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About me

Associate Professor at Karolinska Institutet with over ten years of experience in research and education in toxicology and environmental medicine. Risk assessment and science-to-policy is my main field of interest and I have active projects both at Swetox (Swedish center for toxicological sciences) and at the Institute of Environmental Medicine.
I enjoy working in the truely multi-disciplinary research field of chemical risk assessment and has a large network of contacts among Swedish and international agencies and organizations.
Beside ordinary research activities I am chairing the National Committee for European Registered toxicologists (ERT) and are a Swedish representative the the Nordic Expert Group, a Nordic collaboration for production of criteria documents on chemicals for occupational exposure limits.

Research description

Current research projects as main project leader:

  • Experimental design aligned with dose-response modelling as a means for 3R in toxicity testing (Financial support: Swedish Research Council)
  • Bayesian dose-response modelling aligned with experimental design as means to improve chemical risk assessment (Financial support: Swedish Research Council)
  • Kemiska olyckor i arbetslivet – systematisk analys av giftinformationscentralens arbetsmiljörelaterade data (Financial support: AFA Försäkring)

Other reasech projects:

  • EDC-MixRisk, safe chemicals for future generations (Financial support: European Union’s Horizon 2020)
  • EDC-2020, a project about endocrine disrupting chemicals (Financial support: Formas)
  • Elimination and effects of PFAS in drinking water in Sweden (Collaboration with Lund University).
  • Modern methods for estimation of in vivo dose and genotoxic potency as components for cancer risk assessment (Collaboration with Stockholm University).
  • DECRA: Developing Comparative Risk Assessment into a useful tool for substituting hazardous chemicals (Collaboration with Gothenburg University)

Teaching portfolio

My teaching activities include lectures, cource leadership, supervising master and PhD student.

I have been the main supervisor for two PhD students:

  • Mia Johansson (2016) - Asthmatics as a susceptible population in health risk assessment of airbourne chemicals
  • Joakim Ringblom (2016) - Worth weighting for - Studies on benchmark dose analysis in relation to animal ethics in toxicity testing

Publications

Assigning ethical weights to clinical signs observed during toxicity testing
Ringblom J, Törnqvist E, Hansson So, Rudén C, Öberg M
ALTEX 2017;34(1):148-156

Comparison of airway response in naïve and ovalbumin-sensitized mice during short-term inhalation exposure to chlorine
Johansson M, Gustafsson Å, Johanson G, Öberg M
Inhalation toxicology 2017;29(2):82-91

Influence of Distribution of Animals between Dose Groups on Estimated Benchmark Dose and Animal Distress for Quantal Responses
Kalantari F, Ringblom J, Sand S, Öberg M
Risk analysis : an official publication of the Society for Risk Analysis 2017;():-

Does industry take the susceptible subpopulation of asthmatic individuals into consideration when setting derived no-effect levels?
Johansson Mk, Johanson G, Öberg M, Schenk L
Journal of applied toxicology : JAT 2016;36(11):1379-91

Evaluation of the experimental basis for assessment factors to protect individuals with asthma from health effects during short-term exposure to airborne chemicals
Johansson Mk, Johanson G, Öberg M
Critical reviews in toxicology 2016;46(3):241-60

Uppsala Consensus Statement on Environmental Contaminants and the Global Obesity Epidemic
Lind L, Lind Pm, Lejonklou Mh, Dunder L, Bergman Å, Guerrero-bosagna C, et al
Environmental health perspectives 2016;124(5):A81-3

Inhibitory effects on osteoblast differentiation in vitro by the polychlorinated biphenyl mixture Aroclor 1254 are mainly associated with the dioxin-like constituents
Herlin M, Öberg M, Ringblom J, Joseph B, Korkalainen M, Viluksela M, et al
Toxicology in vitro : an international journal published in association with BIBRA 2015;29(5):876-83

Advancing the 3Rs in regulatory toxicology - Carcinogenicity testing: Scope for harmonisation and advancing the 3Rs in regulated sectors of the European Union
Annys E, Billington R, Clayton R, Bremm Kd, Graziano M, Mckelvie J, et al
Regulatory toxicology and pharmacology : RTP 2014;69(2):234-42

Aerial Application of Mancozeb and Urinary Ethylene Thiourea (ETU) Concentrations among Pregnant Women in Costa Rica: The Infants' Environmental Health Study (ISA)
De Joode Bv, Mora Am, Cordoba L, Cano Jc, Quesada R, Faniband M, et al
ENVIRONMENTAL HEALTH PERSPECTIVES 2014;122(12):1321-8

Strategic focus on 3R principles reveals major reductions in the use of animals in pharmaceutical toxicity testing
Törnqvist E, Annas A, Granath B, Jalkesten E, Cotgreave I, Öberg M
PloS one 2014;9(7):e101638-

How are asthmatics included in the derivation of guideline values for emergency planning and response?
Johansson Mkv, Johanson G, Oberg M
REGULATORY TOXICOLOGY AND PHARMACOLOGY 2012;63(3):461-70

