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About me

In my current research position, I target the resolution of biological questions through integrative bioinformatics, with a focus on epigenomics. I have been involved in developing and testing different analysis pipelines but also in evaluating biological questions through comprehensive data analysis.

Research description

Epigenomics of Multiple Sclerosis

Publications

Comprehensive mapping of the effects of azacitidine on DNA methylation, repressive/permissive histone marks and gene expression in primary cells from patients with MDS and MDS-related disease
Tobiasson M, Abdulkadir H, Lennartsson A, Katayama S, Marabita F, De Paepe A, et al
Oncotarget 2017;8(17):28812-28825

Epigenetic research in multiple sclerosis: progress, challenges, and opportunities
Zheleznyakova Gy, Piket E, Marabita F, Pahlevan Kakhki M, Ewing E, Ruhrmann S, et al
Physiological genomics 2017;49(9):447-461

Expression of Transient Receptor Potential Channels in the Purified Human Pancreatic β-Cells
Marabita F, Islam Ms
Pancreas 2017;46(1):97-101

Guidelines for Developing Successful Short Advanced Courses in Systems Medicine and Systems Biology
Gomez-cabrero D, Marabita F, Tarazona S, Cano I, Roca J, Conesa A, et al
Cell systems 2017;5(3):168-175

Phosphoproteomics Reveals Regulatory T Cell-Mediated DEF6 Dephosphorylation That Affects Cytokine Expression in Human Conventional T Cells
Joshi Rn, Binai Na, Marabita F, Sui Z, Altman A, Heck Ajr, et al
Frontiers in immunology 2017;8():1163-

Smoking induces DNA methylation changes in Multiple Sclerosis patients with exposure-response relationship
Marabita F, Almgren M, Sjöholm Lk, Kular L, Liu Y, James T, et al
Scientific reports 2017;7(1):14589-

Transcriptomics and methylomics of CD4-positive T cells in arsenic-exposed women
Engström K, Wojdacz Tk, Marabita F, Ewels P, Käller M, Vezzi F, et al
Archives of toxicology 2017;91(5):2067-2078

Human regulatory T cells rapidly rewire the phosphoproteome of suppressed conventional T cells
Joshi Rn, Binai N, Marabita F, Tegner J, Schmidt A
SCANDINAVIAN JOURNAL OF IMMUNOLOGY 2016;83(5):376-377

Integrative molecular profiling during human induced regulatory T cell (iTreg) generation reveals novel regulators of FOXP3
Schmidt A, Marabita F, Johansson H, Lehtio J, Eriksson M, Elias S, et al
SCANDINAVIAN JOURNAL OF IMMUNOLOGY 2016;83(5):353-353

Normalization of circulating microRNA expression data obtained by quantitative real-time RT-PCR
Marabita F, De Candia P, Torri A, Tegnér J, Abrignani S, Rossi Rl
Briefings in bioinformatics 2016;17(2):204-12

Serum microRNAs as novel biomarkers for primary sclerosing cholangitis and cholangiocarcinoma
Bernuzzi F, Marabita F, Lleo A, Carbone M, Mirolo M, Marzioni M, et al
Clinical and experimental immunology 2016;185(1):61-71

Differentially Expressed Plasma miRNAs as Novel Biomarkers for the Early Detection of Primary Sclerosing Cholangitis and Cholangiocarcinoma
Bernuzzi F, Marabita F, Lleo A, Bianchi I, Mirolo M, Marzioni M, et al
HEPATOLOGY 2015;:507A-508A

IN VITRO AZACITIDINE CULTURE INDUCES DNA DEMETHYLATION AND INCREASED MRNA-LEVELS IN PRIMARY MDS PROGENITOR CELLS
Abdulkadir H, Tobiasson M, Lennartsson A, Katayama S, Marabita F, Karimi M, et al
LEUKEMIA RESEARCH 2015;:S69-S69

An integrative analysis reveals coordinated reprogramming of the epigenome and the transcriptome in human skeletal muscle after training
Lindholm Me, Marabita F, Gomez-cabrero D, Rundqvist H, Ekström Tj, Tegnér J, et al
Epigenetics 2014;9(12):1557-69

Interaction between PNPLA3 I148M variant and age at infection in determining fibrosis progression in chronic hepatitis C
De Nicola S, Dongiovanni P, Aghemo A, Cheroni C, D'ambrosio R, Pedrazzini M, et al
PloS one 2014;9(8):e106022-

Systems Medicine: from molecular features and models to the clinic in COPD
Gomez-cabrero D, Menche J, Cano I, Abugessaisa I, Huertas-migueláñez M, Tenyi A, et al
Journal of translational medicine 2014;12 Suppl 2():S4-

A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data
Teschendorff Ae, Marabita F, Lechner M, Bartlett T, Tegner J, Gomez-cabrero D, et al
Bioinformatics (Oxford, England) 2013;29(2):189-96

An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation450 BeadChip platform
Marabita F, Almgren M, Lindholm Me, Ruhrmann S, Fagerström-billai F, Jagodic M, et al
Epigenetics 2013;8(3):333-46

Identification of serum and tissue micro-RNA expression profiles in different stages of inflammatory bowel disease
Iborra M, Bernuzzi F, Correale C, Vetrano S, Fiorino G, Beltrán B, et al
Clinical and experimental immunology 2013;173(2):250-8

Intracellular Modulation, Extracellular Disposal and Serum Increase of MiR-150 Mark Lymphocyte Activation
De Candia P, Torri A, Gorletta T, Fedeli M, Bulgheroni E, Cheroni C, et al
PLOS ONE 2013;8(9):e75348-

Identification of New Autoantigens by Protein Array Indicates a Role for IL4 Neutralization in Autoimmune Hepatitis
Zingaretti C, Arigo M, Cardaci A, Moro M, Crosti M, Sinisi A, et al
MOLECULAR & CELLULAR PROTEOMICS 2012;11(12):1885-97

Distinct microRNA signatures in human lymphocyte subsets and enforcement of the naive state in CD4(+) T cells by the microRNA miR-125b
Rossi Rl, Rossetti G, Wenandy L, Curti S, Ripamonti A, Bonnal Rjp, et al
NATURE IMMUNOLOGY 2011;12(8):796-803

Fibrosis progression in patients with chronic hepatitis C is not influenced by IL28B polymorphisms
Aghemo A, Marabita F, De Nicola S, Rumi Mg, Cheroni C, Scavelli R, et al
DIGESTIVE AND LIVER DISEASE 2011;:S88-S88

FIBROSIS PROGRESSION IN PATIENTS WITH CHRONIC HEPATITIS C IS NOT INFLUENCED BY IL28B POLYMORPHISMS
Aghemo A, Marabita F, De Nicola S, Rumi Mg, Cheroni C, Scavelli R, et al
JOURNAL OF HEPATOLOGY 2011;:S519-S519

Genetic Variation in the Interleukin-28B Gene Is Not Associated With Fibrosis Progression in Patients With Chronic Hepatitis C and Known Date of Infection
Marabita F, Aghemo A, De Nicola S, Rumi Mg, Cheroni C, Scavelli R, et al
HEPATOLOGY 2011;54(4):1127-34

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