Manuchehr Abedi Valugerdi

Publications
CV
Public outreach and news

Articles

Article: DERMATOLOGY. 2023;239(6):919-925

Safety and Efficacy of Autologous Melanocyte/Keratinocyte Transplantation in Patients with Refractory Stable Vitiligo.

Shahbazi A; Abedi Valugerdi M; Kazemi S; Samadi Kochaksaraei S; Naseh MH; Aghdami N; Sadeghi B
Article: JOURNAL OF PERSONALIZED MEDICINE. 2022;12(1):42

COL-3-Induced Molecular and Ultrastructural Alterations in K562 Cells.

Fares M; Oerther S; Hultenby K; Gubrianska D; Zhao Y; Abedi-Valugerdi M; Hassan M
Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2020;78:106042

The kidney injury caused by the onset of acute graft-versus-host disease is associated with down-regulation of αKlotho.

Amin R; He R; Gupta D; Zheng W; Burmakin M; Mohammad DK; DePierre JW; Sadeghi B; Olauson H; Wernerson A; El-Andaloussi S; Hassan M; Abedi-Valugerdi M
Article: PATHOGENS AND DISEASE. 2018;76(8)

Simultaneous formulation of influenza vaccine and chitosan nanoparticles within CpG oligodesoxi nucleotides leads to dose-sparing and protects against lethal challenge in the mouse model.

Sadati SF; Jamali A; Abdoli A; Abedi-Valugerdi M; Gholami S; Alipour S; Soleymani S; Kheiri MT; Atyabi F
Article: ONCOLOGY LETTERS. 2018;15(5):8157-8164

Downregulation of miR-1266-5P, miR-185-5P and miR-30c-2 in prostatic cancer tissue and cell lines.

Ostadrahimi S; Fayaz S; Parvizhamidi M; Abedi-Valugerdi M; Hassan M; Kadivar M; Teimoori-Toolabi L; Asgari M; Shahrokh H; Abolhasani M; Mahdian R; Fard-Esfahani P
Article: JOURNAL OF THEORETICAL BIOLOGY. 2018;442:1-10

Mathematical modeling of tumor-induced immunosuppression by myeloid-derived suppressor cells: Implications for therapeutic targeting strategies.

Shariatpanahi SP; Shariatpanahi SP; Madjidzadeh K; Hassan M; Abedi-Valugerdi M
Article: ANALYTICAL CHEMISTRY. 2017;89(14):7586-7592

Rapid and Robust Quantification of p-Xyleneselenocyanate in Plasma via Derivatization.

Zheng W; Benkessou F; Twelkmeyer B; Wang S; Ginman T; Ottosson H; Abedi-Valugerdi M; Subirana MA; Zhao Y; Hassan M
Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2017;47:173-181

Differential effects of low-dose fludarabine or 5-fluorouracil on the tumor growth and myeloid derived immunosuppression status of tumor-bearing mice.

Abedi-Valugerdi M; Zheng W; Benkessou F; Zhao Y; Hassan M
Article: PLOS ONE. 2017;12(11):e0187294

Flavin-containing monooxygenase 3 (FMO3) role in busulphan metabolic pathway.

El-Serafi I; Terelius Y; Abedi-Valugerdi M; Naughton S; Saghafian M; Moshfegh A; Mattsson J; Potácová Z; Hassan M
Article: JOURNAL OF NANOBIOTECHNOLOGY. 2016;14(1):82

Biodistribution of biodegradable polymeric nano-carriers loaded with busulphan and designed for multimodal imaging.

Asem H; Zhao Y; Ye F; Barrefelt Å; Abedi-Valugerdi M; El-Sayed R; El-Serafi I; Abu-Salah KM; Hamm J; Muhammed M; Hassan M
Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2016;40:41-49

Suppressive effects of low-dose 5-fluorouracil, busulfan or treosulfan on the expansion of circulatory neutrophils and myeloid derived immunosuppressor cells in tumor-bearing mice.

Abedi-Valugerdi M; Wolfsberger J; Pillai PR; Zheng W; Sadeghi B; Zhao Y; Hassan M
Article: TRANSPLANT IMMUNOLOGY. 2016;39:25-29

Evaluation of interleukin 12 and CD56+ lymphocyte cells in pediatric hematopoietic stem cell transplantation for early diagnosis of acute graft versus host disease.

