Staffan Rosenborg

Publications
CV
Public outreach and news

Articles

Article: LANCET MICROBE. 2024;5(4):e355-e365

Effect of tebipenem pivoxil hydrobromide on the normal gut microbiota of a healthy adult population in Sweden: a randomised controlled trial.

Sewunet T; Razavi M; Rosenborg S; Camporeale A; Nowak M; Melnick D; Gasink LB; Eckburg PB; Critchley IA; Nord CE; Giske CG
Article: LAKARTIDNINGEN. 2023;120:22097

Fanconis syndrom – en ovanlig biverkan av tenofovirdisoproxil.

Lodin K; Rosenborg S; Hemmingsson P
Article: LAKARTIDNINGEN. 2022;119:22017

[Janusmed Renal Function, an appreciated CDSS to support prescription of drugs and appropriate dosing in patients with renal impairment].

Justad H; Askfors Y; Shemeikka T; Rosenborg S; Veg A; Bárány P; Elinder C-G
Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2022;77(10):2718-2728

Population pharmacokinetics of apramycin from first-in-human plasma and urine data to support prediction of efficacious dose.

Zhao C; Chirkova A; Rosenborg S; Palma Villar R; Lindberg J; Hobbie SN; Friberg LE
Article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2022;130(4):492-500

Plasma concentrations of methylphenidate enantiomers in adults with ADHD and substance use disorder, with focus on high doses and relationship to carboxylesterase activity.

Arvidsson M; Franck J; Ackehed G; Pettersson Bergstrand M; Ekström L; Rosenborg S; Dahl M-L
Journal article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2022;322(2):E197

Corrigendum for Norgren et al., volume 318, 2020, p. E184-E188.
Article: FRONTIERS IN AGING NEUROSCIENCE. 2021;13:716594

Serum proBDNF Is Associated With Changes in the Ketone Body β-Hydroxybutyrate and Shows Superior Repeatability Over Mature BDNF: Secondary Outcomes From a Cross-Over Trial in Healthy Older Adults.

Norgren J; Daniilidou M; Kåreholt I; Sindi S; Akenine U; Nordin K; Rosenborg S; Ngandu T; Kivipelto M; Sandebring-Matton A
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2020;318(2):E184-E188

Capillary blood tests may overestimate ketosis: triangulation between three different measures of β-hydroxybutyrate.

Norgren J; Sindi S; Sandebring-Matton A; Kåreholt I; Akenine U; Nordin K; Rosenborg S; Ngandu T; Kivipelto M
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2020;76(2):229-237

Pharmacokinetics of methylphenidate and ritalinic acid in plasma correlations with exhaled breath and oral fluid in healthy volunteers.

Arvidsson M; Dahl M-L; Beck O; Ackehed G; Nordin K; Rosenborg S
Article: FRONTIERS IN NUTRITION. 2020;7:40

Ketosis After Intake of Coconut Oil and Caprylic Acid-With and Without Glucose: A Cross-Over Study in Healthy Older Adults.

Norgren J; Sindi S; Sandebring-Matton A; Kåreholt I; Daniilidou M; Akenine U; Nordin K; Rosenborg S; Ngandu T; Kivipelto M
Article: ACTA PHYSIOLOGICA. 2018;222(2)

High doses of anti-inflammatory drugs compromise muscle strength and hypertrophic adaptations to resistance training in young adults.

Lilja M; Mandić M; Apró W; Melin M; Olsson K; Rosenborg S; Gustafsson T; Lundberg TR
Article: MEDICINE. 2017;96(50):e9277

Mesalazine as a cause of fetal anemia and hydrops fetalis: A case report.

Ek S; Rosenborg S
Article: CLINICAL BIOCHEMISTRY. 2016;49(13-14):1024-1031

Experiences from using LC-MS/MS for analysis of immunosuppressive drugs in a TDM service.

Pohanka A; Rosenborg S; Lindh JD; Beck O
Article: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2016;60(7):4244-4251

Ecological Effect of Solithromycin on Normal Human Oropharyngeal and Intestinal Microbiota.

