Denna sida på svenska
Loading profile information...

Publications

Cancer as an ecomolecular disease and a neoplastic consortium
Ramón Y Cajal S, Capdevila C, Hernandez-losa J, De Mattos-arruda L, Ghosh A, Lorent J, et al
Biochimica et biophysica acta 2017;1868(2):484-499

mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1
Morita M, Prudent J, Basu K, Goyon V, Katsumura S, Hulea L, et al
Molecular cell 2017;67(6):922-935.e5

mTOR-sensitive translation: Cleared fog reveals more trees
Masvidal L, Hulea L, Furic L, Topisirovic I, Larsson O
RNA biology 2017;():1-7

Polysome-profiling in small tissue samples
Liang S, Bellato Hm, Lorent J, Lupinacci Fcs, Oertlin C, Van Hoef V, et al
Nucleic acids research 2017;():-

iGEMS: an integrated model for identification of alternative exon usage events
Sood S, Szkop Kj, Nakhuda A, Gallagher Ij, Murie C, Brogan Rj, et al
Nucleic acids research 2016;44(11):e109-

IL-15 activates mTOR and primes stress-activated gene expression leading to prolonged antitumor capacity of NK cells
Mao Y, Van Hoef V, Zhang X, Wennerberg E, Lorent J, Witt K, et al
Blood 2016;128(11):1475-89

mTORC1 and CK2 coordinate ternary and eIF4F complex assembly
Gandin V, Masvidal L, Cargnello M, Gyenis L, Mclaughlan S, Cai Y, et al
Nature communications 2016;7():11127-

nanoCAGE reveals 5' UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs
Gandin V, Masvidal L, Hulea L, Gravel Sp, Cargnello M, Mclaughlan S, et al
Genome research 2016;26(5):636-48

Pericyte-fibroblast transition promotes tumor growth and metastasis
Hosaka K, Yang Y, Seki T, Fischer C, Dubey O, Fredlund E, et al
Proceedings of the National Academy of Sciences of the United States of America 2016;113(38):E5618-27

Tumor cell survival dependence on the DHX9 DExH-box helicase
Lee T, Paquet M, Larsson O, Pelletier J
Oncogene 2016;35(39):5093-105

Assessment of mTOR-Dependent Translational Regulation of Interferon Stimulated Genes
Livingstone M, Sikström K, Robert Pa, Uzé G, Larsson O, Pellegrini S
PloS one 2015;10(7):e0133482-

A stringent validation of mouse adipose tissue identity markers
De Jong Jm, Larsson O, Cannon B, Nedergaard J
American journal of physiology. Endocrinology and metabolism 2015;308(12):E1085-105

Estrogen receptor alpha drives proliferation in PTEN-deficient prostate carcinoma by stimulating survival signaling, MYC expression and altering glucose sensitivity
Takizawa I, Lawrence Mg, Balanathan P, Rebello R, Pearson Hb, Garg E, et al
Oncotarget 2015;6(2):604-16

mTOR coordinates protein synthesis, mitochondrial activity and proliferation
Morita M, Gravel Sp, Hulea L, Larsson O, Pollak M, St-pierre J, et al
Cell cycle (Georgetown, Tex.) 2015;14(4):473-80

Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3
Robichaud N, Del Rincon Sv, Huor B, Alain T, Petruccelli La, Hearnden J, et al
Oncogene 2015;34(16):2032-42

A pro-tumourigenic loop at the human prostate tumour interface orchestrated by oestrogen, CXCL12 and mast cell recruitment
Ellem Sj, Taylor Ra, Furic L, Larsson O, Frydenberg M, Pook D, et al
The Journal of pathology 2014;234(1):86-98

Correlation of Regional Emphysema and Lung Cancer A Lung Tissue Research Consortium-Based Study
Hohberger La, Schroeder Dr, Bartholmai Bj, Yang P, Wendt Ch, Bitterman Pb, et al
JOURNAL OF THORACIC ONCOLOGY 2014;9(5):639-45

Fibrotic extracellular matrix activates a profibrotic positive feedback loop
Parker Mw, Rossi D, Peterson M, Smith K, Sikström K, White Es, et al
The Journal of clinical investigation 2014;124(4):1622-35

