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Gunilla Karlsson Hedestam

Professor

Visiting address : Nobels väg 16, 171 77 Stockholm, Sweden
Postal address : Department of Microbiology, Tumor and Cell Biology (MTC), C1, Gunilla Karlsson Hedestam group, Box 280 171 77 Stockholm, Sweden

Publications

Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Primates Neutralize Primary Human Immunodeficiency Viruses (HIV-1) Sensitized by CD4-Mimetic Compounds
Madani N, Princiotto Am, Easterhoff D, Bradley T, Luo K, Williams Wb, et al
Journal of virology 2016;90(10):5031-46

Heterozygous Mutation in IκBNS Leads to Reduced Levels of Natural IgM Antibodies and Impaired Responses to T-Independent Type 2 Antigens
Pedersen Gk, Ádori M, Stark Jm, Khoenkhoen S, Arnold C, Beutler B, et al
Frontiers in immunology 2016;7():65-

HIV-1 Vaccine-elicited Antibodies Reverted to Their Inferred Naive Germline Reveal Associations between Binding Affinity and in vivo Activation
Dai K, Khan Sn, Wang Y, He L, Guenaga J, Ingale J, et al
Scientific reports 2016;6():20987-

Diverse antibody genetic and recognition properties revealed following HIV-1 envelope glycoprotein immunization
Phad Ge, Vázquez Bernat N, Feng Y, Ingale J, Martinez Murillo Pa, O'dell S, et al
Journal of immunology (Baltimore, Md. : 1950) 2015;194(12):5903-14

Interleukin-21-Producing CD4(+) T Cells Promote Type 2 Immunity to House Dust Mites
Coquet Jm, Schuijs Mj, Smyth Mj, Deswarte K, Beyaert R, Braun H, et al
Immunity 2015;43(2):318-30

NF-κB signaling in B-1 cell development
Pedersen Gk, Ádori M, Karlsson Hedestam Gb
Annals of the New York Academy of Sciences 2015;1362():39-47

Primate immune responses to HIV-1 Env formulated in the saponin-based adjuvant AbISCO-100 in the presence or absence of TLR9 co-stimulation
Martinez P, Sundling C, O'dell S, Mascola Jr, Wyatt Rt, Karlsson Hedestam Gb
Scientific reports 2015;5():8925-

Protection of human myeloid dendritic cell subsets against influenza A virus infection is differentially regulated upon TLR stimulation
Baharom F, Thomas S, Bieder A, Hellmér M, Volz J, Sandgren Kj, et al
Journal of immunology (Baltimore, Md. : 1950) 2015;194(9):4422-30

Real-time resolution of point mutations that cause phenovariance in mice
Wang T, Zhan X, Bu Ch, Lyon S, Pratt D, Hildebrand S, et al
Proceedings of the National Academy of Sciences of the United States of America 2015;112(5):E440-9

Rhesus Macaque B-Cell Responses to an HIV-1 Trimer Vaccine Revealed by Unbiased Longitudinal Repertoire Analysis
Dai K, He L, Khan Sn, O'dell S, Mckee K, Tran K, et al
mBio 2015;6(6):e01375-15

Robust Neutralizing Antibodies Elicited by HIV-1 JRFL Envelope Glycoprotein Trimers in Nonhuman Primates (vol 87, pg 13239, 2013)
Chakrabarti Bk, Feng Y, Sharma Sk, Mckee K, Hedestam Gbk, Labranche Cc, et al
JOURNAL OF VIROLOGY 2015;89(1):887-887

Slc15a4 function is required for intact class switch recombination to IgG2c in response to TLR9 stimulation
Dosenovic P, Ádori M, Adams Wc, Pedersen Gk, Soldemo M, Beutler B, et al
Immunology and cell biology 2015;93(2):136-46

A simple and safe technique for longitudinal bone marrow aspiration in cynomolgus and rhesus macaques
Spångberg M, Martinez P, Fredlund H, Karlsson Hedestam Gb, Sundling C
Journal of immunological methods 2014;408():137-41

