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Nele Brusselaers

Assistant professor

Visiting address : Nobels Väg 16 171 77 Stockholm, Sweden
Postal address : Department of Microbiology, Tumor and Cell Biology (MTC), C1, Lars Engstrand group, Box 280 171 77 Stockholm, Sweden
Delivery address : Nobels Väg 16 171 77 Stockholm, Sweden

About me

I am an Associate Professor of Clinical Epidemiology (Docent) at Karolinska Institutet, and Assistant Professor (FoAss) at the Centre for Translational Microbiome Research, Karolinska Insitutet. Although I have a broad interest and experience in different clinical topics; my main focus is to investigate the long-term effects of commonly prescribed drugs on female health and diseases of the gastro-intestinal tract.

I also teach and supervise students from undergraduate to doctoral level, and I am course organiser of 1 course at doctoral level (How to conduct systematic reviews and meta-analyses, course 2790).

I am also a member of the steering board of Junior Faculty and SFO epidemiology (both at Karolinska Institutet: see links)

Education

  • Master in Medicine (MD), Ghent University (Belgium), 2008.
  • PhD in Medical Sciences, Thesis: "Severe burn injury: Some determinants of epidemiological and surgical outcomes, Ghent University, Belgium, 2010.
  • Master in Hospital Hygiene and Infection Control, Ghent University (Belgium), 2010.
  • Master in Epidemiology, London School of Hygiene and Tropical Medicine (United Kingdom), 2015.
  • Docent in Clinical Epidemiology, Karolinska Institutet, 2015.
  • First post-doc: Dept of Internal medicine and Infectious diseases, Ghent University, Belgium (2010-2012)
  • Second post-doc: Upper-gastrointestinal surgery, Dept of Molecular medicine and Surgery, Karolinska Insitutet (2012-2016)

Teaching portfolio

Course organiser:

- How to conduct systematic reviews and meta-analyses (KI PhD course 2790), since 2014

- Study design in clinical research (KI PhD course 1794), 2013-2015

Undergraduate and postgraduate teaching at Karolinska Institutet and Ghent University, total > 800 hours (including supervision): including study design, systematic reviews and meta-analyses, and other basic and advanced topics within epidemiology and clinical research.

Academic honors, awards and prizes

Awarded research funding as prinicipal investigator:

Awarded research funding as co-applicant

  • KID funding: Karolinska Insitutet delfinansiering för nya doktorander (2014)
  • SIMSAM (Swedish Initiative for Research on Microdata in the Social and Medical Sciences) (2014-2018)

Publications

Antireflux Surgery and Risk of Esophageal Adenocarcinoma: A Systematic Review and Meta-analysis
Maret-ouda J, Konings P, Lagergren J, Brusselaers N
Annals of surgery 2016;263(2):251-7

Bacteriological cultures on admission of the burn patient: To do or not to do, that's the question
Dokter J, Brusselaers N, Hendriks Wd, Boxma H
Burns : journal of the International Society for Burn Injuries 2016;42(2):421-7

Comparison of the harmonic focus and the thunderbeat for open thyroidectomy
Van Slycke S, Gillardin Jp, Van Den Heede K, Minguet J, Vermeersch H, Brusselaers N
Langenbeck's archives of surgery 2016;401(6):851-9

Eradication of Helicobacter pylori and Gastric Cancer: A Systematic Review and Meta-analysis of Cohort Studies
Doorakkers E, Lagergren J, Engstrand L, Brusselaers N
Journal of the National Cancer Institute 2016;108(9):-

Mortality from laparoscopic antireflux surgery in a nationwide cohort of the working-age population
Maret-ouda J, Yanes M, Konings P, Brusselaers N, Lagergren J
The British journal of surgery 2016;103(7):863-70

Quantifying the outcome of surgical treatment of temporomandibular joint ankylosis: A systematic review and meta-analysis
De Roo N, Van Doorne L, Troch A, Vermeersch H, Brusselaers N
Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery 2016;44(1):6-15

Association between education level and prognosis after esophageal cancer surgery: a Swedish population-based cohort study
Brusselaers N, Mattsson F, Lindblad M, Lagergren J
PloS one 2015;10(3):e0121928-

Early complications following oesophagectomy for cancer in relation to long-term healthcare utilisation: a prospective population-based cohort study
Doorakkers E, Konings P, Mattsson F, Lagergren J, Brusselaers N
PloS one 2015;10(3):e0121080-

Epidemiology of invasive aspergillosis in critically ill patients: clinical presentation, underlying conditions, and outcomes
Taccone Fs, Van Den Abeele Am, Bulpa P, Misset B, Meersseman W, Cardoso T, et al
Critical care (London, England) 2015;19():7-

How to teach the fundamentals of meta-analyses
Brusselaers N
Annals of epidemiology 2015;25(12):948-54

