

DIFFERENTIAL REGULATION OF C/EBP-ALPHA AND C/EBP-BETA IN BROWN ADIPOSE-TISSUE - A SHIFT IN INTRACELLULAR MEDIATION DURING DIFFERENTIATION

JACOBSEN A; ANTONSON P; XANTHOPOULOS KG; REHNMARK S

Grants

Tissue-specific estrogen signaling - new insights in metabolic disease development

Swedish Research Council

1 January 2014 - 31 December 2016
Tissue-specific estrogen signaling- new insights in metabolic disease development

Swedish Research Council

1 January 2011 - 31 December 2013

Employments

Senior Research Specialist, Department of Medicine, Huddinge, Karolinska Institutet, 2024-
Senior Research Specialist, Department of Biosciences and Nutrition, Karolinska Institutet, 2024-2024
Senior Research Specialist, Department of Biosciences and Nutrition, Karolinska Institutet, 2022-2024

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