Rashid M-U; Rosenborg S; Panagiotidis G; Holm J; Söderberg Löfdal K; Weintraub A; Nord CE
Journal article: OPEN FORUM INFECTIOUS DISEASES. 2015;2(suppl_1):750

Ecological Effect of Ceftaroline/Avibactam on the Normal Human Intestinal Microbiota

Nord CE; Rashid M-U; Rosenborg S; Panagiotidis G; Löfdal KS; Weintraub A
Article: BIOCHEMICAL PHARMACOLOGY. 2015;98(3):502-510

First report on the pharmacokinetics of tramadol and O-desmethyltramadol in exhaled breath compared to plasma and oral fluid after a single oral dose.

Meyer MR; Rosenborg S; Stenberg M; Beck O
Article: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2015;59(8):4504-4509

Ecological Effect of Ceftaroline-Avibactam on the Normal Human Intestinal Microbiota.

Rashid M-U; Rosenborg S; Panagiotidis G; Söderberg-Löfdal K; Weintraub A; Nord CE
Article: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS. 2015;46(1):60-65

Ecological effect of ceftazidime/avibactam on the normal human intestinal microbiota.

Rashid M-U; Rosenborg S; Panagiotidis G; Löfdal KS; Weintraub A; Nord CE
Article: MEDICINE. 2014;93(7):e46

High phenobarbital clearance during continuous renal replacement therapy: a case report and pharmacokinetic analysis.

Rosenborg S; Saraste L; Wide K
Article: CLINICAL KIDNEY JOURNAL. 2014;7(2):151-155

Systematic conversion to generic tacrolimus in stable kidney transplant recipients.

Rosenborg S; Nordström A; Almquist T; Wennberg L; Bárány P
Article: LAKARTIDNINGEN. 2013;110(41):1809

[No given alternatives to clozapine in treatment-resistant schizophrenia].

Eriksen J; Rosenborg S
Article: STEM CELL RESEARCH. 2013;11(1):563-573

New potential cell source for hepatocyte transplantation: discarded livers from metabolic disease liver transplants.

Gramignoli R; Tahan V; Dorko K; Skvorak KJ; Hansel MC; Zhao W; Venkataramanan R; Ellis ECS; Jorns C; Ericzon B-G; Rosenborg S; Kuiper R; Soltys KA; Mazariegos GV; Fox IJ; Wilson EM; Grompe M; Strom SC
Article: LAKARTIDNINGEN. 2013;110(21):1030-1032

[Unclear on dose adjustment in renal impairment].

Asker-Hagelberg C; Rydberg D; Hentschke M; Holm L; Rosenborg S; Elinder C-G
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2013;69 Suppl 1:95-99

Characteristics and apprehensions of clinical pharmacologists in Swedish healthcare--a questionnaire study.

Wallerstedt SM; Rosenborg S
Article: THERAPEUTIC DRUG MONITORING. 2012;34(2):134-142

Quantification of tacrolimus and three demethylated metabolites in human whole blood using LC-ESI-MS/MS.

Dubbelboer IR; Pohanka A; Said R; Rosenborg S; Beck O
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2012;68(4):407-413

Omeprazole limited sampling strategies to predict area under the concentration-time curve ratios: implications for cytochrome P450 2C19 and 3A phenotyping.

Lawson EB; Wu JC; Baldwin RM; Ingelman-Sundberg M; Rosenborg S; Yim D-S; Yin OQP; Capparelli EV; Ma JD
Article: CLINICAL PHARMACOLOGY & THERAPEUTICS. 2010;88(3):343-346

Clinically significant CYP2C inhibition by noscapine but not by glucosamine.

Rosenborg S; Stenberg M; Otto S; Ostervall J; Masquelier M; Yue Q-Y; Bertilsson L; Eliasson E
Article: LAKARTIDNINGEN. 2010;107(7):444

[Cross reactivity between ACE inhibitors and angiotensin receptor blockers].

Rosenborg S
Article: LAKARTIDNINGEN. 2010;107(3):116-117

[Can oseltamivir (Tamiflu) be used in dialysis-requiring renal failure?].

Rosenborg S
Journal article: LAKARTIDNINGEN. 2009;106(43):2776-2777

[Omeprazole increases the risk of myocardial infarction in patients treated with clopidogrel].

Rosenborg S
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2008;64(12):1175-1179

Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects.

