Moustapha Hassan

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About me

Moustapha Hassan was appointed Professor of Transplantation Research at the Department of Laboratory Medicine in 2013. His research concerns improved survival and quality of life in cancer patients treated with chemotherapy and stem cell transplantation.

Articles

Article: TRANSPLANTATION AND CELLULAR THERAPY. 2023;29(9):581.e1-581.e8

Interaction Between High-Dose Intravenous Busulfan and Post-Transplantation Cyclophosphamide on Hemorrhagic Cystitis After Allogeneic Hematopoietic Cell Transplantation.

Santos Carreira A; Salas MQ; Remberger M; Novitzky-Basso I; Law AD; Lam W; Pasic I; Mazzulli T; Cserti-Gazdewich C; Kim DDH; Michelis FV; Viswabandya A; Gerbitz A; Lipton JH; Kumar R; Hassan M; Mattsson J
Article: CELL JOURNAL. 2023;25(8):524-535

Umbilical Cord Blood-Derived Monocytes as A Reliable Source of Functional Macrophages for Biomedical Research.

Torabi S; Zarrabi M; Hossein-Khannazer N; Lotfinia M; Nouri M; Gramignoli R; Hassan M; Vosough M
Article: NANO TODAY. 2023;50:101824

NIR light-driven photocatalytic NAD(P)H oxidation and H2O2 generation in situ for enhanced chemodynamic therapy and immune response

Zhang C; Huang J; Guo X; Da X; Dai Z; Hassan M; Yu Y; Wang X; Zhou Q
Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2023;11(2):e005691

Tuned activation of MSLN-CAR T cells induces superior antitumor responses in ovarian cancer models.

Schoutrop E; Poiret T; El-Serafi I; Zhao Y; He R; Moter A; Henriksson J; Hassan M; Magalhaes I; Mattsson J
Article: PHYTOMEDICINE. 2023;110:154634

Celastrol targets the ChREBP-TXNIP axis to ameliorates type 2 diabetes mellitus.

Zhou D; Li X; Xiao X; Wang G; Chen B; Song Y; Liu X; He Q; Zhang H; Wu Q; Zhang L; Wu L; Shen Z; Hassan M; Zhao Y; Zhou W
Article: MOLECULAR AND CELLULAR BIOCHEMISTRY. 2023;478(1):23-37

Novel antigens for targeted radioimmunotherapy in hepatocellular carcinoma.

Pourhamzeh M; Asadian S; Mirzaei H; Minaei A; Shahriari E; Shpichka A; Es HA; Timashev P; Hassan M; Vosough M
Article: JOURNAL OF BIOMEDICAL NANOTECHNOLOGY. 2023;19(1):28-35

Perfluorocarbon-Encapsulated Porphyrin-Lipid Nanoparticles as a Photoactive Pyroptosis Inducer for Cancer Therapy

Lin X; Jiang X; Xu Y; Liu R; Zhang N; Li R; Xiang H; Zhao C; Zhao Z; Zeng W; Qu S; Tan X; Cheng C; Chen X; Wang M; Liu Y; Liu L; Zhao Y; Dai Z; Hassan M; Sun D
Article: STEM CELLS INTERNATIONAL. 2022;2022:1850305-14

Conjugated Linoleic Acid Treatment Attenuates Cancerous features in Hepatocellular Carcinoma Cells.

Miri-Lavasani Z; Torabi S; Solhi R; Shokouhian B; Afsharian P; Heydari Z; Piryaei A; Farzaneh Z; Hossein-Khannazer N; Es HA; Zahmatkesh E; Nussler A; Hassan M; Najimi M; Vosough M
Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2022;106:108587

Novel insights in CAR-NK cells beyond CAR-T cell technology; promising advantages.

Ebrahimiyan H; Tamimi A; Shokoohian B; Minaei N; Memarnejadian A; Hossein-Khannazer N; Hassan M; Vosough M
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2022;28(4):196-202

Association Between the Magnitude of Intravenous Busulfan Exposure and Development of Hepatic Veno-Occlusive Disease in Children and Young Adults Undergoing Myeloablative Allogeneic Hematopoietic Cell Transplantation.

Bognàr T; Bartelink IH; Egberts TCG; Rademaker CMA; Versluys AB; Slatter MA; Kletzel M; Nath CE; Cuvelier GDE; Savic RM; Dvorak C; Long-Boyle JR; Cowan MJ; Bittencourt H; Bredius RGM; Güngör T; Shaw PJ; Ansari M; Hassan M; Krajinovic M; Hempel G; Marktel S; Chiesa R; Théoret Y; Lund T; Orchard PJ; Wynn RF; Boelens JJ; Lalmohamed A
Article: BMJ GLOBAL HEALTH. 2022;7(4):e008143

Derivation and validation of a novel risk assessment tool to identify children aged 2-59 months at risk of hospitalised pneumonia-related mortality in 20 countries.

Rees CA; Colbourn T; Hooli S; King C; Lufesi N; McCollum ED; Mwansambo C; Cutland C; Madhi SA; Nunes M; Matthew JL; Addo-Yobo E; Chisaka N; Hassan M; Hibberd PL; Jeena PM; Lozano JM; MacLeod WB; Patel A; Thea DM; Nguyen NTV; Kartasasmita CB; Lucero M; Awasthi S; Bavdekar A; Chou M; Nymadawa P; Pape J-W; Paranhos-Baccala G; Picot VS; Rakoto-Andrianarivelo M; Rouzier V; Russomando G; Sylla M; Vanhems P; Wang J; Asghar R; Banajeh S; Iqbal I; Maulen-Radovan I; Mino-Leon G; Saha SK; Santosham M; Singhi S; Basnet S; Strand TA; Bhatnagar S; Wadhwa N; Lodha R; Aneja S; Clara AW; Campbell H; Nair H; Falconer J; Qazi SA; Nisar YB; Neuman MI; World Health Organization PREPARE study group
Article: CELLS. 2022;11(2):305

Rhenium Perrhenate (188ReO4) Induced Apoptosis and Reduced Cancerous Phenotype in Liver Cancer Cells.

Asadian S; Piryaei A; Gheibi N; Aziz Kalantari B; Reza Davarpanah M; Azad M; Kapustina V; Alikhani M; Moghbeli Nejad S; Keshavarz Alikhani H; Mohamadi M; Shpichka A; Timashev P; Hassan M; Vosough M
Article: NPJ BREAST CANCER. 2022;8(1):2

Endoplasmic reticulum stress inhibits AR expression via the PERK/eIF2α/ATF4 pathway in luminal androgen receptor triple-negative breast cancer and prostate cancer.

Li X; Zhou D; Cai Y; Yu X; Zheng X; Chen B; Li W; Zeng H; Hassan M; Zhao Y; Zhou W
Article: JOURNAL OF PERSONALIZED MEDICINE. 2022;12(1):42

COL-3-Induced Molecular and Ultrastructural Alterations in K562 Cells.

Fares M; Oerther S; Hultenby K; Gubrianska D; Zhao Y; Abedi-Valugerdi M; Hassan M
Article: CANCER RESEARCH. 2021;81(11):3022-3035

Mesothelin-Specific CAR T Cells Target Ovarian Cancer.

Schoutrop E; El-Serafi I; Poiret T; Zhao Y; Gultekin O; He R; Moyano-Galceran L; Carlson JW; Lehti K; Hassan M; Magalhaes I; Mattsson J
Article: INTERNATIONAL JOURNAL OF PHARMACEUTICS. 2021;601:120588

Biodistribution of fluorescence-labelled EGF protein from slow release NanoZolid depots in mouse.

Grudén S; Brunmark C; Holmqvist B; Brenndörfer ED; Johansson M; Liu J; Zhao Y; Axén N; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2021;56(4):807-817

Vitamin D levels and busulphan kinetics in patients undergoing hematopoietic stem cell transplantation, a multicenter study.

El-Serafi A; He R; Zheng W; Benkossou F; Oerther S; Zhao Y; Mellgren K; Gustafsson B; Heilmann C; Kanerva J; Lotfi K; Toporski J; Sundin M; Höglund M; Mattsson J; El-Serafi I; Hassan M
Article: SCIENTIFIC REPORTS. 2021;11(1):2707

Cyclophosphamide exposure assessed with the biomarker phosphoramide mustard-hemoglobin in breast cancer patients: The TailorDose I study.