Identification of a cell-of-origin for fibroblasts comprising the fibrotic reticulum in idiopathic pulmonary fibrosis
Xia H, Bodempudi V, Benyumov A, Hergert P, Tank D, Herrera J, et al
The American journal of pathology 2014;184(5):1369-83

Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner
Miloslavski R, Cohen E, Avraham A, Iluz Y, Hayouka Z, Kasir J, et al
Journal of molecular cell biology 2014;6(3):255-66

Polysome fractionation and analysis of mammalian translatomes on a genome-wide scale
Gandin V, Sikström K, Alain T, Morita M, Mclaughlan S, Larsson O, et al
Journal of visualized experiments : JoVE 2014;(87):-

Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner
Lee T, Di Paola D, Malina A, Mills Jr, Kreps A, Grosse F, et al
The Journal of biological chemistry 2014;289(33):22798-814

Translational control of immune responses: from transcripts to translatomes
Piccirillo Ca, Bjur E, Topisirovic I, Sonenberg N, Larsson O
Nature immunology 2014;15(6):503-11

Distinct translational control in CD4+ T cell subsets
Bjur E, Larsson O, Yurchenko E, Zheng L, Gandin V, Topisirovic I, et al
PLoS genetics 2013;9(5):e1003494-

Hedgehog signaling is active in human prostate cancer stroma and regulates proliferation and differentiation of adjacent epithelium
Wilkinson Se, Furic L, Buchanan G, Larsson O, Pedersen J, Frydenberg M, et al
The Prostate 2013;73(16):1810-23

mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation
Morita M, Gravel Sp, Chénard V, Sikström K, Zheng L, Alain T, et al
Cell metabolism 2013;18(5):698-711

Re-analysis of genome wide data on mammalian microRNA-mediated suppression of gene expression
Larsson O, Nadon R
Translation (Austin, Tex.) 2013;1(1):e24557-

RNAi screening uncovers Dhx9 as a modifier of ABT-737 resistance in an Eμ-myc/Bcl-2 mouse model
Mills Jr, Malina A, Lee T, Di Paola D, Larsson O, Miething C, et al
Blood 2013;121(17):3402-12

Toward a genome-wide landscape of translational control
Larsson O, Tian B, Sonenberg N
Cold Spring Harbor perspectives in biology 2013;5(1):a012302-

Tumour PDGF-BB expression levels determine dual effects of anti-PDGF drugs on vascular remodelling and metastasis
Hosaka K, Yang Y, Seki T, Nakamura M, Andersson P, Rouhi P, et al
Nature communications 2013;4():2129-

A Novel 4EHP-GIGYF2 Translational Repressor Complex Is Essential for Mammalian Development
Morita M, Ler Lw, Fabian Mr, Siddiqui N, Mullin M, Henderson Vc, et al
MOLECULAR AND CELLULAR BIOLOGY 2012;32(17):3585-93

Data-driven unbiased curation of the TP53 tumor suppressor gene mutation database and validation by ultradeep sequencing of human tumors
Edlund K, Larsson O, Ameur A, Bunikis I, Gyllensten U, Leroy B, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2012;109(24):9551-6

Distinct perturbation of the translatome by the antidiabetic drug metformin
Larsson O, Morita M, Topisirovic I, Alain T, Blouin Mj, Pollak M, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2012;109(23):8977-82

PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells
Xue Y, Lim S, Yang Yl, Wang Zw, Jensen Lde, Hedlund Em, et al
NATURE MEDICINE 2012;18(1):100-10

anota: analysis of differential translation in genome-wide studies
Larsson O, Sonenberg N, Nadon R
BIOINFORMATICS 2011;27(10):1440-1

Leishmania Repression of Host Translation through mTOR Cleavage Is Required for Parasite Survival and Infection
Jaramillo M, Gomez Ma, Larsson O, Shio Mt, Topisirovic I, Contreras I, et al
CELL HOST & MICROBE 2011;9(4):331-41

eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression
Furic L, Rong Lw, Larsson O, Koumakpayi Ih, Yoshida K, Brueschke A, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2010;107(32):14134-9