Indigenous children living nearby plantations with chlorpyrifos-treated bags have elevated 3,5,6-trichloro-2-pyridinol (TCPy) urinary concentrations
De Joode Bv, Barraza D, Ruepert C, Mora Am, Cordoba L, Oberg M, et al
ENVIRONMENTAL RESEARCH 2012;:17-26

The point of transition on the dose-effect curve as a reference point in the evaluation of in vitro toxicity data
Sand S, Ringblom J, Hakansson H, Oberg M
JOURNAL OF APPLIED TOXICOLOGY 2012;32(10):843-9

Worldwide burden of disease from exposure to second-hand smoke: a retrospective analysis of data from 192 countries
Oberg M, Jaakkola Ms, Woodward A, Peruga A, Pruss-ustun A
LANCET 2011;377(9760):139-46

Benchmark dose approaches in chemical health risk assessment in relation to number and distress of laboratory animals
Oberg M
REGULATORY TOXICOLOGY AND PHARMACOLOGY 2010;58(3):451-4

Discrepancy among acute guideline levels for emergency response
Oberg M, Palmen N, Johanson G
JOURNAL OF HAZARDOUS MATERIALS 2010;184(1-3):439-47

HEALTH IMPACT ASSESSMENT OF ENVIRONMENTAL TOBACCO SMOKE IN EUROPEAN CHILDREN: SUDDEN INFANT DEATH SYNDROME AND ASTHMA EPISODES
Boldo E, Medina S, Oberg M, Puklova V, Mekel O, Patja K, et al
PUBLIC HEALTH REPORTS 2010;125(3):478-87

Toxicity of Bromkal 70-5DE, a technical mixture of polybrominated diphenyl ethers, following 28 d of oral exposure in rats and impact of analysed impurities
Oberg M, Westerholm E, Fattore E, Stern N, Hanberg A, Haglund P, et al
CHEMOSPHERE 2010;80(2):137-43

Adult smoking as a proxy for environmental tobacco smoke exposure among children - Comparing the impact of the level of information in Estonia, Finland and Latvia
Patja K, Hakala S, Prattala R, Ojala K, Boldo E, Oberg M
PREVENTIVE MEDICINE 2009;49(2-3):240-4

Exposure to dioxin-like pollutants via different food commodities in Swedish children and young adults
Bergkvist C, Oberg M, Appelgren M, Becker W, Aune M, Ankarberg Eh, et al
FOOD AND CHEMICAL TOXICOLOGY 2008;46(11):3360-7

Occurrence and levels of environmental chemicals in human milk in the general population
Branting Tj, Ruden C, Oberg M, Bjorkdahl C
TOXICOLOGY LETTERS 2006;:S117-S117

Identification of the tryptophan photoproduct 6-formylindolo[3,2-b]carbazole, in cell culture medium, as a factor that controls the background aryl hydrocarbon receptor activity
Oberg M, Bergander L, Hakansson H, Rannug U, Rannug A
TOXICOLOGICAL SCIENCES 2005;85(2):935-43

Subchronic toxicity of Baltic herring oil and its fractions in the rat (III) bone tissue composition and dimension, and ratio of n-6/n-3 fatty acids in serum phospholipids
Stern N, Korotkova M, Strandvik B, Oxlund H, Oberg M, Hakansson H, et al
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY 2005;96(6):453-64

Identification of factors that controls the CYP1A1 background activity in vitro
Oberg M, Bergander L, Hakansson H, Rannug U, Rannug A
TOXICOLOGY AND APPLIED PHARMACOLOGY 2004;197(3):216-216

Subchronic toxicity of Baltic herring oil and its fractions in the rat I: Fractionation and levels of organohalogen pollutants
Oberg M, Stern N, Jensen S, Wesen C, Haglund P, Casabona H, et al
PHARMACOLOGY & TOXICOLOGY 2002;91(5):220-31

Subchronic toxicity of Baltic herring oil and its fractions in the rat II: Clinical observations and toxicological parameters
Stern N, Oberg M, Casabona H, Trossvik C, Manzoor E, Johansson N, et al
PHARMACOLOGY & TOXICOLOGY 2002;91(5):232-44

Tissue distribution and half-lives of individual polychlorinated biphenyls and serum levels of 4-hydroxy-2,3,3 ',4 ',5-pentachlorobiphenyl in the rat
Oberg M, Sjodin A, Casabona H, Nordgren I, Klasson-wehler E, Hakansson H
TOXICOLOGICAL SCIENCES 2002;70(2):171-82

Multivariate modelling of polychlorinated biphenyl-induced CYP1A activity in the MH1C1 rat hepatoma cell line
Oberg M, Andersson Pl, Johansson N, Tysklind M, Hakansson H
ATLA-ALTERNATIVES TO LABORATORY ANIMALS 2001;29(3):291-5

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