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About me

My research interest lies in obtaining a deeper understanding of the regional and temporal evolution of Alzheimer’s disease pathology with the use of advanced neuroimaging techniques. As a physician, I am particularly interested in the incorporation of validated biomarkers to clinical practice for the purpose of diagnosis at the early stages of the disease, as well as evaluation of therapeutic efficacy once disease-modifying treatments become available. I am currently a fourth year Ph.D. candidate under the supervision of Prof. Agneta Nordberg (Karolinska Institutet), Dr. Stephen F. Carter (University of Manchester), Prof. Ove Almkvist (Karolinska Institutet) and Dr. Laure Saint-Aubert (Karolinska Institutet).

Education

July, 2012. License to practice medicine in Sweden (Socialstyrelsen).

July, 2011. Doctor of Medicine (M.D.), University of Patras, Patras, Greece.

Documents

Links

Publications

A Cross-Validation of FDG- and Amyloid-PET Biomarkers in Mild Cognitive Impairment for the Risk Prediction to Dementia due to Alzheimer's Disease in a Clinical Setting
Iaccarino L, Chiotis K, Alongi P, Almkvist O, Wall A, Cerami C, et al
Journal of Alzheimer's disease : JAD 2017;59(2):603-614

Clinical validity of increased cortical uptake of amyloid ligands on PET as a biomarker for Alzheimer's disease in the context of a structured 5-phase development framework
Chiotis K, Saint-aubert L, Boccardi M, Gietl A, Picco A, Varrone A, et al
Neurobiology of aging 2017;52():214-227

Comparability of [F]THK5317 and [C]PIB blood flow proxy images with [F]FDG positron emission tomography in Alzheimer's disease
Rodriguez-vieitez E, Leuzy A, Chiotis K, Saint-aubert L, Wall A, Nordberg A
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2017;37(2):740-749

Longitudinal changes of tau PET imaging in relation to hypometabolism in prodromal and Alzheimer's disease dementia
Chiotis K, Saint-aubert L, Rodriguez-vieitez E, Leuzy A, Almkvist O, Savitcheva I, et al
Molecular psychiatry 2017;():-

Strategic roadmap for an early diagnosis of Alzheimer's disease based on biomarkers
Frisoni Gb, Boccardi M, Barkhof F, Blennow K, Cappa S, Chiotis K, et al
The Lancet. Neurology 2017;16(8):661-676

Tau PET imaging: present and future directions
Saint-aubert L, Lemoine L, Chiotis K, Leuzy A, Rodriguez-vieitez E, Nordberg A
Molecular neurodegeneration 2017;12(1):19-

Comparison of Early-Phase 11C-Deuterium-l-Deprenyl and 11C-Pittsburgh Compound B PET for Assessing Brain Perfusion in Alzheimer Disease
Rodriguez-vieitez E, Carter Sf, Chiotis K, Saint-aubert L, Leuzy A, Schöll M, et al
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2016;57(7):1071-7

COMPARISON OF EARLY-PHASE (S)-[18F]THK5117 AND [11C]PIB PET IMAGING TO ASSESS BRAIN PERFUSION IN ALZHEIMER'S DISEASE
Rodriguez-vieitez E, Leuzy A, Chiotis K, Saint-aubert L, Nordberg A
NEUROBIOLOGY OF AGING 2016;:S21-S21

Diverging longitudinal changes in astrocytosis and amyloid PET in autosomal dominant Alzheimer's disease
Rodriguez-vieitez E, Saint-aubert L, Carter Sf, Almkvist O, Farid K, Schöll M, et al
Brain : a journal of neurology 2016;139(Pt 3):922-36

Imaging in-vivo tau pathology in Alzheimer's disease with THK5317 PET in a multimodal paradigm
Chiotis K, Saint-aubert L, Savitcheva I, Jelic V, Andersen P, Jonasson M, et al
European journal of nuclear medicine and molecular imaging 2016;43(9):1686-99

IMPROVED CONCORDANCE BETWEEN [11C]PIB PET AND CSF A beta 42 USING A beta 42/A beta 40: FINDINGS FROM A MULTICENTRE EUROPEAN MEMORY CLINIC POPULATION
Leuzy A, Chiotis K, Pannee J, Hasselbalch S, Rinne J, Castelo-branco M, et al
NEUROBIOLOGY OF AGING 2016;:S18-S18

Pittsburgh compound B imaging and cerebrospinal fluid amyloid-β in a multicentre European memory clinic study
Leuzy A, Chiotis K, Hasselbalch Sg, Rinne Jo, De Mendonça A, Otto M, et al
Brain : a journal of neurology 2016;139(Pt 9):2540-53

Regional tau deposition measured by [F]THK5317 positron emission tomography is associated to cognition via glucose metabolism in Alzheimer's disease
Saint-aubert L, Almkvist O, Chiotis K, Almeida R, Wall A, Nordberg A
Alzheimer's research & therapy 2016;8(1):38-

Supervised Cluster Analysis for Automatic Extraction of Reference Region in Dynamic [F-18]THK5317 PET
Jonasson M, Wall A, Chiotis K, Heurling K, Saint-aubert L, Antoni G, et al
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 2016;:S25-S25

TAU PET IMAGING IN NEURODEGENERATIVE TAUOPATHIES - A MULTIMODAL PARADIGM
Chiotis K, Saint-aubert L, Leuzy A, Rodriguez-vieitez E, Nordberg A
NEUROBIOLOGY OF AGING 2016;:S29-S29

Tracer Kinetic Analysis of (S)-¹⁸F-THK5117 as a PET Tracer for Assessing Tau Pathology
Jonasson M, Wall A, Chiotis K, Saint-aubert L, Wilking H, Sprycha M, et al
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2016;57(4):574-81

Amyloid PET in European and North American cohorts; and exploring age as a limit to clinical use of amyloid imaging
Chiotis K, Carter Sf, Farid K, Savitcheva I, Nordberg A, Diagnostic Molecular Imaging (dimi) Network And The Alzheimer’s Disease Neuroimaging Initiative
European journal of nuclear medicine and molecular imaging 2015;42(10):1492-506

Concordance and Diagnostic Accuracy of [11C]PIB PET and Cerebrospinal Fluid Biomarkers in a Sample of Patients with Mild Cognitive Impairment and Alzheimer's Disease
Leuzy A, Carter Sf, Chiotis K, Almkvist O, Wall A, Nordberg A
Journal of Alzheimer's disease : JAD 2015;45(4):1077-88

Tracer kinetic analysis of (S)-[F-18]THK5117 as a PET tracer for tau pathology
Lubberink M, Jonasson M, Wall A, Chiotis K, Saint-aubert L, Eriksson J, et al
JOURNAL OF NUCLEAR MEDICINE 2015;56(3):-

Role of anthropometric characteristics in idiopathic carpal tunnel syndrome
Chiotis K, Dimisianos N, Rigopoulou A, Chrysanthopoulou A, Chroni E
Archives of physical medicine and rehabilitation 2013;94(4):737-44

Idiopathic carpal tunnel syndrome: is it really idiopathic? The role of anthropometric hand measurements
Chiotis K, Dimisianos N, Rigopoulou A, Chrysanthopoulou A, Chroni E
EUROPEAN JOURNAL OF NEUROLOGY 2012;:778-778

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