Identification of differential translation in genome wide studies
Larsson O, Sonenberg N, Nadon R
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2010;107(50):21487-92

mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs
Dowling Rjo, Topisirovic I, Alain T, Bidinosti M, Fonseca Bd, Petroulakis E, et al
SCIENCE 2010;328(5982):1172-6

A Chemical Genetic Screen for mTOR Pathway Inhibitors Based on 4E-BP-Dependent Nuclear Accumulation of eIF4E
Livingstone M, Larsson O, Sukarieh R, Pelletier J, Sonenberg N
CHEMISTRY & BIOLOGY 2009;16(12):1240-9

Eukaryotic Initiation Factor 4E Binding Protein Family of Proteins: Sentinels at a Translational Control Checkpoint in Lung Tumor Defense
Kim Yy, Von Weymarn L, Larsson O, Fan Dh, Underwood Jm, Peterson Ms, et al
CANCER RESEARCH 2009;69(21):8455-62

Hypoxia-Independent Angiogenesis in Adipose Tissues during Cold Acclimation
Xue Y, Petrovic N, Cao Rh, Larsson O, Lim S, Chen S, et al
CELL METABOLISM 2009;9(1):99-109

Insulin Receptor Expression by Human Prostate Cancers
Cox Me, Gleave Me, Zakikhani M, Bell Rh, Piura E, Vickers E, et al
PROSTATE 2009;69(1):33-40

p53-Dependent Translational Control of Senescence and Transformation via 4E-BPs
Petroulakis E, Parsyan A, Dowling Rjo, Lebacquer O, Martineau Y, Bidinosti M, et al
CANCER CELL 2009;16(5):439-46

Regulatory element identification in subsets of transcripts: Comparison and integration of current computational methods
Fan Dh, Bitterman Pb, Larsson O
RNA-A PUBLICATION OF THE RNA SOCIETY 2009;15(8):1469-82

Role of 3 ' UTRs in the Translation of mRNAs Regulated by Oncogenic eIF4E-A Computational Inference
Santhanam An, Bindewald E, Rajasekhar Vk, Larsson O, Sonenberg N, Colburn Nh, et al
PLOS ONE 2009;4(3):e4868-

The helicase protein DHX29 promotes translation initiation, cell proliferation, and tumorigenesis
Parsyan A, Shahbazian D, Martineau Y, Petroulakis E, Alain T, Larsson O, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2009;106(52):22217-22

USING FUNCTIONAL GENOMICS TO STUDY PINK1 AND METABOLIC PHYSIOLOGY
Scheele C, Larsson O, Timmons Ja
METHODS IN ENZYMOLOGY, VOL 457: MITOCHONDRIAL FUNCTION, PARTB MITOCHONDRIAL PROTEIN KINASES, PROTEIN PHOSPHATASES AND MITOCHONDRIAL DISEASES 2009;:211-29

Conserved GU-rich elements mediate mRNA decay by binding to CUG-binding protein 1
Vlasova Ia, Tahoe Nm, Fan D, Larsson O, Rattenbacher B, John Jrs, et al
MOLECULAR CELL 2008;29(2):263-70

Fibrotic Myofibroblasts Manifest Genome-Wide Derangements of Translational Control
Larsson O, Diebold D, Fan Dh, Peterson M, Nho Rs, Bitterman Pb, et al
PLOS ONE 2008;3(9):e3220-

Gene Expression - Time to Change Point of View?
Larsson O, Nadon R
BIOTECHNOLOGY AND GENETIC ENGINEERING REVIEWS, VOL 25 2008;:77-92

Translational control of the innate immune response through IRF-7
Colina R, Costa-mattioli M, Dowling Rjo, Jaramillo M, Tai Lh, Breitbach Cj, et al
NATURE 2008;452(7185):323-8

Altered regulation of the PINK1 locus: a link between type 2 diabetes and neurodegeneration?
Scheele C, Nielsen Ar, Walden Tb, Sewell Da, Fischer Cp, Brogan Rj, et al
FASEB JOURNAL 2007;21(13):3653-65

