Hong Qian, PhD., a group leader, was recruited to Center for hematology and Regenerative Medicine, Karolinska Institutet as an assistant professor in December, 2011. She received her Ph.D. degree in Stem Cell Biology from Lund University, Sweden (2007) and did a postdoc at Department of Clinical and Experimental Medicine, Linköping University, Sweden (2008-2011).
2004-2007. Ph.D. study in Stem Cell Biology from Lund University, Sweden.
2008-2011, postdoc at Department of Clinical and Experimental Medicine, Linköping University, Sweden (2008-2011).
Mesenchymal stem cells have become one of the most promising cell types in regenerative medicine. However, their exact cellular identity and in vivo functions remain poorly understood due to the fact that much of our current understanding of stromal precursor cells has been based on in vitro cultured cells whose characteristics may differ from their primary counterparts.
Our research program is focusing on identification and characterization of native mesenchymal stem and progenitor cells from bone marrow and other sources by using multi-color flow cytometry, transgenic mouse models as well as human materials.
We are aiming to identify in vivo activities of mesenchymal stem cells in bone marrow under physiological conditions such as normal hematopoiesis and under diseases including hematological disorders.
The potential findings from this research program may help to understand cellular mechanisms underlying regulation of hematopoiesis and to develop better stem cell-based therapeutic strategies in regenerative medicine.