Gernaat SAM; von Stedingk H; Hassan M; Nilsson HP; Rodriguez-Wallberg KA; Hedayati E; Rydberg P
Article: ACS APPLIED MATERIALS & INTERFACES. 2020;12(48):53665-53681

Multimodal Imaging of Pancreatic Ductal Adenocarcinoma Using Multifunctional Nanoparticles as Contrast Agents.

Zhao Y; Ye F; Brismar TB; Li X; He R; Heuchel R; El-Sayed R; Feliu N; Zheng W; Oerther S; Dutta J; Parak WJ; Muhammed M; Hassan M
Article: PHARMACOLOGICAL RESEARCH. 2020;160:105070

β-radiating radionuclides in cancer treatment, novel insight into promising approach.

Asadian S; Mirzaei H; Kalantari BA; Davarpanah MR; Mohamadi M; Shpichka A; Nasehi L; Es HA; Timashev P; Najimi M; Gheibi N; Hassan M; Vosough M
Article: BLOOD ADVANCES. 2020;4(9):1998-2010

Targeted busulfan-based reduced-intensity conditioning and HLA-matched HSCT cure hemophagocytic lymphohistiocytosis.

Felber M; Steward CG; Kentouche K; Fasth A; Wynn RF; Zeilhofer U; Haunerdinger V; Volkmer B; Prader S; Gruhn B; Ehl S; Lehmberg K; Müller D; Gennery AR; Albert MH; Hauck F; Rao K; Veys P; Hassan M; Lankester AC; Schmid JP; Hauri-Hohl MM; Güngör T
Article: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 2020;143:105158

Pharmacokinetic profile of N-acetylcysteine amide and its main metabolite in mice using new analytical method.

He R; Zheng W; Ginman T; Ottosson H; Norgren S; Zhao Y; Hassan M
Article: SCIENTIFIC REPORTS. 2020;10(1):1274

A general covalent binding model between cytotoxic selenocompounds and albumin revealed by mass spectrometry and X-ray absorption spectroscopy.

Zheng W; He R; Boada R; Subirana MA; Ginman T; Ottosson H; Valiente M; Zhao Y; Hassan M
Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2020;78:106042

The kidney injury caused by the onset of acute graft-versus-host disease is associated with down-regulation of αKlotho.

Amin R; He R; Gupta D; Zheng W; Burmakin M; Mohammad DK; DePierre JW; Sadeghi B; Olauson H; Wernerson A; El-Andaloussi S; Hassan M; Abedi-Valugerdi M
Article: FRONTIERS IN PHARMACOLOGY. 2020;11:406

Population Pharmacokinetic, Pharmacogenetic, and Pharmacodynamic Analysis of Cyclophosphamide in Ethiopian Breast Cancer Patients.

Ahmed JH; Makonnen E; Bisaso RK; Mukonzo JK; Fotoohi A; Aseffa A; Howe R; Hassan M; Aklillu E
Article: CLINICAL TRANSPLANTATION. 2019;33(12):e13742

Bone and hormonal status 10 years post-allogeneic bone marrow transplantation.

Gubrianska D; Machaczka M; Hassan M; Hägglund H; Ljungman P; Palmér M
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2019;20(19):E4734-4734

Extracellular Albumin Covalently Sequesters Selenocompounds and Determines Cytotoxicity.

Zheng W; Boada R; He R; Xiao T; Ye F; Simonelli L; Valiente M; Zhao Y; Hassan M
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2019;25(9):1890-1897

Harmonization of Busulfan Plasma Exposure Unit (BPEU): A Community-Initiated Consensus Statement.

McCune JS; Quinones CM; Ritchie J; Carpenter PA; van Maarseveen E; Yeh RF; Anasetti C; Boelens JJ; Hamerschlak N; Hassan M; Kang HJ; Kanda Y; Paci A; Perales M-A; Shaw PJ; Seewaldt VL; Savani BN; Hsieh A; Poon B; Mohty M; Pulsipher MA; Pasquini M; Dupuis LL
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2019;515(3):487-492

Degradation of pristine and oxidized single wall carbon nanotubes by CYP3A4.

El-Sayed R; Waraky A; Ezzat K; Albabtain R; ElGammal K; Shityakov S; Muhammed M; Hassan M
Article: BEHAVIOURAL BRAIN RESEARCH. 2019;367:28-34

Sustained overexpression of neuropeptide S in the amygdala reduces anxiety-like behavior in rats.

Tillmann S; Skibdal HE; Christiansen SH; Gøtzsche CR; Hassan M; Mathé AA; Wegener G; Woldbye DPD
Article: APPLIED MATERIALS TODAY. 2019;15:267-279

Tracking stem cells and macrophages with gold and iron oxide nanoparticles - The choice of the best suited particles

Sun X; Gamal M; Nold P; Said A; Chakraborty I; Pelaz B; Schmied F; von Pueckler K; Figiel J; Zhao Y; Brendel C; Hassan M; Parak WJ; Feliu N
Article: SCIENTIFIC REPORTS. 2019;9(1):3903

CT Scanning and MATLAB Calculations for Preservation of Coptic Mural Paintings in Historic Egyptian Monasteries.

Sallam A; Hemeda S; Toprak MS; Muhammed M; Hassan M; Uheida A
Article: FRONTIERS IN PHARMACOLOGY. 2019;10:481

CYP2J2∗7 Genotype Predicts Risk of Chemotherapy-Induced Hematologic Toxicity and Reduced Relative Dose Intensity in Ethiopian Breast Cancer Patients.

Ahmed JH; Makonnen E; Yimer G; Seifu D; Bekele A; Assefa M; Aseffa A; Howe R; Fotoohi A; Hassan M; Aklillu E
Article: BEHAVIOURAL BRAIN RESEARCH. 2018;351:93-103

Sex-dependent behavior, neuropeptide profile and antidepressant response in rat model of depression.

Sanchez C; El Khoury A; Hassan M; Wegener G; Mathé AA
Article: ASIAN PACIFIC JOURNAL OF CANCER PREVENTION. 2018;19(8):2305-2311

miR-1266-5p and miR-185-5p Promote Cell Apoptosis in Human Prostate Cancer Cell Lines.

Ostadrahimi S; Abedi Valugerdi M; Hassan M; Haddad G; Fayaz S; Parvizhamidi M; Mahdian R; Fard Esfahani P
Article: JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY. 2018;46:482-489

Cold isostatic pressing of hydrating calcium sulfate as a means to produce parenteral slow-release drug formulations

Gruden S; Hassan M; Axen N
Article: SCIENTIFIC REPORTS. 2018;8(1):8293

The effect of N-acetyl-l-cysteine (NAC) on liver toxicity and clinical outcome after hematopoietic stem cell transplantation.

El-Serafi I; Remberger M; El-Serafi A; Benkessou F; Zheng W; Martell E; Ljungman P; Mattsson J; Hassan M
Article: ONCOLOGY LETTERS. 2018;15(5):8157-8164

Downregulation of miR-1266-5P, miR-185-5P and miR-30c-2 in prostatic cancer tissue and cell lines.

Ostadrahimi S; Fayaz S; Parvizhamidi M; Abedi-Valugerdi M; Hassan M; Kadivar M; Teimoori-Toolabi L; Asgari M; Shahrokh H; Abolhasani M; Mahdian R; Fard-Esfahani P
Article: JOURNAL OF THEORETICAL BIOLOGY. 2018;442:1-10

Mathematical modeling of tumor-induced immunosuppression by myeloid-derived suppressor cells: Implications for therapeutic targeting strategies.

Shariatpanahi SP; Shariatpanahi SP; Madjidzadeh K; Hassan M; Abedi-Valugerdi M
Article: NANO TODAY. 2018;18:103-123

Advances in nanotechnology for cancer biomarkers

Ye F; Zhao Y; Ei-Sayed R; Muhammed M; Hassan M
Article: JOURNAL OF CLINICAL APHERESIS. 2017;32(6):384-391

G-CSF mobilized peripheral blood stem cell collection for allogeneic transplantation in healthy donors: Analysis of factors affecting yield.