B-1a transitional cells are phenotypically distinct and are lacking in mice deficient in IκBNS
Pedersen Gk, Àdori M, Khoenkhoen S, Dosenovic P, Beutler B, Karlsson Hedestam Gb
Proceedings of the National Academy of Sciences of the United States of America 2014;111(39):E4119-26

Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants
Klein F, Nogueira L, Nishimura Y, Phad G, West Ap, Halper-stromberg A, et al
The Journal of experimental medicine 2014;211(12):2361-72

HIV-1 Env-specific memory and germinal center B cells in C57BL/6 mice
Soldemo M, Pedersen Gk, Karlsson Hedestam Gb
Viruses 2014;6(9):3400-14

HIV-1 receptor binding site-directed antibodies using a VH1-2 gene segment orthologue are activated by Env trimer immunization
Navis M, Tran K, Bale S, Phad Ge, Guenaga J, Wilson R, et al
PLoS pathogens 2014;10(8):e1004337-

MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses
Zeng M, Hu Z, Shi X, Li X, Zhan X, Li Xd, et al
Science (New York, N.Y.) 2014;346(6216):1486-92

Single-cell and deep sequencing of IgG-switched macaque B cells reveal a diverse Ig repertoire following immunization
Sundling C, Zhang Z, Phad Ge, Sheng Z, Wang Y, Mascola Jr, et al
Journal of immunology (Baltimore, Md. : 1950) 2014;192(8):3637-44

Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign
Tran K, Poulsen C, Guenaga J, De Val N, Wilson R, Sundling C, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2014;111(7):E738-47

Chemical cross-linking of HIV-1 Env for direct TLR7/8 ligand conjugation compromises recognition of conserved antigenic determinants
Feng Y, Forsell Mne, Flynn B, Adams W, Lore K, Seder R, et al
VIROLOGY 2013;446(1-2):56-65

Human plasmacytoid dendritic cells efficiently capture HIV-1 envelope glycoproteins via CD4 for antigen presentation
Sandgren Kj, Smed-sörensen A, Forsell Mn, Soldemo M, Adams Wc, Liang F, et al
Journal of immunology (Baltimore, Md. : 1950) 2013;191(1):60-9

Immunization of macaques with soluble HIV type 1 and influenza virus envelope glycoproteins results in a similarly rapid contraction of peripheral B-cell responses after boosting
Sundling C, Martinez P, Soldemo M, Spångberg M, Bengtsson Kl, Stertman L, et al
The Journal of infectious diseases 2013;207(3):426-31

Independent expansion of epitope-specific plasma cell responses upon HIV-1 envelope glycoprotein immunization
Forsell Mn, Soldemo M, Dosenovic P, Wyatt Rt, Karlsson Mc, Karlsson Hedestam Gb
Journal of immunology (Baltimore, Md. : 1950) 2013;191(1):44-51

Influenza A virus-mediated priming enhances cytokine secretion by human dendritic cells infected with Streptococcus pneumoniae
Kuri T, Sörensen As, Thomas S, Karlsson Hedestam Gb, Normark S, Henriques-normark B, et al
Cellular microbiology 2013;15(8):1385-400

Robust Neutralizing Antibodies Elicited by HIV-1 JRFL Envelope Glycoprotein Trimers in Nonhuman Primates
Chakrabarti Bk, Feng Y, Sharma Sk, Mckee K, Hedestam Gbk, Labranche Cc, et al
JOURNAL OF VIROLOGY 2013;87(24):13239-51

Accumulation of Autophagosomes in Semliki Forest Virus-Infected Cells Is Dependent on Expression of the Viral Glycoproteins
Eng Ke, Panas Md, Murphy D, Hedestam Gbk, Mcinerney Gm
JOURNAL OF VIROLOGY 2012;86(10):5674-85

A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity
Arnold Cn, Pirie E, Dosenovic P, Mcinerney Gm, Xia Y, Wang N, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2012;109(31):12286-93

Attenuation of CD4(+) T-cell function by human adenovirus type 35 is mediated by the knob protein
Adams Wc, Berenson Rj, Hedestam Gbk, Lieber A, Koup Ra, Lore K
JOURNAL OF GENERAL VIROLOGY 2012;:1339-44

