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Gerald McInerney

Senior researcher

Visiting address : Nobelsväg 16 171 77 Stockholm, Sweden
Delivery address : Nobelsväg 16 171 77 Stockholm, Sweden

Publications

A Prime-Boost Vaccination Strategy in Cattle to Prevent Foot-and-Mouth Disease Using a "Single-Cycle" Alphavirus Vector and Empty Capsid Particles (vol 11, e0157435, 2016)
Gullberg M, Lohse L, Botner A, Mcinerney Gm, Burman A, Jackson T, et al
PLOS ONE 2017;12(3):e0173327-

Elongated and Shortened Peptidomimetic Inhibitors of the Proprotein Convertase Furin
Hardes K, Ivanova T, Thaa B, Mcinerney Gm, Klokk Ti, Sandvig K, et al
ChemMedChem 2017;12(8):613-620

A Prime-Boost Vaccination Strategy in Cattle to Prevent Foot-and-Mouth Disease Using a "Single-Cycle" Alphavirus Vector and Empty Capsid Particles
Gullberg M, Lohse L, Bøtner A, Mcinerney Gm, Burman A, Jackson T, et al
PloS one 2016;11(6):e0157435-

A Prime-Boost Vaccination Strategy in Cattle to Prevent Foot-and-Mouth Disease Using a "Single-Cycle" Alphavirus Vector and Empty Capsid Particles (vol 11, e0157435, 2016)
Gullberg M, Lohse L, Botner A, Mcinerney Gm, Burman A, Jackson T
PLOS ONE 2016;11(12):e0169025-

Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication
Schulte T, Liu L, Panas Md, Thaa B, Dickson N, Götte B, et al
Open biology 2016;6(7):-

Differential Phosphatidylinositol-3-KinaseAkt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization (vol 89, pg 11420, 2015)
Thaa B, Biasiotto R, Eng K, Neuvonen M, Gotte B, Rheinemann L, et al
JOURNAL OF VIROLOGY 2016;90(8):4256-

Effects of an In-Frame Deletion of the 6k Gene Locus from the Genome of Ross River Virus
Taylor A, Melton Jv, Herrero Lj, Thaa B, Karo-astover L, Gage Pw, et al
Journal of virology 2016;90(8):4150-9

G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits
Kedersha N, Panas Md, Achorn Ca, Lyons S, Tisdale S, Hickman T, et al
The Journal of cell biology 2016;212(7):845-60

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Klionsky Dj, Abdelmohsen K, Abe A, Abedin Mj, Abeliovich H, Arozena Aa, et al
AUTOPHAGY 2016;12(1):1-222

The Antiviral Alkaloid Berberine Reduces Chikungunya Virus-Induced Mitogen-Activated Protein Kinase Signaling
Varghese Fs, Thaa B, Amrun Sn, Simarmata D, Rausalu K, Nyman Ta, et al
Journal of virology 2016;90(21):9743-9757

Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization
Thaa B, Biasiotto R, Eng K, Neuvonen M, Götte B, Rheinemann L, et al
Journal of virology 2015;89(22):11420-37

FGDF motif regulation of stress granule formation
Mcinerney Gm
DNA and cell biology 2015;34(9):557-60

Methods for the characterization of stress granules in virus infected cells
Panas Md, Kedersha N, Mcinerney Gm
Methods (San Diego, Calif.) 2015;90():57-64

Protection of human myeloid dendritic cell subsets against influenza A virus infection is differentially regulated upon TLR stimulation
Baharom F, Thomas S, Bieder A, Hellmér M, Volz J, Sandgren Kj, et al
Journal of immunology (Baltimore, Md. : 1950) 2015;194(9):4422-30

Real-time resolution of point mutations that cause phenovariance in mice
Wang T, Zhan X, Bu Ch, Lyon S, Pratt D, Hildebrand S, et al
Proceedings of the National Academy of Sciences of the United States of America 2015;112(5):E440-9

Viral and cellular proteins containing FGDF motifs bind G3BP to block stress granule formation
Panas Md, Schulte T, Thaa B, Sandalova T, Kedersha N, Achour A, et al
PLoS pathogens 2015;11(2):e1004659-

The C-terminal repeat domains of nsP3 from the Old World alphaviruses bind directly to G3BP
Panas Md, Ahola T, Mcinerney Gm
Journal of virology 2014;88(10):5888-93

The host nonsense-mediated mRNA decay pathway restricts Mammalian RNA virus replication
Balistreri G, Horvath P, Schweingruber C, Zünd D, Mcinerney G, Merits A, et al
Cell host & microbe 2014;16(3):403-11

Autophagy researchers
Camougrand N, Mcinerney G, Proikas-cezanne T
AUTOPHAGY 2013;9(5):635-8

Influenza A virus-mediated priming enhances cytokine secretion by human dendritic cells infected with Streptococcus pneumoniae
Kuri T, Sörensen As, Thomas S, Karlsson Hedestam Gb, Normark S, Henriques-normark B, et al
Cellular microbiology 2013;15(8):1385-400

Accumulation of Autophagosomes in Semliki Forest Virus-Infected Cells Is Dependent on Expression of the Viral Glycoproteins
Eng Ke, Panas Md, Murphy D, Hedestam Gbk, Mcinerney Gm
JOURNAL OF VIROLOGY 2012;86(10):5674-85

A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity
Arnold Cn, Pirie E, Dosenovic P, Mcinerney Gm, Xia Y, Wang N, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2012;109(31):12286-93