Tumour staging of oesophageal cancer in the Swedish Cancer Registry: A nationwide validation study
Brusselaers N, Vall A, Mattsson F, Lagergren J
Acta oncologica (Stockholm, Sweden) 2015;54(6):903-8

What is the most effective treatment for severe gastro-oesophageal reflux disease?
Maret-ouda J, Brusselaers N, Lagergren J
BMJ (Clinical research ed.) 2015;350():h3169-

[Why oesophageal adenocarcinoma is occurring more frequently]
Doorakkers E, Brusselaers N
Nederlands tijdschrift voor geneeskunde 2015;159():A8915-

Cerebral aspergillosis in adult critically ill patients: a descriptive report of 10 patients from the AspICU cohort
Spapen H, Spapen J, Taccone Fs, Meersseman W, Rello J, Dimopoulos G, et al
International journal of antimicrobial agents 2014;43(2):165-9

Harlequin Syndrome after Thyroidectomy for Compressive Retrosternal Goiter. Case Report and Review of the Literature
Van Slycke S, Stockman A, Dionigi G, Carette R, Gillardin Jp, Brusselaers N, et al
ACTA CHIRURGICA BELGICA 2014;114(3):212-4

Hormone replacement therapy and oral contraceptives and risk of oesophageal adenocarcinoma: a systematic review and meta-analysis
Lagergren K, Lagergren J, Brusselaers N
International journal of cancer 2014;135(9):2183-90

Hospital and surgeon volume in relation to long-term survival after oesophagectomy: systematic review and meta-analysis
Brusselaers N, Mattsson F, Lagergren J
Gut 2014;63(9):1393-400

Marital status and survival after oesophageal cancer surgery: a population-based nationwide cohort study in Sweden
Brusselaers N, Mattsson F, Johar A, Wikman A, Lagergren P, Lagergren J, et al
BMJ open 2014;4(6):e005418-

Assessment of mortality prediction models in a Ghanaian burn population
Brusselaers N, Agbenorku P, Hoyte-williams Pe
BURNS 2013;39(5):997-1003

Clinical use of HIV integrase inhibitors: a systematic review and meta-analysis
Messiaen P, Wensing Am, Fun A, Nijhuis M, Brusselaers N, Vandekerckhove L
PloS one 2013;8(1):e52562-

Education level and survival after oesophageal cancer surgery: a prospective population-based cohort study
Brusselaers N, Ljung R, Mattsson F, Johar A, Wikman A, Lagergren P, et al
BMJ open 2013;3(12):e003754-

Initial experience with S-shaped electrode for continuous vagal nerve stimulation in thyroid surgery
Van Slycke S, Gillardin Jp, Brusselaers N, Vermeersch H
LANGENBECKS ARCHIVES OF SURGERY 2013;398(5):717-22

Keratinocytes in the treatment of severe burn injury: an update
Lootens L, Brusselaers N, Beele H, Monstrey S
INTERNATIONAL WOUND JOURNAL 2013;10(1):6-12

Value of lower respiratory tract surveillance cultures to predict bacterial pathogens in ventilator-associated pneumonia: systematic review and diagnostic test accuracy meta-analysis
Brusselaers N, Labeau S, Vogelaers D, Blot S
Intensive care medicine 2013;39(3):365-75

A Clinical Algorithm to Diagnose Invasive Pulmonary Aspergillosis in Critically Ill Patients
Aspicu Study Investigators, Blot Si, Taccone Fs, Van Den Abeele Am, Bulpa P, Meersseman W, et al
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 2012;186(1):56-64

Burns, inhalation injury and ventilator-associated pneumonia: Value of routine surveillance cultures
Brusselaers N, Logie D, Vogelaers D, Monstrey S, Blot S
BURNS 2012;38(3):364-70

Phototoxic reaction after parathyroid surgery: case report and review of the literature
Lambrecht P, Vandeplas G, Van Slycke S, Smet Pf, Brusselaers N, Vermeersch H
Acta clinica Belgica 2012;67(6):438-41

Outcome prediction in severe burn injury: clinical versus laboratory markers
Brusselaers N, Monstrey S, Vogelaers D, Blot S
European journal of trauma and emergency surgery : official publication of the European Trauma Society 2011;37(5):533-

Outcome prediction in severe burn injury: clinical versus laboratory markers
Brusselaers N, Monstrey S, Vogelaers D, Blot S
EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY 2011;37(5):533-534

Prevention of ventilator-associated pneumonia with oral antiseptics: a systematic review and meta-analysis
Labeau So, Van De Vyver K, Brusselaers N, Vogelaers D, Blot Si
LANCET INFECTIOUS DISEASES 2011;11(11):845-54

Risk factors and mortality for nosocomial bloodstream infections in elderly patients
Reunes S, Rombaut V, Vogelaers D, Brusselaers N, Lizy C, Cankurtaran M, et al
EUROPEAN JOURNAL OF INTERNAL MEDICINE 2011;22(5):e39-44