Biochemically Defined HIV-1 Envelope Glycoprotein Variant Immunogens Display Differential Binding and Neutralizing Specificities to the CD4-binding Site
Feng Y, Mckee K, Tran K, O'dell S, Schmidt Sd, Phogat A, et al
JOURNAL OF BIOLOGICAL CHEMISTRY 2012;287(8):5673-86

BLyS-Mediated Modulation of Naive B Cell Subsets Impacts HIV Env-Induced Antibody Responses
Dosenovic P, Soldemo M, Scholz Jl, O'dell S, Grasset Ek, Pelletier N, et al
JOURNAL OF IMMUNOLOGY 2012;188(12):6018-26

High-Resolution Definition of Vaccine-Elicited B Cell Responses Against the HIV Primary Receptor Binding Site
Sundling C, Li Yx, Huynh N, Poulsen C, Wilson R, O'dell S, et al
SCIENCE TRANSLATIONAL MEDICINE 2012;4(142):142ra96-

Isolation of antibody V(D)J sequences from single cell sorted rhesus macaque B cells
Sundling C, Phad G, Douagi I, Navis M, Karlsson Hedestam Gb
Journal of immunological methods 2012;386(1-2):85-93

Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection
Panas Md, Varjak M, Lulla A, Eng Ke, Merits A, Karlsson Hedestam Gb, et al
Molecular biology of the cell 2012;23(24):4701-12

Adenovirus type-35 vectors block human CD4(+) T-cell activation via CD46 ligation
Adams Wc, Gujer C, Mcinerney G, Gall Jgd, Petrovas C, Hedestam Gbk, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2011;108(18):7499-504

Heterologous Epitope-Scaffold Prime:Boosting Immuno-Focuses B Cell Responses to the HIV-1 gp41 2F5 Neutralization Determinant
Guenaga J, Dosenovic P, Ofek G, Baker D, Schief Wr, Kwong Pd, et al
PLOS ONE 2011;6(1):e16074-

Human and rhesus plasmacytoid dendritic cell and B-cell responses to Toll-like receptor stimulation
Gujer C, Sundling C, Seder Ra, Hedestam Gbk, Lore K
IMMUNOLOGY 2011;134(3):257-69

IFN-alpha produced by human plasmacytoid dendritic cells enhances T cell-dependent naive B cell differentiation
Gujer C, Sandgren Kj, Douagi I, Adams Wc, Sundling C, Smed-sorensen A, et al
JOURNAL OF LEUKOCYTE BIOLOGY 2011;89(6):811-21

A mutation of Ikbkg causes immune deficiency without impairing degradation of I kappa B alpha
Siggs Om, Berger M, Krebs P, Arnold Cn, Eidenschenk C, Huber C, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2010;107(7):3046-51

A novel quantitative flow cytometry-based assay for autophagy
Eng Ke, Panas Md, Hedestam Gbk, Mcinerney Gm
AUTOPHAGY 2010;6(5):634-41

Immunization with Wild-Type or CD4-Binding-Defective HIV-1 Env Trimers Reduces Viremia Equivalently following Heterologous Challenge with Simian-Human Immunodeficiency Virus
Sundling C, O'dell S, Douagi I, Forsell Mn, Morner A, Lore K, et al
JOURNAL OF VIROLOGY 2010;84(18):9086-95

Influence of Novel CD4 Binding-Defective HIV-1 Envelope Glycoprotein Immunogens on Neutralizing Antibody and T-Cell Responses in Nonhuman Primates
Douagi I, Forsell Mne, Sundling C, O'dell S, Feng Y, Dosenovic P, et al
JOURNAL OF VIROLOGY 2010;84(4):1683-95

Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates
Sundling C, Forsell Mne, O'dell S, Feng Y, Chakrabarti B, Rao Ss, et al
JOURNAL OF EXPERIMENTAL MEDICINE 2010;207(9):2003-17

Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates (vol 207, pg 2003, 2010)
Sundling C, Forsell Mne, O'dell S, Feng Y, Chakrabarti B, Rao Ss, et al
JOURNAL OF EXPERIMENTAL MEDICINE 2010;207(10):2283-2283