Tootoonchian R; Pak F; Ardekani AM; Sehati N; Abedi-Valugerdi M; Kokhaei P
Article: PHARMACOGENOMICS JOURNAL. 2015;15(5):405-413

Cytochrome P450 2J2, a new key enzyme in cyclophosphamide bioactivation and a potential biomarker for hematological malignancies.

El-Serafi I; Fares M; Abedi-Valugerdi M; Afsharian P; Moshfegh A; Terelius Y; Potácová Z; Hassan M
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2015;463(3):268-274

DNA damage, lysosomal degradation and Bcl-xL deamidation in doxycycline- and minocycline-induced cell death in the K562 leukemic cell line.

Fares M; Abedi-Valugerdi M; Hassan M; Potácová Z
Article: CHEMOSPHERE. 2015;129:225-231

Complement activation is involved in the hepatic injury caused by high-dose exposure of mice to perfluorooctanoic acid.

Botelho SC; Saghafian M; Pavlova S; Hassan M; DePierre JW; Abedi-Valugerdi M
Article: IMMUNOLOGY LETTERS. 2015;163(2):193-198

Immunotoxicological effects of streptozotocin and alloxan: in vitro and in vivo studies.

Diab RAH; Fares M; Abedi-Valugerdi M; Kumagai-Braesch M; Holgersson J; Hassan M
Article: LEUKEMIA & LYMPHOMA. 2014;55(7):1618-1624

The nanoparticulate Quillaja saponin KGI exerts anti-proliferative effects by down-regulation of cell cycle molecules in U937 and HL-60 human leukemia cells.

Berenjian S; Hu K; Abedi-Valugerdi M; Hassan M; Bashir Hassan S; Morein B
Article: BIOMATERIALS. 2014;35(12):3885-3894

Biodegradable polymeric vesicles containing magnetic nanoparticles, quantum dots and anticancer drugs for drug delivery and imaging.

Ye F; Barrefelt A; Asem H; Abedi-Valugerdi M; El-Serafi I; Saghafian M; Abu-Salah K; Alrokayan S; Muhammed M; Hassan M
Article: CHEMOSPHERE. 2014;98:28-36

Tissue distribution of 35S-labelled perfluorobutanesulfonic acid in adult mice following dietary exposure for 1-5 days.

Bogdanska J; Sundström M; Bergström U; Borg D; Abedi-Valugerdi M; Bergman Å; DePierre J; Nobel S
Article: PLOS ONE. 2014;9(1):e86619

Cyclophosphamide alters the gene expression profile in patients treated with high doses prior to stem cell transplantation.

El-Serafi I; Abedi-Valugerdi M; Potácová Z; Afsharian P; Mattsson J; Moshfegh A; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2013;48(6):843-848

Omega-3 from fish oil augments GVHD through the enhancement of chemotherapy conditioning regimen and selective FoxP3 depletion.

Al Hashmi S; Sadeghi B; Hassan Z; Abedi-Valugerdi M; Lindskog M; Hassan M
Article: TOXICOLOGY LETTERS. 2013;219(1):1-7

Sub-acute, moderate-dose, but not short-term, low-dose dietary pre-exposure of mice to perfluorooctanoate aggravates concanavalin A-induced hepatitis.

Qazi MR; Hassan M; Nelson BD; Depierre JW; Abedi-Valugerdi M
Article: TOXICOLOGY LETTERS. 2013;217(1):67-74

Both sub-acute, moderate-dose and short-term, low-dose dietary exposure of mice to perfluorooctane sulfonate exacerbates concanavalin A-induced hepatitis.

Qazi MR; Hassan M; Nelson BD; DePierre JW; Abedi-Valugerdi M
Article: BONE MARROW TRANSPLANTATION. 2013;48(2):284-293

Early-phase GVHD gene expression profile in target versus non-target tissues: kidney, a possible target?

Sadeghi B; Al-Chaqmaqchi H; Al-Hashmi S; Brodin D; Hassan Z; Abedi-Valugerdi M; Moshfegh A; Hassan M
Article: PLOS ONE. 2013;8(4):e60367

The role of programmed cell death ligand-1 (PD-L1/CD274) in the development of graft versus host disease.