Machaczka M; Hägglund H; Staver E; Joks M; Hassan M; Wahlin BE; Axdorph Nygell U
Article: INTERNATIONAL JOURNAL OF HEMATOLOGY. 2017;106(4):471-475

Toxicological effects of fludarabine and treosulfan conditioning before allogeneic stem-cell transplantation.

Remberger M; Törlen J; Serafi IE; Garming-Legert K; Björklund A; Ljungman P; Sundin M; Hassan M; Mattsson J
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2017;491(1):15-18

Importance of the surface chemistry of nanoparticles on peroxidase-like activity.

El-Sayed R; Ye F; Asem H; Ashour R; Zheng W; Muhammed M; Hassan M
Article: EXPERIMENTAL HEMATOLOGY. 2017;52:65-71

Development of an assay for cellular efflux of pharmaceutically active agents and its relevance to understanding drug interactions.

Valdez BC; Hassan M; Andersson BS
Article: ANALYTICAL CHEMISTRY. 2017;89(14):7586-7592

Rapid and Robust Quantification of p-Xyleneselenocyanate in Plasma via Derivatization.

Zheng W; Benkessou F; Twelkmeyer B; Wang S; Ginman T; Ottosson H; Abedi-Valugerdi M; Subirana MA; Zhao Y; Hassan M
Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2017;47:173-181

Differential effects of low-dose fludarabine or 5-fluorouracil on the tumor growth and myeloid derived immunosuppression status of tumor-bearing mice.

Abedi-Valugerdi M; Zheng W; Benkessou F; Zhao Y; Hassan M
Article: PLOS ONE. 2017;12(11):e0187294

Flavin-containing monooxygenase 3 (FMO3) role in busulphan metabolic pathway.

El-Serafi I; Terelius Y; Abedi-Valugerdi M; Naughton S; Saghafian M; Moshfegh A; Mattsson J; Potácová Z; Hassan M
Article: JOURNAL OF NANOBIOTECHNOLOGY. 2016;14(1):82

Biodistribution of biodegradable polymeric nano-carriers loaded with busulphan and designed for multimodal imaging.

Asem H; Zhao Y; Ye F; Barrefelt Å; Abedi-Valugerdi M; El-Sayed R; El-Serafi I; Abu-Salah KM; Hamm J; Muhammed M; Hassan M
Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2016;40:41-49

Suppressive effects of low-dose 5-fluorouracil, busulfan or treosulfan on the expansion of circulatory neutrophils and myeloid derived immunosuppressor cells in tumor-bearing mice.

Abedi-Valugerdi M; Wolfsberger J; Pillai PR; Zheng W; Sadeghi B; Zhao Y; Hassan M
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2016;22(11):1915-1925

Personalizing Busulfan-Based Conditioning: Considerations from the American Society for Blood and Marrow Transplantation Practice Guidelines Committee.

Palmer J; McCune JS; Perales M-A; Marks D; Bubalo J; Mohty M; Wingard JR; Paci A; Hassan M; Bredeson C; Pidala J; Shah N; Shaughnessy P; Majhail N; Schriber J; Savani BN; Carpenter PA
Article: LANCET HAEMATOLOGY. 2016;3(11):e526-e536

Association of busulfan exposure with survival and toxicity after haemopoietic cell transplantation in children and young adults: a multicentre, retrospective cohort analysis.

Bartelink IH; Lalmohamed A; van Reij EML; Dvorak CC; Savic RM; Zwaveling J; Bredius RGM; Egberts ACG; Bierings M; Kletzel M; Shaw PJ; Nath CE; Hempel G; Ansari M; Krajinovic M; Théorêt Y; Duval M; Keizer RJ; Bittencourt H; Hassan M; Güngör T; Wynn RF; Veys P; Cuvelier GDE; Marktel S; Chiesa R; Cowan MJ; Slatter MA; Stricherz MK; Jennissen C; Long-Boyle JR; Boelens JJ
Article: PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY. 2016;13:48-57

Development and biodistribution of a theranostic aluminum phthalocyanine nanophotosensitizer.

Asem H; El-Fattah AA; Nafee N; Zhao Y; Khalil L; Muhammed M; Hassan M; Kandil S
Article: PHARMACOGENOMICS JOURNAL. 2015;15(5):405-413

Cytochrome P450 2J2, a new key enzyme in cyclophosphamide bioactivation and a potential biomarker for hematological malignancies.

El-Serafi I; Fares M; Abedi-Valugerdi M; Afsharian P; Moshfegh A; Terelius Y; Potácová Z; Hassan M
Article: CELL METABOLISM. 2015;22(3):408-417

Transplanted Bone Marrow-Derived Cells Contribute to Human Adipogenesis.

Rydén M; Uzunel M; Hård JL; Borgström E; Mold JE; Arner E; Mejhert N; Andersson DP; Widlund Y; Hassan M; Jones CV; Spalding KL; Svahn B-M; Ahmadian A; Frisén J; Bernard S; Mattsson J; Arner P
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2015;464(3):737-742

Fluorescence labeled microbubbles for multimodal imaging.

Barrefelt Å; Zhao Y; Larsson MK; Egri G; Kuiper RV; Hamm J; Saghafian M; Caidahl K; Brismar TB; Aspelin P; Heuchel R; Muhammed M; Dähne L; Hassan M
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2015;463(3):268-274

DNA damage, lysosomal degradation and Bcl-xL deamidation in doxycycline- and minocycline-induced cell death in the K562 leukemic cell line.

Fares M; Abedi-Valugerdi M; Hassan M; Potácová Z
Article: CHEMOSPHERE. 2015;129:225-231

Complement activation is involved in the hepatic injury caused by high-dose exposure of mice to perfluorooctanoic acid.

Botelho SC; Saghafian M; Pavlova S; Hassan M; DePierre JW; Abedi-Valugerdi M
Article: CHRONOBIOLOGY INTERNATIONAL. 2015;32(5):608-614

The effect of circadian rhythm on pharmacokinetics and metabolism of the Cdk inhibitor, roscovitine, in tumor mice model.

Sallam H; El-Serafi AT; Filipski E; Terelius Y; Lévi F; Hassan M
Article: IMMUNOLOGY LETTERS. 2015;163(2):193-198

Immunotoxicological effects of streptozotocin and alloxan: in vitro and in vivo studies.

Diab RAH; Fares M; Abedi-Valugerdi M; Kumagai-Braesch M; Holgersson J; Hassan M
Article: PLOS ONE. 2015;10(11):e0141979

Cytochrome P450 Oxidoreductase Influences CYP2B6 Activity in Cyclophosphamide Bioactivation.

El-Serafi I; Afsharian P; Moshfegh A; Hassan M; Terelius Y
Article: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2014;58(8):4941-4943

Posaconazole concentrations in human tissues after allogeneic stem cell transplantation.

Blennow O; Eliasson E; Pettersson T; Pohanka A; Szakos A; El-Serafi I; Hassan M; Ringdén O; Mattsson J
Article: NANO. 2014;9(6):1450069

DYNAMIC MR IMAGING, BIODISTRIBUTION AND PHARMACOKINETICS OF POLYMER SHELLED MICROBUBBLES CONTAINING SPION

Barrefelt A; Paradossi G; Asem H; Margheritelli S; Saghafian M; Oddo L; Muhammed M; Aspelin P; Hassan M; Brismar TB
Article: LEUKEMIA & LYMPHOMA. 2014;55(7):1618-1624

The nanoparticulate Quillaja saponin KGI exerts anti-proliferative effects by down-regulation of cell cycle molecules in U937 and HL-60 human leukemia cells.

Berenjian S; Hu K; Abedi-Valugerdi M; Hassan M; Bashir Hassan S; Morein B
Article: XENOTRANSPLANTATION. 2014;21(4):353-366

Rat islets are not rejected by anti-islet antibodies in mice treated with costimulation blockade.

Diab RAH; Hassan M; Tibell A; Holgersson J; Kumagai-Braesch M
Article: BIOMATERIALS. 2014;35(12):3885-3894

Biodegradable polymeric vesicles containing magnetic nanoparticles, quantum dots and anticancer drugs for drug delivery and imaging.

Ye F; Barrefelt A; Asem H; Abedi-Valugerdi M; El-Serafi I; Saghafian M; Abu-Salah K; Alrokayan S; Muhammed M; Hassan M
Article: LANCET. 2014;383(9915):436-448

Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study.

