Katarina Varnäs

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Articles

Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2023;26(4):241-248

Associations Between Cognition and Serotonin 1B Receptor Availability in Healthy Volunteers: A [11C]AZ10419369 Positron Emission Tomography Study.

Tangen Ä; Veldman ER; Svensson J; Tiger M; Nord M; Sorjonen K; Andersson M; Plavén-Sigray P; Varrone A; Halldin C; Varnäs K; Borg J; Lundberg J
Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2022;42(4):630-641

Serotonin 1B receptor density mapping of the human brainstem using positron emission tomography and autoradiography.

Veldman ER; Varrone A; Varnäs K; Svedberg MM; Cselényi Z; Tiger M; Gulyás B; Halldin C; Lundberg J
Article: JOURNAL OF AFFECTIVE DISORDERS. 2021;294:645-651

A positron emission tomography study of the serotonin1B receptor effect of electroconvulsive therapy for severe major depressive episodes.

Tiger M; Gärde M; Tateno A; Matheson GJ; Sakayori T; Nogami T; Moriya H; Varnäs K; Arakawa R; Okubo Y
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2021;64(16):12003-12021

[11C]CHDI-626, a PET Tracer Candidate for Imaging Mutant Huntingtin Aggregates with Reduced Binding to AD Pathological Proteins.

Liu L; Johnson PD; Prime ME; Khetarpal V; Lee MR; Brown CJ; Chen X; Clark-Frew D; Coe S; Conlon M; Davis R; Ensor S; Esposito S; Moren AF; Gai X; Green S; Greenaway C; Haber J; Halldin C; Hayes S; Herbst T; Herrmann F; Heßmann M; Hsai MM; Kotey A; Mangette JE; Mills MR; Monteagudo E; Nag S; Nibbio M; Orsatti L; Schaertl S; Scheich C; Sproston J; Stepanov V; Varnäs K; Varrone A; Wityak J; Mrzljak L; Munoz-Sanjuan I; Bard JA; Dominguez C
Article: NEURO-ONCOLOGY. 2021;23(4):687-696

Brain exposure of the ATM inhibitor AZD1390 in humans-a positron emission tomography study.

Jucaite A; Stenkrona P; Cselényi Z; De Vita S; Buil-Bruna N; Varnäs K; Savage A; Varrone A; Johnström P; Schou M; Davison C; Sykes A; Pilla Reddy V; Hoch M; Vazquez-Romero A; Moein MM; Halldin C; Merchant MS; Pass M; Farde L
Article: CLINICAL CANCER RESEARCH. 2021;27(1):189-201

Preclinical Comparison of the Blood-brain barrier Permeability of Osimertinib with Other EGFR TKIs.

Colclough N; Chen K; Johnström P; Strittmatter N; Yan Y; Wrigley GL; Schou M; Goodwin R; Varnäs K; Adua SJ; Zhao M; Nguyen DX; Maglennon G; Barton P; Atkinson J; Zhang L; Janefeldt A; Wilson J; Smith A; Takano A; Arakawa R; Kondrashov M; Malmquist J; Revunov E; Vazquez-Romero A; Moein MM; Windhorst AD; Karp NA; Finlay MRV; Ward RA; Yates JWT; Smith PD; Farde L; Cheng Z; Cross DAE
Article: BRITISH JOURNAL OF ANAESTHESIA. 2021;126(1):238-244

Effects of sevoflurane anaesthesia on radioligand binding to monoamine oxidase-B in vivo.

Varnäs K; Finnema SJ; Johnström P; Arakawa R; Halldin C; Eriksson LI; Farde L
Article: ACS CHEMICAL NEUROSCIENCE. 2020;11(24):4398-4404

Synthesis and Autoradiography of Novel F-18 Labeled Reversible Radioligands for Detection of Monoamine Oxidase B.