Al-Chaqmaqchi H; Sadeghi B; Abedi-Valugerdi M; Al-Hashmi S; Fares M; Kuiper R; Lundahl J; Hassan M; Moshfegh A
Article: FOOD AND CHEMICAL TOXICOLOGY. 2012;50(9):2955-2963

High-dose dietary exposure of mice to perfluorooctanoate or perfluorooctane sulfonate exerts toxic effects on myeloid and B-lymphoid cells in the bone marrow and these effects are partially dependent on reduced food consumption.

Qazi MR; Nelson BD; DePierre JW; Abedi-Valugerdi M
Article: TOXICOLOGY. 2011;284(1-3):54-62

Tissue distribution of ³⁵S-labelled perfluorooctane sulfonate in adult mice after oral exposure to a low environmentally relevant dose or a high experimental dose.

Bogdanska J; Borg D; Sundström M; Bergström U; Halldin K; Abedi-Valugerdi M; Bergman A; Nelson B; Depierre J; Nobel S
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2011;73(3):198-207

Characterization of the hepatic and splenic immune status and immunoglobulin synthesis in aged male mice lacking the peroxisome proliferator-activated receptor-alpha (PPARα).

Qazi MR; Abedi MR; Nelson BD; Depierre JW; Abedi-Valugerdi M
Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2010;10(11):1420-1427

Dietary exposure to perfluorooctanoate or perfluorooctane sulfonate induces hypertrophy in centrilobular hepatocytes and alters the hepatic immune status in mice.

Qazi MR; Abedi MR; Nelson BD; DePierre JW; Abedi-Valugerdi M
Article: TOXICOLOGY. 2010;267(1-3):132-139

28-Day dietary exposure of mice to a low total dose (7 mg/kg) of perfluorooctanesulfonate (PFOS) alters neither the cellular compositions of the thymus and spleen nor humoral immune responses: does the route of administration play a pivotal role in PFOS-induced immunotoxicity?

Qazi MR; Nelson BD; Depierre JW; Abedi-Valugerdi M
Article: CLINICAL AND DEVELOPMENTAL IMMUNOLOGY. 2010;2010:142943-13

Expansion and activation kinetics of immune cells during early phase of GVHD in mouse model based on chemotherapy conditioning.

Sadeghi B; Al-Hashmi S; Hassan Z; Rozell B; Concha H; Lundmark C; Grönvik K-O; Abedi-Valugerdi M; Hassan M
Article: TOXICOLOGY. 2009;262(3):207-214

High-dose, short-term exposure of mice to perfluorooctanesulfonate (PFOS) or perfluorooctanoate (PFOA) affects the number of circulating neutrophils differently, but enhances the inflammatory responses of macrophages to lipopolysaccharide (LPS) in a similar fashion.

Qazi MR; Bogdanska J; Butenhoff JL; Nelson BD; DePierre JW; Abedi-Valugerdi M
Article: TOXICOLOGY. 2009;260(1-3):68-76

The atrophy and changes in the cellular compositions of the thymus and spleen observed in mice subjected to short-term exposure to perfluorooctanesulfonate are high-dose phenomena mediated in part by peroxisome proliferator-activated receptor-alpha (PPARalpha).

Qazi MR; Xia Z; Bogdanska J; Chang S-C; Ehresman DJ; Butenhoff JL; Nelson BD; DePierre JW; Abedi-Valugerdi M
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2009;155(2):320-329

Isolation of murine intrahepatic immune cells employing a modified procedure for mechanical disruption and functional characterization of the B, T and natural killer T cells obtained.

Blom KG; Qazi MR; Matos JBN; Nelson BD; DePierre JW; Abedi-Valugerdi M
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2008;155(1):117-124

Mercury and silver induce B cell activation and anti-nucleolar autoantibody production in outbred mouse stocks: are environmental factors more important than the susceptibility genes in connection with autoimmunity?

Abedi-Valugerdi M
Article: BONE MARROW TRANSPLANTATION. 2008;42(12):807-818

GVHD after chemotherapy conditioning in allogeneic transplanted mice.