Güngör T; Teira P; Slatter M; Stussi G; Stepensky P; Moshous D; Vermont C; Ahmad I; Shaw PJ; Telles da Cunha JM; Schlegel PG; Hough R; Fasth A; Kentouche K; Gruhn B; Fernandes JF; Lachance S; Bredius R; Resnick IB; Belohradsky BH; Gennery A; Fischer A; Gaspar HB; Schanz U; Seger R; Rentsch K; Veys P; Haddad E; Albert MH; Hassan M; Inborn Errors Working Party of the European Societ
Article: CLINICAL DRUG INVESTIGATION. 2014;34(1):43-52

Comparison of algorithms for oral busulphan area under the concentration-time curve limited sampling estimate.

Sjöö F; El-Serafi I; Enestig J; Mattsson J; Liwing J; Hassan M
Article: PLOS ONE. 2014;9(1):e86619

Cyclophosphamide alters the gene expression profile in patients treated with high doses prior to stem cell transplantation.

El-Serafi I; Abedi-Valugerdi M; Potácová Z; Afsharian P; Mattsson J; Moshfegh A; Hassan M
Article: THERANOSTICS. 2014;4(6):604-613

Real-time assessment of tissue hypoxia in vivo with combined photoacoustics and high-frequency ultrasound.

Gerling M; Zhao Y; Nania S; Norberg KJ; Verbeke CS; Englert B; Kuiper RV; Bergström A; Hassan M; Neesse A; Löhr JM; Heuchel RL
Article: BMC PHARMACOLOGY & TOXICOLOGY. 2013;14:50

Pharmacokinetics and biodistribution of the cyclin-dependent kinase inhibitor -CR8- in mice.

Sallam H; El-Serafi I; Meijer L; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2013;48(6):843-848

Omega-3 from fish oil augments GVHD through the enhancement of chemotherapy conditioning regimen and selective FoxP3 depletion.

Al Hashmi S; Sadeghi B; Hassan Z; Abedi-Valugerdi M; Lindskog M; Hassan M
Article: TOXICOLOGY LETTERS. 2013;219(1):1-7

Sub-acute, moderate-dose, but not short-term, low-dose dietary pre-exposure of mice to perfluorooctanoate aggravates concanavalin A-induced hepatitis.

Qazi MR; Hassan M; Nelson BD; Depierre JW; Abedi-Valugerdi M
Article: PEDIATRIC TRANSPLANTATION. 2013;17(3):285-293

Increased risk of gastrointestinal acute GVHD following the addition of melphalan to busulfan/cyclophosphamide conditioning.

Mårtensson T; Priftakis P; Casswall T; Ringdén O; Mattsson J; Remberger M; Hassan M; Gustafsson B
Article: NANO LETTERS. 2013;13(4):1393-1398

Thermostable luciferase from Luciola cruciate for imaging of carbon nanotubes and carbon nanotubes carrying doxorubicin using in vivo imaging system.

El-Sayed R; Eita M; Barrefelt A; Ye F; Jain H; Fares M; Lundin A; Crona M; Abu-Salah K; Muhammed M; Hassan M
Article: EJNMMI RESEARCH. 2013;3(1):12

Multimodality imaging using SPECT/CT and MRI and ligand functionalized 99mTc-labeled magnetic microbubbles.

Barrefelt AA; Brismar TB; Egri G; Aspelin P; Olsson A; Oddo L; Margheritelli S; Caidahl K; Paradossi G; Dähne L; Axelsson R; Hassan M
Article: TOXICOLOGY LETTERS. 2013;217(1):67-74

Both sub-acute, moderate-dose and short-term, low-dose dietary exposure of mice to perfluorooctane sulfonate exacerbates concanavalin A-induced hepatitis.

Qazi MR; Hassan M; Nelson BD; DePierre JW; Abedi-Valugerdi M
Article: BONE MARROW TRANSPLANTATION. 2013;48(2):284-293

Early-phase GVHD gene expression profile in target versus non-target tissues: kidney, a possible target?

Sadeghi B; Al-Chaqmaqchi H; Al-Hashmi S; Brodin D; Hassan Z; Abedi-Valugerdi M; Moshfegh A; Hassan M
Article: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2013;913-914:98-105

Gas chromatographic-mass spectrometry method for the detection of busulphan and its metabolites in plasma and urine.

El-Serafi I; Terelius Y; Twelkmeyer B; Hagbjörk A-L; Hassan Z; Hassan M
Article: PLOS ONE. 2013;8(4):e60367

The role of programmed cell death ligand-1 (PD-L1/CD274) in the development of graft versus host disease.

Al-Chaqmaqchi H; Sadeghi B; Abedi-Valugerdi M; Al-Hashmi S; Fares M; Kuiper R; Lundahl J; Hassan M; Moshfegh A
Article: PLOS ONE. 2013;8(7):e68937

Activation of Wnt/β-catenin pathway in monocytes derived from chronic kidney disease patients.

Al-Chaqmaqchi HAM; Moshfegh A; Dadfar E; Paulsson J; Hassan M; Jacobson SH; Lundahl J
Article: INTERNATIONAL JOURNAL OF NANOMEDICINE. 2013;8:3241-3254

Biodistribution, kinetics, and biological fate of SPION microbubbles in the rat.

Barrefelt Å; Saghafian M; Kuiper R; Ye F; Egri G; Klickermann M; Brismar TB; Aspelin P; Muhammed M; Dähne L; Hassan M
Article: PLOS ONE. 2012;7(1):e30897

Busulphan-cyclophosphamide cause endothelial injury, remodeling of resistance arteries and enhanced expression of endothelial nitric oxide synthase.

Al-Hashmi S; Boels PJM; Zadjali F; Sadeghi B; Sällström J; Hultenby K; Hassan Z; Arner A; Hassan M
Article: NATURE MEDICINE. 2011;17(12):1636-1640

Inhibition of proteasome deubiquitinating activity as a new cancer therapy.

D'Arcy P; Brnjic S; Olofsson MH; Fryknäs M; Lindsten K; De Cesare M; Perego P; Sadeghi B; Hassan M; Larsson R; Linder S
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2011;17(11):1688-1697

Improved survival after allogeneic hematopoietic stem cell transplantation in recent years. A single-center study.

Remberger M; Ackefors M; Berglund S; Blennow O; Dahllöf G; Dlugosz A; Garming-Legert K; Gertow J; Gustafsson B; Hassan M; Hassan Z; Hauzenberger D; Hägglund H; Karlsson H; Klingspor L; Kumlien G; Le Blanc K; Ljungman P; Machaczka M; Malmberg K-J; Marschall H-U; Mattsson J; Olsson R; Omazic B; Sairafi D; Schaffer M; Svahn B-M; Svenberg P; Swartling L; Szakos A; Uhlin M; Uzunel M; Watz E; Wernerson A; Wikman A; Wikström A-C; Winiarski J; Ringdén O
Article: ORAL DISEASES. 2011;17(7):670-676

Long-term salivary function after conditioning with busulfan, fractionated or single-dose TBI.

Garming-Legert K; Remberger M; Ringdén O; Hassan M; Dahllöf G
Article: PEDIATRIC TRANSPLANTATION. 2011;15(6):580-588

Therapeutic drug monitoring is essential for intravenous busulfan therapy in pediatric hematopoietic stem cell recipients.

Malär R; Sjöö F; Rentsch K; Hassan M; Güngör T
Article: INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY. 2011;4(6):596-605

Dynamics of early histopathological changes in GVHD after busulphan/cyclophosphamide conditioning regimen.

Al-Hashmi S; Hassan Z; Sadeghi B; Rozell B; Hassan M
Article: SULTAN QABOOS UNIVERSITY MEDICAL JOURNAL. 2011;11(2):165-178

The Role of Pharmacokinetics and Pharmacodynamics in Early Drug Development with reference to the Cyclin-dependent Kinase (Cdk) Inhibitor - Roscovitine.

Hassan M; Sallam H; Hassan Z
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2011;41(4):1143-1153

N-acetyl-L-cysteine increases acute graft-versus-host disease and promotes T-cell-mediated immunity in vitro.