Ohlsson Rosenborg S; Mwinyi J; Andersson M; Baldwin RM; Pedersen RS; Sim SC; Bertilsson L; Ingelman-Sundberg M; Eliasson E
Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2008;65(5):767-774

Increased omeprazole metabolism in carriers of the CYP2C19*17 allele; a pharmacokinetic study in healthy volunteers.

Baldwin RM; Ohlsson S; Pedersen RS; Mwinyi J; Ingelman-Sundberg M; Eliasson E; Bertilsson L
Article: PEDIATRIC BLOOD & CANCER. 1998;31(2):66-72

Persistent B19 parvovirus infection in pediatric malignancies.

Broliden K; Tolfvenstam T; Ohlsson S; Henter JI
Article: ANTIBIOTICA ET CHEMOTHERAPIA. FORTSCHRITTE. ADVANCES. PROGR�S. 1996;48:105-112

Immune responses to the HIV rev regulatory gene.

Wahren B; Brytting MM; Engström G; Hinkula J; Levi M; Ståhle EL; Ohlsson S; Rudén U; Schwartz S
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Conference publication: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2019;75:S89-S90

Pharmacokinetics of methylphenidate in plasma, exhaled breath, oral fluid and dried blood spots after a single oral dose of ritalin 20 mg

Arvidsson M; Dahl M-L; Beck O; Rosenborg S; Nordin K; Lenk G
Conference publication: THERAPEUTIC DRUG MONITORING. 2013;35(5):667-668

Systematic Conversion to Generic Tacrolimus in Stable Kidney Transplant Patients

Rosenborg S; Nordstrom A; Almquist T; Wennberg L; Barany P
Conference publication: THERAPEUTIC DRUG MONITORING. 2011;33(4):530

Quantification of tacrolimus and its three mono-demethylated metabolites in human whole blood

Rosenborg S; Dubbelboer IR; Pohanka A; Said R; Beck O
Conference publication: CLINICAL PHARMACOLOGY & THERAPEUTICS. 2011;89:S61

LIMITED SAMPLING STRATEGIES (LSS) TO PREDICT OMEPRAZOLE TO OMEPRAZOLE SULFONE (OME/SULF) AUClast RATIO AS A BIOMARKER OF CYTOCHROME P450 (CYP) 3A ACTIVITY IN CYP2C19 EXTENSIVE METABOLIZERS (EMs)

Wu JC; Baldwin RM; Ingelman-Sundberg M; Rosenborg S; Yim DS; Yin OQ; Capparelli EV; Ma JD
Conference publication: CLINICAL PHARMACOLOGY & THERAPEUTICS. 2011;89:S57

LIMITATIONS OF LIMITED SAMPLING STRATEGY (LSS) FOR ESTIMATION OF OMEPRAZOLE (OME)-TO-5-HYDROXYOMEPRAZOLE (5OH) AREA UNDER THE CONCENTRATION TIME CURVE RATIO (AUCOME/AUC5OH) IN CYTOCHROME P450 (CYP) 2C19 EXTENSIVE METABOLIZERS (EMs)

Lawson EB; Baldwin RM; Ingelman-Sundberg M; Rosenborg S; Yim DS; Yin OQ; Capparelli EV; Ma JD
Thesis / dissertation: 2010

CYP2C-dependent drug metabolism in vivo : influence of genetics and drug interactions

Rosenborg, Staffan
Conference publication: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2009;105:72

CLINICALLY SIGNIFICANT CYP INHIBITION BY NOSCAPINE

Rosenborg S; Stenberg M; Yue Q-Y; Bertilsson L; Eliasson E
Letter: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2008;65(2):277-278

Noscapine may increase the effect of warfarin.

Ohlsson S; Holm L; Myrberg O; Sundström A; Yue Q-Y
Letter: CLINICAL PHARMACOLOGY & THERAPEUTICS. 2006;79(3):287-288

Accumulation of celecoxib with a 7-fold higher drug exposure in individuals homozygous for CYP2C9*3.

Lundblad MS; Ohlsson S; Johansson P; Lafolie P; Eliasson E

Employments

Adjunct Lecturer, Department of Laboratory Medicine, Karolinska Institutet, 2022-2025

Degrees and Education

Docent, Karolinska Institutet, 2022
Degree Of Doctor Of Philosophy, Department of Laboratory Medicine, Karolinska Institutet, 2010
University Medical Degree, Karolinska Institutet, 1996

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