Sadeghi B; Aghdami N; Hassan Z; Forouzanfar M; Rozell B; Abedi-Valugerdi M; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2008;41(10):895-904

The effect of administration order of BU and CY on engraftment and toxicity in HSCT mouse model.

Sadeghi B; Jansson M; Hassan Z; Mints M; Hägglund H; Abedi-Valugerdi M; Hassan M
Article: EXPERIMENTAL HEMATOLOGY. 2006;34(1):115-121

Myeloablative and immunosuppressive properties of treosulfan in mice.

Sjöö F; Hassan Z; Abedi-Valugerdi M; Griskevicius L; Nilsson C; Remberger M; Aschan J; Concha H; Gaughan U; Hassan M
Article: EXPERIMENTAL HEMATOLOGY. 2005;33(11):1320-1328

Efficient gene transfer into primary human natural killer cells by retroviral transduction.

Guven H; Konstantinidis KV; Alici E; Aints A; Abedi-Valugerdi M; Christensson B; Ljunggren H-G; Dilber MS
Article: INFECTION AND IMMUNITY. 2005;73(11):7687-7696

Exposure to mycobacteria primes the immune system for evolutionarily diverse heat shock proteins.

Qazi KR; Qazi MR; Julián E; Singh M; Abedi-Valugerdi M; Fernández C
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2005;141(2):238-247

Bacterial lipopolysaccharide both renders resistant mice susceptible to mercury-induced autoimmunity and exacerbates such autoimmunity in susceptible mice.

Abedi-Valugerdi M; Nilsson C; Zargari A; Gharibdoost F; DePierre JW; Hassan M
Article: EXPERIMENTAL HEMATOLOGY. 2005;33(3):380-387

Effect of altering administration order of busulphan and cyclophosphamide on the myeloablative and immunosuppressive properties of the conditioning regimen in mice.

Nilsson C; Forsman J; Hassan Z; Abedi-Valugerdi M; O'Connor C; Concha H; Jansson M; Hassan M
Article: IMMUNOLOGY. 2005;114(3):428-437

Exposure to mercuric chloride during the induction phase and after the onset of collagen-induced arthritis enhances immune/autoimmune responses and exacerbates the disease in DBA/1 mice.

Hansson M; Djerbi M; Rabbani H; Mellstedt H; Gharibdoost F; Hassan M; Depierre JW; Abedi-Valugerdi M
Article: EXPERIMENTAL HEMATOLOGY. 2004;32(11):1064-1072

Visualization of 5T33 myeloma cells in the C57BL/KaLwRij mouse: establishment of a new syngeneic murine model of multiple myeloma.

Alici E; Konstantinidis KV; Aints A; Dilber MS; Abedi-Valugerdi M
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2004;59(5):469-477

Mercuric chloride induces a strong immune activation, but does not accelerate the development of dermal fibrosis in tight skin 1 mice.

Hansson M; Abedi-Valugerdi M
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;110(1):86-91

Mercury-induced renal immune complex deposits in young (NZB x NZW)F1 mice: characterization of antibodies/autoantibodies.

Abedi-Valugerdi M; Hu H; Möller G
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;131(3):405-414

Xenobiotic metal-induced autoimmunity: mercury and silver differentially induce antinucleolar autoantibody production in susceptible H-2s, H-2q and H-2f mice.

Hansson M; Abedi-Valugerdi M
Article: JOURNAL OF IMMUNOLOGY. 2003;170(4):2064-2073

Expression of the long form of human FLIP by retroviral gene transfer of hemopoietic stem cells exacerbates experimental autoimmune encephalomyelitis.

Djerbi M; Abdul-Majid K-B; Abedi-Valugerdi M; Olsson T; Harris RA; Grandien A
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2002;55(5):493-502

Spontaneous downregulation of antibody/autoantibody synthesis in susceptible mice upon chronic exposure to mercuric chloride is not owing to a general immunosuppression.

Roether S; Rabbani H; Mellstedt H; Abedi-Valugerdi M
Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2002;2(2-3):389-397

Potent suppression of the adaptive immune response in mice upon dietary exposure to the potent peroxisome proliferator, perfluorooctanoic acid.