Karlsson H; Nava S; Remberger M; Hassan Z; Hassan M; Ringdén O
Article: CLINICAL AND DEVELOPMENTAL IMMUNOLOGY. 2010;2010:142943-13

Expansion and activation kinetics of immune cells during early phase of GVHD in mouse model based on chemotherapy conditioning.

Sadeghi B; Al-Hashmi S; Hassan Z; Rozell B; Concha H; Lundmark C; Grönvik K-O; Abedi-Valugerdi M; Hassan M
Article: CHRONOBIOLOGY INTERNATIONAL. 2009;26(8):1613-1621

Circadian variability of bilirubin in healthy men during normal sleep and after an acute shift of sleep.

Larsson A; Hassan M; Ridefelt P; Axelsson J
Article: CHRONOBIOLOGY INTERNATIONAL. 2009;26(6):1169-1188

Liver circadian clock, a pharmacologic target of cyclin-dependent kinase inhibitor seliciclib.

Iurisci I; Filipski E; Sallam H; Harper F; Guettier C; Maire I; Hassan M; Iacobelli S; Lévi F
Article: BONE MARROW TRANSPLANTATION. 2008;42(12):807-818

GVHD after chemotherapy conditioning in allogeneic transplanted mice.

Sadeghi B; Aghdami N; Hassan Z; Forouzanfar M; Rozell B; Abedi-Valugerdi M; Hassan M
Article: MOLECULAR CANCER THERAPEUTICS. 2008;7(9):2713-2724

N-&-N, a new class of cell death-inducing kinase inhibitors derived from the purine roscovitine.

Bettayeb K; Sallam H; Ferandin Y; Popowycz F; Fournet G; Hassan M; Echalier A; Bernard P; Endicott J; Joseph B; Meijer L
Article: TRANSPLANTATION. 2008;86(2):257-263

Evaluation of immune responses to seasonal influenza vaccination in healthy volunteers and in patients after stem cell transplantation.

Avetisyan G; Aschan J; Hassan M; Ljungman P
Article: PHARMACOLOGICAL RESEARCH. 2008;58(1):32-37

Age-dependent pharmacokinetics and effect of roscovitine on Cdk5 and Erk1/2 in the rat brain.

Sallam H; Jimenez P; Song H; Vita M; Cedazo-Minguez A; Hassan M
Article: NATURE. 2008;453(7196):783-787

Dynamics of fat cell turnover in humans.

Spalding KL; Arner E; Westermark PO; Bernard S; Buchholz BA; Bergmann O; Blomqvist L; Hoffstedt J; Näslund E; Britton T; Concha H; Hassan M; Rydén M; Frisén J; Arner P
Article: BONE MARROW TRANSPLANTATION. 2008;41(10):895-904

The effect of administration order of BU and CY on engraftment and toxicity in HSCT mouse model.

Sadeghi B; Jansson M; Hassan Z; Mints M; Hägglund H; Abedi-Valugerdi M; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2008;41(9):785-790

A prospective randomized study using N-acetyl-L-cysteine for early liver toxicity after allogeneic hematopoietic stem cell transplantation.

Barkholt L; Remberger M; Hassan Z; Fransson K; Omazic B; Svahn B-M; Karlsson H; Brune M; Hassan M; Mattsson J; Ringdén O
Article: BONE MARROW TRANSPLANTATION. 2008;41(7):621-625

Safe administration of oral BU twice daily during conditioning for stem cell transplantation in a paediatric population: a comparative study between the standard 4-dose and a 2-dose regimen.

Mellgren K; Nilsson C; Fasth A; Abrahamsson J; Winiarski J; Ringdén O; Hassan M
Article: JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES. 2008;31(5):683-694

Rapid and sensitive method for determination of cyclophosphamide in patients plasma samples utilizing microextraction by packed sorbent online with liquid chromatography-tandem mass spectrometry (MEPS-LC-MS/MS)

Said R; Hassan Z; Hassan M; Abdel-Rehim M
Article: EXPERIMENTAL HEMATOLOGY. 2008;36(2):149-157

Hypomethylation and apoptosis in 5-azacytidine-treated myeloid cells.

Khan R; Schmidt-Mende J; Karimi M; Gogvadze V; Hassan M; Ekström TJ; Zhivotovsky B; Hellström-Lindberg E
Article: HUMAN REPRODUCTION. 2008;23(1):139-143

Endometrial endothelial cells are derived from donor stem cells in a bone marrow transplant recipient.

Mints M; Jansson M; Sadeghi B; Westgren M; Uzunel M; Hassan M; Palmblad J
Article: THERAPEUTIC DRUG MONITORING. 2007;29(5):626-631

Higher plasma but not intracellular concentrations after infusion with liposomal daunorubicin compared with conventional daunorubicin in adult acute myeloid leukemia.

Löfgren C; Lehmann S; Jönsson-Videsäter K; Möllgård L; Linder O; Tidefelt U; Hassan M; Paul C
Article: JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES. 2007;30(20):3029-3041

Simultaneous determination of busulphan in plasma samples by liquid chromatography-electrospray ionization mass spectrometry utilizing microextraction in packed syringe (MEPS) as on-line sample preparation method

Abdel-Rehim M; Hassan Z; Skansem P; Hassan M
Article: CLINICAL CANCER RESEARCH. 2007;13(14):4218-4224

The effect of repeated administration of cyclophosphamide on cytochrome P450 2B in rats.

Afsharian P; Terelius Y; Hassan Z; Nilsson C; Lundgren S; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2006;38(10):687-692

Impact on the cytomegalovirus (CMV) viral load by CMV-specific T-cell immunity in recipients of allogeneic stem cell transplantation.

Avetisyan G; Larsson K; Aschan J; Nilsson C; Hassan M; Ljungman P
Article: NATURE MEDICINE. 2006;12(4):401-409

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

Ott MG; Schmidt M; Schwarzwaelder K; Stein S; Siler U; Koehl U; Glimm H; Kühlcke K; Schilz A; Kunkel H; Naundorf S; Brinkmann A; Deichmann A; Fischer M; Ball C; Pilz I; Dunbar C; Du Y; Jenkins NA; Copeland NG; Lüthi U; Hassan M; Thrasher AJ; Hoelzer D; von Kalle C; Seger R; Grez M
Article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2006;98(2):197-200

Inhibitory effect of 5-fluorouracil on cytochrome P450 2C9 activity in cancer patients.

Gunes A; Coskun U; Boruban C; Gunel N; Babaoglu MO; Sencan O; Bozkurt A; Rane A; Hassan M; Zengil H; Yasar U
Article: EXPERIMENTAL HEMATOLOGY. 2006;34(1):115-121

Myeloablative and immunosuppressive properties of treosulfan in mice.

Sjöö F; Hassan Z; Abedi-Valugerdi M; Griskevicius L; Nilsson C; Remberger M; Aschan J; Concha H; Gaughan U; Hassan M
Article: EXPERIMENTAL HEMATOLOGY. 2006;34(1):35-43

A pharmacodynamic study of 5-azacytidine in the P39 cell line.

Khan R; Aggerholm A; Hokland P; Hassan M; Hellström-Lindberg E
Article: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 2006;27(1):54-61

Pharmacogenetics of cyclophosphamide in patients with hematological malignancies.

Xie H; Griskevicius L; Ståhle L; Hassan Z; Yasar U; Rane A; Broberg U; Kimby E; Hassan M
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2005;75(3):206-211

The effect of ciprofloxacin on cyclophosphamide pharmacokinetics in patients with non-Hodgkin lymphoma.

Afsharian P; Möllgård L; Hassan Z; Xie H; Kimby E; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2005;36(5):411-415

Cell-mediated immune responses to influenza vaccination in healthy volunteers and allogeneic stem cell transplant recipients.

Avetisyan G; Ragnavölgyi E; Toth GT; Hassan M; Ljungman P
Article: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2005;821(1):75-80

Stability, pKa and plasma protein binding of roscovitine.

Vita M; Abdel-Rehim M; Nilsson C; Hassan Z; Skansen P; Wan H; Meurling L; Hassan M
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2005;141(2):238-247

Bacterial lipopolysaccharide both renders resistant mice susceptible to mercury-induced autoimmunity and exacerbates such autoimmunity in susceptible mice.