Adenovirus serotype 5 infects human dendritic cells via a coxsackievirus-adenovirus receptor-independent receptor pathway mediated by lactoferrin and DC-SIGN
Adams Wc, Bond E, Havenga Mje, Holterman L, Goudsmit J, Hedestam Gbk, et al
JOURNAL OF GENERAL VIROLOGY 2009;:1600-10

Analysis of antibody and B cell responses following inoculation with computationally designed HIV-1 2F5 epitope scaffold proteins
Dosenovic P, Guenaga J, Ofek G, Baker D, Schief W, Kwong Pd, et al
RETROVIROLOGY 2009;:-

Direct Cleavage, Proteasomal Degradation and Sequestration: Three Mechanisms of Viral Subversion of Type I Interferon Responses
Mcinerney Gm, Hedestam Gbk
JOURNAL OF INNATE IMMUNITY 2009;1(6):599-606

Human B Cell Responses to TLR Ligands Are Differentially Modulated by Myeloid and Plasmacytoid Dendritic Cells
Douagi I, Gujer C, Sundling C, Adams Wc, Smed-sorensen A, Seder Ra, et al
JOURNAL OF IMMUNOLOGY 2009;182(4):1991-2001

Human Immunodeficiency Virus Type 1 Env Trimer Immunization of Macaques and Impact of Priming with Viral Vector or Stabilized Core Protein
Morner A, Douagi I, Forsell Mne, Sundling C, Dosenovic P, O'dell S, et al
JOURNAL OF VIROLOGY 2009;83(2):540-51

Novel adjuvants for B cell immune responses
Lore K, Hedestam Gbk
CURRENT OPINION IN HIV AND AIDS 2009;4(5):441-6

Selective Expansion of HIV-1 Envelope Glycoprotein-Specific B Cell Subsets Recognizing Distinct Structural Elements Following Immunization
Dosenovic P, Chakrabarti B, Soldemo M, Douagi I, Forsell Mne, Li Yx, et al
JOURNAL OF IMMUNOLOGY 2009;183(5):3373-82

B Cell Recognition of the Conserved HIV-1 Co-Receptor Binding Site Is Altered by Endogenous Primate CD4
Forsell Mne, Dey B, Morner A, Svehla K, O'dell S, Hogerkorp Cm, et al
PLOS PATHOGENS 2008;4(10):e1000171-

CTA1-DD adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization
Sundling C, Schon K, Morner A, Forsell Mne, Wyatt Rt, Thorstensson R, et al
JOURNAL OF GENERAL VIROLOGY 2008;:2954-64

Human B cell responses to toll-like receptor ligands are differentially modulated by myloid and plasmacytoid dendritic cells
Douagi I, Gujer C, Sundling C, Adams Wc, Smed-sorensen A, Seder Ra, et al
SCANDINAVIAN JOURNAL OF IMMUNOLOGY 2008;68(2):238-238

Impact of In Vivo CD4 Binding Following HIV-1 Env Protein Trimer Immunizations of Rhesus Macaques
Douagi I, Forsell Mn, Sundling C, O'dell S, Dosenovic P, Li Y, et al
AIDS RESEARCH AND HUMAN RETROVIRUSES 2008;:45-46

The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus
Hedestam Gbk, Fouchier Ram, Phogat S, Burton Dr, Sodroski J, Wyatt Rt
NATURE REVIEWS MICROBIOLOGY 2008;6(2):143-55

Crystal structure of conserved domains 1 and 2 of the human DEAD-box helicase DDX3X in complex with the mononucleotide AMP
Hogbom M, Collins R, Van Den Berg S, Jenvert Rm, Karlberg T, Kotenyova T, et al
JOURNAL OF MOLECULAR BIOLOGY 2007;372(1):150-9

Increased human immunodeficiency virus type 1 Env expression and antibody induction using an enhanced alphavirus vector
Forsell Mne, Mcinerney Gm, Dosenovic P, Hidmark As, Eriksson C, Liljestorm P, et al
JOURNAL OF GENERAL VIROLOGY 2007;:2774-9

Inhibition of HIV-1 entry by antibodies: potential viral and cellular targets
Phogat S, Wyatt Rt, Hedestam Gbk
JOURNAL OF INTERNAL MEDICINE 2007;262(1):26-43