Nag S; Jia Z; Svedberg M; Jackson A; Ahmad R; Luthra S; Varnäs K; Farde L; Halldin C
Article: MOLECULAR BRAIN. 2020;13(1):164

Altered striatal dopamine levels in Parkinson's disease VPS35 D620N mutant transgenic aged mice.

Vanan S; Zeng X; Chia SY; Varnäs K; Jiang M; Zhang K; Saw WT; Padmanabhan P; Yu W-P; Zhou Z-D; Halldin C; Gulyás B; Tan E-K; Zeng L
Article: SYNAPSE. 2020;74(10):e22157

Autoradiographic mapping of synaptic vesicle glycoprotein 2A in non-human primate and human brain.

Varnäs K; Stepanov V; Halldin C
Article: ACS CHEMICAL NEUROSCIENCE. 2020;11(7):1048-1057

Synthesis, Biodistribution, and Radiation Dosimetry of a Novel mGluR5 Radioligand: 18F-AZD9272.

Nag S; Varnäs K; Arakawa R; Jahan M; Schou M; Farde L; Halldin C
Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2020;40(4):799-807

A PET study in healthy subjects of brain exposure of 11C-labelled osimertinib - A drug intended for treatment of brain metastases in non-small cell lung cancer.

Varrone A; Varnäs K; Jucaite A; Cselényi Z; Johnström P; Schou M; Vazquez-Romero A; Moein MM; Halldin C; Brown AP; Vishwanathan K; Farde L
Article: NEUROPHARMACOLOGY. 2020;162:107809

The pro-psychotic metabotropic glutamate receptor compounds fenobam and AZD9272 share binding sites with monoamine oxidase-B inhibitors in humans.

Varnäs K; Cselényi Z; Arakawa R; Nag S; Stepanov V; Moein MM; Johnström P; Kingston L; Elmore CS; Halldin C; Farde L
Article: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2019;29(13):1624-1627

Synthesis and preclinical evaluation of [18F]FSL25.1188, a reversible PET radioligand for monoamine oxidase-B.

Dahl K; Bernard-Gauthier V; Nag S; Varnäs K; Narayanaswami V; Mahdi Moein M; Arakawa R; Vasdev N; Halldin C
Article: BRAIN RESEARCH. 2019;1711:140-145

In vitro phosphodiesterase 10A (PDE10A) binding in whole hemisphere human brain using the PET radioligand [18F]MNI-659.

Svedberg MM; Varnäs K; Varrone A; Mitsios N; Mulder J; Gulyás B; Beaumont V; Munoz-Sanjuan I; Zaleska MM; Schmidt CJ; Halldin C; Mrzljak L
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2019;46(2):367-375

PET imaging of [11C]PBR28 in Parkinson's disease patients does not indicate increased binding to TSPO despite reduced dopamine transporter binding.

Varnäs K; Cselényi Z; Jucaite A; Halldin C; Svenningsson P; Farde L; Varrone A
Article: SCIENCE ADVANCES. 2018;4(6):eaat1719

The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models.

Durant ST; Zheng L; Wang Y; Chen K; Zhang L; Zhang T; Yang Z; Riches L; Trinidad AG; Fok JHL; Hunt T; Pike KG; Wilson J; Smith A; Colclough N; Reddy VP; Sykes A; Janefeldt A; Johnström P; Varnäs K; Takano A; Ling S; Orme J; Stott J; Roberts C; Barrett I; Jones G; Roudier M; Pierce A; Allen J; Kahn J; Sule A; Karlin J; Cronin A; Chapman M; Valerie K; Illingworth R; Pass M
Article: NEUROPHARMACOLOGY. 2018;135:455-463

The metabotropic glutamate receptor 5 radioligand [11C]AZD9272 identifies unique binding sites in primate brain.

Varnäs K; Juréus A; Finnema SJ; Johnström P; Raboisson P; Amini N; Takano A; Stepanov V; Halldin C; Farde L
Article: ACS CHEMICAL NEUROSCIENCE. 2018;9(5):906-911

Development of [ Carbonyl-11C]AZ13198083, a Novel Histamine Type-3 Receptor Radioligand with Favorable Kinetics.

