Director, Center for Apheresis and Stem Cell Handling, Karolinska University Hospital
Associate professor in Renal Physiology, School of Medicine, Jiao Tong University, Shanghai (through KI)
Wallenberg Clinical Research Fellow 2014-2017
Translational research into uremic toxicity
We work with cell lines, primary cell cultures, transgenic animals (zebrafish and mice) and actual patient materials to discover novel pathophysiological pathways of relevance for patients with reduced renal function. Our data is generated using conventional and novel biomedical methods in combination with advanced imaging, proteomic analysis and transgenic animals.
About chronic kidney disease
Chronic kidney disease (CKD) and end-stage renal disease (ESRD) are significant public health problems in both developed and developing countries. Despite many ethiologies, the CKD phenotype is remarkably simillar and responsible for the premature death, elevated morbidity and very high costs of this patient group Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization.
N. Engl. J. Med. 2004 Sep;351(13):1296-305. In the US, nearly 25 percent of the Medicare budget is used to treat people with CKD and ESRD (http://www.usrds.org/).