Epigenetic Activation of a Subset of mRNAs by eIF4E Explains Its Effects on Cell Proliferation
Mamane Y, Petroulakis E, Martineau Y, Sato Ta, Larsson O, Rajasekhar Vk, et al
PLOS ONE 2007;2(2):e242-

Eukaryotic translation initiation factor 4E-Induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors
Larsson O, Li S, Issaenko Oa, Avdulov S, Peterson M, Smith K, et al
CANCER RESEARCH 2007;67(14):6814-24

Improved precision and accuracy for microarrays using updated probe set definitions
Sandberg R, Larsson O
BMC BIOINFORMATICS 2007;:48-

Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages
Timmons Ja, Wennmalm K, Larsson O, Walden Tb, Lassmann T, Petrovic N, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2007;104(11):4401-6

Apoptosis resistance downstream of eIF4E: posttranscriptional activation of an anti-apoptotic transcript carrying a consensus hairpin structure
Larsson O, Perlman Dm, Fan Dh, Reilly Cs, Peterson M, Dahlgren C, et al
NUCLEIC ACIDS RESEARCH 2006;34(16):4375-86

Comparative microarray analysis
Larsson O, Wennmalm K, Sandberg R
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY 2006;10(3):381-97

Lack of correct data format and comparability limits future integrative microarray research
Larsson O, Sandberg R
NATURE BIOTECHNOLOGY 2006;24(11):1322-3

Considerations when using the significance analysis of microarrays (SAM) algorithm
Larsson O, Wahlestedt C, Timmons Ja
BMC BIOINFORMATICS 2005;:129-

DNA immobilization: Silanized nucleic acids and nanoprinting
Du Q, Larsson O, Swerdlow H, Liang Z
IMMOBILISATION OF DNA ON CHIPS II 2005;:45-61

Human muscle gene expression responses to endurance training provide a novel perspective on Duchenne muscular dystrophy
Timmons Ja, Larsson O, Jansson E, Fischer H, Gustafsson T, Greenhaff Pl, et al
FASEB JOURNAL 2005;19(7):750-60

The expression signature of in vitro senescence resembles mouse but not human aging
Wennmalm K, Wahlestedt C, Larsson O
GENOME BIOLOGY 2005;6(13):R109-

Functional comparison of single- and double-stranded siRNAs in mammalian cells
Xu Yh, Linde A, Larsson A, Thormeyer D, Elmen J, Wahlestedt C, et al
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2004;316(3):680-7

Kinetics of senescence-associated changes of gene expression in an epithelial, temperature-sensitive SV40 large T antigen model
Larsson O, Scheele C, Liang Zc, Moll J, Karlsson C, Wahlestedt C
CANCER RESEARCH 2004;64(2):482-9

Characterization of lacZ complementation deletions using membrane receptor dimerization
Thormeyer D, Ammerpohl O, Larsson O, Xu Y, Asinger A, Wahlestedt C, et al
BIOTECHNIQUES 2003;34(2):346-50

Effective small interfering RNAs and phosphorothioate antisense DNAs have different preferences for target sites in the luciferase mRNAs
Xu Yh, Zhang Hy, Thormeyer D, Larsson A, Du Q, Elmen J, et al
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2003;306(3):712-7

Quantitative codon optimisation of DNA libraries encoding sub-random peptides: design and characterisation of a novel library encoding transmembrane domain peptides
Larsson O, Thormeyer D, Asinger A, Wihlen B, Wahlestedt C, Liang Z
NUCLEIC ACIDS RESEARCH 2002;30(23):e133-

Bactericidal antisense effects of peptide-PNA conjugates
Good L, Awasthi Sk, Dryselius R, Larsson O, Nielsen Pe
NATURE BIOTECHNOLOGY 2001;19(4):360-4

Antisense PNA effects in Escherichia coli are limited by the outer-membrane LPS layer
Good L, Sandberg R, Larsson O, Nielsen Pe, Wahlestedt C
MICROBIOLOGY-SGM 2000;:2665-70

Silanized nucleic acids: a general platform for DNA immobilization
Kumar A, Larsson O, Parodi D, Liang Z
Nucleic acids research 2000;28(14):E71-

Show all publications