Dahl K; Nakao R; Amini N; Moein MM; Finnema S; Malmquist J; Varnäs K; Schou M
Article: ACS CHEMICAL NEUROSCIENCE. 2018;9(2):224-229

Discovery of a Novel Muscarinic Receptor PET Radioligand with Rapid Kinetics in the Monkey Brain.

Malmquist J; Varnäs K; Svedberg M; Vallée F; Albert JS; Finnema SJ; Schou M
Article: PSYCHIATRY RESEARCH-NEUROIMAGING. 2017;267:15-21

Associations between cognition and serotonin receptor 1B binding in patients with major depressive disorder - A pilot study.

Tangen Ä; Borg J; Tiger M; Varnäs K; Sorjonen K; Lindefors N; Halldin C; Lundberg J
Article: JOURNAL OF NUCLEAR MEDICINE. 2017;58(4):617-622

Longitudinal Small-Animal PET Imaging of the zQ175 Mouse Model of Huntington Disease Shows In Vivo Changes of Molecular Targets in the Striatum and Cerebral Cortex.

Häggkvist J; Tóth M; Tari L; Varnäs K; Svedberg M; Forsberg A; Nag S; Dominguez C; Munoz-Sanjuan I; Bard J; Wityak J; Varrone A; Halldin C; Mrzljak L
Article: PSYCHOPHARMACOLOGY. 2017;234(4):707-716

GABAA receptor occupancy by subtype selective GABAAα2,3 modulators: PET studies in humans.

Jucaite A; Cselényi Z; Lappalainen J; McCarthy DJ; Lee C-M; Nyberg S; Varnäs K; Stenkrona P; Halldin C; Cross A; Farde L
Article: CLINICAL CANCER RESEARCH. 2016;22(20):5130-5140

Preclinical Comparison of Osimertinib with Other EGFR-TKIs in EGFR-Mutant NSCLC Brain Metastases Models, and Early Evidence of Clinical Brain Metastases Activity.

Ballard P; Yates JWT; Yang Z; Kim D-W; Yang JC-H; Cantarini M; Pickup K; Jordan A; Hickey M; Grist M; Box M; Johnström P; Varnäs K; Malmquist J; Thress KS; Jänne PA; Cross D
Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2016;358(3):464-471

Integrated Strategy for Use of Positron Emission Tomography in Nonhuman Primates to Confirm Multitarget Occupancy of Novel Psychotropic Drugs: An Example with AZD3676.

Varnäs K; Juréus A; Johnström P; Ahlgren C; Schött P; Schou M; Gruber S; Jerning E; Malmborg J; Halldin C; Afzelius L; Farde L
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2016;19(8):pyw023

Neurokinin-3 Receptor Binding in Guinea Pig, Monkey, and Human Brain: In Vitro and in Vivo Imaging Using the Novel Radioligand, [18F]Lu AF10628.

Varnäs K; Finnema SJ; Stepanov V; Takano A; Tóth M; Svedberg M; Møller Nielsen S; Khanzhin NA; Juhl K; Bang-Andersen B; Halldin C; Farde L
Article: NEUROIMAGE. 2016;133:313-320

Mapping the distribution of serotonin transporter in the human brainstem with high-resolution PET: Validation using postmortem autoradiography data.

Fazio P; Schain M; Varnäs K; Halldin C; Farde L; Varrone A
Article: ACS CHEMICAL NEUROSCIENCE. 2016;7(2):177-184

Discovery and Preclinical Validation of [(11)C]AZ13153556, a Novel Probe for the Histamine Type 3 Receptor.

Schou M; Varnäs K; Jureus A; Ahlgren C; Malmquist J; Häggkvist J; Tari L; Wesolowski SS; Throner SR; Brown DG; Nilsson M; Johnström P; Finnema SJ; Nakao R; Amini N; Takano A; Farde L
Article: NEUROPHARMACOLOGY. 2016;101:519-530

A PET study comparing receptor occupancy by five selective cannabinoid 1 receptor antagonists in non-human primates.