Abedi-Valugerdi M; Nilsson C; Zargari A; Gharibdoost F; DePierre JW; Hassan M
Article: TRANSPLANTATION. 2005;79(11):1607-1614

Fetal mesenchymal stem-cell engraftment in bone after in utero transplantation in a patient with severe osteogenesis imperfecta.

Le Blanc K; Götherström C; Ringdén O; Hassan M; McMahon R; Horwitz E; Anneren G; Axelsson O; Nunn J; Ewald U; Nordén-Lindeberg S; Jansson M; Dalton A; Aström E; Westgren M
Article: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 2005;25(1):91-103

Tissue distribution, pharmacokinetics and identification of roscovitine metabolites in rat.

Vita M; Abdel-Rehim M; Olofsson S; Hassan Z; Meurling L; Sidén A; Sidén M; Pettersson T; Hassan M
Article: ANALYTICA CHIMICA ACTA. 2005;539(1-2):35-39

Microextraction in packed syringe/liquid chromatography/electrospray tandem mass spectrometry for quantification of olomoucine in human plasma samples

Abdel-Rehim M; Skansen P; Vita M; Hassan Z; Blomberg L; Hassan M
Article: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2005;817(2):303-307

Development and validation of a liquid chromatography and tandem mass spectrometry method for determination of roscovitine in plasma and urine samples utilizing on-line sample preparation.

Vita M; Skansen P; Hassan M; Abdel-Rehim M
Article: XENOBIOTICA. 2005;35(3):239-251

Cyclophosphamide induces mRNA, protein and enzyme activity of cytochrome P450 in rat.

Xie H; Afsharian P; Terelius Y; Mirghani RA; Yasar U; Hagbjörk A-L; Lundgren S; Hu Y; Rane A; Hassan M
Article: EXPERIMENTAL HEMATOLOGY. 2005;33(3):380-387

Effect of altering administration order of busulphan and cyclophosphamide on the myeloablative and immunosuppressive properties of the conditioning regimen in mice.

Nilsson C; Forsman J; Hassan Z; Abedi-Valugerdi M; O'Connor C; Concha H; Jansson M; Hassan M
Article: IMMUNOLOGY. 2005;114(3):428-437

Exposure to mercuric chloride during the induction phase and after the onset of collagen-induced arthritis enhances immune/autoimmune responses and exacerbates the disease in DBA/1 mice.

Hansson M; Djerbi M; Rabbani H; Mellstedt H; Gharibdoost F; Hassan M; Depierre JW; Abedi-Valugerdi M
Article: TRANSPLANTATION. 2004;78(1):154-157

Lung epithelial cells and type II pneumocytes of donor origin after allogeneic hematopoietic stem cell transplantation.

Mattsson J; Jansson M; Wernerson A; Hassan M
Article: LANCET. 2004;363(9419):1439-1441

Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells.

Le Blanc K; Rasmusson I; Sundberg B; Götherström C; Hassan M; Uzunel M; Ringdén O
Article: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2004;34(2):425-431

Analysis of roscovitine using novel high performance liquid chromatography and UV-detection method: pharmacokinetics of roscovitine in rat.

Vita M; Meurling L; Pettersson T; Cruz-Sidén M; Sidén A; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2003;32(5):477-483

Fractionated TBI correlates with less T cell mixed chimerism but increased risk of relapse compared to busulphan in patients with haematological malignancies after allogeneic stem cell transplantation.

Mattsson J; Uzunel M; Remberger M; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2003;32(4):349-354

N-acetyl-L-cysteine does not affect the pharmacokinetics or myelosuppressive effect of busulfan during conditioning prior to allogeneic stem cell transplantation.

Sjöö F; Aschan J; Barkholt L; Hassan Z; Ringdén O; Hassan M
Article: CLINICAL CANCER RESEARCH. 2003;9(7):2447-2456

Immunization of colorectal carcinoma patients with a recombinant canarypox virus expressing the tumor antigen Ep-CAM/KSA (ALVAC-KSA) and granulocyte macrophage colony- stimulating factor induced a tumor-specific cellular immune response.

Ullenhag GJ; Frödin J-E; Mosolits S; Kiaii S; Hassan M; Bonnet MC; Moingeon P; Mellstedt H; Rabbani H
Article: THERAPEUTIC DRUG MONITORING. 2003;25(3):400-406

On-line derivatization utilizing solid-phase microextraction (SPME) for determination of busulphan in plasma using gas chromatography-mass spectrometry (GC-MS).

Abdel-Rehim M; Hassan Z; Blomberg L; Hassan M
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2003;59(2):103-109

Bioactivation of cyclophosphamide: the role of polymorphic CYP2C enzymes.

Griskevicius L; Yasar U; Sandberg M; Hidestrand M; Eliasson E; Tybring G; Hassan M; Dahl M-L
Article: BONE MARROW TRANSPLANTATION. 2003;31(6):429-435

The effect of metronidazole on busulfan pharmacokinetics in patients undergoing hematopoietic stem cell transplantation.

Nilsson C; Aschan J; Hentschke P; Ringdén O; Ljungman P; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2003;31(3):197-203

Alteration of pharmacokinetics of cyclophosphamide and suppression of the cytochrome p450 genes by ciprofloxacin.

Xie H-J; Broberg U; Griskevicius L; Lundgren S; Carlens S; Meurling L; Paul C; Rane A; Hassan M
Article: PHARMACOGENOMICS JOURNAL. 2003;3(1):53-61

Role of polymorphic human CYP2B6 in cyclophosphamide bioactivation.

Xie H-J; Yasar U; Lundgren S; Griskevicius L; Terelius Y; Hassan M; Rane A
Article: BONE MARROW TRANSPLANTATION. 2002;30(12):833-841

A phase II trial of liposomal busulphan as an intravenous myeloablative agent prior to stem cell transplantation: 500 mg/m(2) as a optimal total dose for conditioning.

Hassan M; Nilsson C; Hassan Z; Gungor T; Aschan J; Winiarski J; Hentschke P; Ringdén O; Eber S; Seger R; Ljungman P
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2002;449(3):197-205

Effect of cyclophosphamide on gene expression of cytochromes p450 and beta-actin in the HL-60 cell line.

Xie H-J; Lundgren S; Broberg U; Finnström N; Rane A; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2002;30(3):141-147

The effect of modulation of glutathione cellular content on busulphan-induced cytotoxicity on hematopoietic cells in vitro and in vivo.

Hassan Z; Hellström-Lindberg E; Alsadi S; Edgren M; Hägglund H; Hassan M
Article: THERAPEUTIC DRUG MONITORING. 2002;24(3):405-409

Simple method based on fluorescent detection for the determination of 4-hydroxycyclophosphamide in plasma.

Griskevicius L; Meurling L; Hassan M
Article: BRITISH JOURNAL OF CANCER. 2001;85(12):2004-2009

Bioavailability and dose-dependent anti-tumour effects of 9-cis retinoic acid on human neuroblastoma xenografts in rat.

Ponthan F; Kogner P; Bjellerup P; Klevenvall L; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2001;28(7):657-664

Population pharmacokinetic analysis resulting in a tool for dose individualization of busulphan in bone marrow transplantation recipients.

Sandström M; Karlsson MO; Ljungman P; Hassan Z; Jonsson EN; Nilsson C; Ringden O; Oberg G; Bekassy A; Hassan M
Article: LEUKEMIA. 2001;15(8):1240-1247

The pharmacodynamic effect of busulfan in the P39 myeloid cell line in vitro.

Hassan Z; Hassan M; Hellström-Lindberg E
Article: CLINICAL CANCER RESEARCH. 2001;7(5):1163-1170

Alteration of interleukin 2 (IL-2) pharmacokinetics and function by IL-2 antibodies induced after treatment of colorectal carcinoma patients with a combination of monoclonal antibody 17-1A, granulocyte macrophage colony-stimulating factor, and IL-2.

Hjelm Skog AL; Wadhwa M; Hassan M; Gharizadeh B; Bird C; Ragnhammar P; Thorpe R; Mellstedt H
Article: BONE MARROW TRANSPLANTATION. 2001;27(5):479-485

Pharmacokinetics of liposomal busulphan in man.