The rising problem of antimicrobial resistance in the intensive care unit
Brusselaers N, Vogelaers D, Blot S
Annals of intensive care 2011;1():47-

Web-based resources for critical care education. The EVIDENCE Crash Course: A Web-based interactive e-course on infection prevention for critical care clinicians
Labeau So, Vandijck Dm, Brusselaers N, Vandewoude K, Vogelaers Dp, Blot Si
CRITICAL CARE MEDICINE 2011;39(9):2202-3

Burn Scar Assessment: A Systematic Review of Different Scar Scales
Brusselaers N, Pirayesh A, Hoeksema H, Verbelen J, Blot S, Monstrey S
JOURNAL OF SURGICAL RESEARCH 2010;164(1):e115-23

Burn scar assessment: A systematic review of objective scar assessment tools
Brusselaers N, Pirayesh A, Hoeksema H, Verbelen J, Blot S, Monstrey S
BURNS 2010;36(8):1157-64

MORBIDITY AND MORTALITY OF BLOODSTREAM INFECTIONS IN PATIENTS WITH SEVERE BURN INJURY
Brusselaers N, Monstrey S, Snoeij T, Vandijck D, Lizy C, Hoste E, et al
AMERICAN JOURNAL OF CRITICAL CARE 2010;19(6):e81-7

Outcome of acute kidney injury in severe burns: a systematic review and meta-analysis
Brusselaers N, Monstrey S, Colpaert K, Decruyenaere J, Blot Si, Hoste Eaj
INTENSIVE CARE MEDICINE 2010;36(6):915-25

Predictive value of the Belgian Outcome in Burn Injury (BOBI) prediction model
Brusselaers N, Juhasz I, Erdei I, Monstrey S, Blot S
BURNS 2010;36(8):1318-1320

Severe burn injury in europe: a systematic review of the incidence, etiology, morbidity, and mortality
Brusselaers N, Monstrey S, Vogelaers D, Hoste E, Blot S
CRITICAL CARE 2010;14(5):R188-

Skin Replacement in Burn Wounds
Brusselaers N, Pirayesh A, Hoeksema H, Richters Cd, Verbelen J, Beele H, et al
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE 2010;68(2):490-501

Development and validation of a model for prediction of mortality in patients with acute burn injury
Belgian Outcome Burn Injury Stud, Blot S, Brusselaers N, Monstrey S, Vandewoude K, De Waele Jj, et al
BRITISH JOURNAL OF SURGERY 2009;96(1):111-7

Evaluation of mortality following severe burns injury in Hungary: External validation of a prediction model developed on Belgian burn data
Brusselaers N, Juhasz I, Erdei I, Monstrey S, Blot S
BURNS 2009;35(7):1009-14

Impact of a prevention strategy targeting hand hygiene and catheter care on the incidence of catheter-related bloodstream infections
Vandijck Dm, Labeau So, Brusselaers N, De Wandel D, Vogelaers Dp, Blot Si
CRITICAL CARE MEDICINE 2009;37(11):2998-9

Oral Care, Ventilator-Associated Pneumonia, and Counting Cultures
Lizy C, Brusselaers N, Labeau S, Vandijck D, De Wandel D, Vogelaers D, et al
AMERICAN JOURNAL OF CRITICAL CARE 2009;18(6):507-8

Reduction of ventilator-associated pneumonia: enhancing knowledge is important
Labeau So, Vandijck Dm, Brusselaers N, De Wandel D, Vogelaers Dp, Blot Si
INTENSIVE CARE MEDICINE 2009;35(10):1818-9

The FLAMES Score Accurately Predicts Mortality Risk in Burn Patients (Gomez M, et al. 2008)
Brusselaers N, Monstrey S, Blot S
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE 2009;67(2):415-

The FLAMES Score Accurately Predicts Mortality Risk in Burn Patients (vol 67, pg 415, 2008)
Brusselaers N, Monstrey S, Blot S
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE 2009;67(4):896-896

The Consensus of the Surgical Treatment of Burn Injuries in Belgium
Brusselaers N, Lafaire C, Ortiz S, Jacquemin D, Monstrey S
ACTA CHIRURGICA BELGICA 2008;108(6):645-50

Inflammatory markers in patients with severe burn injury: What is the best indicator of sepsis?
Vandijck Dm, Brusselaers N, Blot Si
BURNS 2007;33(7):939-40

Prediction of morbidity and mortality on admission to a burn unit
Brusselaers N, Monstrey Sj, Vandijck Dm, Blot Si
PLASTIC AND RECONSTRUCTIVE SURGERY 2007;120(1):360-1

Septicemia as a cause of death in burns
Vandijck Dm, Brusselaers N, Blot Si
BURNS 2007;33(4):538-9

Outcome and changes over time in survival following severe burns from 1985 to 2004
Brusselaers N, Hoste Eaj, Monstrey S, Colpaert Ke, De Waele Jj, Vandewoude Kh, et al
INTENSIVE CARE MEDICINE 2005;31(12):1648-53

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