Role of interferon regulatory factor 3 in type I interferon responses in rotavirus-infected dendritic cells and fibroblasts
Douagi I, Mcinerney Ga, Hidmark As, Miriallis V, Johansen K, Svensson L, et al
JOURNAL OF VIROLOGY 2007;81(6):2758-68

Semliki forest virus nonstructural protein 2 is involved in suppression of the type I interferon response
Breakwell L, Dosenovic P, Hedestam Gbk, D'amato M, Liljestrom P, Fazakerley J, et al
JOURNAL OF VIROLOGY 2007;81(16):8677-84

DAP12 signaling regulates plasmacytoid dendritic cell homeostasis and down-modulates their function during viral infection (vol 177, pg 2908, 2006)
Sjolin H, Robbins Sh, Bessou G, Hidmark A, Tomasello E, Johansson M, et al
JOURNAL OF IMMUNOLOGY 2006;177(8):5748-5748

DAP12 signalling regulates plasmacytoid ddendritic cell homeostasis and down-modulates their function during viral infection
Sjolin H, Robbins Sh, Bessou G, Hidmark A, Tomasello E, Johansson M, et al
JOURNAL OF IMMUNOLOGY 2006;177(5):2908-16

DNA vaccines: Recent developments and future possibilities
Liu Ma, Wahren B, Hedestam Gbk
HUMAN GENE THERAPY 2006;17(11):1051-61

Humoral responses against coimmunized protein antigen but not against alphavirus-encoded antigens require alpha/beta interferon signaling
Hidmark As, Nordstrom Ekl, Dosenovic P, Forsell Mne, Liljestrom P, Hedestam Gbk
JOURNAL OF VIROLOGY 2006;80(14):7100-10

Biochemical and immunogenic characterization of soluble human immunodeficiency virus type 1 envelope glycoprotein trimers expressed by Semliki Forest virus
Forsell Mne, Li Yx, Sundback M, Svehla K, Liljestrom P, Mascola Jr, et al
JOURNAL OF VIROLOGY 2005;79(17):10902-14

Early alpha/beta interferon production by myeloid dendritic cells in response to UV-inactivated virus requires viral entry and interferon regulatory factor 3 but not MyD88
Hidmark As, Mcinerney Gm, Nordstrom Ekl, Douagi I, Werner Km, Liljestrom P, et al
JOURNAL OF VIROLOGY 2005;79(16):10376-85

Efficient expansion of HIV-1-specific T cell responses by homologous immunization with recombinant Semliki Forest virus particles
Sundback M, Douagi I, Dayaraj C, Forsell Mne, Nordstrom Ekl, Mcinerney Gm, et al
VIROLOGY 2005;341(2):190-202

Enhanced immunogenicity using an alphavirus replicon DNA vaccine against human immunodeficiency virus type 1
Nordstrom Ekl, Forsell Mne, Barnfield C, Bonin E, Hanke T, Sundstrom M, et al
JOURNAL OF GENERAL VIROLOGY 2005;:349-54

Activation of p53 by scaffold-stabilised expression of Mdm2-binding peptides: visualisation of reporter gene induction at the single-cell level
Karlsson Gb, Jensen A, Stevenson Lf, Woods Yl, Lane Dp, Sorensen Ms
BRITISH JOURNAL OF CANCER 2004;91(8):1488-94

Delivery and expression of heterologous genes in mammalian cells using self-replicating alphavirus vectors
Karlsson Gb, Liljeström P
Methods in molecular biology (Clifton, N.J.) 2004;246():543-57

Live viral vectors: Semliki Forest virus
Karlsson Gb, Liljeström P
Methods in molecular medicine 2003;87():69-82

Changes in human immunodeficiency virus type 1 envelope glycoproteins responsible for the pathogenicity of a multiply passaged simian-human immunodeficiency virus (SHIV-HXBc2)
Cayabyab M, Karlsson Gb, Etemad-moghadam Ba, Hofmann W, Steenbeke T, Halloran M, et al
JOURNAL OF VIROLOGY 1999;73(2):976-84