Hjorth S; Karlsson C; Jucaite A; Varnäs K; Wählby Hamrén U; Johnström P; Gulyás B; Donohue SR; Pike VW; Halldin C; Farde L
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2015;58(20):8200-8215

Discovery and Evaluation of Clinical Candidate AZD3759, a Potent, Oral Active, Central Nervous System-Penetrant, Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor.

Zeng Q; Wang J; Cheng Z; Chen K; Johnström P; Varnäs K; Li DY; Yang ZF; Zhang X
Article: BRAIN. 2015;138(Pt 9):2687-2700

Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson's disease.

Jucaite A; Svenningsson P; Rinne JO; Cselényi Z; Varnäs K; Johnström P; Amini N; Kirjavainen A; Helin S; Minkwitz M; Kugler AR; Posener JA; Budd S; Halldin C; Varrone A; Farde L
Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2015;80(1):116-127

Estimation of drug receptor occupancy when non-displaceable binding differs between brain regions – extending the simplified reference tissue model.

Kågedal M; Varnäs K; Hooker AC; Karlsson MO
Article: NUCLEAR MEDICINE AND BIOLOGY. 2015;42(6):555-560

Development of rapid multistep carbon-11 radiosynthesis of the myeloperoxidase inhibitor AZD3241 to assess brain exposure by PET microdosing.

Johnström P; Bergman L; Varnäs K; Malmquist J; Halldin C; Farde L
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2015;18(10):pyv036

Large Variation in Brain Exposure of Reference CNS Drugs: a PET Study in Nonhuman Primates.

Schou M; Varnäs K; Lundquist S; Nakao R; Amini N; Takano A; Finnema SJ; Halldin C; Farde L
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2014;18(3):pyu081

Amphetamine decreases α2C-adrenoceptor binding of [11C]ORM-13070: a PET study in the primate brain.

Finnema SJ; Hughes ZA; Haaparanta-Solin M; Stepanov V; Nakao R; Varnäs K; Varrone A; Arponen E; Marjamäki P; Pohjanoksa K; Vuorilehto L; Babalola PA; Solin O; Grimwood S; Sallinen J; Farde L; Scheinin M; Halldin C
Article: NEUROINFORMATICS. 2014;12(4):551-562

Evaluation of two automated methods for PET region of interest analysis.

Schain M; Varnäs K; Cselényi Z; Halldin C; Farde L; Varrone A
Article: MOLECULAR IMAGING AND BIOLOGY. 2014;16(2):173-179

Synthesis, radiolabeling, and in vivo pharmacokinetic evaluation of the amyloid beta radioligand [11C]AZD4694 in nonhuman primates.

Schou M; Varnäs K; Sandell J; Johnström P; Cselenyi Z; Svensson S; Nakao R; Amini N; Bergman L; Sumic A; Gulyas B; Lindström-Böö E; Halldin C; Farde L
Article: NEUROBIOLOGY OF AGING. 2014;35(4):867-875

Positron emission tomography imaging of 5-hydroxytryptamine1B receptors in Parkinson's disease.

Varrone A; Svenningsson P; Forsberg A; Varnäs K; Tiger M; Nakao R; Halldin C; Nilsson L-G; Farde L
Article: SYNAPSE. 2014;68(3):89-97

Low brain CB1 receptor occupancy by a second generation CB1 receptor antagonist TM38837 in comparison with rimonabant in nonhuman primates: a PET study.

Takano A; Gulyás B; Varnäs K; Little PB; Noerregaard PK; Jensen NO; Elling CE; Halldin C
Article: NEUROSCIENCE LETTERS. 2014;559:163-168

Antidepressant effects on serotonin 1A/1B receptors in the rat brain using a gene x environment model.