Age-Dependent TLR3 Expression of the Intestinal Epithelium Contributes to Rotavirus Susceptibility
Pott J, Stockinger S, Torow N, Smoczek A, Lindner C, Mcinerney G, et al
PLOS PATHOGENS 2012;8(5):e1002670-

Guidelines for the use and interpretation of assays for monitoring autophagy
Klionsky Dj, Abdalla Fc, Abeliovich H, Abraham Rt, Acevedo-arozena A, Adeli K, et al
AUTOPHAGY 2012;8(4):445-544

Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection
Panas Md, Varjak M, Lulla A, Eng Ke, Merits A, Karlsson Hedestam Gb, et al
Molecular biology of the cell 2012;23(24):4701-12

Adenovirus type-35 vectors block human CD4(+) T-cell activation via CD46 ligation
Adams Wc, Gujer C, Mcinerney G, Gall Jgd, Petrovas C, Hedestam Gbk, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2011;108(18):7499-504

Multiple Polymorphisms Affect Expression and Function of the Neuropeptide S Receptor (NPSR1)
Anedda F, Zucchelli M, Schepis D, Hellquist A, Corrado L, D'alfonso S, et al
PLOS ONE 2011;6(12):e29523-

A Differential Role for Macropinocytosis in Mediating Entry of the Two Forms of Vaccinia Virus into Dendritic Cells
Sandgren Kj, Wilkinson J, Miranda-saksena M, Mcinerney Gm, Byth-wilson K, Robinson Pj, et al
PLOS PATHOGENS 2010;6(4):e1000866-

A mutation of Ikbkg causes immune deficiency without impairing degradation of I kappa B alpha
Siggs Om, Berger M, Krebs P, Arnold Cn, Eidenschenk C, Huber C, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2010;107(7):3046-51

A novel quantitative flow cytometry-based assay for autophagy
Eng Ke, Panas Md, Hedestam Gbk, Mcinerney Gm
AUTOPHAGY 2010;6(5):634-41

Direct Cleavage, Proteasomal Degradation and Sequestration: Three Mechanisms of Viral Subversion of Type I Interferon Responses
Mcinerney Gm, Hedestam Gbk
JOURNAL OF INNATE IMMUNITY 2009;1(6):599-606

Specific ligation to double-stranded RNA for analysis of cellular RNA :: RNA interactions
Faridani Or, Mcinerney Gm, Gradin K, Good L
NUCLEIC ACIDS RESEARCH 2008;36(16):e99-

Bone marrow dendritic cells internalize live RF-81 bovine rotavirus and rotavirus-like particles (RF 2/6-GFP-VLP and RF 8*2/6/7-VLP) but are only activated by live bovine rotavirus
Istrate C, Douagi I, Charpilienne A, Mcinerney Gm, Hidmark A, Johansen K, et al
SCANDINAVIAN JOURNAL OF IMMUNOLOGY 2007;65(6):494-502

Increased human immunodeficiency virus type 1 Env expression and antibody induction using an enhanced alphavirus vector
Forsell Mne, Mcinerney Gm, Dosenovic P, Hidmark As, Eriksson C, Liljestorm P, et al
JOURNAL OF GENERAL VIROLOGY 2007;:2774-9

Role of interferon regulatory factor 3 in type I interferon responses in rotavirus-infected dendritic cells and fibroblasts
Douagi I, Mcinerney Ga, Hidmark As, Miriallis V, Johansen K, Svensson L, et al
JOURNAL OF VIROLOGY 2007;81(6):2758-68

Semliki forest virus nonstructural protein 2 is involved in suppression of the type I interferon response
Breakwell L, Dosenovic P, Hedestam Gbk, D'amato M, Liljestrom P, Fazakerley J, et al
JOURNAL OF VIROLOGY 2007;81(16):8677-84

Early alpha/beta interferon production by myeloid dendritic cells in response to UV-inactivated virus requires viral entry and interferon regulatory factor 3 but not MyD88
Hidmark As, Mcinerney Gm, Nordstrom Ekl, Douagi I, Werner Km, Liljestrom P, et al
JOURNAL OF VIROLOGY 2005;79(16):10376-85

Efficient expansion of HIV-1-specific T cell responses by homologous immunization with recombinant Semliki Forest virus particles
Sundback M, Douagi I, Dayaraj C, Forsell Mne, Nordstrom Ekl, Mcinerney Gm, et al
VIROLOGY 2005;341(2):190-202

Importance of eIF2 alpha phosphorylation assembly in alphavirus translation and stress granule regulation
Mcinerney Gm, Kedersha Nl, Kaufman Rj, Anderson P, Liljestrom P
MOLECULAR BIOLOGY OF THE CELL 2005;16(8):3753-63

Reversible acid-induced inactivation of the membrane fusion protein of Semliki Forest virus
Waarts Bl, Smit Jm, Aneke Ojc, Mcinerney Gm, Liljestrom P, Bittman R, et al
JOURNAL OF VIROLOGY 2005;79(12):7942-8

Semliki Forest virus produced in the absence of the 6K protein has an altered spike structure as revealed by decreased membrane fusion capacity
Mcinerney Gm, Smit Jm, Liljestrom P, Wilschut J
VIROLOGY 2004;325(2):200-6

Foot-and-mouth disease virus 3C protease induces cleavage of translation initiation factors eIF4A and eIF4G within infected cells
Belsham Gj, Mcinerney Gm, Ross-smith N
JOURNAL OF VIROLOGY 2000;74(1):272-80

Replication-competent foot-and-mouth disease virus RNAs lacking capsid ceding sequences
Mcinerney Gm, King Amq, Ross-smith N, Belsham Gj
JOURNAL OF GENERAL VIROLOGY 2000;:1699-702

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