Hassan Z; Ljungman P; Ringdén O; Winiarski J; Nilsson C; Aschan J; Whitley HR; Hassan M
Article: JOURNAL OF LIPID RESEARCH. 2001;42(1):70-78

Evidence that the major oxysterols in human circulation originate from distinct pools of cholesterol: a stable isotope study.

Meaney S; Hassan M; Sakinis A; Lütjohann D; von Bergmann K; Wennmalm A; Diczfalusy U; Björkhem I
Article: LEUKEMIA. 2000;14(11):1954-1959

A phase I/II study of multiple-dose intravenous busulfan as myeloablation prior to stem cell transplantation.

Olavarria E; Hassan M; Eades A; Nilsson C; Timms A; Matthews J; Craddock C; Kanfer E; Apperley J; Goldman J
Article: THERAPEUTIC DRUG MONITORING. 2000;22(4):383-385

Ketobemidone may alter busulfan pharmacokinetics during high-dose therapy.

Hassan M; Svensson JO; Nilsson C; Hentschke P; Al-Shurbaji A; Aschan J; Ljungman P; Ringdén O
Article: BONE MARROW TRANSPLANTATION. 2000;25(9):915-924

The effect of busulphan on the pharmacokinetics of cyclophosphamide and its 4-hydroxy metabolite: time interval influence on therapeutic efficacy and therapy-related toxicity.

Hassan M; Ljungman P; Ringdén O; Hassan Z; Oberg G; Nilsson C; Békassy A; Bielenstein M; Abdel-Rehim M; Georén S; Astner L
Article: JOURNAL OF SEPARATION SCIENCE. 2000;23(2):156-157

Capillary gas chromatography of trichlorophenols using ammonia as carrier gas

Abdel-Rehim M; Hassan M
Article: NUCLEAR MEDICINE AND BIOLOGY. 1999;26(8):931-936

Biodistribution of liposomal 131I-VIP in rat using gamma camera.

Refai E; Jonsson C; Andersson M; Jacobsson H; Larsson S; Kogner P; Hassan M
Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 1999;48(5):669-677

A mechanism-based pharmacokinetic-enzyme model for cyclophosphamide autoinduction in breast cancer patients.

Hassan M; Svensson US; Ljungman P; Björkstrand B; Olsson H; Bielenstein M; Abdel-Rehim M; Nilsson C; Johansson M; Karlsson MO
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1999;63(3):163-170

The influence of interferon-alpha on the pharmacokinetics of cyclophosphamide and its 4-hydroxy metabolite in patients with multiple myeloma.

Hassan M; Nilsson C; Olsson H; Lundin J; Osterborg A
Article: NUCLEAR MEDICINE AND BIOLOGY. 1999;26(4):413-420

In vivo dynamic distribution of 131I-glucagon-like peptide-1 (7-36) amide in the rat studied by gamma camera.

Hassan M; Eskilsson A; Nilsson C; Jonsson C; Jacobsson H; Refai E; Larsson S; Efendic S
Article: LIFE SCIENCES. 1999;65(2):165-174

In vivo evaluation of the biodistribution of 11C-labeled PD153035 in rats without and with neuroblastoma implants.

Fredriksson A; Johnström P; Thorell JO; von Heijne G; Hassan M; Eksborg S; Kogner P; Borgström P; Ingvar M; Stone-Elander S
Article: BONE MARROW TRANSPLANTATION. 1998;22(9):913-918

Liposomal busulphan: bioavailability and effect on bone marrow in mice.

Hassan Z; Nilsson C; Hassan M
Article: CANCER CHEMOTHERAPY AND PHARMACOLOGY. 1998;42(6):471-478

Pharmacokinetics and distribution of liposomal busulfan in the rat: a new formulation for intravenous administration.

Hassan M; Hassan Z; Nilsson C; Rehim MA; Kumlien S; Elfsson B; Kållberg N
Article: BONE MARROW TRANSPLANTATION. 1997;20(11):909-913

High busulfan concentrations are associated with increased transplant-related mortality in allogeneic bone marrow transplant patients.

Ljungman P; Hassan M; Békássy AN; Ringdén O; Oberg G
Article: BONE MARROW TRANSPLANTATION. 1996;18(5):843-850

Busulphan kinetics and limited sampling model in children with leukemia and inherited disorders.

Hassan M; Fasth A; Gerritsen B; Haraldsson A; Syrůcková Z; van den Berg H; Sandström M; Karlsson M; Kumlien S; Vossen J
Article: PEDIATRIC HEMATOLOGY AND ONCOLOGY. 1996;13(2):143-150

Infection-associated hemophagocytic syndrome complicated by infectious lymphoproliferation: a case report.

Syrůcková Z; Starý J; Sedlácek P; Smísek P; Vavrinec J; Komrska V; Roubalová K; Vandasová J; Sintáková B; Housková J; Hassan M
Article: JOURNAL OF SEPARATION SCIENCE. 1996;8(2):151-156

Enantiomer separation of underivatized tocainide and related compounds by CGC using ammonia as carrier gas

AbdelRehim M; Karlen A; Zhang L; Kamel M; Hassan M
Article: JOURNAL OF SEPARATION SCIENCE. 1995;18(12):757-759

Effect of ammonia on the response of the electron capture detector (ECD)

AbdelRehim M; Kamel M; Hassan M
Article: EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS. 1995;20(3):225-232

Kinetics and metabolism of 2-chloro-2'-deoxyadenosine and 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine in the isolated perfused rat liver.

Albertioni F; Hassan M; Silberring J; Liliemark J
Article: BONE MARROW TRANSPLANTATION. 1995;15(6):869-871

Busulfan concentration in relation to permanent alopecia in recipients of bone marrow transplants.

Ljungman P; Hassan M; Békássy AN; Ringdén O; Oberg G
Article: INTERNATIONAL PSYCHOGERIATRICS. 1995;7(1):75-83

One year on tacrine (THA): clinical and biochemical effects in patients with dementia of the Alzheimer type.

Ahlin A; Junthé T; Hassan M; Nybäck H
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All other publications

Editorial comment: CELL JOURNAL. 2023;25(10):738-740

A Shadow of Knowledge in Stem Cell Science.

Omid-Shafiee S; Hassan M; Nussler AK; Mustapha N; Vosough M
Review: CELLS. 2023;12(18):2260

Circulating Tumor Cells as a Promising Tool for Early Detection of Hepatocellular Carcinoma.

Salehi M; Lavasani ZM; Keshavarz Alikhani H; Shokouhian B; Hassan M; Najimi M; Vosough M
Review: CELL JOURNAL. 2023;25(5):281-290

Platelet-Rich Plasma in Regenerative Medicine: Possible Applications in Management of Burns and Post-Burn Scars: A Review.

Hosseini MS; Nouri M; Zarrabi M; Fatemi MJ; Shpichka A; Timashev P; Hassan M; Vosough M
Review: BIOMEDICINE & PHARMACOTHERAPY. 2023;161:114487

Autophagy orchestrates resistance in hepatocellular carcinoma cells.

Seydi H; Nouri K; Rezaei N; Tamimi A; Hassan M; Mirzaei H; Vosough M
Review: BIOMEDICAL MATERIALS. 2023;18(3):032001

Progress and promise of cell sheet assisted cardiac tissue engineering in regenerative medicine.

Abdolahzadeh H; Rad NK; Shpichka A; Golroo R; Rahi K; Timashev P; Hassan M; Vosough M
Review: EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY. 2023;17(3):237-249

Cell and cell-derivative-based therapy for liver diseases: current approaches and future promises.

Zahmatkesh E; Khoshdel Rad N; Hossein-Khannazer N; Mohamadnejad M; Gramignoli R; Najimi M; Malekzadeh R; Hassan M; Vosough M
Review: JOURNAL OF CELLULAR PHYSIOLOGY. 2022;237(11):3984-4000

Hepatogenesis and hepatocarcinogenesis: Alignment of the main signaling pathways.

Shokouhian B; Aboulkheyr Es H; Negahdari B; Tamimi A; Shahdoust M; Shpichka A; Timashev P; Hassan M; Vosough M
Review: JOURNAL OF PERSONALIZED MEDICINE. 2022;12(11):1797

Cardiovascular Complications in Hematopoietic Stem Cell Transplanted Patients.