Shrestha SS; Pine DS; Luckenbaugh DA; Varnäs K; Henter ID; Innis RB; Mathé AA; Svenningsson P
Article: NEUROIMAGE. 2013;82:160-169

A positron emission tomography study in healthy volunteers to estimate mGluR5 receptor occupancy of AZD2066 - estimating occupancy in the absence of a reference region.

Kågedal M; Cselényi Z; Nyberg S; Raboisson P; Ståhle L; Stenkrona P; Varnäs K; Halldin C; Hooker AC; Karlsson MO
Article: NUCLEAR MEDICINE AND BIOLOGY. 2013;40(6):747-754

Radiosynthesis and evaluation of new α1-adrenoceptor antagonists as PET radioligands for brain imaging.

Airaksinen AJ; Finnema SJ; Balle T; Varnäs K; Bang-Andersen B; Gulyás B; Farde L; Halldin C
Article: CEPHALALGIA. 2013;33(10):853-860

A PET study with [11C]AZ10419369 to determine brain 5-HT1B receptor occupancy of zolmitriptan in healthy male volunteers.

Varnäs K; Jučaite A; McCarthy DJ; Stenkrona P; Nord M; Halldin C; Farde L; Kanes S
Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2013;33(7):1058-1065

Arterial input function derived from pairwise correlations between PET-image voxels.

Schain M; Benjaminsson S; Varnäs K; Forsberg A; Halldin C; Lansner A; Farde L; Varrone A
Article: NUCLEAR MEDICINE AND BIOLOGY. 2013;40(3):410-414

Radiolabeling of the cannabinoid receptor agonist AZD1940 with carbon-11 and PET microdosing in non-human primate.

Schou M; Varnäs K; Jucaite A; Gulyás B; Halldin C; Farde L
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2013;40(4):580-593

Low background and high contrast PET imaging of amyloid-β with [11C]AZD2995 and [11C]AZD2184 in Alzheimer's disease patients.

Forsberg A; Juréus A; Cselényi Z; Eriksdotter M; Freund-Levi Y; Jeppsson F; Swahn B-M; Sandell J; Julin P; Schou M; Andersson J; Johnström P; Varnäs K; Halldin C; Farde L; Svensson S
Article: EJNMMI RESEARCH. 2012;2:15

Kinetic analysis and test-retest variability of the radioligand [11C](R)-PK11195 binding to TSPO in the human brain - a PET study in control subjects.

Jučaite A; Cselényi Z; Arvidsson A; Ahlberg G; Julin P; Varnäs K; Stenkrona P; Andersson J; Halldin C; Farde L
Article: JOURNAL OF NUCLEAR MEDICINE. 2012;53(3):415-424

Clinical validation of 18F-AZD4694, an amyloid-β-specific PET radioligand.

Cselényi Z; Jönhagen ME; Forsberg A; Halldin C; Julin P; Schou M; Johnström P; Varnäs K; Svensson S; Farde L
Article: PSYCHOPHARMACOLOGY. 2011;213(2-3):533-545

Dose-dependent binding of AZD3783 to brain 5-HT1B receptors in non-human primates and human subjects: a positron emission tomography study with [11C]AZ10419369.

Varnäs K; Nyberg S; Karlsson P; Pierson ME; Kågedal M; Cselényi Z; McCarthy D; Xiao A; Zhang M; Halldin C; Farde L
Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2011;31(1):113-123

Quantitative analysis of [11C]AZ10419369 binding to 5-HT1B receptors in human brain.

Varnäs K; Nyberg S; Halldin C; Varrone A; Takano A; Karlsson P; Andersson J; McCarthy D; Smith M; Pierson ME; Söderström J; Farde L
Article: SYNAPSE. 2010;64(10):733-741

Radiosynthesis of the candidate beta-amyloid radioligand [(11)C]AZD2184: Positron emission tomography examination and metabolite analysis in cynomolgus monkeys.