Yang Q; Abedi-Valugerdi M; Xie Y; Zhao X-Y; Möller G; Nelson BD; DePierre JW
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;125(2):202-210

Analysis of mercury-induced immune activation in nonobese diabetic (NOD) mice.

Brenden N; Rabbani H; Abedi-Valugerdi M
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2001;54(1-2):190-197

Genetic control of resistance to mercury-induced immune/autoimmune activation.

Abedi-Valugerdi M; Hansson M; Möller G
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2001;53(1):32-39

Immune complex-induced chronic and intense IL-4 independent IgG1-rheumatoid factor production in NZB mice.

Nordström E; Abedi-Valugerdi M; Möller E
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2000;52(5):477-482

Longevity of immune complexes and abnormal germinal centre formation in NZB mice.

Nordström E; Abedi-Valugerdi M; Möller E
Article: INTERNATIONAL IMMUNOLOGY. 2000;12(10):1425-1430

Contribution of H-2 and non-H-2 genes in the control of mercury-induced autoimmunity.

Abedi-Valugerdi M; Möller G
Article: INTERNATIONAL IMMUNOLOGY. 1999;11(4):605-615

Mercury-induced anti-nucleolar autoantibodies can transgress the membrane of living cells in vivo and in vitro.

Abedi-Valugerdi M; Hu H; Möller G
Article: IMMUNOLOGY. 1999;96(3):348-357

Mechanism of mercury-induced autoimmunity: both T helper 1- and T helper 2-type responses are involved.

Hu H; Möller G; Abedi-Valugerdi M
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1998;48(5):515-521

Non-responsiveness to mercury-induced autoimmunity in resistant DBA/2 mice is not due to immunosuppression or biased Th1-type response.

Hu H; Möller G; Abedi-Valugerdi M
Article: JOURNAL OF AUTOIMMUNITY. 1998;11(2):131-140

Induction of IgG rheumatoid factor (RF) production by antibody-antibody (RF-like) immune complexes: the role of T cells, complement and Fc gamma receptors.

Nordström E; Möller E; Abedi-Valugerdi M
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1997;45(3):231-239

Polyreactive binding of antibodies generated by polyclonal B cell activation. I. Polyreactivity could be caused by differential glycosylation of immunoglobulins.

Fernández C; Alarcón-Riquelme ME; Abedi-Valugerdi M; Sverremark E; Cortes V
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1996;44(5):470-477

Binding specificities of a polyreactive and a monoreactive human monoclonal IgG rheumatoid factor: role of oligosaccharides.

al-Balaghi S; Abedi-Valugerdi M; Möller E
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1996;26(7):1519-1526

Mercury induces polyclonal B cell activation, autoantibody production and renal immune complex deposits in young (NZB x NZW)F1 hybrids.

al-Balaghi S; Möller E; Möller G; Abedi-Valugerdi M
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1995;41(6):575-582

Human IgG rheumatoid factors and RF-like immune complexes induce IgG1 rheumatoid factor production in mice.

Abedi-Valugerdi M; Ridderstad A; al-Balaghi S; Möller E
Article: INTERNATIONAL IMMUNOLOGY. 1995;7(3):459-469

Differential sensitivity to transforming growth factor (TGF)-beta of CBA and of CBA/N B cells demonstrates that the IgG2b inducing factor in synovial fluid from rheumatoid arthritis patients is not identical to TGF-beta.

Ridderstad A; Lettesjö H; Abedi-Valugerdi M; Möller E
Show more

All other publications

Review: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2021;25(18):8602-8614

Advanced therapeutic modalities in hepatocellular carcinoma: Novel insights.

Shokoohian B; Negahdari B; Aboulkheyr Es H; Abedi-Valugerdi M; Baghaei K; Agarwal T; Maiti TK; Hassan M; Najimi M; Vosough M
Editorial comment: HAEMATOLOGICA. 2014;99(7):1124-1127

Hematologic malignancies in elderly patients.

Hassan M; Abedi-Valugerdi M

Employments

Affiliated to Research, Department of Laboratory Medicine, Karolinska Institutet, 2024-2025
Research Coordinator, Department of Laboratory Medicine, Karolinska Institutet, 2012-2023

Degrees and Education

Docent, Stockholms universitet, 1999

Articles

All other publications

Employments

Degrees and Education

News from KI

Events from KI