Zhao Y; He R; Oerther S; Zhou W; Vosough M; Hassan M
Review: MOLECULAR BIOLOGY REPORTS. 2022;49(2):1545-1549

Mini review ATF4 and GRP78 as novel molecular targets in ER-Stress modulation for critical COVID-19 patients.

Shahriari-Felordi M; Alikhani HK; Hashemian S-MR; Hassan M; Vosough M
Editorial comment: EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY. 2022;16(1):1-3

COVID-19 and hygiene hypothesis: increment of the inflammatory bowel diseases in next generation?

Shahrbaf MA; Hassan M; Vosough M
Review: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2022;10:894800

Regulatory Non-Coding RNAs in Familial Hypercholesterolemia, Theranostic Applications.

Keshavarz Alikhani H; Pourhamzeh M; Seydi H; Shokoohian B; Hossein-Khannazer N; Jamshidi-Adegani F; Al-Hashmi S; Hassan M; Vosough M
Review: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2021;25(18):8602-8614

Advanced therapeutic modalities in hepatocellular carcinoma: Novel insights.

Shokoohian B; Negahdari B; Aboulkheyr Es H; Abedi-Valugerdi M; Baghaei K; Agarwal T; Maiti TK; Hassan M; Najimi M; Vosough M
Review: PHARMACOLOGY & THERAPEUTICS. 2021;220:107714

Novel molecular targets in gastric adenocarcinoma.

Ramezankhani R; Solhi R; Es HA; Vosough M; Hassan M
Review: ACS NANO. 2021;15(3):3754-3807

X-ray-Based Techniques to Study the Nano-Bio Interface.

Sanchez-Cano C; Alvarez-Puebla RA; Abendroth JM; Beck T; Blick R; Cao Y; Caruso F; Chakraborty I; Chapman HN; Chen C; Cohen BE; Conceição ALC; Cormode DP; Cui D; Dawson KA; Falkenberg G; Fan C; Feliu N; Gao M; Gargioni E; Glüer C-C; Grüner F; Hassan M; Hu Y; Huang Y; Huber S; Huse N; Kang Y; Khademhosseini A; Keller TF; Körnig C; Kotov NA; Koziej D; Liang X-J; Liu B; Liu S; Liu Y; Liu Z; Liz-Marzán LM; Ma X; Machicote A; Maison W; Mancuso AP; Megahed S; Nickel B; Otto F; Palencia C; Pascarelli S; Pearson A; Peñate-Medina O; Qi B; Rädler J; Richardson JJ; Rosenhahn A; Rothkamm K; Rübhausen M; Sanyal MK; Schaak RE; Schlemmer H-P; Schmidt M; Schmutzler O; Schotten T; Schulz F; Sood AK; Spiers KM; Staufer T; Stemer DM; Stierle A; Sun X; Tsakanova G; Weiss PS; Weller H; Westermeier F; Xu M; Yan H; Zeng Y; Zhao Y; Zhao Y; Zhu D; Zhu Y; Parak WJ
Review: FRONTIERS IN MICROBIOLOGY. 2021;12:785856

Application of Stem Cell-Derived Extracellular Vesicles as an Innovative Theranostics in Microbial Diseases.

Keshavarz Alikhani H; Shokoohian B; Rezasoltani S; Hossein-Khannazer N; Yadegar A; Hassan M; Vosough M
Editorial comment: TRANSPLANTATION AND CELLULAR THERAPY. 2020;26(9):e235-e236

Response to Kawedia et al Letter to Editor in Response to the Article by McCune Et Al "Harmonization of Busulfan Plasma Exposure Unit (BPEU): A Community-Initiated Consensus Statement".

Dupuis LL; Quinones CM; Ritchie J; Carpenter PA; Bauters T; Yeh RF; Anasetti C; Boelens JJ; Hamerschlak N; Hassan M; Kang HJ; Kanda Y; Paci A; Perales M-A; Shaw PJ; Seewaldt VL; Savani BN; Militano O; Pulsipher MA; McCune JS
Editorial comment: FRONTIERS IN NEUROANATOMY. 2016;10:14

Commentary: Impact of a deletion of the full-length and short isoform of p75NTR on cholinergic innervation and the population of postmitotic doublecortin positive cells in the dentate gyrus.

Sabry MA; Fares M; Folkesson R; Al-Ramadan M; Alabkal J; Al-Kafaji G; Hassan M
Editorial comment: HAEMATOLOGICA. 2014;99(7):1124-1127

Hematologic malignancies in elderly patients.

Hassan M; Abedi-Valugerdi M
Review: PHARMACOGENOMICS. 2013;14(1):75-87

Role of pharmacogenetics in busulfan/cyclophosphamide conditioning therapy prior to hematopoietic stem cell transplantation.

Hassan M; Andersson BS
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2011;17(2):S345

DYNAMICS OF DONOR T CELL ACTIVATION DURING EARLY PHASE OF GRAFT VERSUS HOST DISEASE (GVHD): DONOR ANTIGEN PRESENTING CELLS CAN ACTIVATE ALLOGENEIC T CELLS

Sadeghi B; Al-Hashmi S; Hassan Z; Hassan M
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2009;15(2):127

N-ACETYL-L-CYSTEINE PROMOTES T CELL MEDIATED IMMUNITY IN ALLOGENEIC SETTINGS IN VIVO AND IN VITRO

Karlsson H; Nava S; Remberger M; Hassan Z; Hassan M; Ringden O
Meeting abstract: LEUKEMIA RESEARCH. 2007;31:S62-S63

Hypomethylation and apoptosis in 5-azacytidine treated myeloid cells

Khan R; Schmidt-Mende J; Karimi M; Forsblom A-M; Gogvadze V; Hassan M; Ekstrom TJ; Zhivotovsky B; Hellstrom-Lindberg E
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2007;13(2):70-71

The role of human CYP2B6 polymorphism in the bioactivation of cyclophosphamide using CDNA expressed enzymes

Afsharian P; Teredius Y; Hidestrand M; Ingelman-Sundberg M; Hassan M; Lundgren S
Meeting abstract: BLOOD. 2006;108(11):97A

Effect of busulphan dose adjustment on regimen-related toxicity.

Hassan Z; Remberger M; Ringden O; Oberg G; Bekassy AN; Hassan M
Meeting abstract: BLOOD. 2005;106(11):193B

The effect of repeated administration of cyclophosphamide on CYP2B1 and 2B2 in rat.

Afsharian P; Terelius Y; Lundgren S; Hassan M
Meeting abstract: BLOOD. 2005;106(11):60A

Long-term follow-up of patients treated by gene therapy for X-linked chronic granulomatous disease.

Ott MG; Grez M; Stein S; Siler U; Koehl U; Kuehlcke K; Schmidt M; Schilz A; Kunkel H; Naundorf S; Brinkmann A; Hassan M; von Kalle C; Trasher A; Seger R; Hoelzer D
Published paper: PEDIATRIC BLOOD & CANCER. 2001;36(1):127-131

The vitamin A analogues: 13-cis retinoic acid, 9-cis retinoic acid, and Ro 13-6307 inhibit neuroblastoma tumour growth in vivo.

Ponthan F; Borgström P; Hassan M; Wassberg E; Redfern CP; Kogner P
Published paper: PEDIATRIC RESEARCH. 1999;46(3):328-332

The somatostatin analogue octreotide inhibits neuroblastoma growth in vivo.

Borgström P; Hassan M; Wassberg E; Refai E; Jonsson C; Larsson SA; Jacobsson H; Kogner P
Review: MEDICAL ONCOLOGY. 1999;16(3):166-176

The role of busulfan in bone marrow transplantation.

Hassan M
Published paper: EUROPEAN JOURNAL OF CANCER. 1997;33(12):2084-2089

Somatostatin in neuroblastoma and ganglioneuroma.

Kogner P; Borgström P; Bjellerup P; Schilling FH; Refai E; Jonsson C; Dominici C; Wassberg E; Bihl H; Jacobsson H; Theodorsson E; Hassan M
Review: LEUKEMIA & LYMPHOMA. 1996;22(5-6):395-407

Aspects concerning busulfan pharmacokinetics and bioavailability.

Hassan M; Ehrsson H; Ljungman P
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Professor, Senior, Department of Laboratory Medicine, Karolinska Institutet, 2019-

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Docent, Karolinska Institutet, 1994

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