Andersson JD; Varnäs K; Cselényi Z; Gulyás B; Wensbo D; Finnema SJ; Swahn B-M; Svensson S; Nyberg S; Farde L; Halldin C
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2009;36(11):1859-1863

Detection of amyloid in Alzheimer's disease with positron emission tomography using [11C]AZD2184.

Nyberg S; Jönhagen ME; Cselényi Z; Halldin C; Julin P; Olsson H; Freund-Levi Y; Andersson J; Varnäs K; Svensson S; Farde L
Article: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2009;19(21):6209-6212

Synthesis and in vitro autoradiographic evaluation of a novel high-affinity radioiodinated ligand for imaging brain cannabinoid subtype-1 receptors.

Donohue SR; Varnäs K; Jia Z; Gulyás B; Pike VW; Halldin C
Article: NEUROIMAGE. 2009;47(1):213-219

Local and covariate-modulated false discovery rates applied in neuroimaging.

Lawyer G; Ferkingstad E; Nesvåg R; Varnäs K; Agartz I
Article: CEREBELLUM. 2009;8(1):52-60

Grey and white matter proportional relationships in the cerebellar vermis altered in schizophrenia.

Lawyer G; Nesvåg R; Varnäs K; Okugawa G; Agartz I
Article: PSYCHIATRY RESEARCH. 2008;164(3):254-264

Investigating possible subtypes of schizophrenia patients and controls based on brain cortical thickness.

Lawyer G; Nesvåg R; Varnäs K; Frigessi A; Agartz I
Article: NEUROIMAGE. 2008;41(3):1075-1085

[11C]AZ10419369: a selective 5-HT1B receptor radioligand suitable for positron emission tomography (PET). Characterization in the primate brain.

Pierson ME; Andersson J; Nyberg S; McCarthy DJ; Finnema SJ; Varnäs K; Takano A; Karlsson P; Gulyás B; Medd AM; Lee C-M; Powell ME; Heys JR; Potts W; Seneca N; Mrzljak L; Farde L; Halldin C
Article: SCHIZOPHRENIA RESEARCH. 2008;98(1-3):16-28

Regional thinning of the cerebral cortex in schizophrenia: effects of diagnosis, age and antipsychotic medication.

Nesvåg R; Lawyer G; Varnäs K; Fjell AM; Walhovd KB; Frigessi A; Jönsson EG; Agartz I
Article: PSYCHIATRY AND CLINICAL NEUROSCIENCES. 2007;61(3):326-329

Cerebellar volumes in men with schizophrenia and alcohol dependence.

Varnäs K; Okugawa G; Hammarberg A; Nesvåg R; Rimol LM; Franck J; Agartz I
Article: SYNAPSE. 2005;56(1):21-28

Regional expression of 5-HT1B receptor mRNA in the human brain.

Varnäs K; Hurd YL; Hall H
Article: NEUROSCIENCE LETTERS. 2004;367(3):313-316

Distribution of 5-HT7 receptors in the human brain: a preliminary autoradiographic study using [3H]SB-269970.

Varnäs K; Thomas DR; Tupala E; Tiihonen J; Hall H
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2003;13(4):228-234

Distribution of 5-HT4 receptors in the postmortem human brain--an autoradiographic study using [125I]SB 207710.

Varnäs K; Halldin C; Pike VW; Hall H
Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2003;304(1):81-87

Pharmacological characterization of N,N-dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a ligand of the serotonin transporter with high affinity and selectivity.

Chalon S; Tarkiainen J; Garreau L; Hall H; Emond P; Vercouillie J; Farde L; Dasse P; Varnas K; Besnard J-C; Halldin C; Guilloteau D
Article: NUCLEAR MEDICINE AND BIOLOGY. 2002;29(4):389-398

Synthesis and biological evaluation of technetium(III) mixed-ligand complexes with high affinity for the cerebral 5-HT(1A) receptor and the alpha1-adrenergic receptor.