Determinants of neutralization resistance in the envelope glycoproteins of a simian-human immunodeficiency virus passaged in vivo
Etemad-moghadam B, Sun Y, Nicholson Ek, Karlsson Gb, Schenten D, Sodroski J
JOURNAL OF VIROLOGY 1999;73(10):8873-9

Effects of soluble CD4 on simian immunodeficiency virus infection of CD4-positive and CD4-negative
Schenten D, Marcon L, Karlsson Gb, Parolin C, Kodama T, Gerard N, et al
JOURNAL OF VIROLOGY 1999;73(7):5373-80

Viral burden and disease progression in rhesus monkeys infected with chimeric simian-human immunodeficiency viruses
Reimann Ka, Watson A, Dailey Pj, Lin Wy, Lord Ci, Steenbeke Td, et al
VIROLOGY 1999;256(1):15-21

Characterization of simian-human immunodeficiency virus envelope glycoprotein epitopes recognized by neutralizing antibodies from infected monkeys
Etemad-moghadam B, Karlsson Gb, Halloran M, Sun Y, Schenten D, Fernandes M, et al
JOURNAL OF VIROLOGY 1998;72(10):8437-45

The envelope glycoprotein ectodomains determine the efficiency of CD4(+) T lymphocyte depletion in simian-human immunodeficiency virus-infected macaques
Karlsson Gb, Halloran M, Schenten D, Lee J, Racz P, Tenner-racz K, et al
JOURNAL OF EXPERIMENTAL MEDICINE 1998;188(6):1159-71

Characterization of molecularly cloned simian human immunodeficiency viruses causing rapid CD4(+) lymphocyte depletion in rhesus monkeys
Karlsson Gb, Halloran M, Li J, Park Iw, Gomila R, Reimann Ka, et al
JOURNAL OF VIROLOGY 1997;71(6):4218-25

Immunoglobulin V-H usage during primary infection of rhesus monkeys with chimeric simian-human immunodeficiency viruses
Margolin Dh, Reimann Ka, Sodroski J, Karlsson Gb, Tennerracz K, Racz P, et al
JOURNAL OF VIROLOGY 1997;71(11):8582-91

Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection
Farzan M, Choe H, Martin K, Marcon L, Hofmann W, Karlsson G, et al
JOURNAL OF EXPERIMENTAL MEDICINE 1997;186(3):405-11

A chimeric simian/human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate env causes an AIDS-Like disease after in vivo passage in rhesus monkeys
Reimann Ka, Li Jt, Veazey R, Halloran M, Park Iw, Karlsson Gb, et al
JOURNAL OF VIROLOGY 1996;70(10):6922-8

Increased envelope spike density and stability are not required for the neutralization resistance of primary human immunodeficiency viruses
Karlsson Gb, Gao F, Robinson J, Hahn B, Sodroski J
JOURNAL OF VIROLOGY 1996;70(9):6136-42

Molecular cloning and analysis of functional envelope genes from human immunodeficiency virus type 1 sequence subtypes A through G
Gao F, Morrison Sg, Robertson Dl, Thornton Cl, Craig S, Karlsson G, et al
JOURNAL OF VIROLOGY 1996;70(3):1651-67

N-butyldeoxynojirimycin-mediated inhibition of human immunodeficiency virus entry correlates with changes in antibody recognition of the V1/V2 region of gp120
Fischer Pb, Karlsson Gb, Butters Td, Dwek Ra, Platt Fm
JOURNAL OF VIROLOGY 1996;70(10):7143-52

N-butyldeoxynojirimycin-mediated inhibition of human immunodeficiency virus entry correlates with impaired gp120 shedding and gp41 exposure
Fischer Pb, Karlsson Gb, Dwek Ra, Platt Fm
JOURNAL OF VIROLOGY 1996;70(10):7153-60

THE ALPHA-GLUCOSIDASE INHIBITOR N-BUTYLDEOXYNOJIRIMYCIN INHIBITS HUMAN-IMMUNODEFICIENCY-VIRUS ENTRY AT THE LEVEL OF POST-CD4-BINDING
Fischer P, Collin M, Karlsson Gb, James W, Butters Td, Davis Sj, et al
JOURNAL OF VIROLOGY 1995;69(9):5791-7

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