Mohsen Moslem
Affiliated to Research
E-mail: mohsen.moslem@ki.se
Visiting address: BioClinicum J5:20, Akademiska stråket 1, Karolinska universitetssjukhu, 17164 Solna
Postal address: K8 Klinisk neurovetenskap, K8 Neuro Svenningsson, 171 77 Stockholm
About me
- Senior Stem Cell Scientist with 10+ years experience in advanced stem cell
culture and disease modeling.
Doctor of Anatomy and Embryology with focus on stem cell and development,
with more than 10 years of research and teaching experience. I defended my
PhD in 2012 at Royan Institute and did 3 international postdocs at Hannover
Medical School (MHH), Hannover, Germany , Ludwig Maximillians University
(LMU), Munich, Germany and Karolinska Institute, Sweden.
Research
- My specific field of interest in stem cell biology is disease modeling of
Parkinson's disease.
List of Publications:
Partial Monosomy 21 Mirrors Gene Expression of Trisomy 21 in a
Patient-Derived Neuroepithelial Stem Cell Model. [1] Schuy J, Eisfeldt J,
Pettersson M, Shahrokhshahi N, *Moslem M*, Nilsson D, Dahl N, Shahsavani M,
Falk A, Lindstrand A.Front Genet. 2022 Feb 4 - 12:803683.
Crosstalk between astrocytes and microglia results in increased degradation
of α-synuclein and amyloid-β aggregates. [2] Rostami J, Mothes T,
Kolahdouzan M, Eriksson O, *Moslem M*, Bergström J, Ingelsson M,
O'Callaghan P, Healy LM, Falk A, Erlandsson A.J Neuroinflammation. 2021 Jun
3 - 18(1):124.
Modeling SHH-driven medulloblastoma with patient iPS cell-derived neural stem
cells. [3] Susanto E, Marin Navarro A, Zhou L, Sundström A, van Bree N,
Stantic M, *Moslem M*, Tailor J, Rietdijk J, Zubillaga V, Hübner JM,
Weishaupt H, Wolfsberger J, Alafuzoff I, Nordgren A, Magnaldo T, Siesjö P,
Johnsen JI, Kool M, Tammimies K, Darabi A, Swartling FJ, Falk A, Wilhelm
M.Proc Natl Acad Sci U S A. 2020 Aug 18 - 117(33):20127-20138
Ataxia in Patients With Bi-Allelic /NFASC/ Mutations and Absence of
Full-Length NF186. [4] Kvarnung M, Shahsavani M, Taylan F, *Moslem M*,
Breeuwsma N, Laan L, Schuster J, Jin Z, Nilsson D, Lieden A, Anderlid BM,
Nordenskjöld M, Syk Lundberg E, Birnir B, Dahl N, Nordgren A, Lindstrand A,
Falk A.Front Genet. 2019 Sep 24 - 10:896
Single cell analysis of autism patient with bi-allelic NRXN1-alpha deletion
reveals skewed fate choice in neural progenitors and impaired neuronal
functionality. [5] Lam M, *Moslem M*, Bryois J, Pronk RJ, Uhlin E,
Ellström ID, Laan L, Olive J, Morse R, Rönnholm H, Louhivuori L, Korol SV,
Dahl N, Uhlén P, Anderlid BM, Kele M, Sullivan PF, Falk A.Exp Cell Res. 2019
Oct 1 - 383(1):111469.
Stem cell models of schizophrenia, what have we learned and what is the
potential? [6] *Moslem M*, Olive J, Falk A.Schizophr Res. 2019 Aug - 210:3-12
Kindlin-2 Modulates the Survival, Differentiation, and Migration of Induced
Pluripotent Cell-Derived Mesenchymal Stromal Cells. [7] *Moslem M*,
Eggenschwiler R, Wichmann C, Buhmann R, Cantz T, Henschler R.Stem Cells Int.
2017 - 2017:7316354
Improved bi-allelic modification of a transcriptionally silent locus in
patient-derived iPSC by Cas9 nickase. [8] Eggenschwiler R, *Moslem M*,
Fráguas MS, Galla M, Papp O, Naujock M, Fonfara I, Gensch I, Wähner A,
Beh-Pajooh A, Mussolino C, Tauscher M, Steinemann D, Wegner F, Petri S,
Schambach A, Charpentier E, Cathomen T, Cantz T.Sci Rep. 2016 Dec 2 - 6:38198.
Mesenchymal Stem/Stromal Cells Derived from Induced Pluripotent Stem Cells
Support CD34(pos) Hematopoietic Stem Cell Propagation and Suppress
Inflammatory Reaction. [9] *Moslem M*, Eberle I, Weber I, Henschler R, Cantz
T.Stem Cells Int. 2015 - 2015:843058.
Therapeutic potential of human induced pluripotent stem cell-derived
mesenchymal stem cells in mice with lethal fulminant hepatic failure.
[10] *Moslem M*, Valojerdi MR, Pournasr B, Muhammadnejad A, Baharvand H.Cell
Transplant. 2013 - 22(10):1785-99.
Engineered MSCs from Patient-Specific iPS Cells. [11] Eberle I, *Moslem M*,
Henschler R, Cantz T.Adv Biochem Eng Biotechnol. 2013 - 130:1-17
Differentiation and transplantation of human induced pluripotent stem
cell-derived hepatocyte-like cells. [12] Asgari S, *Moslem M*,
Bagheri-Lankarani K, Pournasr B, Miryounesi M, Baharvand H.Stem Cell Rev Rep.
2013 Aug - 9(4):493-504.
Cell-based therapeutics for liver disorders. [13] Vosough M, *Moslem M*,
Pournasr B, Baharvand H.Br Med Bull. 2011 - 100:157-72
[1] https://pubmed.ncbi.nlm.nih.gov/35186010/
[2] https://pubmed.ncbi.nlm.nih.gov/34082772/
[3] https://pubmed.ncbi.nlm.nih.gov/32747535/
[4] https://pubmed.ncbi.nlm.nih.gov/31608123/
[5] https://pubmed.ncbi.nlm.nih.gov/31302032/
[6] https://pubmed.ncbi.nlm.nih.gov/30587427/
[7] https://pubmed.ncbi.nlm.nih.gov/28163724/
[8] https://pubmed.ncbi.nlm.nih.gov/27910942/
[9] https://pubmed.ncbi.nlm.nih.gov/26185499/
[10] https://pubmed.ncbi.nlm.nih.gov/23394436/
[11] https://pubmed.ncbi.nlm.nih.gov/22915200/
[12] https://pubmed.ncbi.nlm.nih.gov/22076752/
[13] https://pubmed.ncbi.nlm.nih.gov/21771778/
All other publications
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Review: SCHIZOPHRENIA RESEARCH. 2019;210:3-12