Drews A; Pietzsch H-J; Syhre R; Seifert S; Varnäs K; Hall H; Halldin C; Kraus W; Karlsson P; Johnsson C; Spies H; Johannsen B
Article: NUCLEAR MEDICINE AND BIOLOGY. 2002;29(4):375-387

Synthesis, biological and autoradiographic evaluation of a novel Tc-99m radioligand derived from WAY 100635 with high affinity for the 5-HT(1A) receptor and the alpha1-adrenergic receptor.

Heimbold I; Drews A; Kretzschmar M; Varnäs K; Hall H; Halldin C; Syhre R; Kraus W; Pietzsch H-J; Seifert S; Brust P; Johannsen B
Article: BIOLOGIA FUTURA. 2002;53(1-2):59-66

Autoradiographic evaluation of [11C]vinpocetine binding in the human postmortem brain.

Hall H; Varnäs K; Sandell J; Halldin C; Farde L; Vas A; Kárpáti E; Gulyás B
Article: BRAIN RESEARCH. 2001;915(1):47-57

Autoradiographic mapping of 5-HT(1B) and 5-HT(1D) receptors in the post mortem human brain using [(3)H]GR 125743.

Varnäs K; Hall H; Bonaventure P; Sedvall G
Article: NUCLEAR MEDICINE AND BIOLOGY. 2001;28(2):177-185

New halogenated [11C]WAY analogues, [11C]6FPWAY and [11C]6BPWAY--radiosynthesis and assessment as radioligands for the study of brain 5-HT1A receptors in living monkey.

Sandell J; Halldin C; Pike VW; Chou YH; Varnäs K; Hall H; Marchais S; Nowicki B; Wikström HV; Swahn CG; Farde L
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Review: PSYCHOPHARMACOLOGY. 2018;235(5):1317-1334

The 5-HT1B receptor - a potential target for antidepressant treatment.

Tiger M; Varnäs K; Okubo Y; Lundberg J
Review: CLINICAL AND TRANSLATIONAL IMAGING. 2017;5(3):291-298

PET microdosing of CNS drugs

Schou M; Varnas K
Review: JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS. 2013;40(3):267-279

Modeling of PET data in CNS drug discovery and development.

Varnäs K; Varrone A; Farde L
Meeting abstract: NEUROIMAGE. 2010;52:S61-S62

Amphetamine decreases binding of the novel alpha2C-adrenoreceptor radioligand [11C]ORM-13070 in monkey brain

Finnema SJ; Varnas K; Stepanov V; Varrone A; Gulyas B; Arponen E; Helin S; Solin O; Haaparanta M; Sallinen J; Ingman K; Scheinin M; Farde L; Halldin C
Meeting abstract: NEUROIMAGE. 2010;52:S142

Quantification and wavelet-aided parametric imaging of cerebral amyloid using the HRRT PET-system and [18F]AZD4694

Cselenyi Z; Jonhagen ME; Forsberg A; Halldin C; Julin P; Schou M; Johnstroem P; Varnas K; Svensson S; Farde L
Corrigendum: PSYCHIATRY RESEARCH-NEUROIMAGING. 2009;171(3):258

Investigating possible subtypes of schizophrenia patients and controls based on brain cortical thickness (vol 164, pg 254, 2008)

Lawyer G; Nesvag R; Varnas K; Frigessi A; Agartz I
Published conference paper: PSYCHIATRIC GENETICS. 2008;18(4):177-183

Brain-derived neurotrophic factor polymorphisms and frontal cortex morphology in schizophrenia.

Varnäs K; Lawyer G; Jönsson EG; Kulle B; Nesvåg R; Hall H; Terenius L; Agartz I
Published conference paper: HUMAN BRAIN MAPPING. 2004;22(3):246-260

Autoradiographic distribution of serotonin transporters and receptor subtypes in human brain.

Varnäs K; Halldin C; Hall H

Employments

Affiliated to Research, Department of Clinical Neuroscience, Karolinska Institutet, 2023-2026

Degrees and Education

Doctor Of Philosophy, Department of Clinical Neuroscience, Karolinska Institutet, 2005

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